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  1. Article ; Online: Evaluating the efficacy of self-study videos for the surgery clerkship rotation: an innovative project in undergraduate surgical education.

    Mookerji, Nikhile / El-Haddad, Julie / Vo, Thin Xuan / Grose, Elysia / Seabrook, Christine / Lam, Buu-Khanh / Feibel, Robert / Bennett, Sean

    Canadian journal of surgery. Journal canadien de chirurgie

    2021  Volume 64, Issue 4, Page(s) E428–E434

    Abstract: Background: Educational videos have become valuable resources and can address some of the pitfalls of traditional learning. To ensure clerkship students have adequate exposure to curriculum objectives, a series of objective-aligned self-directed ... ...

    Abstract Background: Educational videos have become valuable resources and can address some of the pitfalls of traditional learning. To ensure clerkship students have adequate exposure to curriculum objectives, a series of objective-aligned self-directed learning video podcasts covering core surgical concepts were developed by medical students and surgical residents. The objective of the study was to evaluate the efficacy of the video podcasts in the surgery clerkship rotation.
    Methods: Nineteen video podcasts were created, housed at www.surgicaleducationportal.com, and distributed to third-year medical students completing their surgical clerkship. A 10-question multiple-choice quiz was administered before and after students viewed each video, and they were also asked to complete a satisfaction survey.
    Results: A total of 302 paired pretests and posttests were completed. There was a mean increase of 2.7 points in posttest scores compared with pretest scores (p < 0.001). On a Likert scale from 1 to 5, with 5 being excellent, students rated the usefulness of the videos as 4.3, the quality of the content as 4.3 and the quality of the video as 4.2. Ninety-eight percent of students would recommend these videos to their classmates.
    Conclusion: Video podcasts are an effective modality for engaging medical students and may improve standardization of learning during their surgical clerkship.
    MeSH term(s) Attitude of Health Personnel ; Clinical Clerkship ; Education, Medical, Undergraduate ; Educational Measurement ; General Surgery/education ; Humans ; Ontario ; Orthopedics/education ; Students, Medical ; Urology/education ; Webcasts as Topic
    Language English
    Publishing date 2021-07-29
    Publishing country Canada
    Document type Evaluation Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 410651-9
    ISSN 1488-2310 ; 0008-428X
    ISSN (online) 1488-2310
    ISSN 0008-428X
    DOI 10.1503/cjs.019019
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  2. Article ; Online: Development of Mitral Stenosis After Mitral Valve Repair: Importance of Mitral Valve Area.

    Chan, Kwan Leung / Chen, Shin-Yee / Mesana, Thierry / Lam, Buu Khanh

    The Canadian journal of cardiology

    2017  

    Abstract: Background: The development of mitral stenosis (MS) is not uncommon after mitral valve (MV) repair for degenerative mitral regurgitation (MR), but the significance of MS in this setting has not been defined.: Methods: We prospectively studied 110 ... ...

    Abstract Background: The development of mitral stenosis (MS) is not uncommon after mitral valve (MV) repair for degenerative mitral regurgitation (MR), but the significance of MS in this setting has not been defined.
    Methods: We prospectively studied 110 such patients who underwent supine bicycle exercise testing to assess intracardiac hemodynamics at rest and at peak exercise. B-type natriuretic peptide (BNP) levels were measured at rest and after the exercise test. The patients also performed the 6-minute walk test and completed the 36-Item Short Form Survey (SF-36). Follow-up was performed by a review of the medical record and telephone interview.
    Results: Of 110 patients, 22 had MS defined by a mitral valve area (MVA) ≤ 1.5 cm
    Conclusions: In patients who had MV repair for degenerative MR, an MVA ≤ 1.5 cm
    Language English
    Publishing date 2017-09-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 632813-1
    ISSN 1916-7075 ; 0828-282X
    ISSN (online) 1916-7075
    ISSN 0828-282X
    DOI 10.1016/j.cjca.2017.08.027
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  3. Article ; Online: Transfemoral Edwards SAPIEN aortic valve implantation through aortofemoral endograft.

    Chandrasekhar, Jaya / Lam, Buu-Khanh / Glover, Chris

    The Canadian journal of cardiology

    2014  Volume 30, Issue 9, Page(s) 1108.e5–7

    Abstract: We present the case of an 86-year-old woman with an aortobifemoral endograft and porcelain aorta who underwent transfemoral transcatheter aortic valve implantation (TAVI). A femoral cutdown was performed to the left limb of the endograft, and the needle ... ...

