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Article ; Online: Anti-tumor effect of endostatin in a sleep-apnea mouse model with tumor.

Zhang, X-B / Yang, Y-Y / Zeng, Y / Zeng, H-Q / Fu, B-B / Ko, C-Y / Luo, X / Du, Y-P / Chen, L-D / Lai, Y-T / Wu, Y

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico

2018 Volume 21, Issue 5, Page(s) 572–581

Abstract: Background: Obstructive sleep apnea (OSA) is associated with cancer incidence and mortality. The underlying mechanism is unclear. This study aims to evaluate the influence of intermittent hypoxia (IH), a novel hallmark of OSA, on tumor and to access the ...

Abstract	Background: Obstructive sleep apnea (OSA) is associated with cancer incidence and mortality. The underlying mechanism is unclear. This study aims to evaluate the influence of intermittent hypoxia (IH), a novel hallmark of OSA, on tumor and to access the anti-tumor effect of endostatin on a mouse model with OSA. Methods: The C57BL/6 J mice were randomly classified into four groups: control (normoxia) (CTL), control plus endostatin (CTL + ED), IH, and IH plus endostatin (IH + ED). Mice in IH and IH + ED groups were subjected to IH 8 h per day in 5 weeks. Lewis lung cancer cells were injected into the flank of each mouse after 1 week of IH exposure. Endostatin was also intraperitoneally injected after tumor volume reached about 200 mm Results: Mice had higher SUVmax in the IH group than the CTL group (p < 0.01). When compared with mice in the CTL group, those in the IH group had significantly greater MVD values (p < 0.001). The SUVmax can be attenuated by endostatin both in the CTL (p < 0.01) and IH conditions (p < 0.001). When compared with CTL group, mice in the IH group had increased MVD values (p < 0.001) and VEGF expression both at mRNA (p < 0.05) and protein levels (p < 0.001 in western blotting results). Treatment with endostatin attenuated serum and tissue VEGF levels, lowering the MVD values. As compared to normoxia condition, the endostatin-therapeutic effects were more significant under the IH condition (p < 0.05 in western blotting results). Conclusions: Micro-PET-CT imaging is a promising non-invasive technique to evaluate the tumor metabolic characteristics under IH condition in vivo. The anti-tumor effect of endostatin under IH condition is superior to that of the normoxia condition.
MeSH term(s)	Animals ; Antineoplastic Agents/pharmacology ; Carcinoma, Lewis Lung/drug therapy ; Carcinoma, Lewis Lung/etiology ; Disease Models, Animal ; Endostatins/pharmacology ; Hypoxia/physiopathology ; Male ; Mice ; Mice, Inbred C57BL ; Sleep Apnea, Obstructive/complications ; Tumor Cells, Cultured
Chemical Substances	Antineoplastic Agents ; Endostatins
Language	English
Publishing date	2018-10-06
Publishing country	Italy
Document type	Journal Article
ZDB-ID	2397359-6
ISSN	1699-3055 ; 1699-048X
ISSN (online)	1699-3055
ISSN	1699-048X
DOI	10.1007/s12094-018-1955-8
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Article: Visualization of repair of double-strand breaks in the bacteriophage T7 genome without normal DNA replication.

Lai, Y T / Masker, W

Journal of bacteriology

2000 Volume 182, Issue 2, Page(s) 327–336

Abstract: An in vitro system based on extracts of Escherichia coli infected with bacteriophage T7 is able to repair double-strand breaks in a T7 genome with efficiencies of 20% or more. To achieve this high repair efficiency it is necessary that the reaction ... ...

