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  1. Article ; Online: Reply to letter regarding 'Descemet's membrane or confirmation of a novel corneal structure: the layer of Dua'.

    Athanasiadis, Yannis / Tsatsos, Michael / Ntonti, Panagiota / Panagiotopoulou, Eirini-Kanella / Labiris, Georgios

    Eye (London, England)

    2024  

    Language English
    Publishing date 2024-05-13
    Publishing country England
    Document type Letter
    ZDB-ID 91001-6
    ISSN 1476-5454 ; 0950-222X
    ISSN (online) 1476-5454
    ISSN 0950-222X
    DOI 10.1038/s41433-024-03121-1
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  2. Article: Bilateral Stellate Nonhereditary Idiopathic Foveomacular Retinoschisis (SNIFR) Incidentally Identified in a Non-Myopic Female.

    Perente, Asli / Dardabounis, Doukas / Perente, Irfan / Konstantinidis, Aristeidis / Labiris, Georgios

    Cureus

    2023  Volume 15, Issue 8, Page(s) e42805

    Abstract: Stellate foveomacular retinoschisis is commonly associated with congenital X-linked retinoschisis, which is almost exclusively seen bilaterally in males. In the absence of a family history of retinoschisis and other related conditions, the term stellate ... ...

    Abstract Stellate foveomacular retinoschisis is commonly associated with congenital X-linked retinoschisis, which is almost exclusively seen bilaterally in males. In the absence of a family history of retinoschisis and other related conditions, the term stellate nonhereditary idiopathic foveomacular retinoschisis (SNIFR) is used. SNIFR constitutes a rather rare diagnosis and is usually observed unilaterally in myopic females. Within this context, we report a case of a non-myopic female patient with bilateral SNIFR detected with optical coherence tomography (OCT).
    Language English
    Publishing date 2023-08-01
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.42805
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  3. Article: Impact of Light Conditions on Visual Performance following Premium Pseudophakic Presbyopia Corrections.

    Panagiotopoulou, Eirini-Kanella / Boboridis, Kostas / Seimenis, Ioannis / Labiris, Georgios

    Journal of clinical medicine

    2023  Volume 12, Issue 13

    Abstract: The primary objective of this study was to objectively compare the visual performance of patients following premium pseudophakic presbyopia corrections in different light combinations for near- and intermediate-vision activities of daily living (ADLs). ... ...

    Abstract The primary objective of this study was to objectively compare the visual performance of patients following premium pseudophakic presbyopia corrections in different light combinations for near- and intermediate-vision activities of daily living (ADLs). This is a prospective, comparative study. A total of 75 patients populated three study groups: G1-patients with bilateral trifocal implantation, G2-patients with bilateral bifocal implantation, and G3-patients with bilateral monofocal implantation. All participants addressed 10 ADLs in nine combinations of light temperature (3000 K, 4000 K, and 6000 K) and light intensity (25 fc, 50 fc, and 75 fc) and declared their subjectively optimal light combination while reading. G2 and G3 had the best total ADL scores in 6000 K/75 fc, while G1 had the best total ADL score in 4000 K/75 fc. Total ADL, easy ADL, and moderate difficulty ADL scores were significantly better in G2, while difficult ADL score was significantly better in G1. The majority of all groups selected 6000 K/75 fc as the most comfortable light combination, and no group selected 3000 K and 25 fc. In conclusion, trifocal patients benefit from intense daylight, while bifocal and monofocal patients benefit from intense, cold lighting. Trifocal patients present superior near-vision capacity in difficult near-vision daily tasks, while bifocal patients present superiority in easy and moderate-difficulty ADLs.
    Language English
    Publishing date 2023-06-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12134324
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  4. Article ; Online: Mix-and-match vs bilateral trifocal and bilateral EDOF intraocular lens implantation: the spline curve battle.

