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  1. Book ; Online ; E-Book: Opto-VLSI Devices and Circuits for Biomedical and Healthcare Applications

    Kumar, Ankur

    2024  

    Abstract: The text comprehensively discusses the latest Opto-VLSI devices and circuits useful for healthcare and biomedical applications. It further emphasizes the importance of smart technologies such as artificial intelligence, machine learning, and the ... ...

    Author's details edited by Ankur Kumar [and five others]
    Abstract "The text comprehensively discusses the latest Opto-VLSI devices and circuits useful for healthcare and biomedical applications. It further emphasizes the importance of smart technologies such as artificial intelligence, machine learning, and the internet of things for the biomedical and healthcare industries"--
    Keywords Artificial intelligence
    Subject code 610.285
    Language English
    Size 1 online resource (218 pages)
    Publisher Taylor & Francis Group, LLC
    Publishing place Boca Raton, FL
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 1-00-343113-5 ; 1-000-93234-6 ; 1-003-43113-5 ; 9781032392837 ; 978-1-00-343113-8 ; 978-1-000-93234-8 ; 978-1-003-43113-8 ; 1032392835
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online: Vision Transformer Compression with Structured Pruning and Low Rank Approximation

    Kumar, Ankur

    2022  

    Abstract: Transformer architecture has gained popularity due to its ability to scale with large dataset. Consequently, there is a need to reduce the model size and latency, especially for on-device deployment. We focus on vision transformer proposed for image ... ...

    Abstract Transformer architecture has gained popularity due to its ability to scale with large dataset. Consequently, there is a need to reduce the model size and latency, especially for on-device deployment. We focus on vision transformer proposed for image recognition task (Dosovitskiy et al., 2021), and explore the application of different compression techniques such as low rank approximation and pruning for this purpose. Specifically, we investigate a structured pruning method proposed recently in Zhu et al. (2021) and find that mostly feedforward blocks are pruned with this approach, that too, with severe degradation in accuracy. We propose a hybrid compression approach to mitigate this where we compress the attention blocks using low rank approximation and use the previously mentioned pruning with a lower rate for feedforward blocks in each transformer layer. Our technique results in 50% compression with 14% relative increase in classification error whereas we obtain 44% compression with 20% relative increase in error when only pruning is applied. We propose further enhancements to bridge the accuracy gap but leave it as a future work.
    Keywords Computer Science - Computer Vision and Pattern Recognition
    Subject code 518
    Publishing date 2022-03-25
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Performance comparison of instrument automation pipelines using different programming languages.

    Kumar, Ankur / Goswami, Mayank

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 18579

    Abstract: The article presents a performance analysis of fully automated, in-house developed 2D ultrasound computerized tomography systems using different programming languages. The system is fully automated in four programming languages: LabVIEW, MATLAB, C and ... ...

    Abstract The article presents a performance analysis of fully automated, in-house developed 2D ultrasound computerized tomography systems using different programming languages. The system is fully automated in four programming languages: LabVIEW, MATLAB, C and Python. It includes codes for sensors, instruments interfacing, real-time control, synchronized data acquisition, simultaneous raw data processing and analysis. Launch performance, eight performance indices and runtime performance are used for the analysis. It is found that C utilizes the least processing power and executes fewer I/O processes to perform the same task. In runtime analysis (data acquisition and real-time control), LabVIEW (365.69 s) performed best in comparison to MATLAB (623.83 s), Python (1505.54 s), and C (1252.03 s) to complete the experiment without data processing. However, in the experiment with data processing, MATLAB (640.33 s) performed best in comparison to LabVIEW (731.91 s), Python (1520.01 s) and C (1930.15 s). Python performed better in establishing faster interfacing and RAM usage. The study provides a methodology to select optimal programming languages for instrument automation-related aspects to optimize the available resources.
    Language English
    Publishing date 2023-10-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-45849-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The first report on the assessment of maximum acceptable daily intake (MADI) of pesticides for humans using intelligent consensus predictions.

    Kumar, Ankur / Ojha, Probir Kumar / Roy, Kunal

    Environmental science. Processes & impacts

    2024  

    Abstract: Direct or indirect consumption of pesticides and their related products by humans and other living organisms without safe dosing may pose a health risk. The risk may arise after a short/long time which depends on the nature and amount of chemicals ... ...

    Abstract Direct or indirect consumption of pesticides and their related products by humans and other living organisms without safe dosing may pose a health risk. The risk may arise after a short/long time which depends on the nature and amount of chemicals consumed. Therefore, the maximum acceptable daily intake of chemicals must be calculated to prevent these risks. In the present work, regression-based quantitative structure-activity relationship (QSAR) models were developed using 39 pesticides with maximum acceptable daily intake (MADI) for humans as the endpoint. From the statistical results (
    Language English
    Publishing date 2024-04-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 2703814-2
    ISSN 2050-7895 ; 2050-7887
    ISSN (online) 2050-7895
    ISSN 2050-7887
    DOI 10.1039/d4em00059e
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    In stock of ZB MED Bonn / Germany

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  5. Article ; Online: Pramlintide an Adjunct to Insulin Therapy: Challenges and Recent Progress in Delivery.

