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Artikel ; Online: Investigation of the effects of Gamma Knife radiosurgery on optic pathways using diffusion tensor MRI within the first year after treatment.

Yazol, Merve / Ozer, Halil / Asfuroglu, Berrak Barutcu / Kurt, Gökhan / Emmez, Ömer Hakan / Öner, Ali Yusuf

2024 Band 66, Heft 4, Seite(n) 609–620

Abstract: Purpose: To investigate the radiation-induced effects of Gamma Knife radiosurgery (GKRS) for sellar-parasellar tumors on optic pathways using DTI parameters within the first year after treatment.: Methods: Twenty-five patients with sellar-parasellar ... ...

Abstract	Purpose: To investigate the radiation-induced effects of Gamma Knife radiosurgery (GKRS) for sellar-parasellar tumors on optic pathways using DTI parameters within the first year after treatment. Methods: Twenty-five patients with sellar-parasellar tumors underwent MRI before and 3 months after GKRS, including T1WI, DTI, T2WI. Moreover, 21 patients underwent follow-up DTI 6-8 months after radiosurgery. ROIs were set on optic nerves, optic radiations, and control localizations; DTI parameters for each were calculated. Pre- and post-radiosurgery differences in DTI values were statistically compared and assessed with respect to tumor size changes. Results: Following GKRS, DTI parameters, notably ADC, FA, and RD, showed statistically significant changes in optic nerves and anterior optic radiations. DTI changes were more significant in the group of cases with tumor shrinkage. In this group, DTI of the anterior optic radiations further deteriorated 3 months post-GKRS, whereas acute changes in DTI parameters of the optic nerves resolved within 6-8 months. DTI of central and posterior optic radiations did not differ significantly following radiosurgery; 6-8 months after radiosurgery, visual function was stable in 14 (56%) patients and improved in 11 (44%), showing no correlation with tumor size changes or DTI parameters. Conclusion: White Matter (WM) injury in the optic pathways can be induced by Gamma Knife radiosurgery targeted to sellar and parasellar tumors. Following GKRS, microstructural abnormalities occurred in the optic radiations as well as the optic nerves within the first post-treatment year. Our findings could support modifications to radiosurgical treatment strategies to minimize the risk of permanent WM injury.
Mesh-Begriff(e)	Humans ; Diffusion Tensor Imaging/methods ; Radiosurgery/methods ; Magnetic Resonance Imaging ; Meningeal Neoplasms/surgery ; Optic Nerve ; Treatment Outcome ; Follow-Up Studies ; Retrospective Studies
Sprache	Englisch
Erscheinungsdatum	2024-02-16
Erscheinungsland	Germany
Dokumenttyp	Journal Article
ZDB-ID	123305-1
ISSN	1432-1920 ; 0028-3940
ISSN (online)	1432-1920
ISSN	0028-3940
DOI	10.1007/s00234-024-03296-0
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Thioredoxin System and miR-21, miR-23a/b and let-7a as Potential Biomarkers for Brain Tumor Progression: Preliminary Case Data.

Kılıç, Nedret / Boyacıoğlu, Özge / Saltoğlu, Gamze Turna / Bulduk, Erkut Baha / Kurt, Gökhan / Korkusuz, Petek

World neurosurgery

2022 Band 167, Seite(n) e1299–e1309

Abstract: Background: The thioredoxin system and microRNAs (miRNAs) are potential targets for both cancer progression and treatment. However, the role of miRNAs and their relation with the expression profile of thioredoxin system in brain tumor progression ... ...