    Labiris, Georgios / Panagis, Christos / Ntonti, Panagiota / Konstantinidis, Aristeidis / Bakirtzis, Minas

    Journal of cataract and refractive surgery

    2023  Volume 50, Issue 2, Page(s) 167–173

    Abstract: Purpose: To compare the postoperative visual acuity curves following 3 pseudophakic presbyopic correction techniques.: Setting: Department of Ophthalmology, University Hospital of Alexandroupolis, Alexandroupolis, Greece.: Design: Prospective, ... ...

    Abstract Purpose: To compare the postoperative visual acuity curves following 3 pseudophakic presbyopic correction techniques.
    Setting: Department of Ophthalmology, University Hospital of Alexandroupolis, Alexandroupolis, Greece.
    Design: Prospective, randomized, comparative trial.
    Methods: For this study, patients with stage 2 Lens Opacities Classification System III cataract were divided into 3 study groups: (1) premium monovision group, including patients who received the Panoptix intraocular lens (IOL) in the recessive eye and Vivity IOL in the dominant one; (2) bilateral trifocal group, including those who received bilaterally the Panoptix IOL; and (3) bilateral xEDOF group, including patients who received bilaterally the Vivity IOL. Postoperative bilateral uncorrected distance visual acuity was measured at 25.5, 28, 33, 40, 50, 66, 100, 200, and 300 cm distances. Spline curve fitting was attempted, and areas of the curves (AOCs) and curvature k were calculated. All patients responded to the National Eye Institute Visual Functioning Questionnaire-25 (NEI-VFQ-25).
    Results: 90 patients were equally divided into the 3 groups. Premium monovision and bilateral trifocal implantations delivered similar visual acuity (all AOC P > .05); however, the trifocal patients suffered from drops in vision acuity in certain distance ranges as expressed by negative curvature values. Bilateral xEDOF patients demonstrated worse near vision acuity ( P < .05). Premium monovision patients reported better scores in NEI-VFQ 25 ( P = .03) and in the near activities ( P = .02) and distant activities ( P = .04) subscales.
    Conclusions: All surgical options provided impressive outcomes. Premium monovision appeared to deliver the best results.
    MeSH term(s) Humans ; Lens Implantation, Intraocular/methods ; Refraction, Ocular ; Pseudophakia/surgery ; Prospective Studies ; Prosthesis Design ; Lenses, Intraocular ; Cataract/complications ; Patient Satisfaction ; Phacoemulsification
    Language English
    Publishing date 2023-10-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632744-8
    ISSN 1873-4502 ; 0886-3350
    ISSN (online) 1873-4502
    ISSN 0886-3350
    DOI 10.1097/j.jcrs.0000000000001336
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  5. Article ; Online: Sodium-Hyaluronate Cystic-like Lesion in the Anterior Chamber Following Cataract Surgery: A Case Report.

    Mitsi, Christina / Bakirtzis, Minas / Panagiotopoulou, Eirini-Kanella / Labiris, Georgios

    Acta medica (Hradec Kralove)

    2023  Volume 66, Issue 2, Page(s) 72–74

    Abstract: This is a case report describing the uncommon finding of a cystic-like lesion and its management in the anterior chamber of a male patient after cataract surgery. ...

    Abstract This is a case report describing the uncommon finding of a cystic-like lesion and its management in the anterior chamber of a male patient after cataract surgery.
    MeSH term(s) Male ; Humans ; Hyaluronic Acid ; Cataract Extraction/adverse effects ; Anterior Chamber ; Cataract/etiology ; Sodium
    Chemical Substances Hyaluronic Acid (9004-61-9) ; Sodium (9NEZ333N27)
    Language English
    Publishing date 2023-11-06
    Publishing country Czech Republic
    Document type Case Reports ; Journal Article
    ZDB-ID 1360995-6
    ISSN 1805-9694 ; 1211-4286
    ISSN (online) 1805-9694
    ISSN 1211-4286
    DOI 10.14712/18059694.2023.19
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  6. Article: Development and Validation of a Lighting Facility for the Objective Assessment of the Visual Performance of Presbyopic Patients in a Series of Activities of Daily Living.

