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  1. Book ; Online: Urological Cancer 2022

    López, José I / López, José I / Manini, Claudia

    2023  

    Keywords Medicine ; Oncology ; high-risk prostate cancer ; androgen receptor axis ; castration resistance ; neuroendocrine carcinoma ; PARP inhibition ; immunotherapy ; cancer genome ; precision targeting ; robot-assisted partial nephrectomy ; renal cell carcinoma ; indocyanine green ; nephron sparing ; prostate cancer survivors ; follow-up care ; primary health care ; general practice ; process evaluation ; Consolidated Framework for Implementation Research ; prostate-specific membrane antigen positron-emission tomography ; multiparametric magnetic-resonance imaging ; primary diagnosis ; prostate cancer ; systematic review ; diagnosis ; PSMA ; PSA ; tumor ; PET scan ; bladder cancer ; bisphenol A ; bisphenol S ; energy metabolism ; migration ; proliferation ; carbon-ion radiotherapy ; elderly patients ; radiotherapy ; particle beam therapy ; life expectancy ; systemic immune-inflammation index ; Charlson comorbidity index ; CAPRA-S ; early survival ; male incontinence ; robotic prostatectomy ; clear cell renal cell carcinoma ; ferroptosis ; prognostic model ; TCGA ; E-MTAB-1980 ; GLS2 ; pazopanib ; real-world data ; non-interventional study ; time on drug ; nivolumab ; everolimus ; trial-eligibility ; ureteral neoplasms ; urinary bladder neoplasms ; ureteroscopy ; CNTF ; CNTFRα ; LNCaP ; 22Rv1 ; castration resistant ; castration sensitive ; STAT3 ; ERK ; MMP ; biomarker ; Gleason grade ; transforming growth factor-β family ; activin ; INHBA ; INHBB ; INHBC ; prostate-specific antigen ; false-positive results ; real world-data ; n/a
    Language English
    Size 1 electronic resource (238 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel
    Document type Book ; Online
    Note English
    HBZ-ID HT030376418
    ISBN 9783036569697 ; 3036569693
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online: Urological Cancer 2020

    López, José I. / López, José I.

    2021  

    Keywords Research & information: general ; Biology, life sciences ; renal cell carcinoma ; iron ; macrophages ; chelation therapy ; urothelial carcinoma ; transcriptome ; microtubule ; MAP1B ; prognosis ; KLF5 ; androgen receptor ; cell proliferation ; tumorigenesis ; prostate cancer ; precision medicine ; whole genome sequencing ; optical mapping ; therapy ; prostate carcinoma ; prostate mpMRI ; machine learning ; artificial intelligence ; deep learning ; neural network ; angiogenesis ; angiogenic growth factors ; antiangiogenic therapy ; renal tumors ; prevention ; α1-adrenoceptor antagonists ; anoikis ; vascularity ; research model ; oncogenes ; tumor suppressor genes ; MR-guided ; radiotherapy ; MRgRT ; stereotactic ablative radiotherapy ; stereotactic ablative radiation therapy (SABR) ; renal cell cancer ; RCC ; online adaptive ; [68Ga]Ga-PSMA PET/CT ; dual-time point imaging ; delayed imaging ; biphasic imaging ; lesion positivity rate ; CXCL9 ; PD1 ; PD-L1 ; stage T1 NMIBC ; prostatic neoplasms/mortality ; prostatic neoplasms/epidemiology ; SEER Program ; bladder cancer ; transurethral resection ; en-bloc resection ; CPT1A ; fatty acids ; serine ; androgen response ; ROS ; oxidative stress ; DONSON ; Downstream Neighbor of SON ; biomarker ; metastatic spread ; diagnosis ; differential diagnosis ; histopathology ; immunohistochemistry ; stroma signature ; patient-derived xenografts ; n/a
    Size 1 electronic resource (334 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel, Switzerland
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021289779
    ISBN 9783036502717 ; 3036502718
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book ; Online: Urological Cancer 2021