Abstract	An in vitro system based on extracts of Escherichia coli infected with bacteriophage T7 is able to repair double-strand breaks in a T7 genome with efficiencies of 20% or more. To achieve this high repair efficiency it is necessary that the reaction mixtures contain molecules of donor DNA that bracket the double-strand break. Gaps as long as 1,600 nucleotides are repaired almost as efficiently as simple double-strand breaks. DNA synthesis was measured while repair was taking place. It was found that the amount of DNA synthesis associated with repair of a double-strand break was below the level of detection possible with this system. Furthermore, repair efficiencies were the same with or without normal levels of T7 DNA polymerase. However, the repair required the 5'-->3' exonuclease encoded by T7 gene 6. The high efficiency of DNA repair allowed visualization of the repaired product after in vitro repair, thereby assuring that the repair took place in vitro rather than during an in vivo growth step after packaging.
MeSH term(s)	Bacteriophage T7/genetics ; Base Sequence ; DNA Repair ; DNA Replication ; DNA, Viral/chemistry ; DNA-Directed DNA Polymerase/metabolism ; Deoxyribonucleases, Type II Site-Specific/metabolism ; Genome, Viral ; Molecular Sequence Data
Chemical Substances	DNA, Viral ; bacteriophage T7 induced DNA polymerase (EC 2.7.7.-) ; DNA-Directed DNA Polymerase (EC 2.7.7.7) ; Deoxyribonucleases, Type II Site-Specific (EC 3.1.21.4) ; GGTACC-specific type II deoxyribonucleases (EC 3.1.21.4)
Language	English
Publishing date	2000-01
Publishing country	United States
Document type	Journal Article ; Research Support, U.S. Gov't, P.H.S.
ZDB-ID	2968-3
ISSN	1098-5530 ; 0021-9193
ISSN (online)	1098-5530
ISSN	0021-9193
DOI	10.1128/JB.182.2.327-336.2000
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Article: Repair of double-strand breaks by incorporation of a molecule of homologous DNA.

Lai, Y T / Masker, W

Molecular microbiology

2000 Volume 36, Issue 2, Page(s) 437–446

Abstract: An in vitro system based upon extracts of Escherichia coli infected with bacteriophage T7 was used to monitor repair of double-strand breaks in the T7 genome. The efficiency of double-strand break repair was markedly increased by DNA molecules ('donor' ... ...

Abstract	An in vitro system based upon extracts of Escherichia coli infected with bacteriophage T7 was used to monitor repair of double-strand breaks in the T7 genome. The efficiency of double-strand break repair was markedly increased by DNA molecules ('donor' DNA) consisting of a 2.1 kb DNA fragment, generated by PCR, that had ends extending approximately 1 kb on either side of the break site. Repair proceeded with greater than 10% efficiency even when T7 DNA replication was inhibited. When the donor DNA molecules were labelled with 32P, repaired genomes incorporated label only near the site of the double-strand break. When repair was carried out with unlabelled donor DNA and [32P]-dCTP provided as precursor for DNA synthesis the small amount of incorporated label was distributed randomly throughout the entire T7 genome. Repair was performed using donor DNA that had adjacent BamHI and PstI sites. When the BamHI site was methylated and the PstI site was left unmethylated, the repaired genomes were sensitive to PstI but not to BamHI endonuclease, showing that the methyl groups at the BamHI recognition site had not been replaced by new DNA synthesis during repair of the double-strand break. These observations are most consistent with a model for double-strand break repair in which the break is widened to a small gap, which is subsequently repaired by physical incorporation of a patch of donor DNA into the gap.
MeSH term(s)	Bacteriophage T7/genetics ; Bacteriophage T7/metabolism ; DNA Damage ; DNA Repair/genetics ; DNA, Viral/metabolism ; Escherichia coli/virology ; Genome, Viral ; Polymerase Chain Reaction
Chemical Substances	DNA, Viral
Language	English
Publishing date	2000-04
Publishing country	England
Document type	Journal Article ; Research Support, U.S. Gov't, P.H.S.
ZDB-ID	619315-8
ISSN	1365-2958 ; 0950-382X
ISSN (online)	1365-2958
ISSN	0950-382X
DOI	10.1046/j.1365-2958.2000.01861.x
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Zs.A 2502: Show issues

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Article ; Online: Synthesis and characterization of Pt nanoparticles with different morphologies in mesoporous silica SBA-15 for methanol oxidation reaction.

