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  1. Article ; Online: The impact of perioperative non-steroidal anti-inflammatory drugs use on pleurodesis following thoracic surgery.

    Kutywayo, Kudzayi / Habib, Akolade A / Caruana, Edward J

    Interdisciplinary cardiovascular and thoracic surgery

    2023  Volume 37, Issue 5

    Abstract: A best evidence topic in thoracic surgery was written according to a structured protocol. The question addressed was: in patients who have had {visceral and parietal pleural symphysis}, {do NSAIDs reduce} {the efficacy of pleurodesis}? Sixteen papers ... ...

    Abstract A best evidence topic in thoracic surgery was written according to a structured protocol. The question addressed was: in patients who have had {visceral and parietal pleural symphysis}, {do NSAIDs reduce} {the efficacy of pleurodesis}? Sixteen papers were discovered in the search. Of these, 3 human studies were included in the analysis. None showed a significantly higher rate of pleurodesis failure in patients given perioperative NSAIDs. The results from the largest study met criteria for noninferiority. Within the constraints of the study, the results suggest that systemic administration of nonsteroidal anti-inflammatory medication in the perioperative period does not necessarily attenuate effective pleurodesis. However, further study is needed as there is a clear paucity of human-based studies.
    Language English
    Publishing date 2023-09-04
    Publishing country England
    Document type Journal Article
    ISSN 2753-670X
    ISSN (online) 2753-670X
    DOI 10.1093/icvts/ivad107
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Outcome Reporting in Cardiac Surgery Systematic Reviews.

    Tyson, Nathan / Kutywayo, Kudzayi

    The Annals of thoracic surgery

    2021  Volume 114, Issue 1, Page(s) 353

    MeSH term(s) Cardiac Surgical Procedures ; Humans ; Research Design
    Language English
    Publishing date 2021-02-13
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 211007-6
    ISSN 1552-6259 ; 0003-4975
    ISSN (online) 1552-6259
    ISSN 0003-4975
    DOI 10.1016/j.athoracsur.2020.12.072
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: The chicken or the egg? A case of sympathetic staphylococcal empyema thoracis and splenic abscess.

    Kutywayo, Kudzayi H / Thekkudan, Joyce / Chowdhry, Mohammed Fiyaz

    Journal of surgical case reports

    2021  Volume 2021, Issue 11, Page(s) rjaa541

    Abstract: Multicavitary abscesses are uncommon in immunocompetent individuals. Splenic abscesses being relatively uncommon with an incidence of 0.1-0.7% in quoted series [ 1]. Commonly reported cases are secondary infective endocarditis. To have both a splenic ... ...

    Abstract Multicavitary abscesses are uncommon in immunocompetent individuals. Splenic abscesses being relatively uncommon with an incidence of 0.1-0.7% in quoted series [ 1]. Commonly reported cases are secondary infective endocarditis. To have both a splenic abscess and empyema concurrently is rare. We describe a case of a patient with a large left-sided empyema thoracis and concurrent splenic abscess.
    Language English
    Publishing date 2021-11-11
    Publishing country England
    Document type Case Reports
    ISSN 2042-8812
    ISSN 2042-8812
    DOI 10.1093/jscr/rjaa541
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Nonemphysematus Bullae Treatment Using Valves.

    Kutywayo, Kudzayi / Thekkudan, Joyce / Rathinam, Sridhar

    The Annals of thoracic surgery

    2021  Volume 113, Issue 2, Page(s) e157

    MeSH term(s) Humans ; Lung Diseases/complications ; Lung Diseases/diagnosis ; Lung Diseases/surgery ; Male ; Middle Aged ; Pulmonary Emphysema/diagnosis ; Pulmonary Emphysema/etiology ; Pulmonary Emphysema/surgery ; Thoracic Surgical Procedures/methods ; Tomography, X-Ray Computed
    Language English
    Publishing date 2021-02-23
    Publishing country Netherlands
    Document type Case Reports ; Journal Article
    ZDB-ID 211007-6
    ISSN 1552-6259 ; 0003-4975
    ISSN (online) 1552-6259
    ISSN 0003-4975
    DOI 10.1016/j.athoracsur.2020.11.092
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Uniportal VATS retrieval of an endobronchial coil migrated through pericardium.

