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  1. Article ; Online: Epidemiology and disease burden of patients requiring neurocritical care: a Brazilian multicentre cohort study.

    Réa-Neto, Álvaro / Bernardelli, Rafaella Stradiotto / de Oliveira, Mirella Cristine / David-João, Paula Geraldes / Kozesinski-Nakatani, Amanda Christina / Falcão, Antônio Luís Eiras / Kurtz, Pedro Martins Pereira / Teive, Hélio Afonso Ghizoni

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 18595

    Abstract: Acute neurological emergencies are highly prevalent in intensive care units (ICUs) and impose a substantial burden on patients. This study aims to describe the epidemiology of patients requiring neurocritical care in Brazil, and their differences based ... ...

    Abstract Acute neurological emergencies are highly prevalent in intensive care units (ICUs) and impose a substantial burden on patients. This study aims to describe the epidemiology of patients requiring neurocritical care in Brazil, and their differences based on primary acute neurological diagnoses and to identify predictors of mortality and unfavourable outcomes, along with the disease burden of each condition at intensive care unit admission. This prospective cohort study included patients requiring neurocritical care admitted to 36 ICUs in four Brazilian regions who were followed for 30 days or until ICU discharge (Aug-Sep in 2018, 1 month). Of 4245 patients admitted to the participating ICUs, 1194 (28.1%) were patients with acute neurological disorders requiring neurocritical care and were included. Patients requiring neurocritical care had a mean mortality rate 1.7 times higher than ICU patients not requiring neurocritical care (17.21% versus 10.1%, respectively). Older age, emergency admission, higher number of potential secondary injuries, and worse APACHE II, SAPS III, SOFA, and Glasgow coma scale scores on ICU admission are independent predictors of mortality and poor outcome among patients with acute neurological diagnoses. The estimated total DALYs were 4482.94 in the overall cohort, and the diagnosis with the highest DALYs was traumatic brain injury (1634.42). Clinical, epidemiological, treatment, and ICU outcome characteristics vary according to the primary neurologic diagnosis. Advanced age, a lower GCS score and a higher number of potential secondary injuries are independent predictors of mortality and unfavourable outcomes in patients requiring neurocritical care. The findings of this study are essential to guide education policies, prevention, and treatment of severe acute neurocritical diseases.
    MeSH term(s) Humans ; Brazil/epidemiology ; Prospective Studies ; Intensive Care Units ; Glasgow Coma Scale ; Cost of Illness ; Retrospective Studies
    Language English
    Publishing date 2023-10-30
    Publishing country England
    Document type Multicenter Study ; Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-44261-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Evaluation of the characteristics of infection prevention and control programs and infection control committees in Brazilian hospitals: A countrywide cross-sectional study.

    Arns, Beatriz / Agani, Crepin Aziz Jose Oluwafoumi / Sesin, Guilhermo Prates / Horvath, Jaqueline Driemeyer C / Fogazzi, Débora Vacaro / Romeiro Silva, Fernanda Kelly / Costa, Lauren Sezera / Pereira, Adriano Jose / Nassar Junior, Antônio Paulo / Cavalcanti, Bruno Tomazini / Dietrich, Camila / Veiga, Viviane Cordeiro / Catarino, Daniela G M / Cheno, Maysa Yukari / Biasi, Alexandre / Ferronatto, Bianca Ramos / Bassetti, Bil Randerson / Fernandes, Caio Cesar Ferreira / Deutschendorf, Caroline /
    Grion, Cintia Magalhães Carvalho / Vidal, Claudia Fernanda de Lacerda / de Oliveira, Cláudio Dornas / Caser, Eliana Bernadete / Boschi, Emerson / Silva, Everton Macêdo / Pizzol, Felipe Dal / Urbano, Hugo Correa de Andrade / Silva, Iany / Maia, Israel Silva / Rego, Leila Rezegue de Moraes / Oliveira, Luana Pontes / Tavares, Maria Brandão / Dracoulakis, Marianna Deway Andrade / Bainy, Marina Peres / Golin, Nicole Alberti / Tomba, Pablo Oscar / Kurtz, Pedro Martins Pereira / Foernges, Rafael Botelho / Prestes, Rejane Martins / de Melo, Rodrigo Morel Vieira / Da Silva, Rodrigo Reghini / Toledo, Tatiana Gozzi Pancev / Lima, Valéria Paes / Fernandes, Vanildes de Fátima / Lovato, Wilson José / Zavascki, Alexandre Prehn

    Antimicrobial stewardship & healthcare epidemiology : ASHE

    2023  Volume 3, Issue 1, Page(s) e79

    Abstract: Objective: Data are scarce regarding hospital infection control committees and compliance with infection prevention and control (IPC) recommendations in Brazil, a country of continental dimensions. We assessed the main characteristics of infection ... ...

