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  1. Article ; Online: Editorial commentary: Functional mitral regurgitation - a moving target in patients with heart failure.

    Lipiecki, Janusz / Kuzemczak, Michał

    Trends in cardiovascular medicine

    2022  Volume 33, Issue 6, Page(s) 393–394

    MeSH term(s) Humans ; Mitral Valve Insufficiency ; Heart Failure/diagnosis ; Heart Failure/therapy ; Treatment Outcome ; Heart Valve Prosthesis Implantation
    Language English
    Publishing date 2022-03-24
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1097434-9
    ISSN 1873-2615 ; 1050-1738
    ISSN (online) 1873-2615
    ISSN 1050-1738
    DOI 10.1016/j.tcm.2022.03.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Letter by Alkhalil and Kuzemczak Regarding Article, "Comparative Efficacy and Safety of Oral P2Y12 Inhibitors in Acute Coronary Syndrome: Network Meta-Analysis of 52 816 Patients From 12 Randomized Trials".

    Alkhalil, Mohammad / Kuzemczak, Michał

    Circulation

    2021  Volume 143, Issue 6, Page(s) e234–e235

    MeSH term(s) Acute Coronary Syndrome/diagnosis ; Acute Coronary Syndrome/drug therapy ; Humans ; Network Meta-Analysis ; Purinergic P2Y Receptor Antagonists/adverse effects ; Randomized Controlled Trials as Topic ; Ticlopidine
    Chemical Substances Purinergic P2Y Receptor Antagonists ; Ticlopidine (OM90ZUW7M1)
    Language English
    Publishing date 2021-02-08
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80099-5
    ISSN 1524-4539 ; 0009-7322 ; 0069-4193 ; 0065-8499
    ISSN (online) 1524-4539
    ISSN 0009-7322 ; 0069-4193 ; 0065-8499
    DOI 10.1161/CIRCULATIONAHA.120.050967
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Shockwave intracoronary lithotripsy for the treatment of calcium-mediated undilatable in-stent restenosis.

    Kuzemczak, Michał / Pawłowski, Tomasz / Gil, Robert

    Cardiology journal

    2022  Volume 29, Issue 3, Page(s) 521–522

    MeSH term(s) Calcium ; Constriction, Pathologic ; Coronary Restenosis/diagnostic imaging ; Coronary Restenosis/etiology ; Humans ; Lithotripsy ; Stents
    Chemical Substances Calcium (SY7Q814VUP)
    Language English
    Publishing date 2022-06-01
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 2488680-4
    ISSN 1898-018X ; 1897-5593
    ISSN (online) 1898-018X
    ISSN 1897-5593
    DOI 10.5603/CJ.2022.0039
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Manual straightening of a brachial loop - a potential solution for challenging anatomies.

    Kuzemczak, Michał / Pawłowski, Tomasz / Gil, Robert

    Kardiologia polska

    2022  Volume 80, Issue 5, Page(s) 619–620

    Language English
    Publishing date 2022-03-25
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 411492-9
    ISSN 1897-4279 ; 0022-9032
    ISSN (online) 1897-4279
    ISSN 0022-9032
    DOI 10.33963/KP.a2022.0074
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Myocardial Replacement Therapy-the Quest for the Holy Grail Is Still in Progress.

    Kuzemczak, Michał / Siminiak, Tomasz

    The Annals of thoracic surgery

    2020  Volume 110, Issue 6, Page(s) 2104

    MeSH term(s) Bone Marrow Cells ; Cardiac Surgical Procedures ; Humans ; Myocardial Revascularization ; Myocardium ; Patients
    Language English
    Publishing date 2020-06-01
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 211007-6
    ISSN 1552-6259 ; 0003-4975
    ISSN (online) 1552-6259
    ISSN 0003-4975
    DOI 10.1016/j.athoracsur.2020.04.042
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Letter: Cardiac CT prior to percutaneous coronary sinus-based mitral annuloplasty with the Carillon device.

