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Article ; Online: Complex trans-ridge normal faults controlling large earthquakes.

Bello, Simone / Lavecchia, Giusy / Andrenacci, Carlo / Ercoli, Maurizio / Cirillo, Daniele / Carboni, Filippo / Barchi, Massimiliano R / Brozzetti, Francesco

Scientific reports

2022 Volume 12, Issue 1, Page(s) 10676

Abstract: Studying faults capable of releasing moderate-to-strong earthquakes is fundamental for seismic hazard studies, especially in a territory that was subject to the strongest peninsular Italy earthquake (1857, ... ...

Abstract	Studying faults capable of releasing moderate-to-strong earthquakes is fundamental for seismic hazard studies, especially in a territory that was subject to the strongest peninsular Italy earthquake (1857, M
Language	English
Publishing date	2022-06-23
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-022-14406-4
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Article ; Online: QUaternary fault strain INdicators database - QUIN 1.0 - first release from the Apennines of central Italy.

Lavecchia, Giusy / Bello, Simone / Andrenacci, Carlo / Cirillo, Daniele / Ferrarini, Federica / Vicentini, Noemi / de Nardis, Rita / Roberts, Gerald / Brozzetti, Francesco

Scientific data

2022 Volume 9, Issue 1, Page(s) 204

Abstract: We present QUIN, a "QUaternary fault strain INdicators database", designed to integrate and unify published and unpublished local-scale geological information and derive strain parameters for structural and seismotectonic analyses. It provides data on ... ...

Abstract	We present QUIN, a "QUaternary fault strain INdicators database", designed to integrate and unify published and unpublished local-scale geological information and derive strain parameters for structural and seismotectonic analyses. It provides data on 3339 Fault Striation Pairs (FSP; fault plane and slickenline), distributed within 455 survey sites. These are exposed along the intra-Apennine Quaternary extensional faults of Central Italy. The area covers an extent of ~550 km in a NW-SE direction. We give information on FSP location, attitude and kinematics, and deformation axes. We also provide an original shapefile of the faults hosting the FSP. A large amount of homogeneously distributed Quaternary fault/slip data help to clarify and implement the contemporary geometric and kinematic deformation pattern of Central Italy that appears scattered and incomplete whenever exclusively derived from earthquake data. The high-density of structural data can help investigate stress pattern heterogeneities at local scales, with relevance for new generations of hazard assessment evaluation and a better understanding of rupture propagation and related barriers.
Language	English
Publishing date	2022-05-12
Publishing country	England
Document type	Journal Article
ZDB-ID	2775191-0
ISSN	2052-4463 ; 2052-4463
ISSN (online)	2052-4463
ISSN	2052-4463
DOI	10.1038/s41597-022-01311-8
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Article ; Online: Lithospheric double shear zone unveiled by microseismicity in a region of slow deformation.

de Nardis, Rita / Pandolfi, Claudia / Cattaneo, Marco / Monachesi, Giancarlo / Cirillo, Daniele / Ferrarini, Federica / Bello, Simone / Brozzetti, Francesco / Lavecchia, Giusy

Scientific reports

2022 Volume 12, Issue 1, Page(s) 21066

Abstract: The deformation style of the continental lithosphere is a relevant issue for geodynamics and seismic hazard perspectives. Here we show the first evidence of two well-distinct low-angle and SW-dipping individual reverse shear zones of the Italian Outer ... ...

Abstract	The deformation style of the continental lithosphere is a relevant issue for geodynamics and seismic hazard perspectives. Here we show the first evidence of two well-distinct low-angle and SW-dipping individual reverse shear zones of the Italian Outer Thrust System in Central Italy. One corresponds to the down-dip prosecution of the Adriatic Basal Thrust with its major splay and the other to a hidden independent structure, illuminated at a depth between 25 and 60 km, for an along-strike extent of ~ 150 km. Combining geological information with high-quality seismological data, we unveil this novel configuration and reconstruct a detailed 3D geometric and kinematic fault model of the compressional system, active at upper crust to upper mantle depths. In addition, we report evidence of coexisting deformation volumes undergoing well-distinguished stress fields at different lithospheric depths. These results provide fundamental constraints for a forthcoming discussion on the Apennine fold-and-thrust system's geodynamic context as a shallow subduction zone or an intra-continental lithosphere shear zone.
Language	English
Publishing date	2022-12-06
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-022-24903-1
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Article ; Online: High-resolution surface faulting from the 1983 Idaho Lost River Fault M

Bello, Simone / Scott, Chelsea P / Ferrarini, Federica / Brozzetti, Francesco / Scott, Tyler / Cirillo, Daniele / de Nardis, Rita / Arrowsmith, J Ramón / Lavecchia, Giusy

Scientific data

2021 Volume 8, Issue 1, Page(s) 68

Abstract: We present high-resolution mapping and surface faulting measurements along the Lost River fault (Idaho-USA), a normal fault activated in the 1983 ( ... ...

