Article ; Online: Associations of Dynapenic Obesity and Sarcopenic Obesity with the Risk of Complications in COVID-19.
International journal of molecular sciences
2022 Volume 23, Issue 15
Abstract: Ageing is associated with changes in body composition, such as low muscle mass (sarcopenia), decreased grip strength or physical function (dynapenia), and accumulation of fat mass. When the accumulation of fat mass synergistically accompanies low muscle ... ...
| Abstract | Ageing is associated with changes in body composition, such as low muscle mass (sarcopenia), decreased grip strength or physical function (dynapenia), and accumulation of fat mass. When the accumulation of fat mass synergistically accompanies low muscle mass or reduced grip strength, it results in sarcopenic obesity and dynapenic obesity, respectively. These types of obesity contribute to the increased risk of cardiovascular disease and mortality in the elderly, which could increase the damage caused by COVID-19. In this review, we associated factors that could generate a higher risk of COVID-19 complications in dynapenic obesity and sarcopenic obesity. For example, skeletal muscle regulates the expression of inflammatory cytokines and supports metabolic stress in pulmonary disease; hence, the presence of dynapenic obesity or sarcopenic obesity could be related to a poor prognosis in COVID-19 patients. |
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| MeSH term(s) | Aged ; Body Composition ; COVID-19/complications ; Hand Strength ; Humans ; Muscle Strength/physiology ; Muscle, Skeletal ; Obesity/complications ; Sarcopenia/etiology |
| Language | English |
| Publishing date | 2022-07-27 |
| Publishing country | Switzerland |
| Document type | Journal Article ; Review |
| ZDB-ID | 2019364-6 |
| ISSN | 1422-0067 ; 1422-0067 ; 1661-6596 |
| ISSN (online) | 1422-0067 |
| ISSN | 1422-0067 ; 1661-6596 |
| DOI | 10.3390/ijms23158277 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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