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  1. Book: Prävention kardiovaskulärer Erkrankungen und Atherosklerose

    Kuhlmann, Inga / Chin, Dawn / Rimbach, Gerald

    (essentials)

    2014  

    Author's details Inga Kuhlmann ; Dawn Chin ; Gerald Rimbach
    Series title essentials
    Keywords Apolipoprotein E ; Nahrungsfaktoren für die Gefäßgesundheit ; Risikofaktoren ; Herz-Kreislauf-Erkrankungen ; Stickstoffmonoxid-Synthasen
    Language German
    Size VIII, 32 S. : graph. Darst.
    Publisher Springer
    Publishing place Wiesbaden
    Publishing country Germany
    Document type Book
    HBZ-ID HT018610463
    ISBN 978-3-658-08359-5 ; 978-3-658-08358-8 ; 3-658-08358-1 ; 3-658-08359-X
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2015 A 3238 available for loan (reading room) Lesesaal EG

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  2. Book ; Online: Prävention kardiovaskulärer Erkrankungen und Atherosklerose

    Kuhlmann, Inga / Chin, Dawn / Rimbach, Gerald

    (essentials)

    2014  

    Abstract: Inga Kuhlmann, Dawn Chin und Gerald Rimbach geben eine Einführung zu Stickstoffmonoxid-Synthasen und deren Bedeutung in der Prävention und Pathogenese kardiovaskulärer Erkrankungen. Außerdem liefern sie einen Überblick zu Apolipoprotein E und dessen ... ...

    Author's details Inga Kuhlmann; Dawn Chin; Gerald Rimbach
    Series title essentials
    Abstract Inga Kuhlmann, Dawn Chin und Gerald Rimbach geben eine Einführung zu Stickstoffmonoxid-Synthasen und deren Bedeutung in der Prävention und Pathogenese kardiovaskulärer Erkrankungen. Außerdem liefern sie einen Überblick zu Apolipoprotein E und dessen Bedeutung in der Entwicklung einer Atherosklerose. Die Autoren geben abschließend Empfehlungen für eine gesunde Ernährung zur Prävention von Herz-Kreislauf-Erkrankungen. Der Inhalt Molekulare Mechanismen der Atherosklerose Stickstoffmonoxid-Synthasen (NOS) und deren Bedeutung in der Pathogenese kardiovaskulärer Erkrankungen Risikofaktoren Bedeutung von Nahrungsfaktoren für die Gefäßgesundheit Apolipoprotein E-Genotyp und Gefäßgesundheit Die Zielgruppen Dozenten und Studenten der Ernährungswissenschaften mit den Schwerpunkten Humanernährung und Lebensmittelkunde PraktikerInnen, die sich mit dem Thema Ernährung, kardiovaskuläre Erkrankungen und Atherosklerose befassen Die Autoren Inga Kuhlmann ist Ernährungswissenschaftlerin und derzeit in der Lebensmittelindustrie tätig. Dr. Dawn Chin ist wissenschaftliche Mitarbeiterin  am Institut für Humanernährung und Lebensmittelkunde an der Universität Kiel. Prof. Dr. Gerald Rimbach ist Professor für Lebensmittelwissenschaft am Institut für Humanernährung und Lebensmittelkunde an der Universität Kiel
    Keywords Biochemistry ; Human genetics ; Medicine
    Language German
    Size Online-Ressource (VIII, 32 S.)
    Publisher Springer Spektrum
    Publishing place Wiesbaden
    Document type Book ; Online
    ISBN 9783658083588 ; 9783658083595 ; 3658083581 ; 365808359X
    DOI 10.1007/978-3-658-08359-5
    Database Former special subject collection: coastal and deep sea fishing

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  3. Book ; Online: Prävention kardiovaskulärer Erkrankungen und Atherosklerose

    Kuhlmann, Inga / Chin, Dawn / Rimbach, Gerald

    (essentials)

    2014  

    Abstract: Inga Kuhlmann, Dawn Chin und Gerald Rimbach geben eine Einführung zu Stickstoffmonoxid-Synthasen und deren Bedeutung in der Prävention und Pathogenese kardiovaskulärer Erkrankungen. Außerdem liefern sie einen Überblick zu Apolipoprotein E und dessen ... ...

    Author's details von Inga Kuhlmann, Dawn Chin, Gerald Rimbach
    Series title essentials
    Abstract Inga Kuhlmann, Dawn Chin und Gerald Rimbach geben eine Einführung zu Stickstoffmonoxid-Synthasen und deren Bedeutung in der Prävention und Pathogenese kardiovaskulärer Erkrankungen. Außerdem liefern sie einen Überblick zu Apolipoprotein E und dessen Bedeutung in der Entwicklung einer Atherosklerose. Die Autoren geben abschließend Empfehlungen für eine gesunde Ernährung zur Prävention von Herz-Kreislauf-Erkrankungen. Der Inhalt Molekulare Mechanismen der Atherosklerose Stickstoffmonoxid-Synthasen (NOS) und deren Bedeutung in der Pathogenese kardiovaskulärer Erkrankungen Risikofaktoren Bedeutung von Nahrungsfaktoren für die Gefäßgesundheit Apolipoprotein E-Genotyp und Gefäßgesundheit Die Zielgruppen Dozenten und Studenten der Ernährungswissenschaften mit den Schwerpunkten Humanernährung und Lebensmittelkunde PraktikerInnen, die sich mit dem Thema Ernährung, kardiovaskuläre Erkrankungen und Atherosklerose befassen Die Autoren Inga Kuhlmann ist Ernährungswissenschaftlerin und derzeit in der Lebensmittelindustrie tätig. Dr. Dawn Chin ist wissenschaftliche Mitarbeiterin  am Institut für Humanernährung und Lebensmittelkunde an der Universität Kiel. Prof. Dr. Gerald Rimbach ist Professor für Lebensmittelwissenschaft am Institut für Humanernährung und Lebensmittelkunde an der Universität Kiel
    Keywords Biochemistry ; Human genetics ; Medicine
    Language German
    Size Online-Ressource
    Publisher Springer Spektrum
    Publishing place s.l.
    Document type Book ; Online
    ISBN 9783658083588 ; 9783658083595 ; 3658083581 ; 365808359X
    DOI 10.1007/978-3-658-08359-5
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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    Order via subito

