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  1. Book ; Online: Strategies for the Synthesis of Heterocycles and Their Applications

    Kumari, Premlata / Patel, Amit B

    2023  

    Keywords Organic chemistry ; green synthesis ; water ; catalysis ; microwave ; anticancer ; green chemistry
    Language English
    Size 1 electronic resource (254 pages)
    Publisher IntechOpen
    Document type Book ; Online
    Note English
    HBZ-ID HT030381209
    ISBN 9781837682430 ; 1837682437
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article: Uterine Fibroid Treated with Homoeopathic Medicine: A Case Report

    Kumari, Punam

    Homœopathic Links

    2022  Volume 35, Issue 03, Page(s) 205–209

    Abstract: Uterine fibroids are the commonest benign uterine tumours, most commonly found in women in the reproductive age group. The cause of fibroids is not well understood. Fibroids originate from uterine smooth muscle cells whose growth is primarily dependent ... ...

    Abstract Uterine fibroids are the commonest benign uterine tumours, most commonly found in women in the reproductive age group. The cause of fibroids is not well understood. Fibroids originate from uterine smooth muscle cells whose growth is primarily dependent on the levels of circulating oestrogen. Symptoms of uterine fibroid include heavy menstrual bleeding, prolonged periods and pelvic pain. Uterine fibroid is common indication of hysterectomy nowadays and it leads to many complications. Here a case of 47-year-old woman suffering from painful menses with uterine fibroid measuring 18.4 × 17.7 mm is presented that was completely resolved with individualised homoeopathic medicine Calcarea carbonica with significant improvement in her quality of life. The case was followed up with symptomatic assessment reported by patient, Visual Analogue Scale and laboratory investigations. The case reporting is done according to the Homoeopathic clinical case reporting (HOM-CASE) guidelines, extension of Clinical case reporting (CARE) guidelines. The causal relationship between the clinical improvement and the medicine prescribed was assessed by the MONARCH Inventory, an improved version of the Modified Naranjo Criteria for Homoeopathy.
    Keywords case report ; homoeopathic medicine ; Naranjo criterion ; uterine fibroid
    Language English
    Publishing date 2022-09-01
    Publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 1199312-1
    ISSN 1860-3149 ; 1019-2050
    ISSN (online) 1860-3149
    ISSN 1019-2050
    DOI 10.1055/s-0042-1742592
    Database Thieme publisher's database

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5733: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  3. Article ; Online: Remarkable enhancement of the adsorption and diffusion performance of alkali ions in two-dimensional (2D) transition metal oxide monolayers via Ru-doping.

    Sahoo, Shubham / Kumari, P / Som, Narayan N / Kar, S / Ahuja, Rajeev / Ray, S J

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 4371

    Abstract: Transition metal oxides (TMO) are the preferred materials for metal ion battery cathodes because of their high redox potentials and good metal-ion intercalation capacity, which serve as an outstanding replacement for layered sulphide. In this work, using ...

    Abstract Transition metal oxides (TMO) are the preferred materials for metal ion battery cathodes because of their high redox potentials and good metal-ion intercalation capacity, which serve as an outstanding replacement for layered sulphide. In this work, using first-principles calculations based on Density functional theory approach, we explored the structural and electronic properties which comprise of adsorption and diffusion behaviour along with the analysis of voltage profile and storage capacity of Ru doped two-dimensional transition metal oxide [Formula: see text], [Formula: see text], and [Formula: see text] monolayers. The adsorption of alkali ions (Li, Na) to the surface of TMOs is strengthened by Ru-atom doping. Ru doping enhanced the adsorption energy of Li/Na-ion by 25%/11% for [Formula: see text], 8%/13% for [Formula: see text], and 10%/11% [Formula: see text] respectively. The open circuit voltage (OCV) also increases due to the high adsorption capacity of doped Monolayers. Ru doping makes the semiconducting TMOs conduct, which is suitable for battery application. As alkali ion moves closer to the dopant site, the adsorption energy increases. When alkali ions are close to the vicinity of doping site, their diffusion barrier decrease and rises as they go further away. Our current findings will be useful in finding ways to improve the storage performance of 2D oxide materials for application in energy harvesting and green energy architecture.
    Language English
    Publishing date 2024-02-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-53966-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Entropy-driven nonequilibrium phonon-stimulated electron-phonon coupling in tin dioxide nanorods.

