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Article ; Online: The effect of splash block on the need for analgesia in dogs subjected to video-assisted ovariectomy.

Cicirelli, Vincenzo / Lacalandra, Giovanni M / Aiudi, Giulio G

2021 Volume 8, Issue 1, Page(s) 104–109

Abstract: Objectives: The present study aimed to demonstrate the efficacy of splash block using lidocaine to provide additional analgesia during ovariectomy in bitches. To identify an acute intraoperative nociceptive response, three clinical parameters were used: ...

Abstract	Objectives: The present study aimed to demonstrate the efficacy of splash block using lidocaine to provide additional analgesia during ovariectomy in bitches. To identify an acute intraoperative nociceptive response, three clinical parameters were used: increased blood pressure, heart rate and respiratory rate. Material and methods: Forty healthy bitches were randomly assigned to receive 2% lidocaine (L group) topical application (splash block) on both ovaries (2 mg/kg each), or an equal volume of NaCl 0.9% at the same sites (C group). A fentanyl bolus (2 µg/kg) was administered intraoperatively in response to an increase in blood pressure, heart rate or respiratory rate during surgery (> 30% compared with the pre-incisional values). Results: Local lidocaine administration significantly reduced the need for supplementary fentanyl. Dogs in the L group showed greater intraoperative hemodynamic stability and lower surgical pain than those in the C group. In addition to the routine anaesthetic protocol, the local anaesthesia used in the present study was safe and caused no cardiopulmonary suppression. In addition, it significantly reduced the need for mandatory systemic or rescue analgesia. Clinical significance: Ovariectomy is a common surgical procedure in bitches. Analgesia during this procedure is important because intraoperative pain can cause negative effects that prevent patient recovery. This study aimed to demonstrate the analgesic efficacy of lidocaine splash block in video-assisted ovariectomy in dogs. The results showed that splash block improved surgical analgesia during canine laparoscopic ovariectomy. Considering its relative simplicity, low cost, and safety, splash block could be used in daily clinical practice.
MeSH term(s)	Analgesia/methods ; Analgesia/veterinary ; Anesthetics, Local ; Animals ; Dogs ; Female ; Lidocaine ; Ovariectomy/veterinary ; Pain/veterinary
Chemical Substances	Anesthetics, Local ; Lidocaine (98PI200987)
Language	English
Publishing date	2021-10-14
Publishing country	England
Document type	Journal Article ; Randomized Controlled Trial, Veterinary
ZDB-ID	2819409-3
ISSN	2053-1095 ; 2053-1095
ISSN (online)	2053-1095
ISSN	2053-1095
DOI	10.1002/vms3.637
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Local and Regional Anaesthetic Techniques in Canine Ovariectomy: A Review of the Literature and Technique Description.

Cicirelli, Vincenzo / Burgio, Matteo / Lacalandra, Giovanni M / Aiudi, Giulio G

Animals : an open access journal from MDPI

2022 Volume 12, Issue 15

Abstract: Canine ovariectomy is an elective surgery with a moderate level of pain. Despite its relative simplicity, it requires surgical pain management. This study aimed to collect all recent information about local and regional anaesthetic/analgesic techniques ... ...

Abstract	Canine ovariectomy is an elective surgery with a moderate level of pain. Despite its relative simplicity, it requires surgical pain management. This study aimed to collect all recent information about local and regional anaesthetic/analgesic techniques in a review of the literature describing the technique utilised. The various procedures described in this review use local anaesthetics to improve analgesia in the routine systemic anaesthetic protocol. The approach described in this paper is called multimodal analgesia and is used in addition to the normal standard anaesthetic protocol. These techniques proved effective in minimising responses to the surgical stimulus and ensured adequate intraoperative and postoperative analgesia. The routine use of multimodal analgesia is considered a useful alternative for pain management in canine ovariectomy, in that it minimises patient suffering, improves the recovery of rescue analgesia, increases drug savings, and improves animal outcomes. In addition, the use of these local and regional techniques ensures satisfactory analgesic coverage that lasts for the first hours postoperatively.
Language	English
Publishing date	2022-07-27
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2606558-7
ISSN	2076-2615
ISSN	2076-2615
DOI	10.3390/ani12151920
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Article: Local and Regional Anaesthetic Techniques in Canine Ovariectomy: A Review of the Literature and Technique Description

Cicirelli, Vincenzo / Burgio, Matteo / Lacalandra, Giovanni M. / Aiudi, Giulio G.

