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  1. Article ; Online: Transcatheter Therapy for Mitral Valve Stenosis.

    Kumar, Kris / Simpson, Timothy

    Interventional cardiology clinics

    2024  Volume 13, Issue 2, Page(s) 271–278

    Abstract: Mitral valve stenosis remains highly prevalent among the US population although with dramatically shifting demographics. The significance of rheumatic mitral disease in developing nations persists, despite improvements in preventative measures and early ... ...

    Abstract Mitral valve stenosis remains highly prevalent among the US population although with dramatically shifting demographics. The significance of rheumatic mitral disease in developing nations persists, despite improvements in preventative measures and early detection, and its presence in developed countries is still evident as observed through international migration. In addition, the substantial growth in the aging population with a heightened occurrence of concurrent cardiovascular risk factors is leading to an increased prevalence of chronic calcific degeneration and degeneration of previously repaired or replaced valves. This article aims to review various transcatheter therapies in the treatment of mitral valve stenosis.
    MeSH term(s) Humans ; Aged ; Mitral Valve Stenosis/diagnosis ; Mitral Valve Stenosis/surgery
    Language English
    Publishing date 2024-02-02
    Publishing country Netherlands
    Document type Journal Article ; Review
    ISSN 2211-7466
    ISSN (online) 2211-7466
    DOI 10.1016/j.iccl.2024.01.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Antiplatelet Agents in Acute ST Elevation Myocardial Infarction.

    Kumar, Kris / Golwala, Harsh

    The American journal of medicine

    2022  Volume 135, Issue 6, Page(s) 697–708

    Abstract: Platelet aggregation and thrombus formation represent the basic mechanism for clinical, electrocardiographic, and biomarker changes consistent with acute coronary syndrome. Various oral and intravenous formulations of platelet function inhibitors have ... ...

    Abstract Platelet aggregation and thrombus formation represent the basic mechanism for clinical, electrocardiographic, and biomarker changes consistent with acute coronary syndrome. Various oral and intravenous formulations of platelet function inhibitors have been developed to help decrease platelet aggregation due to acute atherosclerotic plaque rupture. In this article, we review the various mechanisms, pharmacokinetics/pharmacodynamics, and the key clinical trials related to the platelet inhibitors that form the basis for current recommendations of their use in the ST elevation myocardial infarction guidelines by the American College of Cardiology/American Heart Association.
    MeSH term(s) Acute Coronary Syndrome/drug therapy ; Anterior Wall Myocardial Infarction ; Humans ; Platelet Aggregation Inhibitors/therapeutic use ; ST Elevation Myocardial Infarction/drug therapy ; Thrombosis/drug therapy
    Chemical Substances Platelet Aggregation Inhibitors
    Language English
    Publishing date 2022-02-22
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 80015-6
    ISSN 1555-7162 ; 1873-2178 ; 0002-9343 ; 1548-2766
    ISSN (online) 1555-7162 ; 1873-2178
    ISSN 0002-9343 ; 1548-2766
    DOI 10.1016/j.amjmed.2022.01.042
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  3. Article ; Online: The role of statin therapy in COVID-19.

    Daniels, Lori B / Kumar, Kris

    Expert review of cardiovascular therapy

    2022  Volume 20, Issue 6, Page(s) 415–417

    MeSH term(s) COVID-19/drug therapy ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/pharmacology ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use ; SARS-CoV-2
    Chemical Substances Hydroxymethylglutaryl-CoA Reductase Inhibitors
    Language English
    Publishing date 2022-05-30
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 2192343-7
    ISSN 1744-8344 ; 1477-9072
    ISSN (online) 1744-8344
    ISSN 1477-9072
    DOI 10.1080/14779072.2022.2081548
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  4. Article ; Online: Introducing CCI FIT BITS-A new home for fellows-in-training.