    Labiris, Georgios / Panagiotopoulou, Eirini-Kanella / Ntonti, Panagiota

    Cureus

    2022  Volume 14, Issue 4, Page(s) e24548

    Abstract: Introduction The primary objective of this study is to develop and validate an experimental lighting facility that allows the evaluation of near and intermediate vision in different user-defined illuminance levels. Methods This is a prospective, ... ...

    Abstract Introduction The primary objective of this study is to develop and validate an experimental lighting facility that allows the evaluation of near and intermediate vision in different user-defined illuminance levels. Methods This is a prospective, randomized, controlled study. Normophakic patients populated three validation groups (VGs) according to their binocular uncorrected near visual acuity (UNVA): a) VG1, 0.0-0.1 logMAR; b) VG2, 0.4 logMAR; and c) VG3, 0.7 logMAR. All participants addressed 10 near and intermediate activities of daily life (ADLs) in the three following lighting settings: 1) 25 foot candles (fc)/3000 kelvins (K), 2) 50 fc/4000 K, and 3) 75 fc/6000 K. Results Thirty patients in each group performed all ADLs in the three lighting settings. VG1 demonstrated the best ADL scores in all ADLs and lighting settings, followed by the VG2. VG3 presented the worst scores. ADLs using printed material showed significant differences among the three lighting settings for all study groups, while ADLs using screens or needing manual dexterity demonstrated no significant differences except for the Screwdriver Test (ST) in VG1. All ADL scores demonstrated a high correlation with UNVA in all lighting settings (p < 0.001). Conclusion This is the first study that validates a lighting facility for comparative studies in patients with different near vision capacities performing a series of ADLs.
    Language English
    Publishing date 2022-04-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.24548
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  7. Article: Evaluation of the red reflex: An overview for the pediatrician.

    Toli, Aspasia / Perente, Asli / Labiris, Georgios

    World journal of methodology

    2021  Volume 11, Issue 5, Page(s) 263–277

    Abstract: Background: Red reflex test (RRT) is a simple, non-invasive method that can be performed easily by pediatricians during the clinical examination in neonatal period, infancy and childhood. Abnormal reflexes can lead to prompt diagnosis of several ocular ... ...

    Abstract Background: Red reflex test (RRT) is a simple, non-invasive method that can be performed easily by pediatricians during the clinical examination in neonatal period, infancy and childhood. Abnormal reflexes can lead to prompt diagnosis of several ocular disorders, with potentially severe consequences on patient's vision, cognitive function and even life.
    Aim: To underline the contribution of pediatricians to early detection of vision and life threatening diseases by using RRT effectively.
    Methods: For the present systematic review, PubMed searches were performed using the key words "red reflex and newborn"; "red reflex and neonate"; "red reflex and complications"; "red reflex and necessity"; "red reflex and retinoblastoma"; "red reflex and congenital cataract"; "red reflex and glaucoma"; "red reflex and prematurity"; "red reflex and leukocoria"; "red reflex and blindness"; "red reflex sensitivity and specificity"; "red reflex and differential diagnosis"; "red reflex and guidelines". The relevant articles were selected without language restrictions. When a full-text publication was not available, their English abstracts were used. In some cases, studies from the reference lists of the selected articles provided useful information. The research took place in September 2020, in the Ophthalmology Department of University Hospital of Alexandroupolis.
    Results: A total of 45 articles were selected according to the used key words. After reviewing data from these articles, it is supported that red reflex remains an effective tool of undeniable importance for early detection of severe eye conditions, such as cataract, retinoblastoma, retinopathy of prematurity and glaucoma. Although literature reports some limitations of RRT, including a notable percentage of false positive tests, the inability to detect small, peripheral retinoblastomas and the lower sensitivity for posterior segment pathology, it is widely accepted that the benefits from the regular evaluation of the test on public health are significant. Therefore, RRT has been established by international guidelines and should be an essential component of pediatricians clinical practice. Red reflex implementation should be incorporated in pediatricians educational programs, so that they would be able to provide quality services and safe diagnoses.
    Conclusion: The implementation of RRT should be encouraged in all neonatal/pediatric departments. Prompt education of pediatricians should be empowered in order to achieve careful vision screening, according to current guidelines.
    Language English
    Publishing date 2021-09-20
    Publishing country United States
    Document type Journal Article
    ISSN 2222-0682
    ISSN 2222-0682
    DOI 10.5662/wjm.v11.i5.263
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  8. Article ; Online: Descemet's membrane or confirmation of a novel corneal structure: the layer of Dua.