    Abstract We present the case of an 86-year-old woman with an aortobifemoral endograft and porcelain aorta who underwent transfemoral transcatheter aortic valve implantation (TAVI). A femoral cutdown was performed to the left limb of the endograft, and the needle puncture into the graft required sequential incisions and dilation to allow access of the 18F Edwards SAPIEN expandable eSheath (Edwards Lifesciences, Irvine, CA). A 26-mm Edwards SAPIEN transcatheter aortic valve was then successfully deployed. The cutdown was closed and hemostasis was achieved without any iatrogenic narrowing of the graft. Transfemoral TAVI through surgical cutdown with dilation of a femoral endograft is safe and feasible.
    MeSH term(s) Aged, 80 and over ; Aorta/surgery ; Aortic Valve/surgery ; Aortic Valve Stenosis/surgery ; Blood Vessel Prosthesis ; Catheters ; Female ; Femoral Artery/surgery ; Heart Valve Prosthesis ; Humans ; Prosthesis Implantation/methods
    Language English
    Publishing date 2014-09
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 632813-1
    ISSN 1916-7075 ; 0828-282X
    ISSN (online) 1916-7075
    ISSN 0828-282X
    DOI 10.1016/j.cjca.2014.02.004
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  4. Article ; Online: Atrial fibrillation therapies: lest we forget surgery.

    Toeg, Hadi Daood / Al-Atassi, Talal / Lam, Buu-Khanh

    The Canadian journal of cardiology

    2014  Volume 30, Issue 6, Page(s) 590–597

    Abstract: Atrial fibrillation (AF) is a disease that causes a significant burden in a patient's life. It is a known risk factor for heart failure, stroke, and premature death. The classic therapeutic strategies include rate control, rhythm control, and prevention ... ...

    Abstract Atrial fibrillation (AF) is a disease that causes a significant burden in a patient's life. It is a known risk factor for heart failure, stroke, and premature death. The classic therapeutic strategies include rate control, rhythm control, and prevention of stroke. Pharmacological rhythm control with antiarrhythmic drugs can only be achieved 50% of the time while simultaneously subjecting patients to deleterious adverse reactions. With recent advances in catheter ablation procedures, rhythm control can be safely attained anywhere from 57%-80% of the time, depending on the number of repeat catheter ablation procedures that are performed and concomitant use of antiarrhythmic drugs. The Cox-Maze procedure is a technically challenging cut-and-sew atrial lesion set with associated morbidity, yet is still considered the gold standard for rhythm control. Fortunately, this procedure has been modified in efforts to improve the safety profile (shorter cross clamp and cardiopulmonary bypass time), to simplify lesion set creation with newer energy sources, and to perform this operation in a minimally invasive setting. Minimally invasive surgical AF ablation techniques have excellent safety profiles and can achieve rhythm control in up to 90% of patients. In contrast, patients undergoing open heart surgery can undergo either concomitant endocardial or epicardial AF ablation procedures without jeopardizing the surgery along with success rates from 60% to 88%. Thus, there has been an increase in current surgical options for treating AF because of novel approaches and energy sources which yield effective long-term results in patient care and minimize perioperative complications and thereby optimize the risk/benefit ratio profile.
    MeSH term(s) Ablation Techniques ; Anti-Arrhythmia Agents/therapeutic use ; Anticoagulants/therapeutic use ; Atrial Appendage/surgery ; Atrial Fibrillation/classification ; Atrial Fibrillation/physiopathology ; Atrial Fibrillation/therapy ; Cardiac Surgical Procedures/methods ; Humans ; Microwaves/therapeutic use ; Stroke/prevention & control
    Chemical Substances Anti-Arrhythmia Agents ; Anticoagulants
    Language English
    Publishing date 2014-06
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 632813-1
    ISSN 1916-7075 ; 0828-282X
    ISSN (online) 1916-7075
    ISSN 0828-282X
    DOI 10.1016/j.cjca.2014.02.001
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  5. Article ; Online: Simulation-Based Skill Training for Trainees in Cardiac Surgery: A Systematic Review.

    Ribeiro, Igo B / Ngu, Janet M C / Lam, Buu-Khanh / Edwards, Roger A

    The Annals of thoracic surgery

    2017  Volume 105, Issue 3, Page(s) 972–982

    Abstract: Background: Simulation-based training has been an important part of the solution to address the shortfalls in cardiac surgery training. This review was conducted to identify and systematically summarize existing evidence on outcomes and methodological ... ...

