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  1. Article ; Online: Evaluation of Construction Cost, Time, and Sustainable Attributes of Drywalls Supported by Resilient Channels

    Kyung Ho Kim / Jin Yong Jeon

    Sustainability, Vol 12, Iss 8102, p

    2020  Volume 8102

    Abstract: In this study, a gypsum board wall was developed using resilient channels to improve sound insulation performance, constructability, and economic efficiency; the effect of the application of the developed wall on skyscrapers and long-term housing, one of ...

    Abstract In this study, a gypsum board wall was developed using resilient channels to improve sound insulation performance, constructability, and economic efficiency; the effect of the application of the developed wall on skyscrapers and long-term housing, one of the main forms of modern buildings, was also comprehensively evaluated. Resilient channels were inserted and fixed to ensure the constructability was suitable for high-rise buildings. In addition, the sound insulation performance, durability of the wall, CO 2 emissions, and life-cycle cost (LCC), which are key elements for economic efficiency, constructability, and sustainability, were analyzed. The developed lightweight gypsum board drywall with resilient channels was compared with a concrete wall as well as a double stud gypsum board wall, which has been most widely used among existing drywalls. The sound insulation performance and durability were evaluated in a laboratory, and the other items were evaluated after constructing the walls in a hotel building with an area of 2956 m 2 . The evaluation results show that the developed wall exhibited a 3 dB higher sound insulation performance than the concrete wall, even though it was thinner by 50 mm, and the wall secured the grade of “severe duty” (SD) based on the BS 5234-2 standard in durability evaluation, indicating that it can sufficiently replace concrete walls. Moreover, when the developed wall was installed in an actual building and compared with a concrete wall, a 14.7% reduction in construction cost, 59% reduction in CO 2 emissions, and 30.4% reduction in the LCC of the drywall, considering even the remodeling and dismantling stages of the building, were observed. Therefore, it was proven that the newly developed resilient channel drywall with improved constructability has significant value in terms of sound insulation performance, economic efficiency, safety, and eco-friendliness.
    Keywords sound insulation ; gypsum board ; life-cycle cost ; carbon dioxide ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Subject code 690
    Language English
    Publishing date 2020-10-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Improved Symptoms of Peripheral Facial Nerve Palsy in ChAdOx1 nCoV-19 Vaccine Recipients Following Complex Korean Medicine Treatment

    Woo Seok Jang / Jung Eun Jang / Chan Yung Jung / Kyung Ho Kim

    Journal of Acupuncture Research, Vol 39, Iss 2, Pp 139-

    2022  Volume 144

    Abstract: Peripheral facial nerve palsy is a neurological condition/disease characterized by unilateral paralysis of the facial muscles. We report the effects of complex Korean medicine treatment in 2 patients diagnosed with Bell’s palsy who developed symptoms 3–4 ...

    Abstract Peripheral facial nerve palsy is a neurological condition/disease characterized by unilateral paralysis of the facial muscles. We report the effects of complex Korean medicine treatment in 2 patients diagnosed with Bell’s palsy who developed symptoms 3–4 days following vaccination with ChAdOx1 nCoV-19 and who received oral steroids and antiviral medications. Complex Korean medicine treatments including acupuncture, electroacupuncture, bee venom acupuncture, cupping therapy, herbal medicine, and physical therapy were performed. Symptom improvement was evaluated daily using the Numerical Rating Scale, House-Brackmann Grade, and Yanagihara’s Score. Patient 1 was hospitalized for 22 days and Patient 2 visited the outpatient clinic 20 times. In both cases, postauricular pain caused by Bell’s palsy disappeared, and symptoms of facial paralysis improved following completion of treatment. These findings could suggest that combined Korean medicine treatment may improve symptoms of peripheral facial nerve palsy.
    Keywords bell palsy ; coronavirus ; cranial nerve diseases ; facial paralysis ; korean traditional medicine ; vaccines ; Miscellaneous systems and treatments ; RZ409.7-999 ; Therapeutics. Pharmacology ; RM1-950
    Language English
    Publishing date 2022-05-01T00:00:00Z
    Publisher E-Tree Publishing
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Capacitive coupling of coherent quantum phase slip qubits to a resonator