    Mallik, G / Kabiraj, A / Swain, D K / Dash, P P / Kumari, P / Rath, S

    Physical review. E

    2024  Volume 109, Issue 2-1, Page(s) 24213

    Abstract: Nonequilibrium (NEQ) phonon fluctuation in a nanosystem has been studied through the statistical assessment of the entropy-production and -consumption events in ultrasmall tin dioxide (SnO_{2}) nanorods. Size- and shape-dependent alteration in free ... ...

    Abstract Nonequilibrium (NEQ) phonon fluctuation in a nanosystem has been studied through the statistical assessment of the entropy-production and -consumption events in ultrasmall tin dioxide (SnO_{2}) nanorods. Size- and shape-dependent alteration in free energy leading to modulation of the probability distribution function of the phonon dynamics has been observed from the x-ray diffraction and Raman scattering characterizations. The Gallavotti-Cohen nonequilibrium fluctuation theorem has been utilized to qualitatively describe the aforementioned behaviors under the influence of a global flux. The observation of entropy consumption and thermodynamically favorable entropy-production events indicates the presence of NEQ fluctuations in the phonon modes. The effective energy scale of fluctuation in driven phonon modes, dissipating energy faster than relaxation time, is quantified on the order of nanojoules. From optical absorption and photoluminescence studies, the observation of the electron-phonon coupled state confirms the interaction of the NEQ phonons with electrons. The strength of the coupling has been estimated from the temperature-independent Barry center shift and found to be enhanced to 5.35. Valence band x-ray photoelectron spectroscopy and Fourier transformed infrared spectroscopy analyses reconcile NEQ phonon mediated alteration of the valence band density of states, activation of silent phonon modes, and superior excitonic transitions, suitable for the new generation of ultrafast quantum device applications.
    Language English
    Publishing date 2024-03-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2844562-4
    ISSN 2470-0053 ; 2470-0045
    ISSN (online) 2470-0053
    ISSN 2470-0045
    DOI 10.1103/PhysRevE.109.024213
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Assessment of mould remediation in a healthcare setting following extensive flooding.

    Meda, M / Gentry, V / Preece, E / Nagy, C / Kumari, P / Wilson, P / Hoffman, P

    The Journal of hospital infection

    2024  Volume 146, Page(s) 1–9

    Abstract: Background: A new hospital building was close to completion when a large pipe carrying clean water broke, causing extensive flooding.: Aim: To determine the flood-associated fungal risk to susceptible patients who would use that building.: Methods!# ...

    Abstract Background: A new hospital building was close to completion when a large pipe carrying clean water broke, causing extensive flooding.
    Aim: To determine the flood-associated fungal risk to susceptible patients who would use that building.
    Methods: Though standard flood remediation by the builders was relatively straightforward, there was no model for specialist assessment of patient risk due to the flood-associated mould growth. As levels of background airborne fungal spores can be expected to vary significantly over time, we could not use absolute levels to indicate either an excess of airborne fungal spores or successful remediation. Therefore it was decided to use weekly settle plates, exposed at the same time in flooded (test) and equivalent non-flooded (control) areas to compensate for variations in background levels. Flood-related risk was estimated by the ratio between fungal colonies on the test and control sets of settle plates, rather than absolute number.
    Findings: Whereas the physical flood remediation, including the use of 'anti-fungal' treatments, was completed in three weeks post flooding, fungal contamination in flooded areas took 38 weeks to return to control levels and remained so for a further six weeks of observation.
    Conclusion: By the use of this method, we were able to assure the absence of flood-associated fungal risk to susceptible patients who would use that building. We recommend that infection prevention and control teams consider using this approach should they be faced with similar situations.
    MeSH term(s) Humans ; Floods ; Fungi ; Spores, Fungal ; Risk ; Delivery of Health Care
    Language English
    Publishing date 2024-01-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 779366-2
    ISSN 1532-2939 ; 0195-6701
    ISSN (online) 1532-2939
    ISSN 0195-6701
    DOI 10.1016/j.jhin.2023.11.024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1586: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Birth and death view of DNA, RNA, and proteins.

    Kumari, Pooja / Sarovar Bhavesh, Neel

    Gene

    2023  Volume 883, Page(s) 147672

    Abstract: The potential of cells to guide their genome and configure genes to express at a given time and in response to specific stimuli is pivotal to regulate cellular processes such as tissue differentiation, organogenesis, organismal development, homeostasis, ... ...

