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Article ; Online: The 'mushroom': a simple and safe technique to avoid cerebrospinal fluid leak after endoscopic third ventriculostomy.

Lo, W B / Afshari, F T / Rodrigues, D / Kulkarni, A V

Annals of the Royal College of Surgeons of England

2020 Volume 102, Issue 4, Page(s) 312–313

MeSH term(s)	Cerebrospinal Fluid Leak/etiology ; Cerebrospinal Fluid Leak/prevention & control ; Endoscopy/adverse effects ; Endoscopy/methods ; Gelatin Sponge, Absorbable/administration & dosage ; Hemostatics/administration & dosage ; Humans ; Ventriculostomy/adverse effects ; Ventriculostomy/methods
Chemical Substances	Hemostatics
Language	English
Publishing date	2020-01-22
Publishing country	England
Document type	Journal Article
ZDB-ID	80044-2
ISSN	1478-7083 ; 0035-8843
ISSN (online)	1478-7083
ISSN	0035-8843
DOI	10.1308/rcsann.2020.0006
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Article ; Online: Correlation of fetal ventricular size and need for postnatal cerebrospinal fluid diversion surgery in open spina bifida.

Agrawal, S / Al-Refai, A / Abbasi, N / Kulkarni, A V / Pruthi, V / Drake, J / Ryan, G / Van Mieghem, T

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology

2021 Volume 59, Issue 6, Page(s) 799–803

Abstract: Objectives: Open spina bifida is a common cause of hydrocephalus in the postnatal period. In-utero closure of the fetal spinal defect decreases the need for postnatal cerebrospinal fluid (CSF) diversion surgery. Good prenatal predictors of the need for ... ...

Abstract	Objectives: Open spina bifida is a common cause of hydrocephalus in the postnatal period. In-utero closure of the fetal spinal defect decreases the need for postnatal cerebrospinal fluid (CSF) diversion surgery. Good prenatal predictors of the need for postnatal CSF diversion surgery are currently lacking. In this study, we aimed to assess the association of fetal ventriculomegaly and its progression over the course of pregnancy with the rate of postnatal hydrocephalus requiring intervention. Methods: In this retrospective study, fetuses with a prenatal diagnosis of open spina bifida were assessed longitudinally. Ventricular diameter, as well as other potential predictors of the need for postnatal CSF diversion surgery, were compared between fetuses undergoing prenatal closure and those undergoing postnatal repair. Results: The diameter of the lateral ventricle increased significantly throughout gestation in both groups, but there was no difference in maximum ventricular diameter at first or last assessment between fetuses undergoing prenatal closure and those undergoing postnatal repair. There was no significant difference in the rate of progression of ventriculomegaly between the two groups, with a mean progression rate of 0.83 ± 0.5 mm/week in the prenatal-repair group and 0.6 ± 0.6 mm/week in the postnatal-repair group (P = 0.098). Fetal repair of open spina bifida was associated with a lower rate of postnatal CSF diversion surgery (P < 0.001). In all subjects, regardless of whether they had prenatal or postnatal surgery, the severity of ventriculomegaly at first and last assessments was associated independently with the need for postnatal CSF diversion surgery (P = 0.005 and P = 0.001, respectively), with a greater need for surgery in fetuses with larger ventricular size, even after controlling for gestational age at assessment. Conclusions: In fetuses with open spina bifida, fetal ventricular size increases regardless of whether spina bifida closure is performed prenatally or postnatally, but the need for CSF diversion surgery is significantly lower in those undergoing prenatal repair. Ventriculomegaly is associated independently with the need for postnatal CSF diversion in fetuses with open spina bifida, irrespective of timing of closure. © 2021 International Society of Ultrasound in Obstetrics and Gynecology.
MeSH term(s)	Female ; Fetus/surgery ; Humans ; Hydrocephalus/diagnostic imaging ; Hydrocephalus/etiology ; Hydrocephalus/surgery ; Meningomyelocele/surgery ; Pregnancy ; Retrospective Studies ; Spina Bifida Cystica/diagnostic imaging ; Spina Bifida Cystica/surgery ; Spinal Dysraphism/complications ; Spinal Dysraphism/diagnostic imaging ; Spinal Dysraphism/surgery
Language	English
Publishing date	2021-09-14
Publishing country	England
Document type	Journal Article
ZDB-ID	1073183-0
ISSN	1469-0705 ; 0960-7692
ISSN (online)	1469-0705
ISSN	0960-7692
DOI	10.1002/uog.24767
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Article ; Online: Ultrasound assisted synthesis of methyl butyrate using heterogeneous catalyst.

