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  1. Article ; Online: Exopolysaccharides from Microalgae and Cyanobacteria: Diversity of Strains, Production Strategies, and Applications.

    Laroche, Céline

    Marine drugs

    2022  Volume 20, Issue 5

    Abstract: Microalgae and cyanobacteria are photosynthetic organisms that can produce/accumulate biomolecules with industrial interest. Among these molecules, EPSs are macromolecular polysaccharidic compounds that present biological activities and physico-chemical ... ...

    Abstract Microalgae and cyanobacteria are photosynthetic organisms that can produce/accumulate biomolecules with industrial interest. Among these molecules, EPSs are macromolecular polysaccharidic compounds that present biological activities and physico-chemical properties, allowing to consider their valorization in diverse commercial markets, such as cosmetic, therapeutic, nutraceutic, or hydrocolloids areas. The number of microalgae and cyanobacteria strains described to produce such EPSs has increased in recent years as, among the 256 producing strains gathered in this review, 86 were published in the last 10 years (~33%). Moreover, with the rise of research on microalgae EPSs, a variety of monosaccharides compositions have been discovered, highlighting the versatility of these organisms. If some production strategies can be applied to increase EPS production yields, it appears that case by case studies are needed to promote EPS synthesis by a strain, as many responses exist. This paper proposes an up-to-date state of the art of the diversity of microalgae and cyanobacteria EPS-producing strains, associated to the variability of compositions. The strategies for the production and extraction of the polymers are also discussed. Finally, an overview of the biological activities and physico-chemical properties allow one to consider their use on several commercial markets.
    MeSH term(s) Cyanobacteria ; Microalgae/chemistry ; Photosynthesis
    Language English
    Publishing date 2022-05-21
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2175190-0
    ISSN 1660-3397 ; 1660-3397
    ISSN (online) 1660-3397
    ISSN 1660-3397
    DOI 10.3390/md20050336
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Immune monitoring in pediatric kidney transplant.

    Laroche, Camille / Engen, Rachel M

    Pediatric transplantation

    2024  Volume 28, Issue 4, Page(s) e14785

    Abstract: Background: Long-term outcomes in pediatric kidney transplantation remain suboptimal, largely related to chronic rejection. Creatinine is a late marker of renal injury, and more sensitive, early markers of allograft injury are an active area of current ... ...

    Abstract Background: Long-term outcomes in pediatric kidney transplantation remain suboptimal, largely related to chronic rejection. Creatinine is a late marker of renal injury, and more sensitive, early markers of allograft injury are an active area of current research.
    Methods: This is an educational review summarizing existing strategies for monitoring for rejection in kidney transplant recipients.
    Results: We summarize supporting currently available clinical tests, including surveillance biopsy, donor specific antibodies, and donor-derived cell free DNA, as well as the potential limitations of these studies. In addition, we review the current avenues of active research, including transcriptomics, proteomics, metabolomics, and torque tenovirus levels.
    Conclusion: Advancing the use of noninvasive immune monitoring will depend on well-designed multicenter trials that include patients with stable graft function, include biopsy results on all patients, and can demonstrate both association with a patient-relevant clinical endpoint such as graft survival or change in glomerular filtration rate and a potential timepoint for intervention.
    MeSH term(s) Humans ; Kidney Transplantation ; Graft Rejection/immunology ; Child ; Monitoring, Immunologic/methods ; Biomarkers/metabolism ; Biopsy ; Graft Survival/immunology
    Language English
    Publishing date 2024-05-20
    Publishing country Denmark
    Document type Journal Article ; Review
    ZDB-ID 1390284-2
    ISSN 1399-3046 ; 1397-3142
    ISSN (online) 1399-3046
    ISSN 1397-3142
    DOI 10.1111/petr.14785
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Carfilzomib: Looking for 'The Holy Grail' to treat antibody-mediated rejection.

    Laroche, Camille / Marks, Stephen D

    Pediatric transplantation

    2023  Volume 27, Issue 7, Page(s) e14533

    Language English
    Publishing date 2023-05-02
    Publishing country Denmark
    Document type Editorial
    ZDB-ID 1390284-2
    ISSN 1399-3046 ; 1397-3142
    ISSN (online) 1399-3046
    ISSN 1397-3142
    DOI 10.1111/petr.14533
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Chemical characterization of polysaccharides from Gracilaria gracilis from Bizerte (Tunisia).