    Abstract Objective: Data are scarce regarding hospital infection control committees and compliance with infection prevention and control (IPC) recommendations in Brazil, a country of continental dimensions. We assessed the main characteristics of infection control committees (ICCs) on healthcare-associated infections (HAIs) in Brazilian hospitals.
    Methods: This cross-sectional study was conducted in ICCs of public and private hospitals distributed across all Brazilian regions. Data were collected directly from the ICC staff by completing an online questionnaire and during on-site visits through face-to-face interviews.
    Results: In total, 53 Brazilian hospitals were evaluated from October 2019 to December 2020. All hospitals had implemented the IPC core components in their programs. All centers had protocols for the prevention and control of ventilator-associated pneumonia as well as bloodstream, surgical site, and catheter-associated urinary tract infections. Most hospitals (80%) had no budget specifically allocated to the IPC program; 34% of the laundry staff had received specific IPC training; and only 7.5% of hospitals reported occupational infections in healthcare workers.
    Conclusions: In this sample, most ICCs complied with the minimum requirements for IPC programs. The main limitation regarding ICCs was the lack of financial support. The findings of this survey support the development of strategic plans to improve IPCs in Brazilian hospitals.
    Language English
    Publishing date 2023-04-26
    Publishing country England
    Document type Journal Article
    ISSN 2732-494X
    ISSN (online) 2732-494X
    DOI 10.1017/ash.2023.136
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Erratum: Evaluation of the characteristics of infection prevention and control programs and infection control committees in Brazilian hospitals: A countrywide cross-sectional study - CORRIGENDUM.

    Arns, Beatriz / Agani, Crepin Aziz Jose Oluwafoumi / Sesin, Guilhermo Prates / Horvath, Jaqueline Driemeyer C / Fogazzi, Débora Vacaro / Romeiro Silva, Fernanda Kelly / Costa, Lauren Sezera / Pereira, Adriano Jose / Nassar Junior, Antônio Paulo / Cavalcanti, Bruno Tomazini / Dietrich, Camila / Veiga, Viviane Cordeiro / Catarino, Daniela G M / Cheno, Maysa Yukari / Biasi, Alexandre / Ferronatto, Bianca Ramos / Bassetti, Bil Randerson / Fernandes, Caio Cesar Ferreira / Deutschendorf, Caroline /
    Grion, Cintia Magalhães Carvalho / Vidal, Claudia Fernanda de Lacerda / de Oliveira, Cláudio Dornas / Caser, Eliana Bernadete / Boschi, Emerson / Silva, Everton Macêdo / Pizzol, Felipe Dal / Urbano, Hugo Correa de Andrade / Silva, Iany / Maia, Israel Silva / Rego, Leila Rezegue de Moraes / Oliveira, Luana Pontes / Tavares, Maria Brandão / Dracoulakis, Marianna Deway Andrade / Bainy, Marina Peres / Golin, Nicole Alberti / Tomba, Pablo Oscar / Kurtz, Pedro Martins Pereira / Foernges, Rafael Botelho / Prestes, Rejane Martins / de Melo, Rodrigo Morel Vieira / Da Silva, Rodrigo Reghini / Toledo, Tatiana Gozzi Pancev / Lima, Valéria Paes / Fernandes, Vanildes de Fátima / Lovato, Wilson José / Zavascki, Alexandre Prehn

    Antimicrobial stewardship & healthcare epidemiology : ASHE

    2023  Volume 3, Issue 1, Page(s) e102

    Abstract: This corrects the article DOI: 10.1017/ash.2023.136.]. ...

    Abstract [This corrects the article DOI: 10.1017/ash.2023.136.].
    Language English
    Publishing date 2023-06-19
    Publishing country England
    Document type Published Erratum
    ISSN 2732-494X
    ISSN (online) 2732-494X
    DOI 10.1017/ash.2023.189
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Comparison between respiratory pulse oximetry plethysmographic waveform amplitude and arterial pulse pressure variations among patients with and without norepinephrine use.

    Penna, Guilherme Loures de Araújo / Rosa, Paula Araujo / Kurtz, Pedro Martins Pereira / Braga, Fabricio / Almeida, Gustavo Ferreira / Freitas, Marcia / Drumond, Luis Eduardo / Souza, Ronaldo Vegni E / Cukier, Michel Schatkin / Salgado, André / Faria, Clóvis / Kezen, José / Japiassú, André Miguel / Kalichsztein, Marcelo / Nobre, Gustavo

    Revista Brasileira de terapia intensiva

    2009  Volume 21, Issue 4, Page(s) 349–352

    Abstract: Objectives: Arterial pulse pressure respiratory variation is a good predictor of fluid response in ventilated patients. Recently, it was shown that respiratory variation in arterial pulse pressure correlates with variation in pulse oximetry ... ...