    Abstract Background: Simulation-based training has been an important part of the solution to address the shortfalls in cardiac surgery training. This review was conducted to identify and systematically summarize existing evidence on outcomes and methodological quality of simulation-based skills training for cardiac surgery trainees.
    Methods: MEDLINE, Embase, and ERIC (Education Resources Information Center) databases were searched. Studies included peer-reviewed publications with simulation-based skill training in cardiac surgery programs with outcome measures of performance. Data extraction covered the type of skills training, simulator type and fidelity, the level of trainees, assessment tools, assessors, study design and its components, strengths and limitations, and elements required for the Medical Education Research Study Quality Instrument score. The review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.
    Results: Of 16 studies that met the criteria, only four (25%) randomized controlled trials were identified, and the remaining were observational studies. Seven observational studies (43.7%) were single-group pre-post tests. The mean number of trainees was 20.4 (SD, 14.1). Low-fidelity simulators were used in 13 studies (81.2%). Most of the studies (81.3%) were high quality based on a Medical Education Research Study Quality Instrument score of 12 or more. Evidence of assessment tool validation was absent among all studies. No study outcome measures were directed to skills transfer to the operating room or patient outcomes. Overall learning outcomes' effect sizes were consistently high (2.2; SD, 1.6), with junior residents benefitting most (effect size, 2.8; SD, 2.2) CONCLUSIONS: Simulation-based skill training is associated with improved learning outcomes for cardiac surgery trainees with large effect sizes, but more behavior-level outcomes are required to fully assess its value.
    MeSH term(s) Cardiac Surgical Procedures/education ; Clinical Competence ; Humans ; Simulation Training
    Language English
    Publishing date 2017-12-14
    Publishing country Netherlands
    Document type Journal Article ; Systematic Review
    ZDB-ID 211007-6
    ISSN 1552-6259 ; 0003-4975
    ISSN (online) 1552-6259
    ISSN 0003-4975
    DOI 10.1016/j.athoracsur.2017.11.036
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  6. Article ; Online: Impact of visualization on simulation training for vascular anastomosis.

    Malas, Tarek / Al-Atassi, Talal / Brandys, Tim / Naik, Viren / Lapierre, Harry / Lam, Buu-Khanh

    The Journal of thoracic and cardiovascular surgery

    2017  Volume 155, Issue 4, Page(s) 1686–1693.e5

    Abstract: Objective: There is mounting evidence supporting the benefit of surgical simulation on the learning of skills independently and in a patient-safe environment. The objective of this study was to examine the effect of visualization of surgical steps via ... ...

    Abstract Objective: There is mounting evidence supporting the benefit of surgical simulation on the learning of skills independently and in a patient-safe environment. The objective of this study was to examine the effect of visualization of surgical steps via instructional media on performance of an end-to-side microvascular anastomosis.
    Methods: Thirty-two first- and second-year surgical trainees from the University of Ottawa received an expert-guided, didactic lecture on vascular anastomosis and performed an end-to-side anastomosis on a procedural model to assess baseline skills. Assessments were performed by 2 blinded, expert observers using validated measurements of skill. Subjects were then proctored to perform anastomoses using the model. Subjects were then randomized to watch an instructional video on performance of vascular anastomosis using visualization as the education strategy. One week later, subjects were again assessed for technical skill on the model. The primary outcome was the score achieved on the Objective Structured Assessment of Technical Skill (OSATS) scale. Secondary outcomes included an anastomosis-specific End-Product Rating Score and time to completion.
    Results: Compared with residents who received expert-guided simulator training alone, those who used the supplementary multimedia scored significantly greater on OSATS (17.4 ± 2.9 vs 14.2 ± 3.2, P = .0013) and on End-Product Rating Score (11.24 ± 3.0 vs 7.4 ± 4.1, P = .011). However, performance time did not differ between groups (15.7 vs 14.3 minutes, P = .79).
    Conclusions: Residents with supplemental instructional media performed an end-to-side anastomosis more proficiently as assessed by OSATS and with a greater quality end-product. This suggests that both didactic simulation training as well as use of visualization multimedia improves learning and performance of vascular anastomosis and should be incorporated into surgical curricula.
    MeSH term(s) Anastomosis, Surgical/education ; Clinical Competence ; Curriculum ; Education, Medical, Graduate/methods ; Educational Measurement ; Educational Status ; Humans ; Ontario ; Simulation Training ; Single-Blind Method ; Task Performance and Analysis ; Vascular Surgical Procedures/education ; Video Recording ; Visual Perception
    Keywords covid19
    Language English
    Publishing date 2017-11-09
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial ; Video-Audio Media
    ZDB-ID 3104-5
    ISSN 1097-685X ; 0022-5223
    ISSN (online) 1097-685X
    ISSN 0022-5223
    DOI 10.1016/j.jtcvs.2017.10.080
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  7. Article ; Online: Mapping and ablation of autonomic ganglia in prevention of postoperative atrial fibrillation in coronary surgery: MAAPPAFS atrial fibrillation randomized controlled pilot study.