    Yahyaoui, K / Traikia, M / Rihouey, C / Picton, L / Gardarin, C / Ksouri, W Megdiche / Laroche, C

    International journal of biological macromolecules

    2024  Volume 266, Issue Pt 2, Page(s) 131127

    Abstract: Polysaccharides were extracted from Gracilaria gracilis collected from Manzel Jemil Lake in Bizerte Tunisia, with two different solvents (water and NaOH 0.3 M). Different assays were performed on samples (total sugars, neutral sugars, uronic acids, ... ...

    Abstract Polysaccharides were extracted from Gracilaria gracilis collected from Manzel Jemil Lake in Bizerte Tunisia, with two different solvents (water and NaOH 0.3 M). Different assays were performed on samples (total sugars, neutral sugars, uronic acids, anhydrogalactose, proteins, sulphates, pyruvates), followed by high performance anion-exchange chromatography (HPAEC) to observe the monosaccharide composition, high pressure size exclusion chromatography with multi-angle laser light scattering (HPSEC-MALS) to obtain the molecular mass, Fourier transform infrared spectroscopy (FTIR), and 1D and 2D nuclear magnetic resonance (NMR) to access to structural data. Results have shown that the polysaccharide extracted from Gracilaria gracilis collected from Manzel Jemil Lake in Bizerte Tunisia, is of agar type but with high molecular mass and some original structural features. Hence, the sample was found to contain 9 % of pyruvate groups and is partly sulphated at the C4 of β-d-galactose and methylated on C2 of anhydro-α-l-galactose. The polymer from G. gracilis from Bizerte thus presents a never described structure that could be interesting for further rheological or biological activities applications.
    MeSH term(s) Gracilaria/chemistry ; Tunisia ; Polysaccharides/chemistry ; Polysaccharides/isolation & purification ; Molecular Weight ; Monosaccharides/analysis ; Monosaccharides/chemistry ; Spectroscopy, Fourier Transform Infrared ; Magnetic Resonance Spectroscopy
    Chemical Substances Polysaccharides ; Monosaccharides
    Language English
    Publishing date 2024-03-26
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2024.131127
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Optimal transplantation options for children with Schimke immuno-osseous dysplasia.

    Laroche, Camille / Lucchini, Giovanna / Worth, Austen / Marks, Stephen D

    Pediatric transplantation

    2023  Volume 28, Issue 1, Page(s) e14616

    MeSH term(s) Child ; Humans ; Nephrotic Syndrome/surgery ; Primary Immunodeficiency Diseases/surgery ; Osteochondrodysplasias/surgery ; Arteriosclerosis ; Pulmonary Embolism ; Immunologic Deficiency Syndromes/surgery
    Language English
    Publishing date 2023-10-03
    Publishing country Denmark
    Document type Editorial
    ZDB-ID 1390284-2
    ISSN 1399-3046 ; 1397-3142
    ISSN (online) 1399-3046
    ISSN 1397-3142
    DOI 10.1111/petr.14616
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Exploring the Diversity of Red Microalgae for Exopolysaccharide Production.

    Borjas Esqueda, Aldo / Gardarin, Christine / Laroche, Céline

    Marine drugs

    2022  Volume 20, Issue 4

    Abstract: Microalgae constitute a remarkable biological diversity but a limited number of them have been the object of study for their ability to produce exoplysaccharides (EPS). Among them, the red marine ... ...