    Teresa Hönigl-Decrinis / Ilya Antonov / Rais Shaikhaidarov / Kyung Ho Kim / Vladimir N Antonov / Oleg V Astafiev

    New Journal of Physics, Vol 25, Iss 11, p

    2023  Volume 113020

    Abstract: We demonstrate capacitive coupling of coherent quantum phase slip (CQPS) flux qubits to a resonator patterned on a highly disordered TiN film. We are able to detect and characterise CQPS flux qubits with linewidths down to $\Delta\omega = 12\pm1\,\text{ ... ...

    Abstract We demonstrate capacitive coupling of coherent quantum phase slip (CQPS) flux qubits to a resonator patterned on a highly disordered TiN film. We are able to detect and characterise CQPS flux qubits with linewidths down to $\Delta\omega = 12\pm1\,\text{MHz}$ on several resonator modes, and show that, unlike inductive coupling, here the coupling strength does not depend on the qubit’s energy. Since the qubit is galvanically decoupled from the resonator, our approach provides flexibility in material, design and fabrication choices for CQPS-based devices. Our results are two-fold: we report CQPS in TiN and demonstrate, to our knowledge for the first time, capacitive coupling of a CQPS flux qubit.
    Keywords quantum phase slip ; cavity electrodynamics ; disordered superconductor ; superconducting qubits ; Science ; Q ; Physics ; QC1-999
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher IOP Publishing
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Data on molecular characterisation and expression analysis of the interferon-related developmental regulator 2 (IFRD2) gene from red sea bream, Pagrus major

    Kyung Ho Kim / Andre Kim / Chan-Il Park

    Data in Brief, Vol 25, Iss , Pp - (2019)

    2019  

    Abstract: The interferon-related developmental regulator 1 (IFRD1) protein is expected to play a role in the regulation of inflammatory responses in adult mice, since it is known to repress transcription of NF-κB in myoblasts that regenerate skeletal muscle after ... ...

    Abstract The interferon-related developmental regulator 1 (IFRD1) protein is expected to play a role in the regulation of inflammatory responses in adult mice, since it is known to repress transcription of NF-κB in myoblasts that regenerate skeletal muscle after traumatic injury Micheli et al., 2011. The IFRD2 gene is expressed in many tissues including skeletal muscle, kidney, heart, brain, lung, placenta and liver in adult humans and is highly expressed in adult human skeletal muscle and heart. In mice, interferon-related developmental regulator 2 (IFRD2) may be associated with early haematopoiesis after gastrulation and in the hepatic primordium Buanne et al., 1998. In this study, we analysed the molecular characteristics of the IFRD2 gene identified from Pagrus major (PmIFRD2) and performed multiple alignments and phylogenetic analyses of the protein sequence. In addition, we examined the expression pattern of IFRD2 in healthy red sea bream tissues and the temporal expression pattern after challenging with various pathogens [Edwardsiella piscicida (E. piscicida), Streptococcus iniae (S. iniae) and red sea bream iridovirus (RSIV)]. This study characterises the non-specific immune response of the red sea bream after viral and microbial infections. Keywords: Interferon-related developmental regulator 2 (IFRD2), Red sea bream, Edwardsiella piscicida, Streptococcus iniae, Red sea bream iridovirus (RSIV)
    Keywords Computer applications to medicine. Medical informatics ; R858-859.7 ; Science (General) ; Q1-390
    Subject code 572
    Language English
    Publishing date 2019-08-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Data on molecular characterization and expression of the C-reactive protein (CRP) gene from rock bream, Oplegnathus fasciatus

    Kyung Ho Kim / Do-Hyung Kim / Chan-Il Park

    Data in Brief, Vol 26, Iss , Pp - (2019)

    2019  

    Abstract: C-reactive protein (CRP) is a member of the pentraxin family and is an acute-phase response to plasma protein; its level in blood increases rapidly in response to trauma, inflammation, and infection. In the present study, we analysed the molecular ... ...

