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  1. Article ; Online: Transvaginal repair of isthmocele after cesarean scar pregnancy.

    Barba, Marta / Cola, Alice / Passoni, Paolo / La Milia, Laura / De Vicari, Desirèe / Frigerio, Matteo

    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

    2023  Volume 162, Issue 2, Page(s) 775–776

    MeSH term(s) Pregnancy ; Female ; Humans ; Cicatrix/surgery ; Cicatrix/pathology ; Pregnancy, Ectopic/diagnostic imaging ; Pregnancy, Ectopic/etiology ; Pregnancy, Ectopic/surgery ; Hysteroscopy ; Laparoscopy
    Language English
    Publishing date 2023-06-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80149-5
    ISSN 1879-3479 ; 0020-7292
    ISSN (online) 1879-3479
    ISSN 0020-7292
    DOI 10.1002/ijgo.14900
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Splenic artery aneurysm in obstetrical patients: A series of four cases with different clinical presentation and outcome.

    Ornaghi, Sara / Crippa, Isabella / Di Nicola, Sara / Giardini, Valentina / La Milia, Laura / Locatelli, Luca / Corso, Rocco / Roncaglia, Nadia / Vergani, Patrizia

    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

    2022  Volume 159, Issue 2, Page(s) 474–479

    Abstract: Objective: To describe four consecutive cases of splenic artery aneurysm (SAA) with different clinical patterns of presentation among obstetrical patients.: Methods: A series of four cases of SAA diagnosed in pregnant or postpartum women at our ... ...

    Abstract Objective: To describe four consecutive cases of splenic artery aneurysm (SAA) with different clinical patterns of presentation among obstetrical patients.
    Methods: A series of four cases of SAA diagnosed in pregnant or postpartum women at our University center between January 1998 and December 2020. Clinical and radiologic data were retrospectively obtained by reviewing paper and electronic medical records after acquiring patient's consent.
    Results: One case was completely asymptomatic and incidentally identified at the beginning of pregnancy, thus allowing for multidisciplinary treatment. The other three cases were unknown: two manifested with maternal collapse due to aneurysm rupture in the third trimester of gestation, whereas one presented with acute abdominal pain during the postpartum period and was successfully managed before rupture occurred.
    Conclusion: Although extremely rare, SAA rupture in obstetrical patients can be associated with dramatic consequences. Early suspicion and prompt intervention are essential to avoid fatal outcomes, so promotion of knowledge of all the potential clinical patterns of presentation of SAA rupture among obstetrical patients is mandatory.
    MeSH term(s) Aneurysm, Ruptured/complications ; Aneurysm, Ruptured/diagnostic imaging ; Female ; Humans ; Pregnancy ; Pregnancy Complications, Cardiovascular/diagnostic imaging ; Pregnancy Complications, Cardiovascular/therapy ; Pregnancy Trimester, Third ; Retrospective Studies ; Splenic Artery/diagnostic imaging
    Language English
    Publishing date 2022-03-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80149-5
    ISSN 1879-3479 ; 0020-7292
    ISSN (online) 1879-3479
    ISSN 0020-7292
    DOI 10.1002/ijgo.14133
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Feasibility of CPAP application and variables related to worsening of respiratory failure in pregnant women with SARS-CoV-2 pneumonia: Experience of a tertiary care centre.

    Faverio, Paola / Ornaghi, Sara / Stainer, Anna / Invernizzi, Francesca / Borelli, Mara / Brunetti, Federica / La Milia, Laura / Paolini, Valentina / Rona, Roberto / Foti, Giuseppe / Luppi, Fabrizio / Vergani, Patrizia / Pesci, Alberto

    PloS one

    2021  Volume 16, Issue 10, Page(s) e0258754

    Abstract: Continuous positive airway pressure (CPAP) has been successfully applied to patients with COVID-19 to prevent endotracheal intubation. However, experience of CPAP application in pregnant women with acute respiratory failure (ARF) due to SARS-CoV-2 ... ...

