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  1. AU="Kunze, Susanne"
  2. AU="Haugen Bryan R"
  3. AU="Bartsch, Lea M"
  4. AU="Vendredy, Leen"
  5. AU="Mang-Mang Chen"

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  1. Book ; Thesis: Untersuchungen zur Glukoseaufnahme in Granulozyten bei Sepsis und CAPD

    Kunze, Susanne

    1993  

    Author's details vorgelegt von Susanne Kunze
    Language German
    Size 1 Mikrofiche
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Freiburg (Breisgau), Univ., Diss., 1993
    Note Manuskript: III, 59 Bl. : graph. Darst.
    HBZ-ID HT006235395
    Database Catalogue ZB MED Medicine, Health

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  2. Book ; Online ; Thesis: In-vitro-Untersuchungen zur Zellverträglichkeit und antikoagulierenden Wirkung von carboxymethylierten und nicht carboxymethylierten sulfatierten Hyaluronsäuren und natürlichen Huminsäuren

    Kunze, Susanne

    2007  

    Author's details von Susanne Kunze, geb. Keßler
    Language German
    Size Online-Ressource
    Document type Book ; Online ; Thesis
    Thesis / German Habilitation thesis Univ., Diss--Halle (Saale), 2007
    Database Former special subject collection: coastal and deep sea fishing

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  3. Book ; Online ; Thesis: In-vitro-Untersuchungen zur Zellverträglichkeit und antikoagulierenden Wirkung von carboxymethylierten und nicht carboxymethylierten sulfatierten Hyaluronsäuren und natürlichen Huminsäuren

    Kunze, Susanne

    2007  

    Abstract: Zsfassung in engl. ... ...

    Author's details von Susanne Kunze
    Abstract Zsfassung in engl. Sprache
    Language German
    Size Online-Ressource, Text + Image (kB)
    Publisher Universitäts- und Landesbibliothek Sachsen-Anhalt
    Publishing place Halle, Saale
    Document type Book ; Online ; Thesis
    Thesis / German Habilitation thesis Univ., Nat. Fak. I, Diss.--Halle, 2007
    Database Former special subject collection: coastal and deep sea fishing

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  4. Book ; Online ; Thesis: In-vitro-Untersuchungen zur Zellverträglichkeit und antikoagulierenden Wirkung von carboxymethylierten und nicht carboxymethylierten sulfatierten Hyaluronsäuren und natürlichen Huminsäuren

    Kunze, Susanne [Verfasser]

    2007  

    Author's details von Susanne Kunze, geb. Keßler
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  5. Article ; Online: Association of CMV-specific T-cell immunity and risk of CMV infection in lung transplant recipients.

    Veit, Tobias / Pan, Ming / Munker, Dieter / Arnold, Paola / Dick, Andrea / Kunze, Susanne / Meiser, Bruno / Schneider, Christian / Michel, Sebastian / Zoller, Michael / Böhm, Stephan / Walter, Julia / Behr, Jürgen / Kneidinger, Nikolaus / Kauke, Teresa

    Clinical transplantation

    2021  Volume 35, Issue 6, Page(s) e14294

    Abstract: Background: Protecting against CMV infection and maintaining CMV in latent state are largely provided by CMV-specific T-cells in lung transplant recipients. The aim of the study was to assess whether a specific T-cell response is associated with the ... ...