Chen, C S / Lai, Y T / Chen, T C / Chen, C H / Lee, J F / Hsu, C W / Kao, H M

Nanoscale

2014 Volume 6, Issue 21, Page(s) 12644–12654

Abstract: Mesoporous SBA-15 silica materials functionalized with and without carboxylic acid groups were used to effectively control the morphology of Pt crystals, and the materials thus obtained were applied to methanol oxidation reactions. The Pt particles ... ...

Abstract	Mesoporous SBA-15 silica materials functionalized with and without carboxylic acid groups were used to effectively control the morphology of Pt crystals, and the materials thus obtained were applied to methanol oxidation reactions. The Pt particles aggregated to form long spheroids inside the channels in pure SBA-15. When carboxylic acid groups were utilized, the SBA-15(-COOH) material facilitated the formation of higher Pt surface area, smaller Pt nanoparticles and nearly spherical shape due to the strong interaction between Pt(4+) ions and carboxylic acid on SBA-15. The Pt(4+) ions on the SBA-15(-COOH) material can be directly transformed to reduced Pt particles during calcination. The methanol oxidation activity on a Pt surface is strongly dependent on the shape of Pt particles. The near-spherical Pt nanoparticles on the SBA-15(-COOH) exhibited higher catalytic activity during methanol oxidation than Pt catalysts on unmodified SBA-15. The near-spherical Pt particles on the SBA-15(-COOH) contained large numbers of terrace sites on their surfaces, which led to high efficiency during methanol oxidation.
Language	English
Publishing date	2014-11-07
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2515664-0
ISSN	2040-3372 ; 2040-3364
ISSN (online)	2040-3372
ISSN	2040-3364
DOI	10.1039/c4nr03624g
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Article: In vitro repair of gaps in bacteriophage T7 DNA.

Lai, Y T / Masker, W

Journal of bacteriology

1998 Volume 180, Issue 23, Page(s) 6193–6202

Abstract: An in vitro system based upon extracts of Escherichia coli infected with bacteriophage T7 was used to study the mechanism of double-strand break repair. Double-strand breaks were placed in T7 genomes by cutting with a restriction endonuclease which ... ...

Abstract	An in vitro system based upon extracts of Escherichia coli infected with bacteriophage T7 was used to study the mechanism of double-strand break repair. Double-strand breaks were placed in T7 genomes by cutting with a restriction endonuclease which recognizes a unique site in the T7 genome. These molecules were allowed to repair under conditions where the double-strand break could be healed by (i) direct joining of the two partial genomes resulting from the break, (ii) annealing of complementary versions of 17-bp sequences repeated on either side of the break, or (iii) recombination with intact T7 DNA molecules. The data show that while direct joining and single-strand annealing contributed to repair of double-strand breaks, these mechanisms made only minor contributions. The efficiency of repair was greatly enhanced when DNA molecules that bridge the region of the double-strand break (referred to as donor DNA) were provided in the reaction mixtures. Moreover, in the presence of the donor DNA most of the repaired molecules acquired genetic markers from the donor DNA, implying that recombination between the DNA molecules was instrumental in repairing the break. Double-strand break repair in this system is highly efficient, with more than 50% of the broken molecules being repaired within 30 min under some experimental conditions. Gaps of 1,600 nucleotides were repaired nearly as well as simple double-strand breaks. Perfect homology between the DNA sequence near the break site and the donor DNA resulted in minor (twofold) improvement in the efficiency of repair. However, double-strand break repair was still highly efficient when there were inhomogeneities between the ends created by the double-strand break and the T7 genome or between the ends of the donor DNA molecules and the genome. The distance between the double-strand break and the ends of the donor DNA molecule was critical to the repair efficiency. The data argue that ends of DNA molecules formed by double-strand breaks are typically digested by between 150 and 500 nucleotides to form a gap that is subsequently repaired by recombination with other DNA molecules present in the same reaction mixture or infected cell.
MeSH term(s)	Bacteriophage T7/genetics ; Bacteriophage T7/metabolism ; Base Sequence ; DNA Damage ; DNA Repair ; DNA Restriction Enzymes/metabolism ; DNA, Recombinant/genetics ; DNA, Recombinant/metabolism ; DNA, Viral/genetics ; DNA, Viral/metabolism ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Escherichia coli/virology ; Genes, Viral ; Genome, Viral ; Models, Biological ; Molecular Sequence Data ; Recombination, Genetic ; Repetitive Sequences, Nucleic Acid
Chemical Substances	DNA, Recombinant ; DNA, Viral ; DNA Restriction Enzymes (EC 3.1.21.-)
Language	English
Publishing date	1998-12
Publishing country	United States
Document type	Comparative Study ; Journal Article ; Research Support, U.S. Gov't, P.H.S.
ZDB-ID	2968-3
ISSN	1098-5530 ; 0021-9193
ISSN (online)	1098-5530
ISSN	0021-9193
DOI	10.1128/JB.180.23.6193-6202.1998
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Article ; Online: Dermatomyositis is associated with an increased risk of cardiovascular and cerebrovascular events: a Taiwanese population-based longitudinal follow-up study.