Dange, P N / Kulkarni, A V / Rathod, V K

Ultrasonics sonochemistry

2015 Volume 26, Page(s) 257–264

Abstract: Ultrasound assisted esterification of butyric acid with methanol was investigated in an ultrasound irradiated isothermal batch reactor using acid ion-exchange resin (amberlyst-15) as a catalyst. Effect of parameters such as temperature (323-353 K), ... ...

Abstract	Ultrasound assisted esterification of butyric acid with methanol was investigated in an ultrasound irradiated isothermal batch reactor using acid ion-exchange resin (amberlyst-15) as a catalyst. Effect of parameters such as temperature (323-353 K), catalyst loading (0-8.5%w/w), alcohol to acid ratio, M (2-6), ultrasound power (0-145 W), duty cycle (0-85%) and amount of molecular sieves added (0-11%w/w) on the rate of reaction was studied. At optimized parameters, a maximum conversion of 91.64% was obtained in 120 min in presence of ultrasound. Experimental kinetic data were correlated by using Eley-Rideal (ER) and Langmuir-Hinshelwood-Hougen-Watson (LHH W) models taking into account reverse reaction. Studies showed that single site LHHW with reactants and products both adsorbing on catalyst surface was most suited for the obtained experimental data. Activation energy determined based on heterogeneous kinetics was in the range 49.31-57.54 kJ/mol while it was 18.29 kJ/mol using homogeneous model.
Language	English
Publishing date	2015-09
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1208333-1
ISSN	1873-2828 ; 1350-4177
ISSN (online)	1873-2828
ISSN	1350-4177
DOI	10.1016/j.ultsonch.2015.02.014
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Article ; Online: In vitro induction of multiple shoots and plant regeneration in cotton (Gossypium hirsutum L.).

Agrawal, D C / Banerjee, A K / Kolala, R R / Dhage, A B / Kulkarni, A V / Nalawade, S M / Hazra, S / Krishnamurthy, K V

Plant cell reports

2019 Volume 16, Issue 9, Page(s) 647–652

Abstract: Induction of multiple shoots in cotton (Gossypium hirsutum L. cv. Anjali-LRK 516) has been achieved with cotyledonary nodes devoid of cotyledons and apical meristems. Explants from 35-day-old seedlings yielded the maximum number of shoots (4.7 shoots/ ... ...

Abstract	Induction of multiple shoots in cotton (Gossypium hirsutum L. cv. Anjali-LRK 516) has been achieved with cotyledonary nodes devoid of cotyledons and apical meristems. Explants from 35-day-old seedlings yielded the maximum number of shoots (4.7 shoots/explant) using Murashige and Skoog (MS) basal medium supplemented with 6-benzylaminopurine and kinetin (2.5 mg/1 each). Explants from 35-day-old seedlings raised in glass bottles produced a higher number of multiple shoots (8.3 shoots/explant) than those grown in glass tubes and cultured on the same shoot induction medium. Elongation of multiple shoots was obtained on liquid or agar MS basal medium without phytohormones. In vitro shoots were rooted on half-strength agar-solidified MS basal medium or with 0.05 or 0.1 mg/1 naphthaleneacetic acid. Hardening and survival of tissue culture plantlets was 95% under greenhouse conditions.
Language	English
Publishing date	2019-02-06
Publishing country	Germany
Document type	Journal Article
ZDB-ID	8397-5
ISSN	1432-203X ; 0721-085X ; 0721-7714
ISSN (online)	1432-203X
ISSN	0721-085X ; 0721-7714
DOI	10.1007/BF01275508
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Article: Interventional radiological treatment of hepatocellular carcinoma: an update.