    Kuzemczak, Michał / Siminiak, Tomasz

    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology

    2020  Volume 16, Issue 10, Page(s) 862

    MeSH term(s) Computed Tomography Angiography ; Humans ; Mitral Valve/diagnostic imaging ; Mitral Valve/surgery ; Mitral Valve Annuloplasty/adverse effects ; Mitral Valve Insufficiency/diagnostic imaging ; Mitral Valve Insufficiency/surgery ; Percutaneous Coronary Intervention
    Language English
    Publishing date 2020-11-20
    Publishing country France
    Document type Journal Article ; Comment
    ZDB-ID 2457174-X
    ISSN 1969-6213 ; 1774-024X
    ISSN (online) 1969-6213
    ISSN 1774-024X
    DOI 10.4244/EIJ-D-20-00621L
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Colchicine for the prevention of ischemic stroke: An updated meta-analysis of randomized clinical trials.

    Al-Atta, Ayman / Kuzemczak, Michał / Alkhalil, Mohammad

    Brain circulation

    2021  Volume 7, Issue 3, Page(s) 187–193

    Abstract: Background: Inflammation is increasingly recognized as a target to reduce residual cardiovascular risk. Colchicine is an anti-inflammatory drug that was associated with improved cardiovascular outcomes. However, its effect on stroke reduction was not ... ...

    Abstract Background: Inflammation is increasingly recognized as a target to reduce residual cardiovascular risk. Colchicine is an anti-inflammatory drug that was associated with improved cardiovascular outcomes. However, its effect on stroke reduction was not consistent across studies. Therefore, the aim of this study-level meta-analysis was to evaluate the influence of colchicine on stroke in patients with coronary artery disease (CAD).
    Methods: Electronic databases were searched through October 2020, to identify randomized controlled trials using colchicine in patients with CAD. The incidence of clinical endpoints such as stroke, death, myocardial infarction (MI), study-defined major adverse cardiovascular events (MACE), and atrial fibrillation (AF) was compared between colchicine and placebo groups.
    Results: A total number of 11,594 (5,806 in the colchicine arm) patients from 4 eligible studies were included in the final analysis. Stroke incidence was lower in the colchicine arm compared to placebo (rate ratio [RR] 0.48 [95% confidence interval [CI], 0.29-0.78],
    Conclusions: This meta-analysis confirms a significant influence of colchicine on stroke in CAD patients. Despite its neutral effect on AF occurrence, other mechanisms related to plaque stabilization are plausible. The concept seems to be supported by contemporaneous MI reduction and posits that anti-inflammatory properties of colchicine may translate into a reduction of stroke risk.
    Language English
    Publishing date 2021-08-27
    Publishing country India
    Document type Journal Article
    ZDB-ID 2950273-1
    ISSN 2455-4626 ; 2394-8108
    ISSN (online) 2455-4626
    ISSN 2394-8108
    DOI 10.4103/bc.bc_24_21
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: ACE inhibitor-related angioedema in a COVID-19 patient-a plausible contribution of the viral infection?

    Kuzemczak, Michał / Kavvouras, Charalampos / Alkhalil, Mohammad / Osten, Mark

    European journal of clinical pharmacology

    2021  Volume 77, Issue 6, Page(s) 933–934

    MeSH term(s) Angioedema/chemically induced ; Angioedema/physiopathology ; Angioedema/therapy ; Angioedema/virology ; Angiotensin-Converting Enzyme Inhibitors/administration & dosage ; Angiotensin-Converting Enzyme Inhibitors/adverse effects ; COVID-19/complications ; COVID-19/diagnosis ; COVID-19/physiopathology ; COVID-19 Nucleic Acid Testing ; Cardiovascular Agents/administration & dosage ; Coronary Angiography/methods ; Drug Substitution/methods ; Humans ; Male ; Middle Aged ; Myocardial Infarction/complications ; Myocardial Infarction/diagnosis ; Myocardial Infarction/drug therapy ; Myocardial Infarction/physiopathology ; Patient Care Management ; Platelet Aggregation Inhibitors/administration & dosage ; Ramipril/administration & dosage ; Ramipril/adverse effects ; SARS-CoV-2 ; Treatment Outcome
    Chemical Substances Angiotensin-Converting Enzyme Inhibitors ; Cardiovascular Agents ; Platelet Aggregation Inhibitors ; Ramipril (L35JN3I7SJ)
    Language English
    Publishing date 2021-01-03
    Publishing country Germany
    Document type Case Reports ; Letter
    ZDB-ID 121960-1
    ISSN 1432-1041 ; 0031-6970
    ISSN (online) 1432-1041
    ISSN 0031-6970
    DOI 10.1007/s00228-020-03082-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Colchicine in Patients with Coronary Artery Disease with or Without Diabetes Mellitus: A Meta-analysis of Randomized Clinical Trials.