Lai, Y-T / Dai, Y-S / Yen, M-F / Chen, L-S / Chen, H-H / Cooper, R G / Pan, S-L

The British journal of dermatology

2013 Volume 168, Issue 5, Page(s) 1054–1059

Abstract: Background: While the chronic inflammation related to autoimmune diseases is known to be associated with an increased cardiovascular risk, much less is known about cerebrovascular risks.: Objectives: The present population-based, age- and sex-matched ...

Abstract	Background: While the chronic inflammation related to autoimmune diseases is known to be associated with an increased cardiovascular risk, much less is known about cerebrovascular risks. Objectives: The present population-based, age- and sex-matched follow-up study was undertaken to investigate the risks of acute myocardial infarction (AMI) and ischaemic stroke in patients with dermatomyositis (DMS). Methods: In total 907 patients with DMS were enrolled and compared with a non-DMS control group consisting of 4535 age- and sex-matched, randomly sampled subjects without DMS. The AMI-free and ischaemic stroke-free survival curves were generated using the Kaplan-Meier method. Cox proportional hazard regression was used to estimate the DMS-associated risks of AMI and ischaemic stroke. Results: During the 2-year follow-up period, 14 patients with DMS (1.5%) and 18 patients in the non-DMS control group (0.4%) suffered AMIs. The crude hazard ratio (HR) for suffering an AMI in patients with DMS compared with subjects in the non-DMS group was 3.96 [95% confidence interval (CI) 1.97-7.96, P = 0.0001], while the adjusted HR was 3.37 (95% CI 1.67-6.80, P = 0.0007), after taking into account demographic characteristics and cardiovascular comorbidities. During the same follow-up period, 46 patients (5.1%) and 133 subjects in the control group (2.9%) developed ischaemic strokes. The crude HR for developing an ischaemic stroke in patients with DMS compared with subjects in the non-DMS group was 1.78 (95% CI 1.27-2.49, P = 0.0007), and the adjusted HR was 1.67 (95% CI, 1.19-2.34, P = 0.0028). Conclusions: These findings suggest that DMS is associated with an increased risk of cardiovascular and cerebrovascular events.
MeSH term(s)	Adult ; Aged ; Asians ; Cardiovascular Diseases/epidemiology ; Cardiovascular Diseases/etiology ; Dermatomyositis/complications ; Dermatomyositis/epidemiology ; Female ; Follow-Up Studies ; Humans ; Longitudinal Studies ; Male ; Middle Aged ; Risk Factors ; Stroke/epidemiology ; Stroke/etiology ; Taiwan/epidemiology
Language	English
Publishing date	2013-01-30
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	80076-4
ISSN	1365-2133 ; 0007-0963
ISSN (online)	1365-2133
ISSN	0007-0963
DOI	10.1111/bjd.12245
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Article: Complications in patients with palmar hyperhidrosis treated with transthoracic endoscopic sympathectomy.