    López, José I. / López, José I. / Manini, Claudia

    2022  

    Keywords Research & information: general ; Chemistry ; bladder cancer ; radiotherapy ; radiosensitisation ; molecular subtypes ; preclinical studies ; bladder cancer cell lines ; latent cancer ; prostate cancer ; autopsy ; prognostic index ; prediction model ; mortality ; screening trial ; renal cell carcinoma ; PD-1 ; PD-L1 ; biomarkers ; immune checkpoint inhibitors ; prostatic neoplasms ; positron-emission tomography ; decision making ; tumor thrombus ; metastasectomy ; postoperative complications ; oncological outcomes ; radical cystectomy ; AHNAK2 ; prognosis ; dog ; comparative oncology ; inflammation ; prostatic atrophy ; preneoplastic lesion ; biomarker ; urine ; machine learning ; TRIPOD ; liquid biopsy ; glutaminase ; immunohistochemistry ; in situ methods ; prostate ; PSMA-RLT ; 177Lu-PSMA ; PSA ; mCRPC ; urinary bladder neoplasms ; Bacillus Calmette-Guérin (BCG) ; immunotherapy ; divergent differentiation ; variant morphology ; survival ; stereotactic body radiotherapy ; frail patients ; cancer ; metastasis ; genomic analysis ; microenvironment ; tumor ecology ; game theory ; fluorescence confocal microscopy ; prostate biopsy ; ablation margins ; focal therapy ; sphingosine 1-phosphate receptor 1 ; bladder carcinoma ; cell migration ; epithelial-mesenchymal transition ; FTY-720 ; OIP5 ; papillary renal cell carcinoma ; PLK1 ; tumorigenesis ; therapy ; image-guided ; magnetic resonance imaging ; ultrasonography ; biopsy ; abiraterone ; enzalutamide ; docetaxel ; novel hormonal therapies ; comparative effectiveness ; real-world treatment pattern ; metastatic prostate cancer ; epiplakin ; diagnosis ; advanced urothelial carcinoma ; immune checkpoint inhibitor ; prognostic ; tumour mutational board ; genomic signatures ; ctDNA ; inflammatory indices ; urothelial carcinoma ; frailty ; prognostic factor ; psoas muscle ; Hounsfield units ; n/a
    Language 0|e
    Size 1 electronic resource (328 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021610507
    ISBN 9783036530499 ; 3036530495
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Book ; Online: Clear Cell Renal Cell Carcinoma 2021-2022

    Manini, Claudia / López, José I. / López, José I.

    2022  

    Keywords Medicine ; Clinical & internal medicine ; clear cell renal cell carcinoma ; prognosis ; plasma ; PD-1 ; PD-L1 ; renal cell carcinoma ; immune checkpoint inhibitors ; immune related adverse events (irAEs) ; thyroid ; cutaneous ; biomarker ; DNA methylation ; epigenetics ; kidney ; hypoxia ; tumor microenvironment ; SCD-1 ; oleic acid ; renal cancer ; sunitinib ; resistance ; miRNA ; transcriptome ; pathway analysis ; nivolumab ; tissue slice culture ; PD1 ; T-cells ; metastatic clear cell renal cell carcinoma ; first-line treatment ; immunotherapy ; tyrosine kinase inhibitors ; combinations ; single-cell RNA sequencing ; immune landscape ; cancer immunotherapy ; intra-tumoral heterogeneity ; inter-tumoral heterogeneity ; inter-metastatic heterogeneity ; renal cell cancer ; treatment resistance ; angiogenesis ; adjuvant therapy ; prediction model ; prognostic factor ; clear cell kidney cancer ; radiogenomics ; radiomics ; machine learning ; gene expression ; cystic tumor ; imaging ; magnetic resonance ; surgery ; ddPCR ; circulating miRNA ; diagnosis ; malignancy ; histomorphological features ; PBRM1 ; immunohistochemistry ; architectural patterns ; endothelial cells ; translational ; immune checkpoint inhibitor ; responsiveness ; molecular features ; multisite tumor sampling ; intratumor heterogeneity ; clear-cell renal cell carcinoma ; disease progression ; prognostic factors ; biomarkers ; RNA sequencing ; n/a
    Language 0|e
    Size 1 electronic resource (342 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021621714
    ISBN 9783036555171 ; 303655517X
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  5. Book ; Online: Renal Cell Carcinoma