    Kommera, Sai Pradyuth / Kumar, Ankur / Chitkara, Deepak / Mittal, Anupama

    The Journal of pharmacology and experimental therapeutics

    2024  Volume 388, Issue 1, Page(s) 81–90

    Abstract: Dysregulation of various glucoregulatory hormones lead to failure of insulin monotherapy in patients with diabetes mellitus due to various reasons, including severe hypoglycemia, glycemic hypervariability, and an increased risk of microvascular ... ...

    Abstract Dysregulation of various glucoregulatory hormones lead to failure of insulin monotherapy in patients with diabetes mellitus due to various reasons, including severe hypoglycemia, glycemic hypervariability, and an increased risk of microvascular complications. However, pramlintide as an adjunct to insulin therapy enhances glucagon suppression and thereby offers improved glycemic control. Clinical studies have shown that pramlintide improves glycemic control, reduces postprandial glucose excursions, and promotes weight loss in patients with type 1 and type 2 diabetes. Although clinical benefits of pramlintide are well reported, there still exists a high patient resistance for the therapy, as separate injections for pramlintide and insulin must be administered. Although marketed insulin formulations generally demonstrate a peak action in 60-90 minutes, pramlintide elicits its peak concentration at around 20-30 minutes after administration. Thus, owing to the significant differences in pharmacokinetics of exogenously administered pramlintide and insulin, the therapy fails to elicit its action otherwise produced by the endogenous hormones. Hence, strategies such as delaying the release of pramlintide by using inorganic polymers like silica, synthetic polymers like polycaprolactone, and lipids have been employed. Also, approaches like noncovalent conjugation, polyelectrolyte complexation, and use of amphiphilic excipients for codelivery of insulin and pramlintide have been explored to address the issues with pramlintide delivery and improve patient adherence to the therapy. This approach may usher in a new era of diabetes management, offering patients multiple options to tailor their treatment and improve their quality of life. SIGNIFICANCE STATEMENT: To our knowledge, this is the first report that summarizes various challenges in insulin and pramlintide codelivery and strategies to overcome them. The paper also provides deeper insights into various novel formulation strategies for pramlintide that could further broaden the reader's understanding of peptide codelivery.
    MeSH term(s) Humans ; Insulin ; Diabetes Mellitus, Type 2/drug therapy ; Hypoglycemic Agents/pharmacology ; Hypoglycemic Agents/therapeutic use ; Diabetes Mellitus, Type 1 ; Quality of Life ; Polymers ; Blood Glucose
    Chemical Substances Insulin ; pramlintide (D3FM8FA78T) ; Hypoglycemic Agents ; Polymers ; Blood Glucose
    Language English
    Publishing date 2024-01-02
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 3106-9
    ISSN 1521-0103 ; 0022-3565
    ISSN (online) 1521-0103
    ISSN 0022-3565
    DOI 10.1124/jpet.123.001679
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uf I Zs.40: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Chronic aquatic toxicity assessment of diverse chemicals on Daphnia magna using QSAR and chemical read-across.

    Kumar, Ankur / Kumar, Vinay / Ojha, Probir Kumar / Roy, Kunal

    Regulatory toxicology and pharmacology : RTP

    2024  Volume 148, Page(s) 105572

    Abstract: We have modeled here chronic Daphnia toxicity taking pNOEC (negative logarithm of no observed effect concentration in mM) and ... ...

    Abstract We have modeled here chronic Daphnia toxicity taking pNOEC (negative logarithm of no observed effect concentration in mM) and pEC
    MeSH term(s) Animals ; Daphnia magna ; Quantitative Structure-Activity Relationship ; Ecosystem ; Daphnia ; Water Pollutants, Chemical/toxicity
    Chemical Substances Water Pollutants, Chemical
    Language English
    Publishing date 2024-02-05
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 604672-1
    ISSN 1096-0295 ; 0273-2300
    ISSN (online) 1096-0295
    ISSN 0273-2300
    DOI 10.1016/j.yrtph.2024.105572
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1711: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  7. Article: Dengue outbreak update in India: 2022.

    Singh, Nitin / Singh, Amresh Kumar / Kumar, Ankur

    Indian journal of public health

    2023  Volume 67, Issue 1, Page(s) 181–183

    Abstract: Dengue is an emerging illness in India, where it is endemic in some areas and sometimes causes yearly epidemics. Each dengue outbreak starts with high death and morbidity, which has a significant socioeconomic impact. As of September 30, 2022, India had ... ...