Abstract	Background: The thioredoxin system and microRNAs (miRNAs) are potential targets for both cancer progression and treatment. However, the role of miRNAs and their relation with the expression profile of thioredoxin system in brain tumor progression remains unclear. Methods: In this study, we aimed to determine the expression profiles of redox components Trx-1, TrxR-1 and PRDX-1, and oncogenic miR-21, miR-23a/b and let-7a and oncosuppressor miR-125 in different brain tumor tissues and their association with increasing tumor grade. We studied Trx-1, TrxR-1, and PRDX-1 messenger RNA expression levels by quantitative real-time polymerase chain reaction and protein levels by Western blot and miR-23a, miR-23b, miR-125a, miR-21, and let-7a miRNA expression levels by quantitative real-time polymerase chain reaction in 16 glioma, 15 meningioma, 5 metastatic, and 2 benign tumor samples. We also examined Trx-1, TrxR-1, and PRDX-1 protein levels in serum samples of 36 patients with brain tumor and 37 healthy volunteers by enzyme-linked immunosorbent assay. Results: We found that Trx-1, TrxR-1, and PRDX-1 presented high messenger RNA expression but low protein expression in low-grade brain tumor tissues, whereas they showed higher protein expression in sera of patients with low-grade brain tumors. miR-23b, miR-21, miR-23a, and let-7a were highly expressed in low-grade brain tumor tissues and positively correlated with the increase in thioredoxin system activity. Conclusions: Our findings showed that Trx-1, TrxR-1, miR-21, miR-23a/b, and let-7a might be used for brain tumor diagnosis in the clinic. Further prospective studies including molecular pathway analyses are required to validate the miRNA/Trx system regulatory axis in brain tumor progression.
Mesh-Begriff(e)	Humans ; Biomarkers ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Brain Neoplasms/diagnosis ; Brain Neoplasms/genetics ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Prospective Studies ; RNA, Messenger ; Thioredoxins/genetics
Chemische Substanzen	Biomarkers ; Biomarkers, Tumor ; MicroRNAs ; MIRN21 microRNA, human ; RNA, Messenger ; Thioredoxins (52500-60-4) ; MIRN23a microRNA, human ; MIRN23b microRNA, human ; mirnlet7 microRNA, human
Sprache	Englisch
Erscheinungsdatum	2022-09-09
Erscheinungsland	United States
Dokumenttyp	Journal Article
ZDB-ID	2534351-8
ISSN	1878-8769 ; 1878-8750
ISSN (online)	1878-8769
ISSN	1878-8750
DOI	10.1016/j.wneu.2022.09.024
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Dynamic contrast-enhanced magnetic resonance imaging for evaluating early response to radiosurgery in patients with vestibular schwannoma.

Özer, Halil / Yazol, Merve / Erdoğan, Nesrin / Emmez, Ömer Hakan / Kurt, Gökhan / Öner, Ali Yusuf

Japanese journal of radiology

2022 Band 40, Heft 7, Seite(n) 678–688

Abstract: Purpose: This study aimed to use dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) to evaluate early treatment response in vestibular schwannoma (VS) patients after radiosurgery.: Methods: Twenty-four VS patients who underwent gamma ... ...

Abstract	Purpose: This study aimed to use dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) to evaluate early treatment response in vestibular schwannoma (VS) patients after radiosurgery. Methods: Twenty-four VS patients who underwent gamma knife radiosurgery were prospectively followed up for at least four years. DCE-MRI sequences, in addition to standard MRI protocol, were obtained prior to radiosurgery, at 3 and 6 months. Conventionally, treatment responses based on tumor volume changes were classified as regression or stable (RS), transient tumor enlargement (TTE), and continuous tumor enlargement (CTE). DCE-MRI parameters, such as K Results: Changes in tumor volume were as follows at the last 48 months of follow-up: RS in 11 patients (45.8%), TTE in 10 patients (41.7%), and CTE in three patients (12.5%). The median time required to distinguish TTE from CTE using conventional MRI was 12 months (range 9-18). The K Conclusion: DCE-MRI may aid in the monitoring and early prediction of treatment response in patients with VS following radiosurgery.
Mesh-Begriff(e)	Contrast Media ; Humans ; Magnetic Resonance Imaging/methods ; Neuroma, Acoustic/diagnostic imaging ; Neuroma, Acoustic/radiotherapy ; Neuroma, Acoustic/surgery ; ROC Curve ; Radiosurgery/methods ; Tumor Burden
Chemische Substanzen	Contrast Media
Sprache	Englisch
Erscheinungsdatum	2022-01-17
Erscheinungsland	Japan
Dokumenttyp	Journal Article
ZDB-ID	2488907-6
ISSN	1867-108X ; 1867-1071
ISSN (online)	1867-108X
ISSN	1867-1071
DOI	10.1007/s11604-021-01245-y
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Stereotactic radiosurgery for tumors of the pineal region: A single-center experience.