    Abstract Background: Protecting against CMV infection and maintaining CMV in latent state are largely provided by CMV-specific T-cells in lung transplant recipients. The aim of the study was to assess whether a specific T-cell response is associated with the risk for CMV infection in seronegative patients who are at high risk for delayed CMV infection.
    Methods: All CMV-seronegative recipients (R-) from CMV-seropositive donors (D+) between January 2018 and April 2019 were included and retrospectively screened for CMV infection before and after assessment of CMV-specific cell-mediated immunity.
    Results: Thirty-one of the 50 patients (62%) developed early-onset CMV infection. Lower absolute neutrophil counts were significantly associated with early-onset CMV infection. Antiviral prophylaxis was ceased after 137.2 ± 42.8 days. CMV-CMI were measured at a median of 5.5 months after LTx. 19 patients experienced early and late-onset CMV infection after prophylaxis withdrawal within 15 months post transplantation. Positive CMV-CMI was significantly associated with lower risk of late-onset CMV infection after transplantation in logistic and cox-regression analysis (OR=0.05, p = .01; OR=2,369, p = .026).
    Conclusion: D+/R- lung transplant recipients are at high risk of developing early and late-onset CMV infection. Measurement of CMV-CMI soon after transplantation might further define the CMV infection prediction risk in LTx recipients being at high risk for CMV viremia.
    MeSH term(s) Antiviral Agents/therapeutic use ; Cytomegalovirus ; Cytomegalovirus Infections/drug therapy ; Cytomegalovirus Infections/epidemiology ; Cytomegalovirus Infections/etiology ; Humans ; Lung ; Retrospective Studies ; T-Lymphocytes ; Transplant Recipients
    Chemical Substances Antiviral Agents
    Language English
    Publishing date 2021-04-03
    Publishing country Denmark
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 639001-8
    ISSN 1399-0012 ; 0902-0063
    ISSN (online) 1399-0012
    ISSN 0902-0063
    DOI 10.1111/ctr.14294
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Correction

    Shabani Naim / Bruning Ansgar / Mylonas Ioannis / Kunze Susanne / Kupka Markus S

    Reproductive Biology and Endocrinology, Vol 9, Iss 1, p

    Evidence of inhibin/activin subunit betaC and betaE synthesis in normal human endometrial tissue

    2011  Volume 1

    Keywords Physiology ; QP1-981 ; Science ; Q ; DOAJ:Physiology ; DOAJ:Biology ; DOAJ:Biology and Life Sciences
    Language English
    Publishing date 2011-01-01T00:00:00Z
    Publisher BioMed Central
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Evidence of inhibin/activin subunit betaC and betaE synthesis in normal human endometrial tissue

    Shabani Naim / Brüning Ansgar / Mylonas Ioannis / Kunze Susanne / Kupka Markus S

    Reproductive Biology and Endocrinology, Vol 8, Iss 1, p

    2010  Volume 143

    Abstract: Abstract Background Inhibins are important regulators of the female reproductive system. Recently, two new inhibin subunits betaC and betaE have been described, although it is unclear if they are synthesized in normal human endometrium. Methods Samples ... ...

    Abstract Abstract Background Inhibins are important regulators of the female reproductive system. Recently, two new inhibin subunits betaC and betaE have been described, although it is unclear if they are synthesized in normal human endometrium. Methods Samples of human endometrium were obtained from 82 premenopausal, non-pregnant patients undergoing gynecological surgery for benign diseases. Endometrium samples were classified according to anamnestic and histological dating into proliferative (day 1-14, n = 46), early secretory (day 15-22, n = 18) and late secretory phase (day 23-28, n = 18). Immunohistochemical analyses were performed with specific antibodies against inhibin alpha (n = 81) as well as inhibin betaA (n = 82), betaB (n = 82), betaC (n = 74) and betaE (n = 76) subunits. RT-PCR was performed for all inhibin subunits. Correlation was assessed with the Spearman factor to assess the relationship of inhibin-subunits expression within the different endometrial samples. Results The novel inhibin betaC and betaE subunits were found in normal human endometrium by immunohistochemical and molecular techniques. Inhibin alpha, betaA, betaB and betaE subunits showed a circadian expression pattern, being more abundant during the late secretory phase than during the proliferative phase. Additionally, a significant correlation between inhibin alpha and all inhibin beta subunits was observed. Conclusions The differential expression pattern of the betaC- and betaE-subunits in normal human endometrial tissue suggests that they function in endometrial maturation and blastocyst implantation. However, the precise role of these novel inhibin/activin subunits in human endometrium is unclear and warrants further investigation.
    Keywords Physiology ; QP1-981 ; Science ; Q ; DOAJ:Physiology ; DOAJ:Biology ; DOAJ:Biology and Life Sciences
    Subject code 610
    Language English
    Publishing date 2010-11-01T00:00:00Z
    Publisher BioMed Central
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Book ; Thesis: Untersuchungen zur Glukoseaufnahme in Granulozyten bei Sepsis und CAPD