Abstract	We present high-resolution mapping and surface faulting measurements along the Lost River fault (Idaho-USA), a normal fault activated in the 1983 (M
Language	English
Publishing date	2021-02-26
Publishing country	England
Document type	Journal Article
ZDB-ID	2775191-0
ISSN	2052-4463 ; 2052-4463
ISSN (online)	2052-4463
ISSN	2052-4463
DOI	10.1038/s41597-021-00838-6
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Article ; Online: Iodide mumps: sonographic appearance.

Greco, S / Centenaro, R / Lavecchia, G / Rossi, F

Journal of clinical ultrasound : JCU

2010 Volume 38, Issue 8, Page(s) 438–439

Abstract: Swelling of the salivary glands occurring after injection of iodine-based contrast agent is a rare late adverse reaction. Only a few cases in the literature illustrate such ultrasound findings. ...

Abstract	Swelling of the salivary glands occurring after injection of iodine-based contrast agent is a rare late adverse reaction. Only a few cases in the literature illustrate such ultrasound findings.
MeSH term(s)	Adult ; Contrast Media/adverse effects ; Humans ; Iodides/adverse effects ; Salivary Gland Diseases/chemically induced ; Salivary Gland Diseases/diagnostic imaging ; Salivary Glands/diagnostic imaging ; Ultrasonography
Chemical Substances	Contrast Media ; Iodides
Language	English
Publishing date	2010-10
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	189393-2
ISSN	1097-0096 ; 0091-2751
ISSN (online)	1097-0096
ISSN	0091-2751
DOI	10.1002/jcu.20701
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Article ; Online: QUIN 2.0 - new release of the QUaternary fault strain INdicators database from the Southern Apennines of Italy.

Lavecchia, Giusy / Bello, Simone / Andrenacci, Carlo / Cirillo, Daniele / Pietrolungo, Federico / Talone, Donato / Ferrarini, Federica / de Nardis, Rita / Galli, Paolo / Faure Walker, Joanna / Sgambato, Claudia / Menichetti, Marco / Monaco, Carmelo / Gambino, Salvatore / De Guidi, Giorgio / Barreca, Giovanni / Carnemolla, Francesco / Brighenti, Fabio / Giuffrida, Salvatore /

Pirrotta, Claudia / Carboni, Filippo / Ferranti, Luigi / Valoroso, Luisa / Toscani, Giovanni / Barchi, Massimiliano R / Roberts, Gerald / Brozzetti, Francesco

Scientific data

2024 Volume 11, Issue 1, Page(s) 189

Abstract: QUIN database integrates and organizes structural-geological information from published and unpublished sources to constrain deformation in seismotectonic studies. The initial release, QUIN1.0, comprised 3,339 Fault Striation Pairs, mapped on 445 sites ... ...

Abstract	QUIN database integrates and organizes structural-geological information from published and unpublished sources to constrain deformation in seismotectonic studies. The initial release, QUIN1.0, comprised 3,339 Fault Striation Pairs, mapped on 445 sites exposed along the Quaternary faults of central Italy. The present Data Descriptor introduces the QUIN 2.0 release, which includes 4,297 Fault Striation Pairs on 738 Structural Sites from southern Italy. The newly investigated faults span ~500 km along the Apennines chain, with strikes transitioning from ~SE to ~SW and comprehensively details Fault Striation Pairs' location, attitude, kinematics, and deformation axes. Additionally, it offers a shapefile of the fault traces hosting the data. The QUIN 2.0 release offers a significant geographic extension to the QUIN 1.0, with comprehensive description of local geometric-kinematic complexities of the regional pattern. The QUIN data may be especially relevant for constraining intra-Apennine potential seismogenic deformation patterns, where earthquake data only offer scattered or incomplete information. QUIN's data will support studies aimed at enhancing geological understanding, hazard assessment and comprehension of fault rupture propagation and barriers.
Language	English
Publishing date	2024-02-12
Publishing country	England
Document type	Dataset ; Journal Article
ZDB-ID	2775191-0
ISSN	2052-4463 ; 2052-4463
ISSN (online)	2052-4463
ISSN	2052-4463
DOI	10.1038/s41597-024-03008-6
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Article: Coseismic Stress and Strain Field Changes Investigation Through 3‐D Finite Element Modeling of DInSAR and GPS Measurements and Geological/Seismological Data: The L'Aquila (Italy) 2009 Earthquake Case Study

Castaldo, R. / de Nardis, R. / DeNovellis, V. / Ferrarini, F. / Lanari, R. / Lavecchia, G. / Pepe, S. / Solaro, G. / Tizzani, P.