    Al-Atassi, Talal / Toeg, Hadi / Malas, Tarek / Lam, Buu-Khanh

    The Canadian journal of cardiology

    2014  Volume 30, Issue 10, Page(s) 1202–1207

    Abstract: Background: Postoperative atrial fibrillation (POAF) remains common after coronary artery bypass grafting (CABG). Limited efforts to intervene on cardiac autonomic ganglionic plexi (AGP) during surgery show mixed results. In this pilot study, we ... ...

    Abstract Background: Postoperative atrial fibrillation (POAF) remains common after coronary artery bypass grafting (CABG). Limited efforts to intervene on cardiac autonomic ganglionic plexi (AGP) during surgery show mixed results. In this pilot study, we evaluated the safety and feasibility of map-guided ablation of AGPs during isolated CABG in the prevention of POAF.
    Methods: In this pilot study, patients undergoing isolated CABG were randomized into an intervention group (mapping and ablation of AGP [AGP+] group), and a control group (no mapping and ablation [AGP-] group). Using high-frequency stimulation, active AGPs were identified and ablated intraoperatively using radiofrequency. Continuous rhythm monitoring, serum electrolytes, postoperative medications, and postoperative complications were recorded until discharge.
    Results: Randomization of 47 patients (24 AGP+ and 23 AGP-) resulted in similar baseline characteristics, past medical history, and preoperative medication use. The intervention added a median of 14 minutes to the operative time. The incidence of POAF, mean time in POAF, and median length of stay in hospital were: AGP+ 21% vs AGP- 30%; AGP+ 298 minutes vs AGP- 514 minutes; AGP+ 5 days vs AGP- 6 days; respectively). Postoperative complications, medication use, and daily serum electrolyte profiles were similar in both groups.
    Conclusions: This pilot study demonstrated the safety and feasibility of mapping and ablation of AGP during CABG with minimal added operative time. Results further suggest a potentially clinically significant effect on POAF. A multicentre trial is warranted.
    MeSH term(s) Atrial Fibrillation/prevention & control ; Catheter Ablation ; Coronary Artery Bypass/adverse effects ; Feasibility Studies ; Ganglia, Autonomic/surgery ; Humans ; Intraoperative Period ; Length of Stay ; Pilot Projects ; Postoperative Complications/therapy
    Language English
    Publishing date 2014-10
    Publishing country England
    Document type Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
    ZDB-ID 632813-1
    ISSN 1916-7075 ; 0828-282X
    ISSN (online) 1916-7075
    ISSN 0828-282X
    DOI 10.1016/j.cjca.2014.04.018
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  8. Article ; Online: Transfemoral vs Non-transfemoral Access for Transcatheter Aortic Valve Implantation: A Systematic Review and Meta-analysis.

    Chandrasekhar, Jaya / Hibbert, Benjamin / Ruel, Marc / Lam, Buu-Khanh / Labinaz, Marino / Glover, Christopher

    The Canadian journal of cardiology

    2015  Volume 31, Issue 12, Page(s) 1427–1438

    Abstract: Background: Transcatheter aortic valve implantation (TAVI) is the definitive therapy for high-risk patients with severe aortic stenosis. The aim of this study was to determine the effect of non-transfemoral access on clinical outcomes in TAVI.: ... ...