Lai, Y T / Yang, L H / Chio, C C / Chen, H H

Neurosurgery

1997 Volume 41, Issue 1, Page(s) 110–3; discussion 113–5

Abstract: Objective: To assess the complications in a group of patients with palmar hyperhidrosis treated with transthoracic endoscopic sympathectomy. The extraordinarily high incidence of postoperative compensatory hyperhidrosis in our series is stressed and ... ...

Abstract	Objective: To assess the complications in a group of patients with palmar hyperhidrosis treated with transthoracic endoscopic sympathectomy. The extraordinarily high incidence of postoperative compensatory hyperhidrosis in our series is stressed and explained. Methods: The retrospective study included chart reviews and outpatient assessments. Seventy-two patients underwent T2 or T2-T3 endoscopic sympathectomy for primary palmar hyperhidrosis. Patients' hyperhidrosis severity, precipitating factors, postoperative complications, surgical results, and satisfaction were assessed. Severity of palmar hyperhidrosis and compensatory hyperhidrosis was classified by two grading scales. Results: The success rate of sympathectomy was 93%. All patients except one suffered from compensatory sweating, which was the main cause of patients' dissatisfaction postoperatively. Seventeen percent of the patients (12 of 72 patients) experienced new symptoms of gustatory sweating (facial sweating associated with eating). Twenty-one patients experienced other complications, including pneumothorax, Horner's syndrome, nasal obstruction, and intercostal neuralgia. Conclusion: Transthoracic endoscopic sympathectomy is an effective and simple modality to treat palmar hyperhidrosis. However, all patients need to be warned of the common complications, particularly compensatory hyperhidrosis, before surgery.
MeSH term(s)	Adult ; Endoscopes ; Female ; Follow-Up Studies ; Hand/innervation ; Horner Syndrome/etiology ; Humans ; Hyperhidrosis/surgery ; Intercostal Nerves/injuries ; Male ; Nasal Obstruction/etiology ; Neuralgia/etiology ; Patient Satisfaction ; Pneumothorax/etiology ; Postoperative Complications/etiology ; Sweating/physiology ; Sweating, Gustatory/etiology ; Sympathectomy/instrumentation ; Thoracoscopes
Language	English
Publishing date	1997-07
Publishing country	United States
Document type	Journal Article
ZDB-ID	135446-2
ISSN	1524-4040 ; 0148-396X
ISSN (online)	1524-4040
ISSN	0148-396X
DOI	10.1097/00006123-199707000-00023
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Zs.A 1424: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 539: Show issues

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Article: Activin receptor-like kinase 2 can mediate atrioventricular cushion transformation.

Lai, Y T / Beason, K B / Brames, G P / Desgrosellier, J S / Cleggett, M C / Shaw, M V / Brown, C B / Barnett, J V

Developmental biology

2000 Volume 222, Issue 1, Page(s) 1–11

Abstract: Epithelial-mesenchymal transformation in the atrioventricular (AV) cushion of the tubular heart is a critical step in the formation of the valves and membranous septa. Transforming growth factor beta (TGFbeta) ligands are a primary signal of this ... ...