Journal of geophysical research. 2018 May, v. 123, no. 5

2018

Abstract: We investigate the L'Aquila 2009 earthquake (AQE, Mw 6.3, Italy) through a 3‐D Finite Element (FE) mechanical model based on the exploitation of ENVISAT DInSAR and GPS measurements and an independently generated fault model. The proposed approach mainly ... ...

Abstract	We investigate the L'Aquila 2009 earthquake (AQE, Mw 6.3, Italy) through a 3‐D Finite Element (FE) mechanical model based on the exploitation of ENVISAT DInSAR and GPS measurements and an independently generated fault model. The proposed approach mainly consists of (a) the generation of a 3‐D fault model of the active structures involved in the sequence and those neighboring to them, benefiting of a large geological and seismological data set; (b) the implementation of the generated 3‐D fault model in a FE environment, by exploiting the elastic dislocation theory and considering the curved fault geometry and the crustal heterogeneities information; and (c) the optimization of the seismogenic crustal blocks model parameters in order to reproduce the geodetic measurements. We show that our modeling approach allows us to well reproduce the coseismic surface displacements, including their significant asymmetric pattern, as shown by the very good fit between the modeled ground deformations and the geodetic measurements. Moreover, a comparative analysis between our FE model results and those obtained by considering a classical analytical (Okada) model, for both the surface displacements and the Coulomb stress changes, has been performed. Our model permits to investigate the coseismic stress and strain field changes relevant to the investigated volume and their relationships with the surrounding geological structures; moreover, it highlights the very good correlation with the seismicity spatial distribution. The retrieved stress field changes show different maxima: (a) at few kilometers depth, within the main event surface rupture zone; (b) at depths of 5–9 km in correspondence of main event hypocentral area, along the SW dipping Paganica Fault System (PFS); and (c) at depths of 12–14 km, in correspondence of the largest aftershock hypocentral area, along a steep segment of an underlying east dipping basal detachment. Moreover, the main event hypocenter is localized in a region of high‐gradient strain field changes, while a deeper volumetric dilatation lobe involves the largest aftershock zone. From these findings, we argue that the AQE hanging wall downward movement along the steep portion of PFS might have been modulated by the underlying basal detachment; on the other hand, the coseismic eastward motion of the PFS footwall might have triggered further slip on the OS, thus releasing the largest aftershock on an independent source. The retrieved stress and strain field changes, which support the active role of the OS, have been also validated through a comparative analysis with those obtained from independent geological, seismological, and GPS measurements.
Keywords	case studies ; data collection ; earthquakes ; finite element analysis ; geodesy ; geometry ; geophysics ; mechanical models ; research ; Italy
Language	English
Dates of publication	2018-05
Size	p. 4193-4222.
Publishing place	John Wiley & Sons, Ltd
Document type	Article
Note	JOURNAL ARTICLE
ISSN	2169-9313
DOI	10.1002/2017JB014453
Database	NAL-Catalogue (AGRICOLA)

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Article: QUIZ HQ 39. An uncommon cause of small bowel obstruction.

Greco, S / Patriarca, C / Lavecchia, G / Giunta, P / Gianelli, U / Benetti, G

Journal of gastrointestinal and liver diseases : JGLD

2007 Volume 16, Issue 3, Page(s) 305, 332

MeSH term(s)	Female ; Follow-Up Studies ; Humans ; Ileal Neoplasms/complications ; Ileal Neoplasms/diagnostic imaging ; Ileal Neoplasms/pathology ; Ileal Neoplasms/surgery ; Ileum/pathology ; Immunohistochemistry ; Intestinal Obstruction/diagnosis ; Intestinal Obstruction/etiology ; Laparotomy ; Middle Aged ; Plasmacytoma/complications ; Plasmacytoma/diagnostic imaging ; Plasmacytoma/pathology ; Plasmacytoma/surgery ; Time Factors ; Ultrasonography
Language	English
Publishing date	2007-09
Publishing country	Romania
Document type	Case Reports ; Journal Article
ZDB-ID	2427021-0
ISSN	1841-8724
ISSN	1841-8724
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Article: Ex vivo evaluation of pidotimod activity in patients with chronic obstructive pulmonary disease.