Animals. 2022 July 27, v. 12, no. 15

2022

Abstract	Canine ovariectomy is an elective surgery with a moderate level of pain. Despite its relative simplicity, it requires surgical pain management. This study aimed to collect all recent information about local and regional anaesthetic/analgesic techniques in a review of the literature describing the technique utilised. The various procedures described in this review use local anaesthetics to improve analgesia in the routine systemic anaesthetic protocol. The approach described in this paper is called multimodal analgesia and is used in addition to the normal standard anaesthetic protocol. These techniques proved effective in minimising responses to the surgical stimulus and ensured adequate intraoperative and postoperative analgesia. The routine use of multimodal analgesia is considered a useful alternative for pain management in canine ovariectomy, in that it minimises patient suffering, improves the recovery of rescue analgesia, increases drug savings, and improves animal outcomes. In addition, the use of these local and regional techniques ensures satisfactory analgesic coverage that lasts for the first hours postoperatively.
Keywords	analgesia ; analgesics ; dogs ; ovariectomy ; pain ; patients ; protocols
Language	English
Dates of publication	2022-0727
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
ZDB-ID	2606558-7
ISSN	2076-2615
ISSN	2076-2615
DOI	10.3390/ani12151920
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Fentanyl patch versus tramadol for the control of postoperative pain in canine ovariectomy and mastectomy.

Cicirelli, Vincenzo / Aiudi, Giulio G / Mrenoshki, Daniela / Lacalandra, Giovanni M

Veterinary medicine and science

2021 Volume 8, Issue 2, Page(s) 469–475

Abstract: Objectives: The purpose of the present study was to evaluate the postoperative analgesic efficacy of fentanyl patches versus subcutaneous tramadol after canine ovariectomy, with and without unilateral mastectomy.: Materials and methods: A total of 40 ...

Abstract	Objectives: The purpose of the present study was to evaluate the postoperative analgesic efficacy of fentanyl patches versus subcutaneous tramadol after canine ovariectomy, with and without unilateral mastectomy. Materials and methods: A total of 40 female dogs were included in the present study, all of which were domesticated, healthy and 4-12 years of age. The animals were divided into four groups (n = 10 per group) based on the surgery and the analgesic protocol used: the TO group only underwent ovariectomy, and received postoperative tramadol; the TM group underwent both ovariectomy and mastectomy, and received postoperative tramadol; the FO group only underwent ovariectomy, and received fentanyl patches; and the FM group underwent both ovariectomy and mastectomy, and received fentanyl patches. Postoperative pain was evaluated every 4 h for 24 h using a numeric analogue scale (NAS) and a modified Glasgow Composite Measure Pain Scale Short Form (CMPS-SF). Results: The results of the present study showed that patients in all four groups tolerated postoperative surgical stress well. Analysis of variance for repeated measures did not show significant differences in the NAS scores and in Glasgow CMPS-SF between groups in terms of pain scores or rescue analgesia. Clinical significance: These results indicated that the analgesic effect of the fentanyl patch was similar to that of subcutaneous (SC) tramadol in female dogs after ovariectomy, with and without unilateral mastectomy, suggesting that the fentanyl patch may represent a valid supplementary tool for the control of postoperative pain in animals after surgery.
MeSH term(s)	Analgesics ; Analgesics, Opioid/therapeutic use ; Animals ; Dog Diseases/drug therapy ; Dog Diseases/surgery ; Dogs ; Female ; Fentanyl/therapeutic use ; Male ; Mastectomy/adverse effects ; Mastectomy/methods ; Mastectomy/veterinary ; Ovariectomy/adverse effects ; Ovariectomy/veterinary ; Pain, Postoperative/drug therapy ; Pain, Postoperative/prevention & control ; Pain, Postoperative/veterinary ; Tramadol/therapeutic use
Chemical Substances	Analgesics ; Analgesics, Opioid ; Tramadol (39J1LGJ30J) ; Fentanyl (UF599785JZ)
Language	English
Publishing date	2021-12-24
Publishing country	England
Document type	Journal Article
ZDB-ID	2819409-3
ISSN	2053-1095 ; 2053-1095
ISSN (online)	2053-1095
ISSN	2053-1095
DOI	10.1002/vms3.691
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Tissue sealing versus suture ligation in open canine ovariectomy: Surgical times, intraoperative nociceptive response and frequency of complications.

