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Article: Physiologic and pharmacologic considerations in morbid obesity and bariatric anesthesia.

Brondeel, Kimberley C / Lakatta, Alexis C / Torres, Grant B / Hurley, Joshua J / Kunik, Illan L / Haney, Kaley F / Cornett, Elyse M / Kaye, Alan D

Saudi journal of anaesthesia

2022  Volume 16, Issue 3, Page(s) 306–313

Abstract: Obesity is a growing worldwide health hazard that is characterized by excess malnutrition. Excess food intake leads to dysregulated energy homeostasis and increased adiposity, activating pro-inflammatory physiologic pathways that can contribute to the ... ...

Abstract Obesity is a growing worldwide health hazard that is characterized by excess malnutrition. Excess food intake leads to dysregulated energy homeostasis and increased adiposity, activating pro-inflammatory physiologic pathways that can contribute to the chronic inflammatory state associated with many chronic illnesses. Obesity is a preventable illness, but its multifaceted etiology, including genetic, behavioral, and environmental variables, is critical to understanding its epidemiology and pathophysiology. Obesity is a critical predisposing factor for illnesses including type II diabetes, cardiovascular disease, and cancer, with higher morbidity and death. Obesity rates are rising, and so will the need for perioperative anesthesia for subjects with obesity. Obesity epidemiology, biochemistry, and pathophysiology are significant concepts in perioperative anesthesia management for subjects with obesity. To provide optimal intraoperative care for subjects with obesity, preoperative cardiovascular assessment for coronary artery disease and drug monitoring is required. Individuals suffering from obesity have significantly higher oxygen consumption rates and a higher risk of desaturation and surgical complications. Individuals suffering from obesity require specialized perioperative treatment related to higher prevalence of perioperative complications.
Language English
Publishing date 2022-06-20
Publishing country India
Document type Journal Article ; Review
ZDB-ID 2562174-9
ISSN 0975-3125 ; 1658-354X
ISSN (online) 0975-3125
ISSN 1658-354X
DOI 10.4103/sja.sja_185_22
Database MEDical Literature Analysis and Retrieval System OnLINE

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