Shrimal, Anurag / Prasanth, Madhu / Kulkarni, A V

The Indian journal of surgery

2011 Volume 74, Issue 1, Page(s) 91–99

Abstract: Hepatocellular carcinoma is the commonest primary liver tumor and its incidence is on an increase.Transplantation and surgical resection are the gold standard curative treatment options but less than 20%patients are surgical candidates because of ... ...

Abstract	Hepatocellular carcinoma is the commonest primary liver tumor and its incidence is on an increase.Transplantation and surgical resection are the gold standard curative treatment options but less than 20%patients are surgical candidates because of advanced liver disease and/or co-morbidities.Various interventional radiological procedures have been developed and intensively investigated for treatment of inoperable HCC.This review summarizes the various interventional radiological treatments in HCC including patient selection, procedural considerations and response evaluation. Transarterial chemoembolization, radioembolization and radiofrequency ablation are mainly discussed.
Language	English
Publishing date	2011-12-13
Publishing country	India
Document type	Journal Article
ZDB-ID	138063-1
ISSN	0972-2068 ; 0019-5650
ISSN	0972-2068 ; 0019-5650
DOI	10.1007/s12262-011-0377-4
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Article ; Online: Percutaneous hepatic venous stenting for menorrhagia in Budd-Chiari syndrome.

Dhumane, P W / Kulkarni, A V / Waravdekar, G / Shah, S R

Liver international : official journal of the International Association for the Study of the Liver

2013 Volume 33, Issue 10, Page(s) 1607

MeSH term(s)	Adult ; Angiography, Digital Subtraction ; Budd-Chiari Syndrome/pathology ; Female ; Hepatic Veins/physiopathology ; Hepatic Veins/surgery ; Humans ; Menorrhagia/prevention & control ; Menorrhagia/surgery ; Regional Blood Flow/physiology ; Stents ; Tomography, X-Ray Computed
Language	English
Publishing date	2013-11
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	2102783-3
ISSN	1478-3231 ; 1478-3223
ISSN (online)	1478-3231
ISSN	1478-3223
DOI	10.1111/liv.12183
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Book ; Online: Changes in seasonal snow cover in Hindu Kush-Himalayan region

Gurung, D. R. / Kulkarni, A. V. / Giriraj, A. / Aung, K. S. / Shrestha, B. / Srinivasan, J.

eISSN: 1994-0424

2018

Abstract: The changes in seasonal snow covered area in the Hindu Kush-Himalayan (HKH) region have been examined using Moderate – resolution Imaging Spectroradiometer (MODIS) 8-day standard snow products. The average snow covered area of the HKH region based on ... ...

Abstract	The changes in seasonal snow covered area in the Hindu Kush-Himalayan (HKH) region have been examined using Moderate – resolution Imaging Spectroradiometer (MODIS) 8-day standard snow products. The average snow covered area of the HKH region based on satellite data from 2000 to 2010 is 0.76 million km 2 which is 18.23% of the total geographical area of the region. The linear trend in annual snow cover from 2000 to 2010 is −1.25±1.13%. This is in consistent with earlier reported decline of the decade from 1990 to 2001. A similar trend for western, central and eastern HKH region is 8.55±1.70%, +1.66% ± 2.26% and 0.82±2.50%, respectively. The snow covered area in spring for HKH region indicates a declining trend (−1.04±0.97%). The amount of annual snowfall is correlated with annual seasonal snow cover for the western Himalaya, indicating that changes in snow cover are primarily due to interannual variations in circulation patterns. Snow cover trends over a decade were also found to vary across seasonally and the region. Snow cover trends for western HKH are positive for all seasons. In central HKH the trend is positive (+15.53±5.69%) in autumn and negative (−03.68&plusmn3.01) in winter. In eastern HKH the trend is positive in summer (+3.35±1.62%) and autumn (+7.74±5.84%). The eastern and western region of HKH has an increasing trend of 10% to 12%, while the central region has a declining trend of 12% to 14% in the decade between 2000 and 2010. Snow cover depletion curve plotted for the hydrological year 2000–2001 reveal peaks in the month of February with subsidiary peaks observed in November and December in all three regions of the HKH.
Subject code	910 ; 551
Language	English
Publishing date	2018-09-26
Publishing country	de
Document type	Book ; Online
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Article ; Online: Predictive Value of MRI in Diagnosing Brain AVM Recurrence after Angiographically Documented Exclusion in Children.