Benetti, G P / Illeni, M T / Passera, A / Bombelli, G / Lavecchia, G / Uslenghi, C

Arzneimittel-Forschung

1994 Volume 44, Issue 12A, Page(s) 1503–1505

Abstract: The aim of this study was to evaluate the activity of pidotimod ((R)-3-[(S)-(5-oxo-2-pyrrolidinyl)carbonyl]-thiazolidine-4-carboxylic acid, PGT/1A, CAS 121808-62-6) on 52 patients affected with chronic obstructive pulmonary disease (COPD). The study was ... ...

Abstract	The aim of this study was to evaluate the activity of pidotimod ((R)-3-[(S)-(5-oxo-2-pyrrolidinyl)carbonyl]-thiazolidine-4-carboxylic acid, PGT/1A, CAS 121808-62-6) on 52 patients affected with chronic obstructive pulmonary disease (COPD). The study was carried out in a randomized, parallel, double-blind trial, followed by incomplete blocks design. Pidotimod 800 mg was administered orally twice a day for 30 days. The follow-up period was 5 weeks. Our results show that in patients with COPD pidotimod potentiates T-cell activity. The effects on T-cells appear after 15 days of treatment and last for 5 weeks after the end of therapy. Since other studies demonstrated that pidotimod displays an immunopotentiating activity also on macrophages and granulocytes, the drug is useful to increase the immune defense during infections. The drug has a good compliance and is well tolerated also during long-term treatment.
MeSH term(s)	Adjuvants, Immunologic/adverse effects ; Adjuvants, Immunologic/therapeutic use ; Adult ; Aged ; Aged, 80 and over ; Double-Blind Method ; Female ; Follow-Up Studies ; Granulocytes/drug effects ; Granulocytes/immunology ; Humans ; Lung Diseases, Obstructive/drug therapy ; Lung Diseases, Obstructive/immunology ; Lymphocyte Activation/drug effects ; Lymphocytes/drug effects ; Lymphocytes/immunology ; Macrophages/drug effects ; Macrophages/immunology ; Male ; Middle Aged ; Pyrrolidonecarboxylic Acid/adverse effects ; Pyrrolidonecarboxylic Acid/analogs & derivatives ; Pyrrolidonecarboxylic Acid/therapeutic use ; Thiazoles/adverse effects ; Thiazoles/therapeutic use ; Thiazolidines
Chemical Substances	Adjuvants, Immunologic ; Thiazoles ; Thiazolidines ; pidotimod (785363R681) ; Pyrrolidonecarboxylic Acid (SZB83O1W42)
Language	English
Publishing date	1994-12
Publishing country	Germany
Document type	Clinical Trial ; Journal Article ; Randomized Controlled Trial
ZDB-ID	502081-5
ISSN	1616-7066 ; 0004-4172
ISSN (online)	1616-7066
ISSN	0004-4172
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Article: Effects of propranolol in a case of orthostatic hypotension.

Brevetti, G / Chiariello, M / Lavecchia, G / Rengo, F

British heart journal

1979 Volume 41, Issue 2, Page(s) 245–248

Abstract: In a hypertensive patient with orthostatic hypotension, the changes in several haemodynamic indices with respect to posture were evaluated. In the upright position, systemic blood pressure was reduced as compared with the supine position, and peripheral ... ...

Abstract	In a hypertensive patient with orthostatic hypotension, the changes in several haemodynamic indices with respect to posture were evaluated. In the upright position, systemic blood pressure was reduced as compared with the supine position, and peripheral vasodilation was present, as shown by an increase in Jantsch's index of the impedance plethysmographic tracings. Systolic time intervals remained unchanged with changes in posture. Propranolol 10 mg intravenously brought the response to normal. In fact, after beta-blockade in the standing position the blood pressure remained unchanged and normal peripheral vasoconstriction was observed. Similar results were seen during atrial pacing at a constant heart rate of 130 beats/minute. In this patient, propranolol appears to normalise the response to the posture change, by restoring normal vasoconstriction in the upright position.
MeSH term(s)	Blood Pressure/drug effects ; Cardiac Output/drug effects ; Cardiac Pacing, Artificial ; Humans ; Hypotension, Orthostatic/drug therapy ; Male ; Middle Aged ; Propranolol/pharmacology ; Propranolol/therapeutic use ; Vasodilation/drug effects
Chemical Substances	Propranolol (9Y8NXQ24VQ)
Language	English
Publishing date	1979-02
Publishing country	England
Document type	Case Reports ; Journal Article
ZDB-ID	80073-9
ISSN	0007-0769
ISSN	0007-0769
DOI	10.1136/hrt.41.2.245
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