    Abstract C-reactive protein (CRP) is a member of the pentraxin family and is an acute-phase response to plasma protein; its level in blood increases rapidly in response to trauma, inflammation, and infection. In the present study, we analysed the molecular characteristics of the Oplegnathus fasciatus CRP (RbCRP) gene sequence using multiple alignments and phylogenetic analyses of the deduced amino acids. In addition, we also examined RbCRP gene expression in rock bream infected with the pathogens Edwardsiella piscicida (E. piscicida), Streptococcus iniae (S. iniae) or red sea bream iridovirus (RSIV) and in healthy rock bream individuals. In healthy individuals, RbCRP was ubiquitously expressed in all 14 tested tissues, mainly in the trunk kidney and head kidney. Expression of RbCRP was notably upregulated in the spleen and whole kidney after RSIV infection. This study can provide basic data on the innate immune system of the rock bream to viral and microbial infections. Keywords: C-reactive protein (CRP), Rock bream, Edwardsiella piscicida, Streptococcus iniae, Red sea bream iridovirus (RSIV)
    Keywords Computer applications to medicine. Medical informatics ; R858-859.7 ; Science (General) ; Q1-390
    Subject code 570
    Language English
    Publishing date 2019-10-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Impact of Red Sea Bream Iridovirus Infection on Rock Bream ( Oplegnathus fasciatus ) and Other Fish Species

    Kyung-Ho Kim / Gyoungsik Kang / Won-Sik Woo / Min-Young Sohn / Ha-Jeong Son / Mun-Gyeong Kwon / Jae-Ok Kim / Chan-Il Park

    Animals, Vol 13, Iss 1210, p

    A Study of Horizontal Transmission

    2023  Volume 1210

    Abstract: Red sea bream iridovirus (RSIV) causes significant economic losses in aquaculture. Here, we analyzed the pathogenicity, viral shedding, and transmission dynamics of RSIV in rock bream ( Oplegnathus fasciatus ) by employing immersion infection and ... ...

    Abstract Red sea bream iridovirus (RSIV) causes significant economic losses in aquaculture. Here, we analyzed the pathogenicity, viral shedding, and transmission dynamics of RSIV in rock bream ( Oplegnathus fasciatus ) by employing immersion infection and cohabitation challenge models. Rock bream challenged by immersion exposure exhibited 100% mortality within 35 days post RSIV exposure, indicating that the viral shedding in seawater peaked after mortality. At 25 °C, a positive correlation between the viral loads within infected rock bream and virus shedding into the seawater was observed. Specific RSIV lesions were observed in the spleen and kidney of the infected rock bream, and the viral load in the spleen had the highest correlation with the histopathological grade. A cohabitation challenge mimicking the natural transmission conditions was performed to assess the virus transmission and determine the pathogenicity and viral load. The RSIV-infected rock breams (donors) were cohabited with uninfected rock bream, red sea bream ( Pagrus major ), and flathead grey mullet ( Mugil cephalus ) (recipients) at both 25 °C and 15 °C. In the cohabitation challenge group maintained at 15 °C, no mortality was observed across all experimental groups. However, RSIV was detected in both seawater and the recipient fish. Our results provide preliminary data for further epidemiological analyses and aid in the development of preventive measures and management of RSIVD in aquaculture.
    Keywords Megalocytivirus ; histopathological ; viral shedding ; viral kinetics ; cohabitation challenge ; Veterinary medicine ; SF600-1100 ; Zoology ; QL1-991
    Subject code 333
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Exploring the Efficacy and Safety of Levamisole Hydrochloride against Microcotyle sebastis in Korean Rockfish ( Sebastes schlegelii )

    Won-Sik Woo / Gyoungsik Kang / Kyung-Ho Kim / Ha-Jeong Son / Min-Young Sohn / Ji-Hoon Lee / Jung-Soo Seo / Mun-Gyeong Kwon / Chan-Il Park

    Animals, Vol 13, Iss 1791, p

    An In Vitro and In Vivo Approach

    2023  Volume 1791

    Abstract: Parasitic infections pose significant challenges in aquaculture, and the increasing resistance to conventional anthelmintics necessitates the exploration of alternative treatments. Levamisole hydrochloride (HCl) has demonstrated efficacy against ... ...