    Abstract The potential of cells to guide their genome and configure genes to express at a given time and in response to specific stimuli is pivotal to regulate cellular processes such as tissue differentiation, organogenesis, organismal development, homeostasis, and disease. In this review, we focus on the diverse mechanisms involved in DNA replication and its degradation, mRNA synthesis, and associated regulation such as RNA capping, splicing, tailing, and export. mRNA turnover including Decapping, deadenylation, RNA interference, and Nonsense mediated mRNA decay followed by protein translation, post-translational modification, and protein turnover. We highlight recent advances in understanding the complex series of molecular mechanisms responsible for the remarkable cellular regulatory mechanisms.
    MeSH term(s) Proteins/genetics ; Proteins/metabolism ; DNA/genetics ; DNA/metabolism ; RNA/genetics ; RNA/metabolism ; Protein Biosynthesis ; Transcription, Genetic ; RNA Splicing ; RNA Stability
    Chemical Substances Proteins ; DNA (9007-49-2) ; RNA (63231-63-0)
    Language English
    Publishing date 2023-07-26
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 391792-7
    ISSN 1879-0038 ; 0378-1119
    ISSN (online) 1879-0038
    ISSN 0378-1119
    DOI 10.1016/j.gene.2023.147672
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1357: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Sources and toxicological effects of metal and metalloids on human health through fish consumption in mineral-rich city, Ranchi, India.

    Kumari, Preeti / Hansdah, Puja

    Environmental monitoring and assessment

    2023  Volume 195, Issue 9, Page(s) 1032

    Abstract: Ranchi is the administrative capital of Jharkhand and is located in the southern part of the Chhotanagpur Plateau. It is rich in forest and mineral resources and hence is suitable for the establishment of many large- and small-scale industries. The ... ...

    Abstract Ranchi is the administrative capital of Jharkhand and is located in the southern part of the Chhotanagpur Plateau. It is rich in forest and mineral resources and hence is suitable for the establishment of many large- and small-scale industries. The estimated population of Ranchi for the year 2023 is 3.54 million. These demographic characteristics make the capital more vulnerable to environmental degradation. Also, previous water quality research focused on river, water, and oceans separately; however, little or no work has been carried out on the comparison of metal or metalloid analysis in rivers, waterfalls, and lakes. Hence, the present study aims to assess the pollution status of mineral-rich and industrial hub city, Ranchi, through analysis of metals or metalloids in abiotic (water and sediment) and biotic (fish and human) components. The water, sediment, and fish (Labeo rohita and Catla catla) samples were collected from Subarnarekha river, Jumar river, Dassam fall, Getalsud dam, Hundru fall, Jonha fall, Kanke dam, and Sita fall. Samples were collected following standard methods and analyzed in inductively coupled plasma mass spectrometry (ICP-MS). Among three aquatic systems (rivers, dams, and falls), dams were highly polluted with metals or metalloids, which may be due to effluent discharge from different industries. Additionally, the high population in the city also contributed to metals or metalloids pollution. The reason may be the direct sewage disposal and agricultural and surface runoff in the water systems. It was observed that most of the aquatic systems in Ranchi were severely polluted with metals or metalloids. The fish also accumulated these metals or metalloids in their body and can be life-threatening to the human population consuming them. The THQ (above 1) and HI (2.95) values for As showed that children are more vulnerable to health risk through consumption of contaminated fish. Hence, proper planning and management are needed to overcome the metals or metalloids pollution in Ranchi.
    MeSH term(s) Animals ; Child ; Humans ; Metalloids/toxicity ; Metalloids/analysis ; Water Pollutants, Chemical/toxicity ; Water Pollutants, Chemical/analysis ; Environmental Monitoring/methods ; Metals/toxicity ; Metals/analysis ; Water Quality ; Cyprinidae ; Minerals/analysis ; Rivers/chemistry ; Metals, Heavy/toxicity ; Metals, Heavy/analysis ; Risk Assessment/methods
    Chemical Substances Metalloids ; Water Pollutants, Chemical ; Metals ; Minerals ; Metals, Heavy
    Language English
    Publishing date 2023-08-10
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 782621-7
    ISSN 1573-2959 ; 0167-6369
    ISSN (online) 1573-2959
    ISSN 0167-6369
    DOI 10.1007/s10661-023-11639-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 5186: Show issues

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  8. Article ; Online: Mechanical Alloying in Zeolitic Imidazolate Framework for Enhanced Photocatalytic Dye Degradation.