    López, José I

    2020  

    Keywords Biology, life sciences ; N-glycomapping ; n/a ; SMAD proteins ; patient survival ; pro-IL-1 ; survival prediction ; inflammation markers ; tumor migration ; prognostic factors ; practical approach ; circular RNAs in a clinico-genomic predictive model ; glycomarkers ; review ; nephrectomy ; uric acid ; VEGF inhibitors ; metabolic reprogramming ; collecting duct carcinoma ; curcumin ; metabolome profiling ; identification of circular RNAs ; IL-2 ; experimental validation of circular RNA ; Raf/MEK/ERK ; HOT ; PI3K/Akt/mTOR ; pentose phosphate pathway ; kidney cancer ; LOT ; mutation ; RCC ; polybromo-1 ; pale cell ; MMP-9 ; gene expression ; recurrence free survival ; chromosomal loss ; IL-1 ; chronic kidney disease ; glutathione transferase omega 2 ; label-free ; glutathione transferase omega 1 ; emerging entity ; copy number alteration ; FOXO3 ; predictive role ; tumor slice culture ; tyrosine kinase inhibitors ; PPP ; ESC ; CDKN1A expression ; metastasis ; PD-L1 ; diagnostic and prognostic markers ; EVI1 ; copy number loss ; RNA sequencing ; NK cells ; glutathione metabolism ; clear cell renal cell carcinoma ; renal cell cancer ; proliferation ; eosinophilic variant ; Xp11 translocation renal cell carcinoma ; prognosis ; invasion ; immune infiltration ; IL4R ; FISH ; 11) translocation renal cell carcinoma ; tumor microenvironment ; metabolome ; hyperosmolality ; toxicity ; ALK ; drug sensitivity ; t(6 ; copy number analysis ; urine ; genetic association ; polymorphism ; solute carrier proteins ; kidney ; metastatic ccRCC ; molecular genetic features ; recurrence-free survival ; chromophobe renal cell carcinoma ; unclassified renal tumor ; overall survival ; mTOR inhibitors ; mTOR ; JAK2 ; von Hippel-Lindau ; miR-155-5p ; glycoproteomics ; PBRM1 ; miR-133b ; survival ; TFE3 ; TFEB ; oncocytic renal tumor ; immune checkpoint inhibitors ; biomarker ; MMP10 ; TCGA ; ghrelin ; EMT like ; checkpoint inhibitors ; MiT family translocation renal cell carcinoma ; gene signature ; sarcomatoid ; transforming growth factor beta ; clear cell Renal Cell Carcinoma ; tumor adhesion ; renal cancer ; unclassified renal cell carcinoma ; Papillary renal cell carcinoma (pRCC) ; miR-146a-5p ; renal cell ; everolimus ; integrins ; cytoreductive nephrectomy ; immunotherapy ; predictive factors ; immunohistochemistry ; MTA2 ; IL13R?1 ; targeted therapy ; intratumour heterogeneity ; aurora A ; TCA cycle ; AMP-activated protein kinases ; cancer-specific survival ; programmed death-ligand 1 ; efficacy ; renal cell carcinoma ; anaplastic lymphoma kinase rearrangement ; TFEB-amplified renal cell carcinoma ; statins ; cancer immunotherapy ; microRNA ; new entity ; proteome profiling
    Language English
    Size 1 electronic resource (500 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Document type Book ; Online
    Note English
    HBZ-ID HT030648075
    ISBN 9783039286393 ; 3039286390
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  6. Article ; Online: Ecology and games in cancer: new insights into the disease.