Abstract	Epithelial-mesenchymal transformation in the atrioventricular (AV) cushion of the tubular heart is a critical step in the formation of the valves and membranous septa. Transforming growth factor beta (TGFbeta) ligands are a primary signal of this transformation. To investigate the expression and function of specific Type I TGFbeta receptors during AV cushion transformation, we cloned and characterized the chicken homologues of two mammalian activin receptor-like kinases (ALK), ALK2 and ALK5, and generated specific, polyclonal antibodies against the extracellular binding domains of each. Both the chicken ALK2 (ChALK2) and the chicken ALK5 (ChALK5) cDNAs encode proteins that bind TGFbeta1 in the presence of the Type II TGFbeta receptor. However, as expected, only ChALK5 stimulated the TGFbeta-responsive PAI-1 promoter. These data establish that ChALK2 and ChALK5 are the chicken homologues of the mammalian receptors ALK2 and ALK5. Both ChALK2 and ChALK5 are expressed by AV endocardial cells. AV cushion explants harvested from stage 13-18 embryos were incubated with antisera to ChALK2 or ChALK5. Anti-ChALK2 antisera inhibited mesenchyme formation by 34-50% while neutralizing anti-ChALK5 antisera were without effect. These data demonstrate that ChALK2 can mediate transformation in the AV cushion.
MeSH term(s)	Activin Receptors, Type II ; Amino Acid Sequence ; Animals ; Atrioventricular Node/embryology ; Base Sequence ; COS Cells ; Chick Embryo ; DNA Primers ; DNA, Complementary ; Immune Sera ; Molecular Sequence Data ; Morphogenesis ; Protein-Serine-Threonine Kinases/chemistry ; Protein-Serine-Threonine Kinases/genetics ; Protein-Serine-Threonine Kinases/metabolism ; Receptors, Growth Factor/chemistry ; Receptors, Growth Factor/genetics ; Receptors, Growth Factor/metabolism ; Sequence Homology, Amino Acid
Chemical Substances	DNA Primers ; DNA, Complementary ; Immune Sera ; Receptors, Growth Factor ; Protein-Serine-Threonine Kinases (EC 2.7.11.1) ; Activin Receptors, Type II (EC 2.7.11.30)
Language	English
Publishing date	2000-06-01
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, P.H.S.
ZDB-ID	1114-9
ISSN	1095-564X ; 0012-1606
ISSN (online)	1095-564X
ISSN	0012-1606
DOI	10.1006/dbio.2000.9698
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Article ; Online: First Measurement of the B^{+}→π^{+}π^{0}π^{0} Branching Fraction and CP Asymmetry.

Lai, Y-T / Adachi, I / Aihara, H / Al Said, S / Asner, D M / Atmacan, H / Aulchenko, V / Aushev, T / Ayad, R / Babu, V / Bahinipati, S / Behera, P / Belous, K / Bennett, J / Bessner, M / Bhuyan, B / Bilka, T / Bobrov, A / Borah, J /

Bozek, A / Bračko, M / Branchini, P / Browder, T E / Budano, A / Campajola, M / Červenkov, D / Chang, M-C / Chang, P / Chekelian, V / Chen, A / Cheon, B G / Chilikin, K / Cho, H E / Cho, K / Cho, S-J / Choi, S-K / Choi, Y / Cinabro, D / Cunliffe, S / Czank, T / Das, S / De Nardo, G / De Pietro, G / Dhamija, R / Di Capua, F / Dingfelder, J / Doležal, Z / Dong, T V / Ferber, T / Fulsom, B G / Garg, R / Gaur, V / Gabyshev, N / Giri, A / Goldenzweig, P / Graziani, E / Gu, T / Guan, Y / Gudkova, K / Hadjivasiliou, C / Halder, S / Hartbrich, O / Hayasaka, K / Hayashii, H / Higuchi, T / Hou, W-S / Hsu, C-L / Iijima, T / Inami, K / Ishikawa, A / Itoh, R / Iwasaki, M / Iwasaki, Y / Jacobs, W W / Jang, E-J / Jia, S / Jin, Y / Kaliyar, A B / Kang, K H / Kim, C H / Kim, D Y / Kim, K-H / Kim, Y-K / Kinoshita, K / Kodyš, P / Konno, T / Korobov, A / Korpar, S / Kovalenko, E / Križan, P / Krokovny, P / Kumar, M / Kumar, R / Kumara, K / Kuzmin, A / Kwon, Y-J / Lam, T / Lange, J S / Laurenza, M / Lee, S C / Levit, D / Li, J / Li, L K / Li, Y B / Li Gioi, L / Libby, J / Lieret, K / Liventsev, D / Martini, A / Masuda, M / Matvienko, D / Meier, F / Merola, M / Metzner, F / Mizuk, R / Mohanty, G B / Moon, T J / Mrvar, M / Mussa, R / Nakao, M / Natochii, A / Nayak, L / Nisar, N K / Nishida, S / Ogawa, S / Pakhlova, G / Pang, T / Pardi, S / Park, H / Park, S-H / Passeri, A / Patra, S / Paul, S / Pedlar, T K / Pestotnik, R / Piilonen, L E / Podobnik, T / Prencipe, E / Prim, M T / Rostomyan, A / Rout, N / Russo, G / Sahoo, D / Sakai, Y / Sandilya, S / Sangal, A / Santelj, L / Sanuki, T / Savinov, V / Schnell, G / Schueler, J / Schwanda, C / Seino, Y / Senyo, K / Sevior, M E / Shapkin, M / Sharma, C / Shen, C P / Shiu, J-G / Singh, J B / Sokolov, A / Solovieva, E / Starič, M / Stottler, Z S / Strube, J F / Sumihama, M / Sumisawa, K / Sutcliffe, W / Takizawa, M / Tamponi, U / Tanida, K / Tenchini, F / Trabelsi, K / Uglov, T / Unno, Y / Uno, K / Uno, S / Urquijo, P / van Tonder, R / Varner, G / Varvell, K E / Vinokurova, A / Vossen, A / Waheed, E / Wang, C H / Wang, X L / Watanabe, M / Watanuki, S / Won, E / Yabsley, B D / Yan, W / Yang, S B / Ye, H / Yelton, J / Zhai, Y / Zhang, Z P / Zhilich, V / Zhukova, V