    Kumari, Priyanka / Panda, Tamas

    Inorganic chemistry

    2023  Volume 62, Issue 38, Page(s) 15335–15339

    Abstract: A ball milling approach has been performed for isostructural ZnZIF-8 and CoZIF-8 in a 1:1 molar ratio to produce the amorphous ( ...

    Abstract A ball milling approach has been performed for isostructural ZnZIF-8 and CoZIF-8 in a 1:1 molar ratio to produce the amorphous (
    Language English
    Publishing date 2023-09-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1484438-2
    ISSN 1520-510X ; 0020-1669
    ISSN (online) 1520-510X
    ISSN 0020-1669
    DOI 10.1021/acs.inorgchem.3c01688
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: One shot learning approach for cross spectrum periocular verification.

    Kumari, Punam / Seeja, K R

    Multimedia tools and applications

    2023  Volume 82, Issue 13, Page(s) 20589–20604

    Abstract: The use of face mask during the COVID-19 pandemic has increased the popularity of the periocular biometrics in surveillance applications. Despite of the rapid advancements in this area, matching images over cross spectrum is still a challenging problem. ... ...

    Abstract The use of face mask during the COVID-19 pandemic has increased the popularity of the periocular biometrics in surveillance applications. Despite of the rapid advancements in this area, matching images over cross spectrum is still a challenging problem. Reason may be two-fold 1) variations in image illumination 2) small size of available data sets and/or class imbalance problem. This paper proposes Siamese architecture based convolutional neural networks which works on the concept of one-shot classification. In one shot classification, network requires a single training example from each class to train the complete model which may lead to reduce the need of large dataset as well as doesn't matter whether the dataset is imbalance. The proposed architectures comprise of identical subnetworks with shared weights whose performance is assessed on three publicly available databases namely IMP, UTIRIS and PolyU with four different loss functions namely Binary cross entropy loss, Hinge loss, contrastive loss and Triplet loss. In order to mitigate the inherent illumination variations of cross spectrum images CLAHE was used to preprocess images. Extensive experiments show that the proposed Siamese CNN model with triplet loss function outperforms the states of the art periocular verification methods for cross, mono and multi spectral periocular image matching.
    Language English
    Publishing date 2023-01-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1479928-5
    ISSN 1573-7721 ; 1380-7501
    ISSN (online) 1573-7721
    ISSN 1380-7501
    DOI 10.1007/s11042-023-14386-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Evaluation of Enhanced Cytotoxicity Effect of Repurposed Drug Simvastatin/ Thymoquinone Combination against Breast Cancer Cell Line.

    Kumari, Pallavi / Dang, Shweta

    Cardiovascular & hematological agents in medicinal chemistry

    2023  

    Abstract: Introduction: The repurposing of drugs for their anticancer potential is gaining a lot of importance in drug discovery.: Aims: The present study aims to explore the potential of Simvastatin (SIM), a drug used in the treatment of high cholesterol, and ...

    Abstract Introduction: The repurposing of drugs for their anticancer potential is gaining a lot of importance in drug discovery.
    Aims: The present study aims to explore the potential of Simvastatin (SIM), a drug used in the treatment of high cholesterol, and thymoquinone (Nigella Sativa) (THY) for its anti-cancer activity on breast cancer cell lines. Thymoquinone is reported to have many potential medicinal properties exhibiting antioxidant, antiinflammatory, anti-cancer, and activities like tissue growth and division, hormone regulation, immune response and development, and cell signaling.
    Methods: In this analysis, we explored the inhibitory effects of the combination of simvastatin ad thymoquinone on two breast cancer cell lines viz MCF-7 and MDA-MB-231 cells. The combined effect of simvastatin ad thymoquinone on cell viability, colony formation, cell migration, and orientation of more programmed cell death in vitro was studied. Cell cycle arrest in the G2/M phase was concomitant with the combined effect of SIM and THY persuading apoptosis and generating reactive oxygen species (ROS).
    Results: The cell cycle arrest in combined treatment was 8.1% on MCF-7 cells and 3.8 % for MDA-MB-231 cells an increased apoptosis was observed when cells were treated in combination which was about 76.20% and 58.15 % respectively for MCF-7 and MDA-MB-231 cells.
    Conclusion: It was concluded that the combined effect of simvastatin and thymoquinone stimulates apoptosis in breast cancer cells.
    Language English
    Publishing date 2023-10-27
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2215710-4
    ISSN 1875-6182 ; 1871-5257
    ISSN (online) 1875-6182
    ISSN 1871-5257
    DOI 10.2174/0118715257259037231012182741
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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