    Kumar, Kris / Ya'Qoub, Lina / Simpson, Timothy F

    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

    2022  Volume 100, Issue 3, Page(s) 480

    MeSH term(s) Fellowships and Scholarships ; Humans ; Treatment Outcome
    Language English
    Publishing date 2022-06-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1459995-8
    ISSN 1522-726X ; 1522-1946
    ISSN (online) 1522-726X
    ISSN 1522-1946
    DOI 10.1002/ccd.30302
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    Zs.A 1226: Show issues Location:
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  5. Article ; Online: Novel method for left ventricular unloading utilizing percutaneous pulmonary artery drainage in cardiorespiratory failure due to COVID-19 infection.

    Kumar, Kris / Coonse, Kendra / Zakhary, Bishoy / Cigarroa, Joaquin E

    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

    2022  Volume 100, Issue 1, Page(s) 175–178

    Abstract: Left ventricular (LV) unloading is an important concept in patients undergoing peripheral venoarterial extracorporeal membrane oxygenation (VA-ECMO). We present a case of a 32-year-old male in acute cardiorespiratory collapse due to coronavirus disease ( ... ...

    Abstract Left ventricular (LV) unloading is an important concept in patients undergoing peripheral venoarterial extracorporeal membrane oxygenation (VA-ECMO). We present a case of a 32-year-old male in acute cardiorespiratory collapse due to coronavirus disease (COVID-19) who underwent VA-ECMO cannulation in the setting of cardiogenic shock and acute respiratory distress syndrome. Due to inability to utilize percutaneous LV assist device (pLVAD) for LV unloading due to small end diastolic dimension, alternative strategies were explored. A traditionally utilized right ventricular support device, the ProTek Duo (TandemLife, Pittsburgh, PA), was utilized to drain the pulmonary artery, leading to improvement in parameters for cardiogenic shock. To our knowledge, this is the first case in which a ProTek Duo has been utilized in conjunction with VA-ECMO to provide LV unloading in support of a patient in cardiogenic shock. This method can be employed in future challenging situations where pLVAD is not feasible.
    MeSH term(s) Adult ; COVID-19/complications ; Drainage/methods ; Heart Failure/therapy ; Heart Failure/virology ; Humans ; Male ; Pulmonary Artery ; Respiratory Insufficiency/therapy ; Respiratory Insufficiency/virology ; Shock, Cardiogenic/therapy ; Treatment Outcome
    Language English
    Publishing date 2022-04-21
    Publishing country United States
    Document type Case Reports
    ZDB-ID 1459995-8
    ISSN 1522-726X ; 1522-1946
    ISSN (online) 1522-726X
    ISSN 1522-1946
    DOI 10.1002/ccd.30212
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    Zs.A 1226: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: The Role of Coronary Catheterization Laboratory in Post-Resuscitation Care of Patients Without ST Elevation Myocardial Infarction.

    Kumar, Kris / Lotun, Kapil

    Current cardiology reviews

    2018  Volume 14, Issue 2, Page(s) 92–96

    Abstract: Background: Out of hospital cardiac arrest management of patients with non-ST myocardial infarction per current American Heart Association and European Resuscitation Council guidelines leave the decision in regard to early angiography up to the ... ...

    Abstract Background: Out of hospital cardiac arrest management of patients with non-ST myocardial infarction per current American Heart Association and European Resuscitation Council guidelines leave the decision in regard to early angiography up to the physician operators. Guidelines are clear on the positive impact of early intervention on survival and improvement on left ventricular function in patients presenting with cardiac arrest and ST elevation myocardial infarction on electrocardiogram. This review aims to analyze the data that current guidelines are based upon in regards to out of hospital cardiac arrest with electrocardiogram findings of non-ST elevation myocardial infarction as well as review of other clinical trials that support early angiography and reperfusion strategies.
    Conclusion: Analysis of current literature shows that early coronary evaluation in patients with no finding of ST elevation on ECG can help improve survival in patients suffering out of hospital cardiac arrest.
    MeSH term(s) Cardiac Catheterization/methods ; Cardiopulmonary Resuscitation/methods ; Female ; Humans ; Male ; Treatment Outcome
    Language English
    Publishing date 2018-05-08
    Publishing country United Arab Emirates
    Document type Journal Article ; Review
    ISSN 1875-6557
    ISSN (online) 1875-6557
    DOI 10.2174/1573403X14666180507154107
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  7. Article: Right Atrial Thrombosis Provoked by Central Venous Catheter: A Case Report.