    Abstract Continuous positive airway pressure (CPAP) has been successfully applied to patients with COVID-19 to prevent endotracheal intubation. However, experience of CPAP application in pregnant women with acute respiratory failure (ARF) due to SARS-CoV-2 pneumonia is scarce. This study aimed to describe the natural history and outcome of ARF in a cohort of pregnant women with SARS-CoV-2 pneumonia, focusing on the feasibility of helmet CPAP (h-CPAP) application and the variables related to ARF worsening. A retrospective, observational study enrolling 41 consecutive pregnant women hospitalised for SARS-CoV-2 pneumonia in a tertiary care center between March 2020 and March 2021. h-CPAP was applied if arterial partial pressure of oxygen to fraction of inspired oxygen ratio (PaO2/FiO2) was inferior to 200 and/or patients had respiratory distress despite adequate oxygen supplementation. Characteristics of patients requiring h-CPAP vs those in room air or oxygen only were compared. Twenty-seven (66%) patients showed hypoxemic ARF requiring oxygen supplementation and h-CPAP was needed in 10 cases (24%). PaO2/FiO2 was significantly improved during h-CPAP application. The device was well-tolerated in all cases with no adverse events. Higher serum C reactive protein and more extensive (≥3 lobes) involvement at chest X-ray upon admission were observed in the h-CPAP group. Assessment of temporal distribution of cases showed a substantially increased rate of CPAP requirement during the third pandemic wave (January-March 2021). In conclusion, h-CPAP was feasible, safe, well-tolerated and improved oxygenation in pregnant women with moderate-to-severe ARF due to SARS-CoV-2 pneumonia. Moderate-to-severe ARF was more frequently observed during the third pandemic wave.
    MeSH term(s) Acute Disease ; Adult ; COVID-19/blood ; COVID-19/therapy ; Continuous Positive Airway Pressure ; Female ; Humans ; Oxygen/administration & dosage ; Oxygen/blood ; Pregnancy ; Pregnancy Complications, Infectious/blood ; Pregnancy Complications, Infectious/therapy ; Protein C/metabolism ; Respiratory Insufficiency/blood ; Respiratory Insufficiency/therapy ; Retrospective Studies ; SARS-CoV-2/metabolism ; Tertiary Care Centers
    Chemical Substances Protein C ; Oxygen (S88TT14065)
    Language English
    Publishing date 2021-10-19
    Publishing country United States
    Document type Clinical Trial ; Journal Article
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0258754
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Performance of an extended triage questionnaire to detect suspected cases of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection in obstetric patients: Experience from two large teaching hospitals in Lombardy, Northern Italy.

    Ornaghi, Sara / Callegari, Clelia / Milazzo, Roberta / La Milia, Laura / Brunetti, Federica / Lubrano, Chiara / Tasca, Chiara / Livio, Stefania / Savasi, Valeria Maria / Cetin, Irene / Vergani, Patrizia

    PloS one

    2020  Volume 15, Issue 9, Page(s) e0239173

    Abstract: Objectives: 1. To assess the performance of an extended questionnaire in identifying cases of SARS-CoV-2 infection among obstetric patients. 2. To evaluate the rate of infection among healthcare workers involved in women's care.: Study design: A ... ...

    Abstract Objectives: 1. To assess the performance of an extended questionnaire in identifying cases of SARS-CoV-2 infection among obstetric patients. 2. To evaluate the rate of infection among healthcare workers involved in women's care.
    Study design: A prospective cohort study of obstetric patients admitted to MBBM Foundation and Buzzi Hospital (Lombardy, Northern Italy) from March 16th to May 22nd, 2020. Women were screened on admission by a questionnaire investigating major and minor symptoms of infection and high-risk contacts in the last 14 days. SARS-CoV-2 assessment was performed by RT-PCR on nasopharyngeal swabs. Till April 7th, a targeted SARS-CoV-2 testing triggered by a positive questionnaire was used; from April 8th, a universal testing approach was implemented.
    Results: There were 1,177 women screened by the questionnaire, which yielded a positive result in 130 (11.0%) cases. SARS-CoV-2 RT-PCR was performed in 865 (73.5%) patients, identifying 51 (5.9%) infections. During the first period, there were 29 infected mothers, 4 (13.8%) of whom had a negative questionnaire. After universal testing implementation, there were 22 (3%, 95% CI 1.94% - 4.04%) infected mothers, 13 (59.1%) of whom had a negative questionnaire; rate of infection among asymptomatic women was 1.9%. Six of the 17 SARS-CoV-2-positive women with a negative questionnaire reported symptoms more than 14 but within 30 days before admission. Isolated olfactory or taste disorders were identified in 15.7% of infected patients. Rate of infection among healthcare workers was 5.8%.
    Conclusions: An exhaustive triage questionnaire can effectively discriminate women at low risk of SARS-CoV-2 infection in the context of a targeted and a universal viral testing approach. In 15.7% of infected women, correct classification as a suspected case of infection was due to investigation of olfactory and taste disorders. Extension of the assessed time-frame to 30 days may be worth considering to increase the questionnaire's performance.
    MeSH term(s) Adult ; Asymptomatic Diseases/epidemiology ; Betacoronavirus/genetics ; Betacoronavirus/isolation & purification ; COVID-19 ; Coronavirus Infections/diagnosis ; Coronavirus Infections/epidemiology ; Coronavirus Infections/virology ; Female ; Health Personnel/statistics & numerical data ; Hospitals, Teaching ; Humans ; Italy/epidemiology ; Nasopharynx/virology ; Pandemics ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/virology ; Prospective Studies ; RNA, Viral/metabolism ; Reverse Transcriptase Polymerase Chain Reaction ; SARS-CoV-2 ; Surveys and Questionnaires ; Taste Disorders/diagnosis ; Taste Disorders/epidemiology ; Taste Disorders/etiology ; Triage
    Chemical Substances RNA, Viral
    Keywords covid19
    Language English
    Publishing date 2020-09-15
    Publishing country United States
    Document type Journal Article
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0239173
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Performance of an extended triage questionnaire to detect suspected cases of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection in obstetric patients