Physical review letters

2023 Volume 130, Issue 18, Page(s) 181804

Abstract: We study B^{+}→π^{+}π^{0}π^{0} using 711 fb^{-1} of data collected at the ϒ(4S) resonance with the Belle detector at the KEKB asymmetric-energy e^{+}e^{-} collider. We measure an inclusive branching fraction of (19.0±1.5±1.4)×10^{-6} and an inclusive CP ...

Abstract	We study B^{+}→π^{+}π^{0}π^{0} using 711 fb^{-1} of data collected at the ϒ(4S) resonance with the Belle detector at the KEKB asymmetric-energy e^{+}e^{-} collider. We measure an inclusive branching fraction of (19.0±1.5±1.4)×10^{-6} and an inclusive CP asymmetry of (9.2±6.8±0.7)%, where the first uncertainties are statistical and the second are systematic, and a B^{+}→ρ(770)^{+}π^{0} branching fraction of (11.2±1.1±0.9_{-1.6}^{+0.8})×10^{-6}, where the third uncertainty is due to possible interference with B^{+}→ρ(1450)^{+}π^{0}. We present the first observation of a structure around 1 GeV/c^{2} in the π^{0}π^{0} mass spectrum, with a significance of 6.4σ, and measure a branching fraction to be (6.9±0.9±0.6)×10^{-6}. We also report a measurement of local CP asymmetry in this structure.
Language	English
Publishing date	2023-03-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	208853-8
ISSN	1079-7114 ; 0031-9007
ISSN (online)	1079-7114
ISSN	0031-9007
DOI	10.1103/PhysRevLett.130.181804
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Article ; Online: Measurement of Two-Particle Correlations of Hadrons in e^{+}e^{-} Collisions at Belle.

Chen, Y-C / Lee, Y-J / Chang, P / Adachi, I / Aihara, H / Al Said, S / Asner, D M / Aushev, T / Ayad, R / Babu, V / Behera, P / Belous, K / Bennett, J / Bessner, M / Bilka, T / Bodrov, D / Borah, J / Bračko, M / Branchini, P /