Zeynal, Mete / Karaaslan, Burak / Dağli, Özlem / Börcek, Alp / Kurt, Gökhan / Kadioğlu, Hakan Hadi / Emmez, Ömer Hakan

Medicine

2023 Band 102, Heft 27, Seite(n) e34005

Abstract: Tumors of the pineal region (TPRs) are rare neoplasms that are surgically challenging to resect. Conventional treatment strategies are available, but gamma knife radiosurgery (GKRS) is an alternative approach. This study presents a single-center ... ...

Abstract	Tumors of the pineal region (TPRs) are rare neoplasms that are surgically challenging to resect. Conventional treatment strategies are available, but gamma knife radiosurgery (GKRS) is an alternative approach. This study presents a single-center experience with GKRS performed for TPR with and without histopathological diagnoses. The cases of 25 patients with TPRs treated with GKRS were retrospectively analyzed. Thirteen of these 25 patients had histopathological confirmation, and 13 had elevated serum alpha-fetoprotein and beta-human chorionic gonadotropin levels. The 25 patients had a mean follow-up duration of 61 months. The total response rate to GKRS was 60%, and a 53.8% decrease in the alpha-fetoprotein and beta human chorionic gonadotropin levels was observed. The findings of this study indicate that GKRS is a safe procedure for TPRs, even in the event of insufficient histopathological findings. This treatment approach provides increased Karnofsky performance scores and an extended life expectancy.
Mesh-Begriff(e)	Humans ; Follow-Up Studies ; Radiosurgery/methods ; alpha-Fetoproteins ; Pinealoma/radiotherapy ; Pinealoma/surgery ; Retrospective Studies ; Pineal Gland/surgery ; Pineal Gland/pathology ; Brain Neoplasms/radiotherapy ; Brain Neoplasms/surgery ; Brain Neoplasms/pathology ; Chorionic Gonadotropin ; Treatment Outcome
Chemische Substanzen	alpha-Fetoproteins ; Chorionic Gonadotropin
Sprache	Englisch
Erscheinungsdatum	2023-07-07
Erscheinungsland	United States
Dokumenttyp	Journal Article
ZDB-ID	80184-7
ISSN	1536-5964 ; 0025-7974
ISSN (online)	1536-5964
ISSN	0025-7974
DOI	10.1097/MD.0000000000034005
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel: Results of Chordoma Patients Treated by Different Approaches in a Single Institution.

Akmansu, Muge / Kurt, Gokhan / Demircan, Volkan / Senturk, Ertugrul

Turkish neurosurgery

2019 Band 30, Heft 3, Seite(n) 366–370

Abstract: Aim: To discuss the optimal and recent treatment options based on clinical review of 16 chordoma patients.: Material and methods: Data of the patients diagnosed and treated between 1999 and 2017 in Gazi University School of Medicine has been ... ...

Abstract	Aim: To discuss the optimal and recent treatment options based on clinical review of 16 chordoma patients. Material and methods: Data of the patients diagnosed and treated between 1999 and 2017 in Gazi University School of Medicine has been collected through patientsâ€™ files and the electronic database of hospital records. Statistical analysis was applied to evaluate the correlation between the progression free survival and treatment modalities. Results: Nine of the 16 patients were women (56.3%). Half of the patients had intracranially located tumors, whereas the other 50% of the sample had spinal (n=5) and sacral (n=3) chordomas. The median follow-up time was 51.7 months. Recurrence was observed in 50% of patients, while the median recurrence time equaled to 27.6 months. Multivariate analysis results showed that age, gender tumor size, intra or extracranial location of tumor, treatment modalities, subtotal or grosstotal resection of tumor, radiotherapy dose, and techniques were not associated with recurrence. On the other hand, 2 patients are still under chemoterapy (imatinib, bevacizumab) without evident of recurrent disease. Conclusion: Despite the fact that surgery remains to be the cornerstone of treatment, total resection is not reasonable for all patients with chordomas. For this reason, adjuvant treatment for ensuring local control is highly important. If the residual tumor is of a small volume, SBRT may provide more advantages. Targeted treatment or chemotheapeutic agents may also be benificial for maintanence therapy. As the clinical awareness about chordomas is based on our series, aggressive multi-modality treatment options should be applied in the adjuvant therapy.
Mesh-Begriff(e)	Adult ; Aged ; Aged, 80 and over ; Antineoplastic Combined Chemotherapy Protocols/administration & dosage ; Brain Neoplasms/diagnosis ; Brain Neoplasms/therapy ; Chordoma/diagnosis ; Chordoma/therapy ; Combined Modality Therapy/methods ; Female ; Humans ; Male ; Middle Aged ; Neoplasm, Residual/diagnosis ; Neoplasm, Residual/therapy ; Neurosurgical Procedures/methods ; Sacrum/pathology ; Sacrum/surgery ; Skull Base Neoplasms/diagnosis ; Skull Base Neoplasms/therapy ; Spinal Neoplasms/diagnosis ; Spinal Neoplasms/therapy ; Treatment Outcome
Sprache	Englisch
Erscheinungsdatum	2019-12-09
Erscheinungsland	Turkey
Dokumenttyp	Journal Article
ZDB-ID	1203779-5
ISSN	1019-5149
ISSN	1019-5149
DOI	10.5137/1019-5149.JTN.24406-19.4
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Aggravation of seizures and status epilepticus after vagal nerve stimulation therapy: the first pediatric case and review of the literature.