Cicirelli, Vincenzo / Burgio, Matteo / Carbonari, Alice / Lacalandra, Giovanni M / Aiudi, Giulio G

Veterinary medicine and science

2022 Volume 9, Issue 1, Page(s) 76–81

Abstract: Background: In this study, we compared two different techniques currently used for open canine ovariectomy: traditional method utilising absorbable suture and vessel sealing device (ENSEAL: Objectives: The aim of this study was to compare the ... ...

Abstract	Background: In this study, we compared two different techniques currently used for open canine ovariectomy: traditional method utilising absorbable suture and vessel sealing device (ENSEAL Objectives: The aim of this study was to compare the surgical times, intraoperative nociceptive response and the frequency of intraoperative complications in the canine ovariectomy procedure using these two techniques. Methods: Forty bitches were randomly divided into two groups. The Control Group (C) will use a classic open surgery approach using ligatures with absorbable suture and ovarian resection with a scalpel blade. In the Group E, resection of ovarian structures was performed with ENSEAL Results: The results of this study showed that the procedures performed using ENSEAL Conclusions: The present study shows that the use of ENSEAL
MeSH term(s)	Female ; Dogs ; Animals ; Operative Time ; Nociception ; Ovariectomy/veterinary ; Intraoperative Complications/veterinary ; Sutures/veterinary ; Dog Diseases
Language	English
Publishing date	2022-12-14
Publishing country	England
Document type	Randomized Controlled Trial, Veterinary ; Journal Article
ZDB-ID	2819409-3
ISSN	2053-1095 ; 2053-1095
ISSN (online)	2053-1095
ISSN	2053-1095
DOI	10.1002/vms3.1012
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Article: Ultrasound-Guided Funicular Block: Ropivacaine Injection into the Tissue around the Spermatic Cord to Improve Analgesia during Orchiectomy in Dogs

Cicirelli, Vincenzo / Debidda, Pasquale / Maggio, Nicola / Caira, Michele / Lacalandra, Giovanni M / Aiudi, Giulio G

Animals. 2021 Apr. 28, v. 11, no. 5

2021

Abstract: Orchiectomy is a common surgical procedure performed on small animals, and it requires postoperative pain management despite its relative simplicity. This study aimed to evaluate the hemodynamic stability, intraoperative administration of additional ... ...

Abstract	Orchiectomy is a common surgical procedure performed on small animals, and it requires postoperative pain management despite its relative simplicity. This study aimed to evaluate the hemodynamic stability, intraoperative administration of additional hypnotic and/or analgesic drugs, and postoperative pain scores following the combination of ultrasound-guided injection of ropivacaine hydrochloride into the spermatic cord and infiltration by the same anaesthetic of the incisional prescrotal line (ROP) or general anaesthesia. Dogs in the ROP group showed greater intraoperative hemodynamic stability and lower pain scores than the control group. The locoregional approach used in this study proved effective in minimising the responses to the surgical stimulus and ensured adequate analgesia intra- and postoperatively. This method, called ultrasound-guided funicular block, allows orchiectomy to be performed under deep sedation without general anaesthesia.
Keywords	analgesia ; analgesics ; anesthesia ; castration ; hemodynamics ; pain ; sedation ; spermatic cord ; ultrasonography
Language	English
Dates of publication	2021-0428
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
Note	NAL-AP-2-clean
ISSN	2076-2615
DOI	10.3390/ani11051275
Database	NAL-Catalogue (AGRICOLA)

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Article: Ultrasound-Guided Funicular Block: Ropivacaine Injection into the Tissue around the Spermatic Cord to Improve Analgesia during Orchiectomy in Dogs.