    Abstract Microalgae constitute a remarkable biological diversity but a limited number of them have been the object of study for their ability to produce exoplysaccharides (EPS). Among them, the red marine microalgae
    MeSH term(s) Culture Media/chemistry ; Microalgae/chemistry ; Polysaccharides, Bacterial/metabolism ; Porphyridium/metabolism ; Rhodophyta ; Sulfates/chemistry
    Chemical Substances Culture Media ; Polysaccharides, Bacterial ; Sulfates
    Language English
    Publishing date 2022-03-31
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2175190-0
    ISSN 1660-3397 ; 1660-3397
    ISSN (online) 1660-3397
    ISSN 1660-3397
    DOI 10.3390/md20040246
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book ; Online: Fast Diffusion EM

    Laroche, Charles / Almansa, Andrés / Coupete, Eva

    a diffusion model for blind inverse problems with application to deconvolution

    2023  

    Abstract: Using diffusion models to solve inverse problems is a growing field of research. Current methods assume the degradation to be known and provide impressive results in terms of restoration quality and diversity. In this work, we leverage the efficiency of ... ...

    Abstract Using diffusion models to solve inverse problems is a growing field of research. Current methods assume the degradation to be known and provide impressive results in terms of restoration quality and diversity. In this work, we leverage the efficiency of those models to jointly estimate the restored image and unknown parameters of the degradation model such as blur kernel. In particular, we designed an algorithm based on the well-known Expectation-Minimization (EM) estimation method and diffusion models. Our method alternates between approximating the expected log-likelihood of the inverse problem using samples drawn from a diffusion model and a maximization step to estimate unknown model parameters. For the maximization step, we also introduce a novel blur kernel regularization based on a Plug \& Play denoiser. Diffusion models are long to run, thus we provide a fast version of our algorithm. Extensive experiments on blind image deblurring demonstrate the effectiveness of our method when compared to other state-of-the-art approaches.
    Keywords Computer Science - Computer Vision and Pattern Recognition
    Subject code 006
    Publishing date 2023-09-01
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: The treatment of nephritis; action of antibiotics.

    LAROCHE, C

    Bulletin medical

    2008  Volume 62, Issue 8, Page(s) 113–116

    Title translation Le traitement de néphrites; action des antibiotiques.
    MeSH term(s) Nephritis/therapy
    Language French
    Publishing date 2008-06-20
    Publishing country France
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Monovalent and bivalent cations exchange isotherms for faujasites X and Y.

    Khabzina, Y / Laroche, C / Pagis, C / Farrusseng, D

    Physical chemistry chemical physics : PCCP

    2017  Volume 19, Issue 26, Page(s) 17242–17249

    Abstract: This study addresses the modeling of exchange isotherms for faujasite-type zeolites X and Y with ... ...

    Abstract This study addresses the modeling of exchange isotherms for faujasite-type zeolites X and Y with K
    Language English
    Publishing date 2017-07-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 1476244-4
    ISSN 1463-9084 ; 1463-9076
    ISSN (online) 1463-9084
    ISSN 1463-9076
    DOI 10.1039/c7cp02051a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Pressure dependence of the electrical transport in granular materials.

    Creyssels, M / Laroche, C / Falcon, E / Castaing, B

    The European physical journal. E, Soft matter

    2017  Volume 40, Issue 5, Page(s) 56

    Abstract: We report on systematic measurements of the electrical resistance of one- and three-dimensional (1D and 3D) metallic and oxidized granular materials under uni-axial compression. Whatever the dimension of the packing, the resistance follows a power law ... ...

    Abstract We report on systematic measurements of the electrical resistance of one- and three-dimensional (1D and 3D) metallic and oxidized granular materials under uni-axial compression. Whatever the dimension of the packing, the resistance follows a power law versus the pressure ([Formula: see text]), with an exponent [Formula: see text] much larger than the ones expected either with elastic or plastic contact between the grains. A simple model based on a statistical description of the micro-contacts between two grains is proposed. It shows that the strong dependence of the resistance on the pressure applied to the granular media is a consequence of large variabilities and heterogeneities present at the contact surface between two grains. Then, the effect of the three-dimensional structure of the packing is investigated using a renormalization process. This allows to reconcile two extreme approaches of a 3D lattice of widely distributed resistances: the effective medium and the percolation theories.
    Language English
    Publishing date 2017-05
    Publishing country France
    Document type Journal Article
    ZDB-ID 2004003-9
    ISSN 1292-895X ; 1292-8941
    ISSN (online) 1292-895X
    ISSN 1292-8941
    DOI 10.1140/epje/i2017-11543-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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