    Abstract Dengue is an emerging illness in India, where it is endemic in some areas and sometimes causes yearly epidemics. Each dengue outbreak starts with high death and morbidity, which has a significant socioeconomic impact. As of September 30, 2022, India had 63,280 dengue cases, according to information provided by the National Centre for Vector Borne Diseases Control. North India is most severely impacted by each outbreak. In Uttar Pradesh, the state with the most population in India, there have been 2060 confirmed cases of dengue and 1 mortality till September 2022 reported. Patients are being reported from semi-urban, rural, and urban areas. It is essential to properly monitor disease cases through disease surveillance in order to ensure prompt case management if dengue outbreak control is to be achieved. An efficient diagnostic approach for early diagnosis is urgently required to reduce the severity of the sickness, the length of the hospital stay, and clinical consequences.
    MeSH term(s) Humans ; Dengue/epidemiology ; India/epidemiology ; Disease Outbreaks ; Epidemics ; Rural Population
    Language English
    Publishing date 2023-04-11
    Publishing country India
    Document type Journal Article
    ZDB-ID 800737-8
    ISSN 2229-7693 ; 0019-557X
    ISSN (online) 2229-7693
    ISSN 0019-557X
    DOI 10.4103/ijph.ijph_1517_22
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    In stock of ZB MED Cologne/Königswinter

    Zs.B 760: Show issues Location:
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  8. Article ; Online: Epithelioid trophoblastic tumors: a diagnostic challenge.

    Kumar, Ankur / Diwan, Himanshi / Sharma, Anila / Kamboj, Meenakshi

    International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

    2023  Volume 33, Issue 1, Page(s) 132–134

    MeSH term(s) Pregnancy ; Female ; Humans ; Gestational Trophoblastic Disease/diagnosis ; Trophoblastic Neoplasms/diagnosis ; Trophoblastic Neoplasms/therapy ; Uterine Neoplasms/diagnosis
    Language English
    Publishing date 2023-01-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 1070385-8
    ISSN 1525-1438 ; 1048-891X
    ISSN (online) 1525-1438
    ISSN 1048-891X
    DOI 10.1136/ijgc-2022-004027
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3198: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Cell Painting Gallery: an open resource for image-based profiling.

    Weisbart, Erin / Kumar, Ankur / Arevalo, John / Carpenter, Anne E / Cimini, Beth A / Singh, Shantanu

    ArXiv

    2024  

    Language English
    Publishing date 2024-02-03
    Publishing country United States
    Document type Preprint
    ISSN 2331-8422
    ISSN (online) 2331-8422
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Diagnostic precision of Truenat® technique and co-relation of ALT levels with HBV-DNA viral load among HBsAg positive patients at a tertiary care hospital in Eastern Uttar Pradesh.

    Kumari, Sarita / Gautam, Bechan Kumar / Singh, Amresh Kumar / Gaur, Vivek / Kumar, Ankur

    Iranian journal of microbiology

    2024  Volume 16, Issue 1, Page(s) 132–138

    Abstract: Background and objectives: In India, it is estimated that there are 40 million people suffering from Hepatitis B virus (HBV). Quantification of the viral burden is an important laboratory tool in the management. However, widespread use of different HBV- ... ...

    Abstract Background and objectives: In India, it is estimated that there are 40 million people suffering from Hepatitis B virus (HBV). Quantification of the viral burden is an important laboratory tool in the management. However, widespread use of different HBV-DNA assays is still affected by the high cost and variable diagnostic precision. The present study was conducted to evaluate the diagnostic precision and co-relation of ALT levels with HBV-DNA by Truenat®-PCR.
    Materials and methods: In this prospective cross-sectional study a total of 567 serums were collected from patients by rapid HBsAg, and processed for liver function tests (LFT). The viral HBV-DNA amplification detection was carried out through by Truenat®-PCR test.
    Results: Out of 567 samples, 452 samples were found to be positive by both rapid and Truenat®-PCR and 106 were negative for HBV-DNA followed by 9 invalid. High ALT level found in 73% of positive patients who had HBV-DNA level (>100000 copies/ml) which is significantly higher in 447 patients as compared to those have below ≤100000 copies/ml.
    Conclusion: Truenat®-PCR technique is a highly sensitive and can be performed with low resources for effective control of HBV infection. Evaluation of HBV-DNA levels and serum ALT levels showed a significant proportion of patient harbored ongoing viral replication and disease progression.
    Language English
    Publishing date 2024-04-26
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2652849-6
    ISSN 2008-4447 ; 2008-3289
    ISSN (online) 2008-4447
    ISSN 2008-3289
    DOI 10.18502/ijm.v16i1.14882
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