Arhan, Ebru / Serdaroğlu, Ayşe / Hirfanoğlu, Tuğba / Kurt, Gökhan

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

2018 Band 34, Heft 9, Seite(n) 1799–1801

Abstract: Background: We describe the first child with drug-resistant epilepsy in whom vagus nerve stimulation aggravated seizures and emerged status epilepticus after the increase in vagal nerve stimulation current output.: Objective: A 13-year-old girl ... ...

Abstract	Background: We describe the first child with drug-resistant epilepsy in whom vagus nerve stimulation aggravated seizures and emerged status epilepticus after the increase in vagal nerve stimulation current output. Objective: A 13-year-old girl presented with refractory secondary generalized focal epilepsy. Vagal nerve stimulator was implanted because of drug-resistant epilepsy. After the increase of vagal nerve stimulator current output to a relatively high level, the patient experienced seizure aggravation and status epilepticus. Conclusion: We conclude that vagus nerve stimulation may induce paradoxical seizures and may lead to status epilepticus, similarly to some antiepileptic drugs.
Mesh-Begriff(e)	Child ; Drug Resistant Epilepsy/diagnostic imaging ; Drug Resistant Epilepsy/therapy ; Humans ; Seizures/diagnostic imaging ; Seizures/etiology ; Status Epilepticus/diagnostic imaging ; Status Epilepticus/etiology ; Vagus Nerve Stimulation/adverse effects
Sprache	Englisch
Erscheinungsdatum	2018-04-22
Erscheinungsland	Germany
Dokumenttyp	Case Reports ; Journal Article ; Review
ZDB-ID	605988-0
ISSN	1433-0350 ; 0302-2803 ; 0256-7040
ISSN (online)	1433-0350
ISSN	0302-2803 ; 0256-7040
DOI	10.1007/s00381-018-3806-x
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Different Aspects on Clinical Presentation of Developmental Venous Anomalies: Are They as Benign as Known? A Single Center Experience.

Kurt, Gökhan / Aslan, Ayfer / Kara, Enes / Erol, Gökberk / Şahin, Merve Büke / Uçar, Murat

Clinical neurology and neurosurgery

2020 Band 201, Seite(n) 106443

Abstract: Background: Cerebral developmental venous anomalies (DVAs) are frequently diagnosed incidentally owing to the advances in neuroimaging. They are regarded as clinically insignificant due to their supposed quiescent existence which the authors aimed to ... ...

