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  1. Article ; Online: Metabolic Imbalances and Bone Remodeling Agents in Adolescent Idiopathic Scoliosis: A Study in Postmenarcheal Girls.

    Danielewicz, Anna / Wójciak, Magdalena / Sowa, Ireneusz / Kusz, Monika / Wessely-Szponder, Joanna / Dresler, Sławomir / Latalski, Michał

    International journal of molecular sciences

    2023  Volume 24, Issue 17

    Abstract: The causes and mechanisms underlying adolescent idiopathic scoliosis (AIS) remain unclear, and the available information regarding metabolic imbalances in AIS is still insufficient. This investigation aimed to evaluate the concentrations of specific bone ...

    Abstract The causes and mechanisms underlying adolescent idiopathic scoliosis (AIS) remain unclear, and the available information regarding metabolic imbalances in AIS is still insufficient. This investigation aimed to evaluate the concentrations of specific bone remodeling-related agents in postmenarcheal girls diagnosed with AIS. The study encompassed thirty-six scoliosis patients and eighteen age-matched healthy individuals assigned to the control group. The patients underwent clinical and radiological examinations to assess the degree of the spinal deformity, type of curvature, and skeletal maturity. Blood and urine samples were collected from all participants and serological markers were measured using an enzyme-linked immunosorbent assay. Our study results demonstrated that the balance of phosphate-calcium and parathormone levels seems normal in individuals with AIS. Furthermore, no statistically significant differences were observed in the content of Klotho protein, osteocalcin, osteoprotegerin, C-terminal telopeptide of type I collagen (CTX), sclerostin, and alkaline phosphatase. Nevertheless, the serum levels of vitamin D (25-OH-D) were lowered, while N-terminal propeptide of type I procollagen (PINP), and fibroblast growth factor-23 (FGF23) were increased in the AIS group, with
    MeSH term(s) Female ; Humans ; Adolescent ; Scoliosis ; Alkaline Phosphatase ; Bone Remodeling ; Collagen Type I
    Chemical Substances Procollagen Type I ; Alkaline Phosphatase (EC 3.1.3.1) ; Collagen Type I
    Language English
    Publishing date 2023-08-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms241713286
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Diagnostic conundrums of hypoganglionosis that may delay timely, optimal treatment.

    Alzubedi, Adam / Styliński, Roman / Polski, Paweł / Kusz, Monika / Matras, Przemysław / Rudzki, Sławomir

    Polish archives of internal medicine

    2020  Volume 130, Issue 11, Page(s) 992–994

    Language English
    Publishing date 2020-08-17
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 123500-x
    ISSN 1897-9483 ; 0032-3772
    ISSN (online) 1897-9483
    ISSN 0032-3772
    DOI 10.20452/pamw.15557
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 360: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  3. Article ; Online: Nephrocalcinosis in adolescent girl with medullary sponge kidney and mild hemihypertrophy: A case report.

    Kusz, Monika / Bieniaś, Beata / Wieczorkiewicz-Płaza, Anna / Brodzisz, Agnieszka / Wieczorek, Paweł / Sikora, Przemysław

    Medicine

    2019  Volume 98, Issue 7, Page(s) e14529

    Abstract: Rationale: Medullary sponge kidney (MSK) is a rare congenital abnormality characterized by cystic dilatation of the medullary collecting tubules. The disorder is likely to be complicated by nephrocalcinosis, urolithiasis, tubular dysfunctions, and ... ...

    Abstract Rationale: Medullary sponge kidney (MSK) is a rare congenital abnormality characterized by cystic dilatation of the medullary collecting tubules. The disorder is likely to be complicated by nephrocalcinosis, urolithiasis, tubular dysfunctions, and urinary tract infections. In addition, it may be rarely associated with extrarenal anomalies.
    Patient concern: We present a case of 17-year old girl who was referred for metabolic evaluation of bilateral nephrocalcinosis. Physical examination showed signs of mild, left-sided hemihypertrophy involving the lower limb, buttock, trunk, face, and tongue. The imaging studies of kidneys including intravenous urography and contrast computed tomography showed numerous medullary calcification and a typical picture of MSK-"paint brush"/"bouquet of flowers" appearance of the dilated tubules within the renal medulla. Laboratory evaluation revealed sterile pyuria, hypercalciuria, and hypocitraturia.
    Intervention: The patient was subsequently treated with potassium citrate, hydrochlorothiazide, low sodium and low oxalate diet accompanied by high fluid intake.
    Outcomes: After a 1-year therapy the normalization of calciuria and citraturia occurred and no progression of nephrocalcinosis was observed.
    Lessons: We conclude that MSK should always be considered as a cause of nephrocalcinosis. Since the final diagnosis requires specific imaging techniques, the concomitant extrarenal abnormalities such as hemihypertrophy may facilitate diagnostic decisions.
    MeSH term(s) Adolescent ; Diet Therapy ; Female ; Fluid Therapy ; Humans ; Hyperplasia/complications ; Kidney/diagnostic imaging ; Kidney/pathology ; Medullary Sponge Kidney/complications ; Nephrocalcinosis/complications ; Nephrocalcinosis/therapy
    Language English
    Publishing date 2019-02-11
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000014529
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.171: Show issues Location:
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  4. Article ; Online: A new way of presenting diagnostic imaging studies in surgical planning.

    Alzubedi, Adam / Kusz, Monika / Kuczyńska, Maryla / Białek, Wardemar / Bicki, Jacek / Rudzki, Sławomir

    Polski przeglad chirurgiczny

    2019  Volume 91, Issue 4, Page(s) 48–51

    Abstract: Technological advancement, availability and common use of diagnostic imaging slowly but consistently leads to a change in its nature from being additional studies to becoming the basis for diagnostic process and treatment planning especially in complex ... ...

    Abstract Technological advancement, availability and common use of diagnostic imaging slowly but consistently leads to a change in its nature from being additional studies to becoming the basis for diagnostic process and treatment planning especially in complex cases that require surgical treatment. CT angiography study presentation using the illusion called "Pepper's Ghost" in comparison to a three-dimensional printout and regular CT scan has been made to point out the relevance of research and implementation of new technologies in the diagnosis and surgical planning. Our image, despite being far from ideal and being just an illusion of a hologram, was more appealing and detailed to surgeons in comparison to a printed 3D model and standard CT angiography displayed with Osirix software. In order to change the existing methods of presenting imaging studies, it is advisable to use latest technologies, and among those currently available, ones based on virtual or mixed reality deserve special attention.
    MeSH term(s) Decision Making, Computer-Assisted ; Humans ; Image Processing, Computer-Assisted/methods ; Imaging, Three-Dimensional/methods ; Preoperative Care/methods ; Printing, Three-Dimensional/instrumentation ; Software
    Language English
    Publishing date 2019-09-03
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 128732-1
    ISSN 2299-2847 ; 0032-373X
    ISSN (online) 2299-2847
    ISSN 0032-373X
    DOI 10.5604/01.3001.0012.7271
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 375: Show issues Location:
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