Artikel ; Online: Antiviral effect of multipurpose contact lens disinfecting solutions against coronavirus.
Contact lens & anterior eye : the journal of the British Contact Lens Association
2021 Band 45, Heft 5, Seite(n) 101513
Abstract: Purpose: To evaluate the antiviral potential of five multipurpose disinfecting solutions against coronavirus (mouse hepatitis virus, a surrogate for SARS-CoV-2 human corona virus).: Methods: Test solutions (Biotrue, renu Advanced [Bausch and Lomb], ... ...
Abstract | Purpose: To evaluate the antiviral potential of five multipurpose disinfecting solutions against coronavirus (mouse hepatitis virus, a surrogate for SARS-CoV-2 human corona virus). Methods: Test solutions (Biotrue, renu Advanced [Bausch and Lomb], ACUVUE RevitaLens [Johnson and Johnson Vision], cleadew [Ophtecs corp.] or AOSept Plus [Alcon]) were mixed with the coronavirus mouse hepatitis virus at 10 Results: The three multipurpose disinfecting solutions Biotrue (containing PHMB and polyquaternium-1), renu Advanced (PHMB, polyquaternium-1 and alexidine) and ACUVUE RevitaLens (polyquaternium-1 and alexidine) did not kill the coronavirus at the manufacturers recommended disinfection time in the stand alone test. After treatment, the virus's titer (3.8 ± 0.2 log Conclusions: This study shows that oxidative contact lens disinfecting solutions (i.e. those containing povidone-iodine or hydrogen peroxide) provide superior antiviral activity against a coronavirus surrogate of SARS-CoV-2, unless the full regimen test (rub, rinse, disinfect) is used. |
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Mesh-Begriff(e) | Animals ; Antiviral Agents/pharmacology ; Biguanides ; COVID-19 ; Contact Lens Solutions/pharmacology ; Contact Lenses ; Disinfectants/pharmacology ; Humans ; Hydrogen Peroxide/pharmacology ; Mice ; Phosphates ; Povidone-Iodine/pharmacology ; SARS-CoV-2 |
Chemische Substanzen | Antiviral Agents ; Biguanides ; Contact Lens Solutions ; Disinfectants ; Phosphates ; Povidone-Iodine (85H0HZU99M) ; Hydrogen Peroxide (BBX060AN9V) ; alexidine (GVN71CAL3G) |
Sprache | Englisch |
Erscheinungsdatum | 2021-08-27 |
Erscheinungsland | England |
Dokumenttyp | Journal Article |
ZDB-ID | 2004847-6 |
ISSN | 1476-5411 ; 1367-0484 |
ISSN (online) | 1476-5411 |
ISSN | 1367-0484 |
DOI | 10.1016/j.clae.2021.101513 |
Datenquelle | MEDical Literature Analysis and Retrieval System OnLINE |
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