    Abstract Parasitic infections pose significant challenges in aquaculture, and the increasing resistance to conventional anthelmintics necessitates the exploration of alternative treatments. Levamisole hydrochloride (HCl) has demonstrated efficacy against monogenean infections in various fish species; however, research focused on Microcotyle sebastis infections in Korean rockfish ( Sebastes schlegelii ) remains limited. Therefore, this study aimed to evaluate the efficacy of levamisole HCl against M. sebastis infections in Korean rockfish with the goal of optimizing anthelmintic usage in aquaculture. In this study, we first assessed the susceptibility of M. sebastis to levamisole HCl in vitro. Subsequently, in vivo evaluations were conducted to assess the drug’s efficacy, safety, and to identify optimal administration methods. In vitro experiments revealed concentration-dependent sensitivity of M. sebastis to levamisole HCl, with a minimum effective concentration (MEC) of 100 mg/L. In vivo experiments employed oral administration, intraperitoneal injection, and immersion treatments based on the MEC. Oral administration proved to be a safe method, yielding efficacy rates of 27.3% and 41.6% for 100 mg/kg and 200 mg/kg doses, respectively, in contrast to the immersion and injection methods, which induced symptoms of abnormal swimming, vomiting, and death. Biochemical analyses conducted to assess the safety of levamisole HCl revealed a transient, statistically significant elevation in the levels of glutamic oxaloacetic transaminase (GOT) and glutamic pyruvic transaminase (GPT) on day three post-administration at 20 °C. Following this, no substantial differences were observed. However, at 13 °C, the enzyme levels remained relatively consistent, emphasizing the role of water temperature conditions in influencing the action of levamisole HCl. Our research findings substantiate the efficacy of levamisole HCl against M. sebastis in Korean rockfish, underscoring its potential for safe oral administration. These results provide ...
    Keywords levamisole hydrochloride ; Sebastes schlegelii ; Microcotyle sebastis ; anthelmintic ; parasites ; monogenean ; Veterinary medicine ; SF600-1100 ; Zoology ; QL1-991
    Language English
    Publishing date 2023-05-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Recombinant protein embedded liposome on gold nanoparticle based on LSPR method to detect Corona virus

    Lina Kim / Seongjae Jo / Gyeong-Ji Kim / Kyung Ho Kim / Sung Eun Seo / Eunsu Ryu / Chan Jae Shin / Yu Kyung Kim / Jeong-Woo Choi / Oh Seok Kwon

    Nano Convergence, Vol 10, Iss 1, Pp 1-

    2023  Volume 10

    Abstract: Abstract Antibody sensor to detect viruses has been widely used but has problems such as the difficulty of right direction control of the receptor site on solid substrate, and long time and high cost for design and production of antibodies to new ... ...

    Abstract Abstract Antibody sensor to detect viruses has been widely used but has problems such as the difficulty of right direction control of the receptor site on solid substrate, and long time and high cost for design and production of antibodies to new emerging viruses. The virus detection sensor with a recombinant protein embedded liposome (R/Li) was newly developed to solve the above problems, in which R/Li was assembled on AuNPs (Au@R/Li) to increase the sensitivity using localized surface plasmon resonance (LSPR) method. Recombinant angiotensin-converting enzyme-2 (ACE2) was used as host receptors of SARS-CoV and SARS-CoV-2, and the direction of enzyme active site for virus attachment could be controlled by the integration with liposome. The recombinant protein embedded liposomes were assembled on AuNPs, and LSPR method was used for detection. With the sensor platform S1 protein of both viruses was detected with detection limit of 10 pg/ml and SARS-CoV-2 in clinical samples was detected with 10 ~ 35 Ct values. In the selectivity test, MERS-CoV did not show a signal due to no binding with Au@R/Li. The proposed sensor platform can be used as promising detection method with high sensitivity and selectivity for the early and simple diagnosis of new emerging viruses. Graphical Abstract
    Keywords Virus sensor ; Protein embedded liposome ; Recombinant protein ; SARS-CoV-2 detection ; LSPR ; Technology ; T ; Chemical technology ; TP1-1185 ; Biotechnology ; TP248.13-248.65 ; Science ; Q ; Physics ; QC1-999
    Subject code 500
    Language English
    Publishing date 2023-10-01T00:00:00Z
    Publisher SpringerOpen
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Clinical Assessment of Thermotherapy Applications during Hepatectomy and Laparotomy in Sturgeon ( Acipenser ruthenus )