    Kunze, Susanne

    1993  

    Author's details vorgelegt von Susanne Kunze
    Language Undetermined
    Size 1 Mikrofiche
    Document type Book ; Thesis
    Thesis / German Habilitation thesis @Freiburg (Breisgau), Univ., Diss. : 1993
    Note Mikroreprod. e. Ms. III, 59 Bl. : graph. Darst.
    Database Former special subject collection: coastal and deep sea fishing

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  9. Article ; Online: Correction: Evidence of inhibin/activin subunit betaC and betaE synthesis in normal human endometrial tissue.

    Mylonas, Ioannis / Bruning, Ansgar / Shabani, Naim / Kunze, Susanne / Kupka, Markus S

    Reproductive biology and endocrinology : RB ; & ; E

    2011  Volume 9, Issue 1, Page(s) 1

    Language English
    Publishing date 2011
    Publishing country England
    Document type Journal Article
    ISSN 1477-7827
    ISSN (online) 1477-7827
    DOI 10.1186/1477-7827-9-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Inhibin-betaC subunit expression in normal and pathological human placental tissues.

    Mylonas, Ioannis / Makovitzky, Josef / Kunze, Susanne / Brüning, Ansgar / Kainer, Franz / Schiessl, Barbara

    Systems biology in reproductive medicine

    2011  Volume 57, Issue 4, Page(s) 197–203

    Abstract: Inhibins and activins are important regulators of the female reproductive system. Recently, a novel inhibin betaC subunit has been identified. However, only limited data on the expression of this novel inhibin-betaC subunit in normal and pathological ... ...

    Abstract Inhibins and activins are important regulators of the female reproductive system. Recently, a novel inhibin betaC subunit has been identified. However, only limited data on the expression of this novel inhibin-betaC subunit in normal and pathological human placentas exist. Tissue specimens of normal, preeclamptic, hemolysis, elevated liver enzymes, low platelets (HELLP), and intrauterine growth restriction (IUGR) pregnancies (n=24) were obtained at the conclusion of a cesarean section. Normal and pathological placental tissues were analyzed by an immunohistochemical staining reaction with a specific antibody against this novel inhibin-betaC subunit. Overall, expression of the inhibin-betaC subunit could be demonstrated in normal and pathological placental tissue. The immunoreactive score (IRS) for inhibin-betaC did not show any significant differences between normal, preeclamptic, HELLP, and IUGR tissue in extravillous trophoblast and syncytiotrophoblast cells. Immunolabelling of this novel inhibin-βC protein in normal and pathological placental tissue was demonstrated, although no differences in the staining intensity could be observed. Therefore, the inhibin-βC isoform might not primarily be involved in the pathogenesis of these pregnancy-associated disorders. The functional role of this novel inhibin-betaC subunit in normal and pathological human placenta is still quite unclear and should thus be further investigated.
    MeSH term(s) Female ; Fetal Growth Retardation/metabolism ; HELLP Syndrome/metabolism ; Humans ; Immunohistochemistry ; Inhibin-beta Subunits/biosynthesis ; Placenta/metabolism ; Placenta/pathology ; Pre-Eclampsia/metabolism ; Pregnancy ; Pregnancy Complications/metabolism
    Chemical Substances Inhibin-beta Subunits (93443-12-0)
    Language English
    Publishing date 2011-08
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2417234-0
    ISSN 1939-6376 ; 1939-6368
    ISSN (online) 1939-6376
    ISSN 1939-6368
    DOI 10.3109/19396368.2010.528505
    Database MEDical Literature Analysis and Retrieval System OnLINE

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