Cicirelli, Vincenzo / Debidda, Pasquale / Maggio, Nicola / Caira, Michele / Lacalandra, Giovanni M / Aiudi, Giulio G

Animals : an open access journal from MDPI

2021 Volume 11, Issue 5

Abstract	Orchiectomy is a common surgical procedure performed on small animals, and it requires postoperative pain management despite its relative simplicity. This study aimed to evaluate the hemodynamic stability, intraoperative administration of additional hypnotic and/or analgesic drugs, and postoperative pain scores following the combination of ultrasound-guided injection of ropivacaine hydrochloride into the spermatic cord and infiltration by the same anaesthetic of the incisional prescrotal line (ROP) or general anaesthesia. Dogs in the ROP group showed greater intraoperative hemodynamic stability and lower pain scores than the control group. The locoregional approach used in this study proved effective in minimising the responses to the surgical stimulus and ensured adequate analgesia intra- and postoperatively. This method, called ultrasound-guided funicular block, allows orchiectomy to be performed under deep sedation without general anaesthesia.
Language	English
Publishing date	2021-04-28
Publishing country	Switzerland
Document type	Journal Article
ISSN	2076-2615
ISSN	2076-2615
DOI	10.3390/ani11051275
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Article: Use of Spinal Anaesthesia with Anaesthetic Block of Intercostal Nerves Compared to a Continuous Infusion of Sufentanyl to Improve Analgesia in Cats Undergoing Unilateral Mastectomy

Cicirelli, Vincenzo / Debidda, Pasquale / Maggio, Nicola / Caira, Michele / Mrenoshki, Daniela / Aiudi, Giulio G / Lacalandra, Giovanni M

Animals. 2021 Mar. 20, v. 11, no. 3

2021

Abstract: Unilateral mastectomy is a common surgical procedure in feline species and requires postoperative pain management. Our study aimed to evaluate the analgesic efficacy of subarachnoid anaesthesia combined with an intercostal nerve block, in comparison with ...

Abstract	Unilateral mastectomy is a common surgical procedure in feline species and requires postoperative pain management. Our study aimed to evaluate the analgesic efficacy of subarachnoid anaesthesia combined with an intercostal nerve block, in comparison with the use of sufentanyl citrate administered as a constant-rate infusion (CRI). Twenty cats were randomly divided into two groups (n = 10/group) based on the analgesic protocol used: the first received loco-regional anaesthesia with levobupivacaine (LR group), and the second received a CRI of sufentanyl (SUF group). The evaluation criteria during surgery were the need for a bolus of fentanyl in the event of an increased heart rate or increased blood pressure. In the postoperative period, the levels of comfort/discomfort and pain were used to obtain a score according to the UNESP-Botucatu multimodal scale. Subjects who scored above seven received analgesic drug supplementation. Intraoperative analgesia was satisfactory, with good haemodynamic stability in both groups. Four patients in the LR group required an extra dose of methadone after they achieved the sternal decubitus position, whereas those in the SUF group required many more doses. The analgesia achieved in the LR group was more satisfactory than that in the SUF group.
Keywords	analgesia ; anesthesia ; blood pressure ; cats ; citrates ; fentanyl ; heart rate ; methadone ; nerve tissue ; pain ; protocols ; surgery
Language	English
Dates of publication	2021-0320
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
Note	NAL-light
ISSN	2076-2615
DOI	10.3390/ani11030887
Database	NAL-Catalogue (AGRICOLA)

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Article: Ejaculation Effect on Canine Prostatic Specific Esterase Serum Concentration.