    Athanasiadis, Yannis / Tsatsos, Michael / Ntonti, Panagiota / Panagiotopoulou, Eirini-Kanella / Labiris, Georgios

    Eye (London, England)

    2023  Volume 38, Issue 6, Page(s) 1217–1218

    MeSH term(s) Humans ; Descemet Membrane/diagnostic imaging ; Cornea ; Endothelium, Corneal
    Language English
    Publishing date 2023-11-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 91001-6
    ISSN 1476-5454 ; 0950-222X
    ISSN (online) 1476-5454
    ISSN 0950-222X
    DOI 10.1038/s41433-023-02851-y
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  9. Article ; Online: Video-Based Eye Blink Identification and Classification.

    Nousias, George / Panagiotopoulou, Eirini-Kanella / Delibasis, Konstantinos / Chaliasou, Aikaterini-Maria / Tzounakou, Anastasia-Maria / Labiris, Georgios

    IEEE journal of biomedical and health informatics

    2022  Volume 26, Issue 7, Page(s) 3284–3293

    Abstract: Blink detection and classification can provide a very useful clinical indicator, because of its relation with many neurological and ophthalmological conditions. In this work, we propose a system that automatically detects and classifies blinks as " ... ...

    Abstract Blink detection and classification can provide a very useful clinical indicator, because of its relation with many neurological and ophthalmological conditions. In this work, we propose a system that automatically detects and classifies blinks as "complete" or "incomplete" in high resolution image sequences zoomed into the participants' face, acquired during clinical examination using near-Infrared illumination. This method utilizes state-of-the-art (DeepLabv3+) deep learning encoder-decoder neural architecture -DLED to segment iris and eyelid in both eyes in the acquired images. The sequence of the segmented frames is post-processed to calculate the distance between the eyelids of each eye (palpebral fissure height) and the corresponding iris diameter. These quantities are temporally filtered and their fraction is subject to adaptive thresholding to identify blinks and determine their type, independently for each eye. The proposed system was tested on 15 participants, each with one video of 4 to 10 minutes. Several metrics of blink detection and classification accuracy were calculated against the ground truth, which was generated by three (3) independent experts, whose conflicts were resolved by a senior expert. Results show that the proposed system achieved F1-score 95.3% and 80.9% for the classification of complete and incomplete blinks respectively, collectively for all 15 participants, outperforming all 3 experts. The proposed system was proven robust in handling unexpected participant movements and actions, as well as glare and reflections from the spectacles, or face obstruction by facemasks.
    MeSH term(s) Blinking ; Eyelids ; Humans ; Infrared Rays
    Language English
    Publishing date 2022-07-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2695320-1
    ISSN 2168-2208 ; 2168-2194
    ISSN (online) 2168-2208
    ISSN 2168-2194
    DOI 10.1109/JBHI.2022.3153407
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  10. Article: A case of bilateral uveitis in a patient treated with vemurafenib.

    Mehmet, Aysel / Mikropoulou, Athanasia Maria / Panagiotopoulou, Eirini-Kanella / Konstantinidis, Aristeidis / Labiris, Georgios

    Oman journal of ophthalmology

    2022  Volume 15, Issue 3, Page(s) 431–432

    Language English
    Publishing date 2022-11-02
    Publishing country India
    Document type Journal Article
    ZDB-ID 2484272-2
    ISSN 0974-7842 ; 0974-620X
    ISSN (online) 0974-7842
    ISSN 0974-620X
    DOI 10.4103/ojo.ojo_240_21
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