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  1. Article: Gestational hemostasis: a natural model for hemostasis resuscitation of major periprocedural blood loss : "Look deep into nature, and then you will understand everything better." Albert Einstein.

    Babik, Barna / Kupcsulik, Szilvia / Fazakas, János

    Perioperative medicine (London, England)

    2021  Volume 10, Issue 1, Page(s) 54

    Abstract: Early goal-directed treatment is an evidence-based approach to guide hemostatic therapy during major periprocedural bleeding. If viscoelastic coagulation tests are not available, an algorithm, termed the pyramid of hemostatic interventions, can help ... ...

    Abstract Early goal-directed treatment is an evidence-based approach to guide hemostatic therapy during major periprocedural bleeding. If viscoelastic coagulation tests are not available, an algorithm, termed the pyramid of hemostatic interventions, can help manage severe bleeding. Pregnant women accumulate huge reserves of prothrombotic and antifibrinolytic hemostatic elements to avoid peripartum blood loss. We provide comparison of therapeutic hemostatic approaches and natural gestational process and identified remarkable analogy between early goal-directed management of bleeding and hemostatic adaptation of pregnant woman. Therefore, gestational hemostasis serves as a natural model for goal-directed hemostasis resuscitation and can foster understanding of hemostatic management of periprocedural bleeding.
    Language English
    Publishing date 2021-12-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 2683800-X
    ISSN 2047-0525
    ISSN 2047-0525
    DOI 10.1186/s13741-021-00225-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Importance of the imaging techniques in the management of COVID-19-infected patients

    Lovas, András / Hankovszky, Péter / Korsós, Anita / Kupcsulik, Szilvia / Molnár, Tamás / Szabó, Zsolt / Babik, Barna

    Orvosi hetilap

    2020  Volume 161, Issue 17, Page(s) 672–677

    Abstract: Critical-care physicians are facing a challenging process in healthcare due to the overwhelming case number of hypoxic respiratory failure patients. Pneumonia has an utmost importance in the primary pathomechanism of the development of critical illness ... ...

    Title translation [A képalkotó diagnosztika jelentősége a COVID–19-fertőzött betegek ellátásában]
    Abstract Critical-care physicians are facing a challenging process in healthcare due to the overwhelming case number of hypoxic respiratory failure patients. Pneumonia has an utmost importance in the primary pathomechanism of the development of critical illness in the COVID-19 patients. Thus, imaging techniques are situated in the frontline to aim the diagnostic decision-making, to follow up the progress and to evaluate the possible complications. Reviewing the available literature, so far the common chest CT, chest X-ray and chest wall ultrasound features are presented, and recommendations are pronounced for the indications of the different modalities. At the initial phase, the atypical presentations of the virus infection are multiplex, peripheral ground glass opacities situated in the right lower lobe of the lung evolving rapidly into a bilateral involvement of the middle and basal zones. Along with the progression, the ratio of the consolidation is increasing subsequently deteriorating into fibrosis with reticular pattern. Chest ultrasound performed at the bedside has a paramount importance to reduce the possible number of health-care worker contacts in consequence of the strict and special infection control orders established on account of the SARS-CoV-2 pandemia. Orv Hetil. 2020; 161(17): 672–677.
    MeSH term(s) Betacoronavirus ; COVID-19 ; COVID-19 Testing ; Clinical Laboratory Techniques ; Coronavirus Infections/diagnosis ; Coronavirus Infections/diagnostic imaging ; Disease Progression ; Humans ; Pandemics ; Pneumonia, Viral/diagnostic imaging ; Point-of-Care Systems ; Radiography, Thoracic ; SARS-CoV-2 ; Tomography, X-Ray Computed ; Ultrasonography
    Keywords covid19
    Language Hungarian
    Publishing date 2020-04-01
    Publishing country Hungary
    Document type Journal Article ; Review
    ZDB-ID 123879-6
    ISSN 1788-6120 ; 0030-6002
    ISSN (online) 1788-6120
    ISSN 0030-6002
    DOI 10.1556/650.2020.31814
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Diagnostic consideration and bedside estimation of the prognosis in COVID-19 patients

    Korsós, Anita / Kupcsulik, Szilvia / Lovas, András / Hankovszky, Péter / Molnár, Tamás / Szabó, Zsolt / Babik, Barna

    Orvosi hetilap

    2020  Volume 161, Issue 17, Page(s) 667–671

    Abstract: In December 2019, a cluster of pneumonia cases of unknown origin occured in Wuhan, China. The identified infective agent is a novel corona virus called “severe acute respiratory syndrome coronavirus 2” (SARS-CoV-2) and the respiratory disease caused by ... ...