    Gyoungsik Kang / Won-Sik Woo / Kyung-Ho Kim / Ha-Jeong Son / Min-Young Sohn / Hee Jeong Kong / Young-Ok Kim / Dong-Gyun Kim / Eun Mi Kim / Eun Soo Noh / Chan-II Park

    Veterinary Sciences, Vol 10, Iss 12, p

    Impact on Bioparameter Variations Based on Liver Condition

    2023  Volume 682

    Abstract: Surgical techniques are gaining attention for treating physical diseases in aquaculture and aquarium fish. Sturgeon is a suitable species for surgical experiments due to its industrial significance. Maintaining homeostasis is crucial during surgical ... ...

    Abstract Surgical techniques are gaining attention for treating physical diseases in aquaculture and aquarium fish. Sturgeon is a suitable species for surgical experiments due to its industrial significance. Maintaining homeostasis is crucial during surgical procedures, and the liver plays a major role in immune regulation. High temperature is suggested to improve physiological activity and wound healing. This study investigated differences in hepatectomy sturgeons’ tolerance and histopathological responses of internal organs. Moreover, this study investigated the effects of high temperatures on wound healing and hematopoietic recovery in fish undergoing surgical procedures. The liver condition was found to play a pivotal role in the analysis, and cortisol levels were affected by anesthesia. The results showed that high temperature facilitated hematopoietic recovery and wound healing, but excessive induction of physiological activity caused damage. Managing high temperatures and liver conditions induced a remarkable improvement in wound healing. However, anesthesia itself can be a significant stressor for fish, and wound healing requires a greater amount of energy. Further research is needed to understand the stress factors caused by surgical procedures and anesthesia and to promote animal welfare in fishery products.
    Keywords hepatectomy ; laparotomy ; sturgeon ; fish surgery ; sturgeon histology ; fish suturing ; Veterinary medicine ; SF600-1100
    Language English
    Publishing date 2023-12-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Chemical Design of Functional Polymer Structures for Biosensors

    Kyoung Min Lee / Kyung Ho Kim / Hyeonseok Yoon / Hyungwoo Kim

    Polymers, Vol 10, Iss 5, p

    From Nanoscale to Macroscale

    2018  Volume 551

    Abstract: Over the past decades, biosensors, a class of physicochemical detectors sensitive to biological analytes, have drawn increasing interest, particularly in light of growing concerns about human health. Functional polymeric materials have been widely ... ...

    Abstract Over the past decades, biosensors, a class of physicochemical detectors sensitive to biological analytes, have drawn increasing interest, particularly in light of growing concerns about human health. Functional polymeric materials have been widely researched for sensing applications because of their structural versatility and significant progress that has been made concerning their chemistry, as well as in the field of nanotechnology. Polymeric nanoparticles are conventionally used in sensing applications due to large surface area, which allows rapid and sensitive detection. On the macroscale, hydrogels are crucial materials for biosensing applications, being used in many wearable or implantable devices as a biocompatible platform. The performance of both hydrogels and nanoparticles, including sensitivity, response time, or reversibility, can be significantly altered and optimized by changing their chemical structures; this has encouraged us to overview and classify chemical design strategies. Here, we have organized this review into two main sections concerning the use of nanoparticles and hydrogels (as polymeric structures) for biosensors and described chemical approaches in relevant subcategories, which act as a guide for general synthetic strategies.
    Keywords functional polymers ; nanoparticles ; hydrogels ; chemical structures ; biosensor ; Organic chemistry ; QD241-441
    Subject code 540
    Language English
    Publishing date 2018-05-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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