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    Inter-library loan at ZB MED

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  4. Article ; Online: Apolipoprotein E genotype and hepatitis C, HIV and herpes simplex disease risk

    Nebel Almut / Huebbe Patricia / Minihane Anne / Kuhlmann Inga / Rimbach Gerald

    Lipids in Health and Disease, Vol 9, Iss 1, p

    a literature review

    2010  Volume 8

    Abstract: Abstract Apolipoprotein E is a polymorphic and multifunctional protein with numerous roles in lipoprotein metabolism. The three common isoforms apoE2, apoE3 and apoE4 show isoform-specific functional properties including different susceptibilities to ... ...

    Abstract Abstract Apolipoprotein E is a polymorphic and multifunctional protein with numerous roles in lipoprotein metabolism. The three common isoforms apoE2, apoE3 and apoE4 show isoform-specific functional properties including different susceptibilities to diseases. ApoE4 is an accepted risk factor for Alzheimer's disease and cardiovascular disorders. Recently, associations between apoE4 and infectious diseases have been demonstrated. This review summarises how apoE4 may be involved in the infection incidence and associated pathologies of specific infectious diseases, namely hepatitis C, human immunodeficiency virus disease and herpes simplex. ApoE4 seems to be protective against chronic hepatitis C virus infection and retards fibrosis progression. In contrast apoE4 enhances the fusion rate of human immunodeficiency virus with target cell membranes, resulting in accelerated cell entry and faster disease progression. Its association with human immunodeficiency virus-associated dementia remains controversial. Regarding herpes simplex virus infection, apoE4 intensifies virus latency and is associated with increased oxidative damage of the central nervous system, and there is some evidence that herpes simplex virus infection in combination with the apoE4 genotype may be associated with an increased risk of Alzheimer's disease. In addition to reviewing available data from human trials, evidence derived from a variety of cell culture and animal models are considered in this review in order to provide mechanistic insights into observed association between apoE4 genotype and viral disease infection and pathology.
    Keywords Physiology ; QP1-981 ; Science ; Q ; DOAJ:Physiology ; DOAJ:Biology ; DOAJ:Biology and Life Sciences
    Subject code 610
    Language English
    Publishing date 2010-01-01T00:00:00Z
    Publisher BioMed Central
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  5. Article ; Online: Apolipoprotein E genotype and hepatitis C, HIV and herpes simplex disease risk: a literature review.

    Kuhlmann, Inga / Minihane, Anne Marie / Huebbe, Patricia / Nebel, Almut / Rimbach, Gerald

    Lipids in health and disease

    2010  Volume 9, Page(s) 8

    Abstract: Apolipoprotein E is a polymorphic and multifunctional protein with numerous roles in lipoprotein metabolism. The three common isoforms apoE2, apoE3 and apoE4 show isoform-specific functional properties including different susceptibilities to diseases. ... ...

    Abstract Apolipoprotein E is a polymorphic and multifunctional protein with numerous roles in lipoprotein metabolism. The three common isoforms apoE2, apoE3 and apoE4 show isoform-specific functional properties including different susceptibilities to diseases. ApoE4 is an accepted risk factor for Alzheimer's disease and cardiovascular disorders. Recently, associations between apoE4 and infectious diseases have been demonstrated. This review summarises how apoE4 may be involved in the infection incidence and associated pathologies of specific infectious diseases, namely hepatitis C, human immunodeficiency virus disease and herpes simplex.ApoE4 seems to be protective against chronic hepatitis C virus infection and retards fibrosis progression. In contrast apoE4 enhances the fusion rate of human immunodeficiency virus with target cell membranes, resulting in accelerated cell entry and faster disease progression. Its association with human immunodeficiency virus-associated dementia remains controversial. Regarding herpes simplex virus infection, apoE4 intensifies virus latency and is associated with increased oxidative damage of the central nervous system, and there is some evidence that herpes simplex virus infection in combination with the apoE4 genotype may be associated with an increased risk of Alzheimer's disease. In addition to reviewing available data from human trials, evidence derived from a variety of cell culture and animal models are considered in this review in order to provide mechanistic insights into observed association between apoE4 genotype and viral disease infection and pathology.
    MeSH term(s) Adult ; Aged ; Alleles ; Alzheimer Disease/genetics ; Apolipoprotein E3/genetics ; Apolipoprotein E4/genetics ; Apolipoproteins E/genetics ; Apolipoproteins E/metabolism ; Female ; Genotype ; HIV/genetics ; HIV/metabolism ; Hepatitis C/genetics ; Herpes Simplex/complications ; Herpes Simplex/genetics ; Humans ; Male ; Middle Aged ; Risk
    Chemical Substances Apolipoprotein E3 ; Apolipoprotein E4 ; Apolipoproteins E
    Language English
    Publishing date 2010-01-28
    Publishing country England
    Document type Journal Article ; Review
    ISSN 1476-511X
    ISSN (online) 1476-511X
    DOI 10.1186/1476-511X-9-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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