    Prudhvi, Kalyan / Kumar, Kris / Jonnadula, Jayasree / Janardhanan, Rajesh

    Cureus

    2020  Volume 12, Issue 7, Page(s) e9027

    Abstract: Intracardiac thrombi are not uncommon, but right atrial (RA) thrombi are exceedingly rare. Thrombi can lead to a variety of complications, such as systemic and pulmonary embolism. While various imaging modalities are helpful in the diagnosis, an ... ...

    Abstract Intracardiac thrombi are not uncommon, but right atrial (RA) thrombi are exceedingly rare. Thrombi can lead to a variety of complications, such as systemic and pulmonary embolism. While various imaging modalities are helpful in the diagnosis, an echocardiogram is the most commonly used one. Principle management of the condition involves anticoagulation. However, management can vary among different patient groups, depending on the location and size of thrombi. We present a case of an RA thrombosis due to dilation of the atria and trauma from an infected central venous catheter in a patient with a past medical history of pulmonary artery hypertension (PAH).
    Language English
    Publishing date 2020-07-06
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.9027
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  8. Article ; Online: Novel technique of performing multivessel PCI through an Impella sheath.

    Kumar, Kris / Reddy, Sridhar / Acharya, Deepak / Lotun, Kapildeo

    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

    2019  Volume 96, Issue 1, Page(s) 117–120

    Abstract: A 69-year-old woman with diabetes was found to have multi-vessel coronary artery disease and underwent 5-vessel coronary artery bypass grafting. Patient had persistent cardiogenic shock postoperatively despite intra-aortic balloon pump and escalating ... ...

    Abstract A 69-year-old woman with diabetes was found to have multi-vessel coronary artery disease and underwent 5-vessel coronary artery bypass grafting. Patient had persistent cardiogenic shock postoperatively despite intra-aortic balloon pump and escalating pressor requirements. Electrocardiogram showed new ischemic changes and the patient was urgently taken to the catheterization lab for coronary angiography and placement of an Impella CP for higher degree of hemodynamic support via the left femoral artery. Due to limitations in vascular access the Impella CP sheath was utilized for vascular access for diagnostic angiography and coronary intervention concurrently with ongoing Impella CP support. The first obtuse marginal had severe proximal disease and was treated with percutaneous coronary intervention (PCI) with a drug eluting stent. To our knowledge, this case is the first in which successful diagnostic angiography as well as multi-vessel PCI was performed via an Impella sheath while concurrently using the percutaneous mechanical circulatory support system of the Impella CP. Multiple guide catheters and a pigtail catheter were successfully passed via the Impella CP sheath to perform PCI. This novel method of vascular access could be an important tool to use in high-risk patients with limitations in access sites and decrease potential bleeding complications by limiting the number of arterial punctures.
    MeSH term(s) Aged ; Cardiac Catheterization/adverse effects ; Cardiac Catheterization/instrumentation ; Cardiac Catheters ; Catheterization, Peripheral ; Coronary Artery Bypass/adverse effects ; Coronary Artery Disease/diagnostic imaging ; Coronary Artery Disease/physiopathology ; Coronary Artery Disease/therapy ; Drug-Eluting Stents ; Female ; Heart-Assist Devices ; Hemodynamics ; Humans ; Percutaneous Coronary Intervention/adverse effects ; Percutaneous Coronary Intervention/instrumentation ; Punctures ; Shock, Cardiogenic/diagnosis ; Shock, Cardiogenic/etiology ; Shock, Cardiogenic/physiopathology ; Shock, Cardiogenic/therapy ; Treatment Outcome ; Ventricular Function, Left
    Language English
    Publishing date 2019-11-07
    Publishing country United States
    Document type Case Reports
    ZDB-ID 1459995-8
    ISSN 1522-726X ; 1522-1946
    ISSN (online) 1522-726X
    ISSN 1522-1946
    DOI 10.1002/ccd.28583
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    Zs.A 1226: Show issues Location:
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  9. Article ; Online: Spontaneous coronary artery dissection of the left anterior descending artery in a patient with COVID-19 infection.