    Title translation Comparação entre as variações respiratórias da amplitude de onda pletismográfica da oximetria de pulso e do pulso arterial em pacientes com e sem uso de norepinefrina.
    Abstract Objectives: Arterial pulse pressure respiratory variation is a good predictor of fluid response in ventilated patients. Recently, it was shown that respiratory variation in arterial pulse pressure correlates with variation in pulse oximetry plethysmographic waveform amplitude. We wanted to evaluate the correlation between respiratory variation in arterial pulse pressure and respiratory variation in pulse oximetry plethysmographic waveform amplitude, and to determine whether this correlation was influenced by norepinephrine administration.
    Methods: Prospective study of sixty patients with normal sinus rhythm on mechanical ventilation, profoundly sedated and with stable hemodynamics. Oxygenation index and invasive arterial pressure were monitored. Respiratory variation in arterial pulse pressure and respiratory variation in pulse oximetry plethysmographic waveform amplitude were recorded simultaneously in a beat-to-beat evaluation, and were compared using the Pearson coefficient of agreement and linear regression.
    Results: Thirty patients (50%) required norepinephrine. There was a significant correlation (K = 0.66; p < 0.001) between respiratory variation in arterial pulse pressure and respiratory variation in pulse oximetry plethysmographic waveform amplitude. Area under the ROC curve was 0.88 (range, 0.79 - 0.97), with a best cutoff value of 14% to predict a respiratory variation in arterial pulse pressure of 13. The use of norepinephrine did not influence the correlation (K = 0.63, p = 0.001, respectively).
    Conclusions: Respiratory variation in arterial pulse pressure above 13% can be accurately predicted by a respiratory variation in pulse oximetry plethysmographic waveform amplitude of 14%. The use of norepinephrine does not alter this relationship.
    Language Portuguese
    Publishing date 2009-12
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 2732162-9
    ISSN 1982-4335 ; 0103-507X
    ISSN (online) 1982-4335
    ISSN 0103-507X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Early predictive factors for intensive care unit readmission.

    Japiassú, André Miguel / Cukier, Michel Schatkin / Queiroz, Ana Gabriela Coelho de Magalhães / Gondim, Carlos Roberto Naegeli / Penna, Guilherme Loures de Araújo / Almeida, Gustavo Ferreira / Kurtz, Pedro Martins Pereira / Rodrigues, André Salgado / Freitas, Márcia Barbosa de / Souza, Ronaldo Vegni E / Rosa, Paula Araújo / Faria, Clovis Jean da Cruz / Drumond, Luis Eduardo Fonseca / Kalichsztein, Marcelo / Nobre, Gustavo Freitas

    Revista Brasileira de terapia intensiva

    2009  Volume 21, Issue 4, Page(s) 353–358

    Abstract: Objective: To predict readmission in intensive care unit analyzing the first 24 hours data after intensive care unit admission.: Methods: The first intensive care unit admission of patients was analyzed from January to May 2009 in a mixed unit. ... ...

    Title translation Fatores preditores precoces de reinternação em unidade de terapia intensiva.
    Abstract Objective: To predict readmission in intensive care unit analyzing the first 24 hours data after intensive care unit admission.
    Methods: The first intensive care unit admission of patients was analyzed from January to May 2009 in a mixed unit. Readmission to the unit was considered those during the same hospital stay or within 3 months after intensive care unit discharge. Deaths during the first admission were excluded. Demographic data, use of mechanical ventilation, and report of stay longer than 3 days were submitted to uni and multivariate analysis for readmission.
    Results: Five hundred seventy-seven patients were included (33 excluded deaths). The readmission group had 59 patients, while 518 patients were not readmitted. The lead time between the index admission and readmission was 9 (3-28) days (18 were readmitted in less than 3 days), and 10 died. Patients readmitted at least once to the intensive care unit had the differences below in comparison to the control group: older age: 75 (67-81) versus 67 (56-78) years, P<0.01; admission for respiratory insufficiency or sepsis: 33 versus 13%, P<0.01; medical admission: 49 versus 32%, P<0.05; higher SAPS II score: 27 (21-35) versus 23 (18-29) points, P<0.01; Charlson index: 2 (1-2) versus 1 (0-2) points, P<0.01; first ICU stay longer than 3 days: 35 versus 23%, P<0.01. After logistic regression, higher age, Charlson index and admission for respiratory and sepsis were independently associated to readmissions in intensive care unit.
    Conclusion: Age, comorbidities and respiratory- and/or sepsis-related admission are associated with increased readmission risk in the studied sample.
    Language Portuguese
    Publishing date 2009-12
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 2732162-9
    ISSN 1982-4335 ; 0103-507X
    ISSN (online) 1982-4335
    ISSN 0103-507X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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