    Kuzemczak, Michał / Ibrahem, Abdalazeem / Alkhalil, Mohammad

    Clinical drug investigation

    2021  Volume 41, Issue 8, Page(s) 667–674

    Abstract: Background and objectives: Whether the anti-inflammatory drug colchicine has a differential treatment effect according to diabetes mellitus status in patients with coronary artery disease has never been studied. Therefore, the aim of the present meta- ... ...

    Abstract Background and objectives: Whether the anti-inflammatory drug colchicine has a differential treatment effect according to diabetes mellitus status in patients with coronary artery disease has never been studied. Therefore, the aim of the present meta-analysis was to evaluate whether the use of colchicine in patients with coronary artery disease with diabetes was associated with a higher magnitude of benefits compared to patients with coronary artery disease without diabetes.
    Methods: Electronic databases were searched through June 2020 to identify randomized clinical trials using colchicine in patients with coronary artery disease. Studies using blood biomarkers, such as troponin or high-sensitive C-reactive protein, as well as angiographic endpoints were excluded. The primary endpoint was major cardiovascular events as defined by the included studies.
    Results: In total, 11,594 patients from four randomized trials were included of whom 2278 (19.6%) had diabetes and 5540 (47.8%) presented with acute coronary syndrome. Colchicine was associated with almost twice the absolute risk reduction in patients with diabetes {absolute risk difference (ARD) - 3.94 [95% confidence interval (CI) - 1.28 to - 6.6], p = 0.004} compared with those without diabetes [ARD - 2.32 (95% CI - 1.32 to - 3.31), p < 0.001]. The magnitude of ARD between colchicine and placebo was significantly larger in patients with diabetes compared with patients without diabetes [ARD 1.62 (95% CI 1.43-1.81), p < 0.001]. When the analysis was restricted to patients presenting with acute coronary syndrome, the differential treatment effect of colchicine was more pronounced in patients with diabetes [ARD - 0.05 (95% CI - 0.08 to - 0.01), p = 0.02] compared with those without diabetes [ARD - 0.01 (95% CI - 0.02 to 0), p = 0.11].
    Conclusions: This meta-analysis underscores the heightened inflammatory risk associated with diabetes and highlights the need to target inflammatory pathways in these individuals irrespective of glucose-lowering drugs.
    MeSH term(s) Anti-Inflammatory Agents ; Colchicine/therapeutic use ; Coronary Artery Disease/drug therapy ; Diabetes Mellitus/drug therapy ; Diabetes Mellitus/epidemiology ; Humans ; Randomized Controlled Trials as Topic
    Chemical Substances Anti-Inflammatory Agents ; Colchicine (SML2Y3J35T)
    Language English
    Publishing date 2021-06-26
    Publishing country New Zealand
    Document type Journal Article ; Meta-Analysis
    ZDB-ID 1220136-4
    ISSN 1179-1918 ; 0114-2402 ; 1173-2563
    ISSN (online) 1179-1918
    ISSN 0114-2402 ; 1173-2563
    DOI 10.1007/s40261-021-01056-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Transcatheter Mitral Valve Repair: When Is the Last Moment Before Crossing the Styx River?

    Kuzemczak, Michał / Lipiecki, Janusz / Siminiak, Tomasz

    Journal of the American College of Cardiology

    2021  Volume 77, Issue 23, Page(s) 2982

    MeSH term(s) Humans ; Intracellular Signaling Peptides and Proteins ; Mitral Valve/diagnostic imaging ; Mitral Valve/surgery ; Mitral Valve Annuloplasty ; Mitral Valve Insufficiency/surgery ; Rivers
    Chemical Substances Intracellular Signaling Peptides and Proteins ; STYX protein, human
    Language English
    Publishing date 2021-06-09
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2021.03.336
    Database MEDical Literature Analysis and Retrieval System OnLINE

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