    Abstract Background: Transcatheter aortic valve implantation (TAVI) is the definitive therapy for high-risk patients with severe aortic stenosis. The aim of this study was to determine the effect of non-transfemoral access on clinical outcomes in TAVI.
    Methods: We conducted a computerized literature search on SCOPUS and selected all studies published in the English language, from 2002 until March 12 2014, that compared transfemoral access with a non-transfemoral access cohort. Two independent reviewers evaluated the studies and extracted data for analysis.
    Results: A total 17,020 patients (11,079 transfemoral, 5941 non-transfemoral) encompassing 28 studies underwent TAVI between 2007 to 2013. Overall, the 30-day mortality was 4.7% with the transfemoral approach and 8.1% with a non-transfemoral approach (odds ratio [OR], 0.56; 95% confidence interval [CI], 0.49-0.64; P < 0.01). The 1-year mortality was 16.4% with transfemoral access and 24.8% with non-transfemoral access (OR, 0.68; 95% CI, 0.60-0.75; P < 0.01). Transfemoral access was associated with a greater incidence of vascular complications (OR, 2.1; 95% CI, 1.48-2.99; P < 0.01) but a lower rate of surgical conversion (OR, 0.59; 95% CI, 0.42-0.81; P < 0.01) and similar bleeding (OR, 1.01; 95% CI, 0.81-1.27; P = 0.91) compared with non-transfemoral access. The incidence of cerebrovascular events was similar in both groups (1.6% vs 2.1%; OR, 0.86; 95% CI, 0.64-1.15; P = 0.31).
    Conclusions: Transfemoral access was associated with lower rate of 30-day and 1-year mortality compared with non-transfemoral access for TAVI. Randomized studies are needed to ascertain the effect of alternative access sites on clinical outcomes in prohibitive-risk, high-risk, and intermediate-risk populations, using currently available technologies.
    MeSH term(s) Adult ; Aortic Valve/surgery ; Bicuspid Aortic Valve Disease ; Cardiac Catheterization/methods ; Cause of Death ; Cohort Studies ; Female ; Femoral Artery ; Heart Defects, Congenital/mortality ; Heart Defects, Congenital/surgery ; Heart Valve Diseases/mortality ; Heart Valve Diseases/surgery ; Heart Valve Prosthesis Implantation/methods ; Humans ; Male ; Postoperative Complications/mortality ; Risk Factors ; Survival Rate
    Language English
    Publishing date 2015-04-30
    Publishing country England
    Document type Comparative Study ; Journal Article ; Meta-Analysis ; Review ; Systematic Review
    ZDB-ID 632813-1
    ISSN 1916-7075 ; 0828-282X
    ISSN (online) 1916-7075
    ISSN 0828-282X
    DOI 10.1016/j.cjca.2015.04.023
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  9. Article ; Online: Should We Ablate Atrial Fibrillation During Coronary Artery Bypass Grafting and Aortic Valve Replacement?

    Al-Atassi, Talal / Kimmaliardjuk, Donna-May / Dagenais, Camille / Bourke, Michael / Lam, Buu-Khanh / Rubens, Fraser D

    The Annals of thoracic surgery

    2017  Volume 104, Issue 2, Page(s) 515–522

    Abstract: Background: This study evaluates the safety and efficacy of concomitant atrial fibrillation (AF) ablation in patients with AF undergoing coronary artery bypass grafting (CABG) or aortic valve replacement (AVR) or both.: Methods: This is a single- ... ...

    Abstract Background: This study evaluates the safety and efficacy of concomitant atrial fibrillation (AF) ablation in patients with AF undergoing coronary artery bypass grafting (CABG) or aortic valve replacement (AVR) or both.
    Methods: This is a single-center retrospective study of patients with AF presenting for CABG or AVR or both between 2009 and 2013. They were divided into an ablation group that underwent concomitant AF ablation and a control group that did not. Follow-up data were obtained using telephone interviews. The data were 100% complete with a median follow-up of 30 months.
    Results: A total of 375 patients with AF presented for CABG (44%), AVR (27%), or CABG and AVR (29%). The ablation (129 patients) and control (246 patients) groups had similar baseline characteristics. The ablation group had significantly longer cardiopulmonary bypass and cross-clamp times, adding a mean of 31 ± 3 and 22 ± 3 minutes (p < 0.01 for both), respectively. There were similar unadjusted rates of hospital mortality (4.7% versus 5.3%, p = 0.79), stroke (3.1% versus 3.3%, p = 0.94), and reopening (4.7% versus 6.5%, p = 0.46) between the groups. The intensive care and hospital length of stays were similar. The ablation group had a lower incidence of postoperative AF (27% versus 78%, p < 0.01). Adjusted operative mortality was similar, but the intervention group had significantly lower odds of postoperative AF (odds ratio 0.11, p < 0.01). Although there was no difference in mid-term survival, the ablation group had higher mid-term AF-free survival (p < 0.01) and a trend toward higher anticoagulation-free (p = 0.09) and stroke-free survival (p = 0.08).
    Conclusions: Concomitant AF ablation in patients with AF undergoing CABG or AVR or both does not increase perioperative rates of mortality or morbidity. Moreover, concomitant AF ablation is effective at reducing postoperative AF burden and increases mid-term AF-free survival.
    MeSH term(s) Aged ; Atrial Fibrillation/complications ; Atrial Fibrillation/surgery ; Catheter Ablation/methods ; Coronary Artery Bypass ; Coronary Artery Disease/complications ; Coronary Artery Disease/surgery ; Decision Making ; Female ; Follow-Up Studies ; Heart Valve Diseases/complications ; Heart Valve Diseases/surgery ; Heart Valve Prosthesis Implantation ; Hospital Mortality/trends ; Humans ; Incidence ; Male ; Odds Ratio ; Ontario/epidemiology ; Postoperative Complications/epidemiology ; Retrospective Studies ; Risk Factors ; Treatment Outcome
    Language English
    Publishing date 2017-08
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 211007-6
    ISSN 1552-6259 ; 0003-4975
    ISSN (online) 1552-6259
    ISSN 0003-4975
    DOI 10.1016/j.athoracsur.2016.11.081
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  10. Article ; Online: Aortic root geometry in bicuspid aortic insufficiency versus stenosis: implications for valve repair.