Browder, T E / Budano, A / Campajola, M / Červenkov, D / Chang, M-C / Chekelian, V / Cheon, B G / Chilikin, K / Cho, H E / Cho, K / Cho, S-J / Choi, S-K / Choi, Y / Cinabro, D / Das, S / De Nardo, G / De Pietro, G / Dhamija, R / Di Capua, F / Dingfelder, J / Dong, T V / Dossett, D / Epifanov, D / Ferber, T / Fulsom, B G / Garg, R / Gaur, V / Giri, A / Goldenzweig, P / Gu, T / Gudkova, K / Hadjivasiliou, C / Hartbrich, O / Hayasaka, K / Hayashii, H / Hou, W-S / Hsu, C-L / Iijima, T / Inami, K / Ishikawa, A / Itoh, R / Iwasaki, M / Iwasaki, Y / Jacobs, W W / Jia, S / Jin, Y / Kaliyar, A B / Kim, C H / Kim, D Y / Kim, K-H / Kim, Y-K / Kodyš, P / Konno, T / Korobov, A / Korpar, S / Kovalenko, E / Križan, P / Kroeger, R / Krokovny, P / Kumar, M / Kumar, R / Kumara, K / Kuzmin, A / Kwon, Y-J / Lai, Y-T / Lam, T / Lange, J S / Laurenza, M / Lee, S C / Li, J / Li, Y / Li, Y B / Li Gioi, L / Libby, J / Lieret, K / Lin, C-W / Liventsev, D / Martini, A / Masuda, M / Matsuda, T / Matvienko, D / Meier, F / Merola, M / Metzner, F / Miyabayashi, K / Mohanty, G B / Moon, T J / Mussa, R / Nakao, M / Natochii, A / Nayak, L / Nisar, N K / Nishida, S / Nishimura, K / Ogawa, S / Ono, H / Pakhlova, G / Pang, T / Pardi, S / Park, S-H / Patra, S / Paul, S / Pedlar, T K / Piilonen, L E / Podobnik, T / Prencipe, E / Prim, M T / Rout, N / Russo, G / Sahoo, D / Sandilya, S / Sangal, A / Santelj, L / Sanuki, T / Savinov, V / Schnell, G / Schwanda, C / Seidl, R / Seino, Y / Sevior, M E / Shapkin, M / Shiu, J-G / Singh, J B / Sokolov, A / Solovieva, E / Starič, M / Stottler, Z S / Sumihama, M / Sumisawa, K / Sutcliffe, W / Takizawa, M / Tamponi, U / Tanida, K / Tenchini, F / Uchida, M / Uglov, T / Unno, Y / Uno, K / Uno, S / Van Tonder, R / Varner, G / Vinokurova, A / Vossen, A / Waheed, E / Wang, C H / Wang, D / Wang, E / Wang, X L / Watanuki, S / Won, E / Yan, W / Yang, S B / Ye, H / Yelton, J / Zhai, Y / Zhang, Z P / Zhilich, V / Zhukova, V

Physical review letters

2022 Volume 128, Issue 14, Page(s) 142005

Abstract: The measurement of two-particle angular correlation functions in high-multiplicity e^{+}e^{-} collisions at sqrt[s]=10.52 GeV is reported. In this study, the 89.5 fb^{-1} of hadronic e^{+}e^{-} annihilation data collected by the Belle detector at KEKB ... ...

Abstract	The measurement of two-particle angular correlation functions in high-multiplicity e^{+}e^{-} collisions at sqrt[s]=10.52 GeV is reported. In this study, the 89.5 fb^{-1} of hadronic e^{+}e^{-} annihilation data collected by the Belle detector at KEKB are used. Two-particle angular correlation functions are measured in the full relative azimuthal angle (Δϕ) and three units of pseudorapidity (Δη), defined by either the electron beam axis or the event-shape thrust axis, and are studied as a function of charged-particle multiplicity. The measurement in the thrust axis analysis, with mostly outgoing quark pairs determining the reference axis, is sensitive to the region of additional soft gluon emissions. No significant anisotropic collective behavior is observed with either coordinate analyses. Near-side jet correlations appear to be absent in the thrust axis analysis. The measurements are compared to predictions from various event generators and are expected to provide new constraints to the phenomenological models in the low-energy regime.
Language	English
Publishing date	2022-04-27
Publishing country	United States
Document type	Journal Article
ZDB-ID	208853-8
ISSN	1079-7114 ; 0031-9007
ISSN (online)	1079-7114
ISSN	0031-9007
DOI	10.1103/PhysRevLett.128.142005
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