Alonge, Salvatore / Melandri, Monica / Leoci, Raffaella / Lacalandra, Giovanni M / Caira, Michele / Aiudi, Giulio G

Animals : an open access journal from MDPI

2020 Volume 10, Issue 3

Abstract: Canine prostatic diseases are usually asymptomatic in their onset and often identified in advanced stages. Canine prostatic specific esterase (CPSE) represents an early serum marker for prostatic diseases, also in asymptomatic dogs. The present study ... ...

Abstract	Canine prostatic diseases are usually asymptomatic in their onset and often identified in advanced stages. Canine prostatic specific esterase (CPSE) represents an early serum marker for prostatic diseases, also in asymptomatic dogs. The present study aimed to identify the effects of ejaculation on serum CPSE. Twenty adult intact male dogs were enrolled. Blood samples were collected to measure CPSE concentrations before (T0), immediately after (T1), and 24 h post (T2) ejaculation. Data were compared within and between groups by ANOVA (
Language	English
Publishing date	2020-02-27
Publishing country	Switzerland
Document type	Journal Article
ISSN	2076-2615
ISSN	2076-2615
DOI	10.3390/ani10030381
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Article: The Effect of Dietary Supplementation of Vitamin E, Selenium, Zinc, Folic Acid, and N-3 Polyunsaturated Fatty Acids on Sperm Motility and Membrane Properties in Dogs

Alonge, Salvatore / Melandri, Monica / Leoci, Raffaella / Lacalandra, Giovanni M / Caira, Michele / Aiudi, Giulio G

Animals. 2019 Jan. 24, v. 9, no. 2

2019

Abstract: Sub-fertility represents a common challenge in canine reproduction. Different protocols, supplementing daily given quantities of micronutrients, were investigated to improve poor sperm concentration and/or function, which represent breeding major ... ...

Abstract	Sub-fertility represents a common challenge in canine reproduction. Different protocols, supplementing daily given quantities of micronutrients, were investigated to improve poor sperm concentration and/or function, which represent breeding major constraining factors in the canine species. Little information is available for dogs concerning the effect of a daily supplementation with a complex of vitamin E, zinc, selenium, folic acid, and n-3 polyunsaturated fatty acids (PUFA) on semen quality. Thus, the present study investigated this effect on semen motility and sperm membrane properties. Serial semen analyses from fourteen healthy normospermic dogs, fed with the same commercial diet, were performed on Days 0 (T0), 30 (T30), 60 (T60), and 90 (T90). Seven dogs were randomly included in the treatment (T) group, receiving a supplementation of vitamin E, zinc, selenium, folic acid, n-3 PUFA; and seven other subjects composed the control (C) group. Total Sperm Count (TSC), Computer-Assisted Sperm Analysis (CASA) indexes, mortality, and functional membrane integrity were assessed. The ANOVA compared results between groups and sampling times (p < 0.05). From T60, the supplementation significantly improved TSC, progressive motility, functional membrane integrity, and decreased mortality. Present results lead us to consider ameliorative effects of a two-month healthy diet supplementation on canine spermatozoa. The positive effects of the described balanced integration of micronutrients on sperm motility and prevention of oxidative stress should be considered, especially when decreased seminal parameters may result from inadequate intake, reduced absorption, increased losses or demand, or to attenuate the impact of age.
Keywords	absorption ; analysis of variance ; breeding ; dietary supplements ; dogs ; folic acid ; healthy diet ; mortality ; omega-3 fatty acids ; oxidative stress ; polyunsaturated fatty acids ; selenium ; semen quality ; sperm concentration ; sperm motility ; spermatozoa ; vitamin E ; zinc
Language	English
Dates of publication	2019-0124
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
ISSN	2076-2615
DOI	10.3390/ani9020034
Database	NAL-Catalogue (AGRICOLA)

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