    Kumar, Kris / Vogt, Joshua C / Divanji, Punag H / Cigarroa, Joaquin E

    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

    2020  Volume 97, Issue 2, Page(s) E249–E252

    Abstract: A 48-year-old woman with a past medical history of migraines and hyperlipidemia presented due to severe retrosternal chest pain with no other associated signs or symptoms. The patient was hemodynamically stable and was found to have an elevated troponin ... ...

    Abstract A 48-year-old woman with a past medical history of migraines and hyperlipidemia presented due to severe retrosternal chest pain with no other associated signs or symptoms. The patient was hemodynamically stable and was found to have an elevated troponin with electrocardiogram showing no ischemic changes. Computed tomography of the coronary arteries showed a left dominant system with dissection extending from the mid-to-distal left anterior descending (LAD) artery. The patient was subsequently discharged on medical therapy but returned 3 days later due to worsening chest pain. Electrocardiogram revealed inferior and anteroseptal ST segment changes with peak troponin of 14.9 ng/ml (reference range <0.80 ng/ml). Coronavirus disease 2019 (COVID-19) nasopharyngeal swab was performed prior to urgent coronary angiogram. Coronary angiogram was performed with full personal protective equipment for respiratory and droplet precautions due to pending COVID-19 testing results. Angiogram revealed spontaneous coronary artery dissection (SCAD) extending from the ostium of the LAD to the distal vessel. COVID-19 testing returned positive while in intensive care unit. The patient was not a percutaneous coronary intervention candidate due to the extent of the dissection and was not a surgical candidate due to a lack of graftable target and medical management was continued. To our knowledge, this case is the first in which SCAD has been reported in the LAD in a patient with COVID-19 with no other symptoms of respiratory illness or symptoms classically associated with the novel coronavirus. SCAD should be considered on the differential as one of the various cardiac manifestations of COVID-19 infection.
    MeSH term(s) COVID-19/complications ; COVID-19/diagnosis ; COVID-19/therapy ; Coronary Angiography ; Coronary Vessel Anomalies/diagnosis ; Coronary Vessel Anomalies/therapy ; Coronary Vessel Anomalies/virology ; Electrocardiography ; Female ; Humans ; Middle Aged ; Vascular Diseases/congenital ; Vascular Diseases/diagnosis ; Vascular Diseases/therapy ; Vascular Diseases/virology
    Keywords covid19
    Language English
    Publishing date 2020-05-07
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1459995-8
    ISSN 1522-726X ; 1522-1946
    ISSN (online) 1522-726X
    ISSN 1522-1946
    DOI 10.1002/ccd.28960
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  10. Article ; Online: Chest Pain and Inflammation: A Story Where Hickam's Dictum Prevailed.

    Kumar, Kris / Vogt, Joshua C / Masri, Ahmad / Golwala, Harsh / Zahr, Firas E / Divanji, Punag H / Rahmouni, Hind / Nazer, Babak

    The American journal of medicine

    2022  Volume 135, Issue 10, Page(s) e379–e384

    MeSH term(s) Chest Pain/etiology ; Humans ; Inflammation
    Language English
    Publishing date 2022-05-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80015-6
    ISSN 1555-7162 ; 1873-2178 ; 0002-9343 ; 1548-2766
    ISSN (online) 1555-7162 ; 1873-2178
    ISSN 0002-9343 ; 1548-2766
    DOI 10.1016/j.amjmed.2022.04.027
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