    Kutywayo, Kudzayi / Acharya, Metesh N / Rathinam, Sridhar

    Journal of surgical case reports

    2020  Volume 2020, Issue 10, Page(s) rjaa108

    Abstract: Endobronchial insertion of nitinol coils is a minimally invasive treatment strategy for selected patients with advanced emphysema. Although coil migration into the pleural space has been described by ... ...

    Abstract Endobronchial insertion of nitinol coils is a minimally invasive treatment strategy for selected patients with advanced emphysema. Although coil migration into the pleural space has been described by Marchetti
    Language English
    Publishing date 2020-10-26
    Publishing country England
    Document type Case Reports
    ISSN 2042-8812
    ISSN 2042-8812
    DOI 10.1093/jscr/rjaa108
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Cytoreductive surgery with hyperthermic intrathoracic chemotherapy for malignant pleural mesothelioma: a systematic review.

    Dawson, Alan G / Kutywayo, Kudzayi / Mohammed, Seid B / Fennell, Dean A / Nakas, Apostolos

    Thorax

    2022  Volume 78, Issue 4, Page(s) 409–417

    Abstract: Introduction: Cytoreductive surgery has been used a part of multimodality treatment in patients with malignant pleural mesothelioma (MPM). The residual microscopic disease that remains will lead to disease progression in the majority of patients. ... ...

    Abstract Introduction: Cytoreductive surgery has been used a part of multimodality treatment in patients with malignant pleural mesothelioma (MPM). The residual microscopic disease that remains will lead to disease progression in the majority of patients. Delivery of hyperthermic intrathoracic chemotherapy at the time of surgery has been used to address this microscopic disease, however it's effect and place in the multimodality treatment sphere is unknown. The aim of this systematic review was to assess the effect of surgery and hyperthermic intrathoracic chemotherapy in patients with MPM on overall survival and disease-free interval.
    Methods: Ovid MEDLINE, Embase, Web of Science and the Cochrane Database of Systematic Reviews were searched from database inception through to June 2021. Studies reporting overall survival and/or disease-free interval in patients with MPM undergoing cytoreductive surgery with hyperthermic intrathoracic chemotherapy were considered. Study quality was assessed using the Newcastle-Ottawa Scale. A narrative review was performed.
    Results: Fifteen studies were eligible for inclusion comprising 598 patients. Surgery with hyperthermic intrathoracic chemotherapy was associated with a median overall survival and disease-free interval ranging from 11 to 75 months and 7.2 to 57 months, respectively. These appeared to be superior to patients not receiving hyperthermic intrathoracic chemotherapy (overall survival: 5-36 months and disease-free interval: 12.1-21 months). A higher dose of hyperthermic intrathoracic chemotherapy was associated with an improvement in overall survival compared with a lower dose: 18-31 months versus 6-18 months, respectively. The most common morbidity was atrial fibrillation followed by renal complications.
    Conclusion: Surgery with hyperthermic intrathoracic chemotherapy offers a safe and effective therapy with an improvement in disease-free interval and overall survival, particularly when hyperthermic intrathoracic chemotherapy is administered at a higher dose.
    Prospero registration number: CRD42019129002.
    MeSH term(s) Humans ; Mesothelioma, Malignant ; Mesothelioma/surgery ; Cisplatin/therapeutic use ; Cytoreduction Surgical Procedures ; Pleural Neoplasms/drug therapy ; Pleural Neoplasms/surgery ; Combined Modality Therapy
    Chemical Substances Cisplatin (Q20Q21Q62J)
    Language English
    Publishing date 2022-04-11
    Publishing country England
    Document type Review ; Journal Article ; Systematic Review
    ZDB-ID 204353-1
    ISSN 1468-3296 ; 0040-6376
    ISSN (online) 1468-3296
    ISSN 0040-6376
    DOI 10.1136/thoraxjnl-2021-218214
    Database MEDical Literature Analysis and Retrieval System OnLINE

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