Jhaveri, A / Amirabadi, A / Dirks, P / Kulkarni, A V / Shroff, M M / Shkumat, N / Krings, T / Pereira, V M / Rea, V / Muthusami, P

AJNR. American journal of neuroradiology

2019 Volume 40, Issue 7, Page(s) 1227–1235

Abstract: Background and purpose: MRI is routinely performed following brain AVM after treatment in children. Our aim was to determine the predictive values of contrast-enhanced MR imaging and TOF-MRA for brain AVM recurrence in children, compared with ... ...

Abstract	Background and purpose: MRI is routinely performed following brain AVM after treatment in children. Our aim was to determine the predictive values of contrast-enhanced MR imaging and TOF-MRA for brain AVM recurrence in children, compared with conventional angiography and the role of 3D rotational angiography-MR imaging fusion in these cases. Materials and methods: We included all pediatric patients with brain AVMs during an 18-year period with angiographically documented obliteration after treatment. Patients underwent 3T MR imaging, including contrast-enhanced MR imaging, TOF-MRA, and conventional angiography, with a subset undergoing 3D rotational angiography. The predictive values of contrast-enhanced MR imaging and TOF-MRA for brain AVM recurrence were determined. CTA sections reconstructed from 3D rotational angiography were coregistered with and fused to 3D-T1WI for analysis. Results: Thirty-nine children (10.8 ± 3.9 years of age; range, 2-17 years; male/female ratio, 19:20; mean Spetzler-Martin grade, 1.9 ± 0.6) met the inclusion criteria. Of these, 13 had angiographically confirmed brain AVM recurrence, 8 following surgery and 5 following embolization. Sensitivity, specificity, and positive and negative predictive values for recurrence were the following: contrast-enhanced MR imaging: 84.6%, 38.5%, 40.7%, 81.8%; TOF-MRA: 50.0%, 96.1%, 85.7%, 79.3%; both: 75.0%, 90.9%, 85.7%, 83.3%. 3D rotational angiography-MR imaging fused images confirmed or excluded recurrence in all available cases (13/13). Embolization-only treatment was a significant predictor of recurrence (OR = 32.4, Conclusions: MR imaging is useful for surveillance after brain AVM treatment in children, but conventional angiography is required for definitive diagnosis of recurrence. TOF-MRA and contrast-enhanced MR imaging provide complementary information for determining brain AVM recurrence and should be interpreted in conjunction. 3D rotational angiography-MR imaging fusion increases the diagnostic confidence regarding brain AVM recurrence and is therefore suited for intraoperative neuronavigation.
MeSH term(s)	Adolescent ; Arteriovenous Fistula/diagnostic imaging ; Arteriovenous Fistula/therapy ; Brain/diagnostic imaging ; Child ; Child, Preschool ; Female ; Humans ; Imaging, Three-Dimensional/methods ; Intracranial Arteriovenous Malformations/diagnostic imaging ; Intracranial Arteriovenous Malformations/therapy ; Magnetic Resonance Angiography/methods ; Magnetic Resonance Imaging/methods ; Male ; Neuroimaging/methods ; Predictive Value of Tests ; Recurrence ; Retrospective Studies
Keywords	covid19
Language	English
Publishing date	2019-06-27
Publishing country	United States
Document type	Journal Article
ZDB-ID	603808-6
ISSN	1936-959X ; 0195-6108
ISSN (online)	1936-959X
ISSN	0195-6108
DOI	10.3174/ajnr.A6093
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Article: Cross calibration of INSAT 3A CCD channel radiances with IRS P6 AWiFS sensor

SINGH, S K / BHATTACHARYA, B K / KULKARNI, A V

Journal of earth system science. 2013 Aug., v. 122, no. 4

2013

Abstract: Indian National Satellite (INSAT) 3A was launched in the year 2003 with communication and remote sensing payloads. The later payloads contain very high resolution radiometer (VHRR) and charge coupled devices (CCD) camera. In this paper, post-launch ... ...