    Title translation [Diagnosztikus lépések és a betegség prognózisának becslése COVID–19-fertőzött betegeken]
    Abstract In December 2019, a cluster of pneumonia cases of unknown origin occured in Wuhan, China. The identified infective agent is a novel corona virus called “severe acute respiratory syndrome coronavirus 2” (SARS-CoV-2) and the respiratory disease caused by this agent aquired the name “coronavirus disease 2019” (COVID-19). In March 2020, the World Health Organization (WHO) declared the novel coronavirus outbreak a pandemic. We reviewed the international literature regarding the novel coronavirus outbreak. Here below, we focus mainly on the diagnostic issues of COVID-19 and on the estimation of the prognosis. We detail the relevant anamnestic factors and initial examination results which serve as basics for the clinical suspicion of COVID-19. We also focus on the proper method of microbiological sampling and the relevant informations regarding diagnostic tests like the gold standard real-time reverse transcriptase polymerase chain reaction (RT-PCR) for SARS-CoV-2. We also cite the current national epidemiologic regulations of testing for novel coronavirus. In the last section, we emphasize the importance and the potential way of early identification of high-risk patients. The COVID-19 pandemic may cause substantial epidemiological and healthcare burden even in Hungary. In addition to the epidemiologic interventions aiming the deceleration of the outbreak, the early identification and the correct hospital treatment remain key issues since these may influence mortality. The chances of the critically ill patients could be improved solely by a high-quality and careful critical care. It is prudent to meet the experiences of colleagues working hard with these patients in the already heavily infected countries. Orv Hetil. 2020; 161(17): 667–671.
    MeSH term(s) Betacoronavirus/genetics ; Betacoronavirus/isolation & purification ; COVID-19 ; COVID-19 Testing ; COVID-19 Vaccines ; China ; Clinical Laboratory Techniques ; Coronavirus Infections/diagnosis ; Critical Illness ; Humans ; Hungary ; Pandemics ; Pneumonia, Viral/diagnosis ; Prognosis ; Real-Time Polymerase Chain Reaction ; Risk Assessment ; SARS-CoV-2
    Chemical Substances COVID-19 Vaccines ; Covid-19 aAPC vaccine
    Keywords covid19
    Language Hungarian
    Publishing date 2020-04-01
    Publishing country Hungary
    Document type Journal Article ; Review
    ZDB-ID 123879-6
    ISSN 1788-6120 ; 0030-6002
    ISSN (online) 1788-6120
    ISSN 0030-6002
    DOI 10.1556/650.2020.31815
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: [A képalkotó diagnosztika jelentosége a COVID­19-fertozött betegek ellátásában]/ Importance of the imaging techniques in the management of COVID-19-infected patients

    Lovas, András / Hankovszky, Péter / Korsós, Anita / Kupcsulik, Szilvia / Molnár, Tamás / Szabó, Zsolt / Babik, Barna

    Orv Hetil

    Abstract: Critical-care physicians are facing a challenging process in healthcare due to the overwhelming case number of hypoxic respiratory failure patients. Pneumonia has an utmost importance in the primary pathomechanism of the development of critical illness ... ...

    Abstract Critical-care physicians are facing a challenging process in healthcare due to the overwhelming case number of hypoxic respiratory failure patients. Pneumonia has an utmost importance in the primary pathomechanism of the development of critical illness in the COVID-19 patients. Thus, imaging techniques are situated in the frontline to aim the diagnostic decision-making, to follow up the progress and to evaluate the possible complications. Reviewing the available literature, so far the common chest CT, chest X-ray and chest wall ultrasound features are presented, and recommendations are pronounced for the indications of the different modalities. At the initial phase, the atypical presentations of the virus infection are multiplex, peripheral ground glass opacities situated in the right lower lobe of the lung evolving rapidly into a bilateral involvement of the middle and basal zones. Along with the progression, the ratio of the consolidation is increasing subsequently deteriorating into fibrosis with reticular pattern. Chest ultrasound performed at the bedside has a paramount importance to reduce the possible number of health-care worker contacts in consequence of the strict and special infection control orders established on account of the SARS-CoV-2 pandemia. Orv Hetil. 2020; 161(17): 672­677.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #32324360
    Database COVID19

    Kategorien

  5. Article: [Diagnostic steps and estimation of disease prognosis in COVID-19-infected patients]

    Korsos, Anita / Kupcsulik, Szilvia / Lovas, Andras / Hankovszky, Peter / Molnar, Tamas / Szabo, Zsolt / Babik, Barna

    Orv Hetil

    Abstract: In December 2019, a new coronavirus outbreak hit his head in Wuhan, China The identified pathogen is a new coronavirus named "severe acute respiratory syndrome coronavirus 2," or SARS-CoV-2, and the respiratory syndrome it elicits was named "coronavirus ... ...