    Manini, Claudia / López, José I

    Pathologica

    2022  Volume 114, Issue 5, Page(s) 347–351

    MeSH term(s) Humans ; Ecology ; Neoplasms/diagnosis
    Language English
    Publishing date 2022-08-10
    Publishing country Italy
    Document type Editorial
    ZDB-ID 418229-7
    ISSN 1591-951X ; 0031-2983
    ISSN (online) 1591-951X
    ISSN 0031-2983
    DOI 10.32074/1591-951X-798
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 369: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  7. Article: Pathology and the evolutionary dynamics of clear cell renal cell carcinoma.

    Manini, Claudia / López, José I

    Translational oncology

    2022  Volume 27, Page(s) 101601

    Abstract: Cancer is an ecosystem whose intrinsic mechanisms do not show up under the microscope of pathologists. However, the information provided by pathologists is absolutely necessary for the correct implementation of personalized treatments. This short paper ... ...

    Abstract Cancer is an ecosystem whose intrinsic mechanisms do not show up under the microscope of pathologists. However, the information provided by pathologists is absolutely necessary for the correct implementation of personalized treatments. This short paper seeks to analyze this apparent paradox, i.e. static snapshots for making crucial decisions in essentially dynamic diseases, taking clear cell renal cell carcinoma as a paradigmatic example of tumor variability. We seek to call the attention of pathologists and other cancer-related medical specialists to extend knowledge of the evolutionary features of the disease to help obtain a better understanding of why cancer behaves as it does.
    Language English
    Publishing date 2022-12-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2443840-6
    ISSN 1936-5233
    ISSN 1936-5233
    DOI 10.1016/j.tranon.2022.101601
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Updating Clear Cell Renal Cell Carcinoma (a Tribute to Prof. Ondrej Hes).

    Manini, Claudia / López, José I

    Cancers

    2022  Volume 14, Issue 16

    Abstract: This Special Issue provides an insight into critical issues concerning clear cell renal cell carcinomas (CCRCCs), reflecting the recent level of intricacy reached by renal oncology [ ... ]. ...

    Abstract This Special Issue provides an insight into critical issues concerning clear cell renal cell carcinomas (CCRCCs), reflecting the recent level of intricacy reached by renal oncology [...].
    Language English
    Publishing date 2022-08-18
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers14163990
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Clear Cell Renal Cell Carcinoma: A Test Bench for Investigating Tumor Complexity.

    Manini, Claudia / López-Fernández, Estíbaliz / Larrinaga, Gorka / López, José I

    Cancers

    2024  Volume 16, Issue 4

    Abstract: Clear cell renal cell carcinoma (CCRCC), by far the most common renal cancer subtype, is an aggressive tumor variant, serving in recent years as a prolific test bench in cancer research [ ... ]. ...

    Abstract Clear cell renal cell carcinoma (CCRCC), by far the most common renal cancer subtype, is an aggressive tumor variant, serving in recent years as a prolific test bench in cancer research [...].
    Language English
    Publishing date 2024-02-19
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers16040829
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Insights into Urological Cancer.

    Manini, Claudia / López, José I

    Cancers

    2021  Volume 13, Issue 2

    Abstract: The year the Covid-19 pandemic appeared has been quite prolific in urological cancer research, and the collection of articles, perspectives, and reviews on renal, prostate, and urinary tract tumors merged in ... ...

    Abstract The year the Covid-19 pandemic appeared has been quite prolific in urological cancer research, and the collection of articles, perspectives, and reviews on renal, prostate, and urinary tract tumors merged in this
    Language English
    Publishing date 2021-01-08
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers13020204
    Database MEDical Literature Analysis and Retrieval System OnLINE

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