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  1. Article: Immediate placement of extra-short implants in refined scapula tip microvascular free flaps: In house virtual planning and surgical technique - Proof of concept.

    Jelovac, Drago / Micic, Milutin / Hajdarevic, Sanela / Kuzmanovic, Cedomir / Cukic, Branislav / Stefanovic, Branislav / Zelic, Ksenija / Bonfante, E A / Ewers, Rolf / Petrovic, Milan

    Heliyon

    2023  Volume 9, Issue 7, Page(s) e18021

    Abstract: Scapula tip flaps have been introduced in the literature as an ideal surgical treatment option for large defects in the horizontal plane of the maxilla. This article aims to present a unique step by step protocol for a near total maxillectomy with a ... ...

    Abstract Scapula tip flaps have been introduced in the literature as an ideal surgical treatment option for large defects in the horizontal plane of the maxilla. This article aims to present a unique step by step protocol for a near total maxillectomy with a pterygoid bone resection and consecutive microvascular reconstruction with a harvested scapula tip flap. The protocol includes immediate placement of extra-short implants in donor bone with the aid of Virtual Surgical Planning (VSP), and an in-house 3D printing of medical 3D models and surgical guides. So far, there has been no presented surgical technique combining immediate implant placement in the scapula region with simultaneous microvascular repair. This technique allows: tumour resection; flap harvesting; extra-short implant placements and reconstruction to be performed in one simultaneous procedure. The technique is presented with illustrations, VSP (presented on videos), radiographs, and surgical findings. We discovered that this refinement of the scapula tip surgery has enabled reconstructive procedures to be performed at the same time as implant placements, providing expedited functional and aesthetic outcomes in selected cases. Moreover, modification of the surgical technique could enhance the competence of the oropharyngeal edge. In conclusion, this new surgical protocol utilizing VSP, 3D models and simultaneous extra-short implant placement provides indispensable advantages for such a complicated surgical procedures, while significantly shortening the duration of surgery.
    Language English
    Publishing date 2023-07-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e18021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Medication-Related Osteonecrosis of the Jaws: Two Center Retrospective Cohort Studies.

    Petrovic, Milan / Jelovac, Drago B / Antic, Svetlana / Antunovic, Marija / Lukic, Nikola / Sabani, Melvil / Mudrak, Joerg / Jezdic, Zoran / Pucar, Ana / Stefanovic, Aleksandar / Kuzmanovic, Cedomir / Nikolic, Danilo / Konstantinovic, Vitomir

    BioMed research international

    2019  Volume 2019, Page(s) 8345309

    Abstract: This retrospective cohort study aims to describe characteristics of patients with MRONJ, to identify factors associated with MRONJ development, and to examine variables associated with favourable outcome. Totally 32 patients were followed and observed: ... ...

    Abstract This retrospective cohort study aims to describe characteristics of patients with MRONJ, to identify factors associated with MRONJ development, and to examine variables associated with favourable outcome. Totally 32 patients were followed and observed: 21 females and 11 males, in the age range 35-84 in the period from 2009 to 2018. Clinical, radiological examination (Orthopantomograph and CBCT) and biopsy were performed in order to achieve diagnosis. Demographic and clinical variables were taken into consideration: sex, age, primary disease, medication type, mode of delivery, anatomic location, drug treatment duration, timing of tooth extraction, chemotherapy, presence of bone metastasis, aetiology of MRONJ, disease stage, and treatment modality. MRONJ developed under osteoporosis and malignant disease in 11 and 21 patients, respectively. MRONJ development was triggered by tooth extraction or trauma in 30 out of 32 cases, whereas the two patients developed MRONJ spontaneously. Stages I, II, and III were confirmed in 5 (16%), 18 (58%), and 9 (28%) patients, respectively. Mandible was affected in 23 (72%) patients. MRONJ was treated in our department by conservative and surgical modality. In this study we found that 65% of all patients were classified in the cured/improvement group and 35% in the stable/progression group. The female gender, osteoporosis as primary disease, oral regime intake, shorter period on BPs, earlier stage of disease, and specific anatomic localisation (frontal and premolar maxilla) were factors associated with better response to therapy and favourable clinical outcome. Comprehensive treatment protocol and further randomized studies are necessary for further improvements.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Bisphosphonate-Associated Osteonecrosis of the Jaw/etiology ; Bisphosphonate-Associated Osteonecrosis of the Jaw/physiopathology ; Bone Density Conservation Agents/adverse effects ; Bone Neoplasms/physiopathology ; Diphosphonates/adverse effects ; Female ; Humans ; Male ; Middle Aged ; Osteoporosis/physiopathology ; Radiography, Panoramic/adverse effects ; Retrospective Studies ; Risk Factors ; Tooth Extraction/adverse effects
    Chemical Substances Bone Density Conservation Agents ; Diphosphonates
    Language English
    Publishing date 2019-03-18
    Publishing country United States
    Document type Journal Article ; Multicenter Study
    ZDB-ID 2698540-8
    ISSN 2314-6141 ; 2314-6133
    ISSN (online) 2314-6141
    ISSN 2314-6133
    DOI 10.1155/2019/8345309
    Database MEDical Literature Analysis and Retrieval System OnLINE

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