    Al-Atassi, Talal / Hynes, Mark / Sohmer, Benjamin / Lam, Buu-Khanh / Mesana, Thierry / Boodhwani, Munir

    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery

    2014  Volume 47, Issue 4, Page(s) e151–4

    Abstract: Objectives: The contribution of aortic annular and root disease in bicuspid aortic valve (BAV) insufficiency remains unclear. We compared aortic root geometry between BAV stenosis and aortic insufficiency (AI), before and after repair.: Methods: ... ...

    Abstract Objectives: The contribution of aortic annular and root disease in bicuspid aortic valve (BAV) insufficiency remains unclear. We compared aortic root geometry between BAV stenosis and aortic insufficiency (AI), before and after repair.
    Methods: Patients presenting for surgery for BAV insufficiency (n = 58) were compared with patients with BAV stenosis (n = 58). Clinical and transoesophageal echocardiographic data were collected, including end-diastolic diameters of the ventriculo-aortic junction (VAJ), aortic root, sinotubular junction (STJ) and ascending aorta (AA).
    Results: AI patients were younger and more likely to be male compared with aortic stenosis (AS) patients. VAJ, aortic root and STJ diameters were significantly larger in AI compared with AS patients (30 ± 0.5 vs 25 ± 0.4 mm, P < 0.001; 41 ± 0.8 vs 34 ± 0.6 mm, P < 0.001; 36 ± 0.9 vs 30 ± 0.6 mm, P < 0.001, respectively). Following multivariable adjustment for age, sex, body surface area and ascending aortic diameter, these diameters remained larger in AI patients with a mean difference of 3, 6 and 4 mm, respectively (all P < 0.001). Mean AA diameter in the AI group was similar to the AS group (37 ± 1.0 vs 34 ± 0.8 mm, P = 0.06). Forty (69%) AI patients had BAV repair with a mean reduction in VAJ and STJ diameters of 5 and 9 mm compared with prerepair (P < 0.0001).
    Conclusions: Despite the absence of aortic aneurysms, aortic annulus and root dimensions are significantly larger in patients with BAV insufficiency compared with stenosis. Alterations in aortic root geometry contribute to the pathophysiology of BAV insufficiency and require correction for a successful repair.
    MeSH term(s) Aortic Valve/abnormalities ; Aortic Valve/pathology ; Aortic Valve/surgery ; Aortic Valve Insufficiency/epidemiology ; Aortic Valve Insufficiency/pathology ; Aortic Valve Insufficiency/surgery ; Aortic Valve Stenosis/epidemiology ; Aortic Valve Stenosis/pathology ; Aortic Valve Stenosis/surgery ; Bicuspid Aortic Valve Disease ; Female ; Heart Valve Diseases/epidemiology ; Heart Valve Diseases/pathology ; Heart Valve Diseases/surgery ; Humans ; Male ; Middle Aged ; Retrospective Studies
    Language English
    Publishing date 2014-12-30
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 639293-3
    ISSN 1873-734X ; 1010-7940 ; 1567-4258
    ISSN (online) 1873-734X
    ISSN 1010-7940 ; 1567-4258
    DOI 10.1093/ejcts/ezu499
    Database MEDical Literature Analysis and Retrieval System OnLINE

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