Abstract	Background: Cerebral developmental venous anomalies (DVAs) are frequently diagnosed incidentally owing to the advances in neuroimaging. They are regarded as clinically insignificant due to their supposed quiescent existence which the authors aimed to contradict in this paper. Aim: In the aim of constituting a better understanding of clinical presentation of DVAs and making an estimation regarding the probability of resulting in a hemorrhage, the authors presented their experiences with a case series of DVAs. Methods: A retrospective analysis was carried out among patients who underwent brain MRI in a radiology department of a university between January of 2019 and January of 2020. Results: A total of 101 patients with DVA were extracted. 38 patients had isolated DVAs, while 63 patients had various accompanying cerebral pathologies, mostly cavernomas (39 patients) and AVMs (11 patients). The main complaints leading investigation were headache, dizziness, ataxia, nausea\vomiting, seizures and focal neurological deficits. 41 patients were truly symptomatic with indicative findings of seizures, neurological deficits or intracranial hemorrhages, and 12 of them had solitary DVAs. 22 patients presented with hemorrhages, and of them, 10 had only DVA, while the rest had some associated lesions, most often cavernoma. Of 22 patients with hemorrhage, 5 were operated, 5 were applied radiosurgery; while the rest were followed without any intervention. Conclusion: Although the symptoms in patients with DVA are generally charged on other associated pathologies, the fact that isolated DVAs may occasionally be problematic in the range of minor symptoms and severe hemorrhage should not be underestimated.
Mesh-Begriff(e)	Adolescent ; Adult ; Aged ; Female ; Humans ; Intracranial Arteriovenous Malformations/complications ; Intracranial Arteriovenous Malformations/pathology ; Male ; Middle Aged ; Retrospective Studies ; Young Adult
Sprache	Englisch
Erscheinungsdatum	2020-12-18
Erscheinungsland	Netherlands
Dokumenttyp	Journal Article
ZDB-ID	193107-6
ISSN	1872-6968 ; 0303-8467
ISSN (online)	1872-6968
ISSN	0303-8467
DOI	10.1016/j.clineuro.2020.106443
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel: In Memorium: Professor Hizir Alp, 1933 - 2020.

Aykol, Sukru / Dogulu, Fikret / Kaymaz, Memduh / Kurt, Gokhan / Emmez, Hakan / Borcek, Alp Ozgun / Erdem, Munibe Busra

Turkish neurosurgery

2021 Band 31, Heft 2, Seite(n) 296–297

Sprache	Englisch
Erscheinungsdatum	2021-02-09
Erscheinungsland	Turkey
Dokumenttyp	Journal Article
ZDB-ID	1203779-5
ISSN	1019-5149
ISSN	1019-5149
DOI	10.5137/1019-5149.JTN.32961-20.0
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel: Stereotactic Radiosurgery after Subtotal Resection of Critically-Located Grade I Meningioma: A Single-Center Experience and Review of Literature.

Karaaslan, Burak / Celtikci, Emrah / Bulduk, Erkut Baha / Borcek, Alp Ozgun / Kurt, Gokhan / Kaymaz, Memduh / Aykol, Sukru / Emmez, Hakan

Turkish neurosurgery

2021 Band 31, Heft 4, Seite(n) 519–529

Abstract: Aim: To analyze the results of stereotactic radiosurgery in 295 patients with residual Grade I meningiomas located at parasellar region, petroclival region, cerebellopontine angle and parasagittal region.: Material and methods: A total of 295 ... ...

Abstract	Aim: To analyze the results of stereotactic radiosurgery in 295 patients with residual Grade I meningiomas located at parasellar region, petroclival region, cerebellopontine angle and parasagittal region. Material and methods: A total of 295 patients with Grade 1 residual Meningiomas (197 women, 98 men), who were treated by adjuvant radiosurgery in Gazi University Gamma Knife Center between 2004-2015 were analyzed. WHO Grade 2 and 3 meningiomas were not included in our study. Minimum radiological follow-up was 24 months. The median follow-up was 54 months. The tumor volume, location, treatment dose, morbidity, progression free survival and tumor control rate were analyzed. Results: The median tumor volume was 5.2 cm3 (0.04-39.7), median age was 50 (20-80), median dose was 14 Gy and tumor control rate was 94.5% (stationary in 85.0%, volume reduction in 9.5%). Increase in tumor volume was seen in 16 patients (5.5%) and re-operation was performed in 5 of them (1.6%). Stereotactic radiosurgery was performed again for 8 patients (2.7%).The location of the tumors was as follows: 39.3% parasellar region, 20% cerebellopontine angle, 13.6% petroclival and 27.1% was parasagittal, falcine or convexity. Major morbidities were detected in 6 (2%) patients. Minor morbidities were detected in 18 (6.1%) patients. Conclusion: Stereotactic radiosurgery is an effective and safe treatment modality for residual Grade I meningiomas.
Mesh-Begriff(e)	Adult ; Aged ; Aged, 80 and over ; Combined Modality Therapy ; Critical Illness/epidemiology ; Critical Illness/therapy ; Disease Progression ; Female ; Follow-Up Studies ; Humans ; Male ; Meningeal Neoplasms/epidemiology ; Meningeal Neoplasms/pathology ; Meningeal Neoplasms/radiotherapy ; Meningeal Neoplasms/surgery ; Meningioma/epidemiology ; Meningioma/pathology ; Meningioma/radiotherapy ; Meningioma/surgery ; Middle Aged ; Neurosurgical Procedures ; Radiosurgery/adverse effects ; Radiosurgery/methods ; Radiosurgery/statistics & numerical data ; Reoperation/statistics & numerical data ; Retrospective Studies ; Treatment Outcome ; Tumor Burden ; Young Adult
Sprache	Englisch
Erscheinungsdatum	2021-05-12
Erscheinungsland	Turkey
Dokumenttyp	Journal Article ; Review
ZDB-ID	1203779-5
ISSN	1019-5149
ISSN	1019-5149
DOI	10.5137/1019-5149.JTN.30181-20.2
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Stereotactic radiosurgery for cerebral cavernous malformation: comparison of hemorrhage rates before and after stereotactic radiosurgery.