Abstract	Indian National Satellite (INSAT) 3A was launched in the year 2003 with communication and remote sensing payloads. The later payloads contain very high resolution radiometer (VHRR) and charge coupled devices (CCD) camera. In this paper, post-launch calibration of INSAT 3A CCD is discussed. A cross radiometric calibration was carried out with well calibrated advanced wide field of view sensor (AWiFS) of Indian Remote Sensing Satellite (IRS P6). Three concurrent scenes of December, January and February were used in this study. Calibration was carried out under different land cover classes such as snow, vegetation, forest, water and cloud. Regression analysis suggests correlation coefficient of 0.95, 0.92 and 0.60 for Red, NIR and SWIR channels with slope values 1.839, 1.589 and 2.232, respectively. New calibration coefficients were used to estimate at-sensor radiance and reflectance in all the three channels. Dynamic range of reflectances was found to be improved by using new calibration coefficients. Normalized difference snow index and vegetation index (NDSI and NDVI) have shown an improvement with new coefficients and were found closer to represent in situ data of different land covers and cloud.
Keywords	correlation ; earth system science ; forests ; land cover ; radiometry ; reflectance ; regression analysis ; remote sensing ; snow ; vegetation index
Language	English
Dates of publication	2013-08
Size	p. 957-966.
Publishing place	Springer-Verlag
Document type	Article
ZDB-ID	2081712-5
ISSN	0973-774X ; 0253-4126
ISSN (online)	0973-774X
ISSN	0253-4126
DOI	10.1007/s12040-013-0318-7
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Article ; Online: Production of camptothecin in cultures of Chonemorpha grandiflora.

Kulkarni, A V / Patwardhan, A A / Lele, U / Malpathak, N P

Pharmacognosy research

2011 Volume 2, Issue 5, Page(s) 296–299

Abstract: Background: Chonemorpha grandiflora (Syn. Chonemorpha fragrans (Apocynaceae) is an endangered medicinal plant. It is used in different preparations, such as sudarsanasavam and kumaryasavam used in Kerala Ayurvedic system. C. grandiflora is used for the ... ...

Abstract	Background: Chonemorpha grandiflora (Syn. Chonemorpha fragrans (Apocynaceae) is an endangered medicinal plant. It is used in different preparations, such as sudarsanasavam and kumaryasavam used in Kerala Ayurvedic system. C. grandiflora is used for the treatment of fever and stomach disorders. Phytochemical investigations have revealed the presence of steroidal alkaloids, such as chonemorphine and funtumafrine in C. grandiflora. Camptothecin, a well-known anticancer alkaloid has been detected in ethanolic extracts of stem with bark and callus cultures derived from C. grandiflora. Methods: Callus cultures of C. grandiflora were raised on Murashige and Skoog's medium supplemented with 2, 4-D. Stem with bark and callus were used for phytochemical analysis mainly the alkaloids. Detection and identification of camptothecin was carried out using thin-layer chromatography (TLC), high-performance thin-layer chromatography, (HPTLC) and high-performance liquid chromatography (HPLC). Results: An important anticancer alkaloid, camptothecin was detected in ethanolic extracts of stem with bark and callus cultures of C. grandiflora. camptothecin content was 0.013 mg/g in stem with bark and 0.003 mg/g in callus. Conclusion: This is the first report on in vivo and in vitro production of camptothecin in C. grandiflora. Camptothecin is known to occur only in six plant sources so, alternative sources for camptothecin are needed. Thus of C. grandiflora could be a new promising alternative source of camptothecin.
Language	English
Publishing date	2011-04-27
Publishing country	India
Document type	Journal Article
ZDB-ID	2580264-1
ISSN	0974-8490 ; 0976-4836
ISSN (online)	0974-8490
ISSN	0976-4836
DOI	10.4103/0974-8490.72327
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