    Ornaghi, Sara / Callegari, Clelia / Milazzo, Roberta / La Milia, Laura / Brunetti, Federica / Lubrano, Chiara / Tasca, Chiara / Livio, Stefania / Savasi, Valeria Maria / Cetin, Irene / Vergani, Patrizia

    PLOS ONE

    Experience from two large teaching hospitals in Lombardy, Northern Italy

    2020  Volume 15, Issue 9, Page(s) e0239173

    Keywords General Biochemistry, Genetics and Molecular Biology ; General Agricultural and Biological Sciences ; General Medicine ; covid19
    Language English
    Publisher Public Library of Science (PLoS)
    Publishing country us
    Document type Article ; Online
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0239173
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article: Performance of an extended triage questionnaire to detect suspected cases of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection in obstetric patients: Experience from two large teaching hospitals in Lombardy, Northern Italy

    Ornaghi, Sara / Callegari, Clelia / Milazzo, Roberta / La Milia, Laura / Brunetti, Federica / Lubrano, Chiara / Tasca, Chiara / Livio, Stefania / Savasi, Valeria Maria / Cetin, Irene / Vergani, Patrizia

    PLoS One

    Abstract: OBJECTIVES: 1. To assess the performance of an extended questionnaire in identifying cases of SARS-CoV-2 infection among obstetric patients. 2. To evaluate the rate of infection among healthcare workers involved in women's care. STUDY DESIGN: A ... ...

    Abstract OBJECTIVES: 1. To assess the performance of an extended questionnaire in identifying cases of SARS-CoV-2 infection among obstetric patients. 2. To evaluate the rate of infection among healthcare workers involved in women's care. STUDY DESIGN: A prospective cohort study of obstetric patients admitted to MBBM Foundation and Buzzi Hospital (Lombardy, Northern Italy) from March 16th to May 22nd, 2020. Women were screened on admission by a questionnaire investigating major and minor symptoms of infection and high-risk contacts in the last 14 days. SARS-CoV-2 assessment was performed by RT-PCR on nasopharyngeal swabs. Till April 7th, a targeted SARS-CoV-2 testing triggered by a positive questionnaire was used; from April 8th, a universal testing approach was implemented. RESULTS: There were 1,177 women screened by the questionnaire, which yielded a positive result in 130 (11.0%) cases. SARS-CoV-2 RT-PCR was performed in 865 (73.5%) patients, identifying 51 (5.9%) infections. During the first period, there were 29 infected mothers, 4 (13.8%) of whom had a negative questionnaire. After universal testing implementation, there were 22 (3%, 95% CI 1.94% - 4.04%) infected mothers, 13 (59.1%) of whom had a negative questionnaire; rate of infection among asymptomatic women was 1.9%. Six of the 17 SARS-CoV-2-positive women with a negative questionnaire reported symptoms more than 14 but within 30 days before admission. Isolated olfactory or taste disorders were identified in 15.7% of infected patients. Rate of infection among healthcare workers was 5.8%. CONCLUSIONS: An exhaustive triage questionnaire can effectively discriminate women at low risk of SARS-CoV-2 infection in the context of a targeted and a universal viral testing approach. In 15.7% of infected women, correct classification as a suspected case of infection was due to investigation of olfactory and taste disorders. Extension of the assessed time-frame to 30 days may be worth considering to increase the questionnaire's performance.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #768840
    Database COVID19

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