Karaaslan, Burak / Gülsuna, Beste / Erol, Gökberk / Dağli, Özlem / Emmez, Hakan / Kurt, Gökhan / Çeltikçi, Emrah / Börcek, Alp Özgün

Journal of neurosurgery

2021 Band 136, Heft 3, Seite(n) 655–661

Abstract: Objective: Cerebral cavernous malformation (CM) is an angiographically occult vascular pathology. Although microsurgery is the gold standard treatment to control the symptoms of CM, resection carries high risk in some situations, especially eloquent ... ...

Abstract	Objective: Cerebral cavernous malformation (CM) is an angiographically occult vascular pathology. Although microsurgery is the gold standard treatment to control the symptoms of CM, resection carries high risk in some situations, especially eloquent areas. The objective was to evaluate annual hemorrhage rates (AHRs) before and after stereotactic radiosurgery (SRS) treatment of cerebral CM in different locations. Methods: A total of 195 patients (119 women and 76 men) with CM treated at the Gazi University Gamma Knife Center between April 2005 and June 2017 were analyzed. The mean ± SD follow-up period was 67.4 ± 31.1 months (range 12 days to 170 months). AHR before SRS, AHR after SRS, morbidity associated with radiation, seizure control rate after SRS, lesion volume, coexistence with developmental venous anomaly, and SRS treatment parameters were analyzed, with evaluation of radiological data and clinical charts performed retrospectively. The seizure control rate was assessed using the Engel outcome scale. Results: The AHR before SRS was 15.3%. Application of SRS to these patients significantly reduced the AHR rates to 2.6% during the first 2 years after treatment and to 1.4% thereafter. Favorable seizure control (Engel class I and II) after radiosurgery was achieved in 23 patients (88.5%) with epilepsy. Radiation-related temporary complications occurred in 15.4% of patients, and permanent morbidity occurred in 4.6%. Conclusions: SRS is a safe and effective treatment modality for reducing the hemorrhage risk of CM. The authors suggest that SRS should be considered for the treatment of patients with CM, high surgical risks, and hemorrhage history, instead of a using a wait-and-see policy.
Mesh-Begriff(e)	Female ; Follow-Up Studies ; Hemangioma, Cavernous, Central Nervous System/complications ; Hemangioma, Cavernous, Central Nervous System/radiotherapy ; Hemangioma, Cavernous, Central Nervous System/surgery ; Hemorrhage ; Humans ; Intracranial Arteriovenous Malformations/complications ; Intracranial Arteriovenous Malformations/diagnostic imaging ; Intracranial Arteriovenous Malformations/radiotherapy ; Male ; Radiation Injuries/etiology ; Radiosurgery/adverse effects ; Retrospective Studies ; Seizures/etiology ; Treatment Outcome
Sprache	Englisch
Erscheinungsdatum	2021-08-27
Erscheinungsland	United States
Dokumenttyp	Journal Article
ZDB-ID	3089-2
ISSN	1933-0693 ; 0022-3085
ISSN (online)	1933-0693
ISSN	0022-3085
DOI	10.3171/2021.2.JNS21138
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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