    Abstract In December 2019, a new coronavirus outbreak hit his head in Wuhan, China The identified pathogen is a new coronavirus named "severe acute respiratory syndrome coronavirus 2," or SARS-CoV-2, and the respiratory syndrome it elicits was named "coronavirus disease 2019," or COVID-19 The World Health Organization (WHO) classified the epidemic as a pandemic in March 2020 We reviewed the currently available international literature on the COVID-19 epidemic In this paper, we summarize the relevant information for the diagnosis and prognosis of the new coronavirus Details of the anamnestic factors and initial test results required to raise a clinical suspicion, the method of microbiological sampling, the basic information on the molecular diagnostic test - the 'gold-standard' real-time 'reverse transcriptase polymerase chain reaction (RT-PCR) - in particular the diagnostic current public health regulations for testing We also place emphasis on the parameters of high-risk patients and how to identify them The COVID-19 pandemic may also have significant epidemiological and health consequences in Hungary In addition to epidemiological measures to slow down the epidemic, the timely identification and adequate hospital care of already infected individuals is also a key issue in terms of mortality The chances of critically ill patients can only be improved with high-quality, careful intensive care, and to be able to provide the best, it is useful to use the experience of medical colleagues already working in endemic countries Orv Hetil 2020;160 (17): 667-671
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #121181
    Database COVID19

    Kategorien

  6. Article: [Diagnosztikus lépések és a betegség prognózisának becslése COVID­19-fertozött betegeken]/ Diagnostic consideration and bedside estimation of the prognosis in COVID-19 patients

    Korsós, Anita / Kupcsulik, Szilvia / Lovas, András / Hankovszky, Péter / Molnár, Tamás / Szabó, Zsolt / Babik, Barna

    Orv Hetil

    Abstract: In December 2019, a cluster of pneumonia cases of unknown origin occured in Wuhan, China. The identified infective agent is a novel corona virus called "severe acute respiratory syndrome coronavirus 2" (SARS-CoV-2) and the respiratory disease caused by ... ...

    Abstract In December 2019, a cluster of pneumonia cases of unknown origin occured in Wuhan, China. The identified infective agent is a novel corona virus called "severe acute respiratory syndrome coronavirus 2" (SARS-CoV-2) and the respiratory disease caused by this agent aquired the name "coronavirus disease 2019" (COVID-19). In March 2020, the World Health Organization (WHO) declared the novel coronavirus outbreak a pandemic. We reviewed the international literature regarding the novel coronavirus outbreak. Here below, we focus mainly on the diagnostic issues of COVID-19 and on the estimation of the prognosis. We detail the relevant anamnestic factors and initial examination results which serve as basics for the clinical suspicion of COVID-19. We also focus on the proper method of microbiological sampling and the relevant informations regarding diagnostic tests like the gold standard real-time reverse transcriptase polymerase chain reaction (RT-PCR) for SARS-CoV-2. We also cite the current national epidemiologic regulations of testing for novel coronavirus. In the last section, we emphasize the importance and the potential way of early identification of high-risk patients. The COVID-19 pandemic may cause substantial epidemiological and healthcare burden even in Hungary. In addition to the epidemiologic interventions aiming the deceleration of the outbreak, the early identification and the correct hospital treatment remain key issues since these may influence mortality. The chances of the critically ill patients could be improved solely by a high-quality and careful critical care. It is prudent to meet the experiences of colleagues working hard with these patients in the already heavily infected countries. Orv Hetil. 2020; 161(17): 667­671.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #216081
    Database COVID19

    Kategorien

  7. Article: [Importance of imaging diagnostics in the care of COVID-19 infected patients]

    Lovas, Andras / Hankovszky, Peter / Korsos, Anita / Kupcsulik, Szilvia / Molnar, Tamas / Szabo, Zsolt / Babik, Barna

    Orv Hetil

    Abstract: The recent coronavirus epidemic poses a serious challenge to practicing intensive care physicians due to the high incidence of hypoxic respiratory failure Because pneumonia plays a prominent role in the critical pathomechanism of COVID-19, imaging ... ...

    Abstract The recent coronavirus epidemic poses a serious challenge to practicing intensive care physicians due to the high incidence of hypoxic respiratory failure Because pneumonia plays a prominent role in the critical pathomechanism of COVID-19, imaging studies are at the forefront of both the diagnosis and follow-up of the disease and the detection of potential complications Reviewing the literature data so far, we present the characteristic differences between chest CT, chest X-ray and chest wall ultrasound, and make recommendations for the use of different examination modalities The initial, atypical appearance of the viral infection is the CT-detected right lower lobe, peripheral, multifocal milk glass haze, which soon degenerates into a bilateral lesion affecting the middle and lower lung fields As the disease progresses, the proportion of consolidated areas increases, followed by a fibrotic pattern enhancement Due to special infection control rules for SARS-CoV-2 virus, bedside ultrasound plays an important role in keeping infected patients in contact with as few healthcare professionals as possible Orv Hetil 2020;161 (17): 672-677
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #120517
    Database COVID19

    Kategorien

  8. Article ; Online: A képalkotó diagnosztika jelentősége a COVID–19-fertőzött betegek ellátásában

    Lovas, András / Hankovszky, Péter / Korsós, Anita / Kupcsulik, Szilvia / Molnár, Tamás / Szabó, Zsolt / Babik, Barna

    2020  

    Keywords covid19
    Language Hungarian
    Publishing country hu
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Diagnosztikus lépések és a betegség prognózisának becslése COVID–19-fertőzött betegeken

    Korsós, Anita / Kupcsulik, Szilvia / Lovas, András / Hankovszky, Péter / Molnár, Tamás / Szabó, Zsolt / Babik, Barna

    2020  

    Keywords covid19
    Language Hungarian
    Publishing country hu
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

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