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  1. Article ; Online: Comorbidities as mediator or confounder for the association between glycated haemoglobin and postoperative complications: a reply.

    Lam, S

    Anaesthesia

    2022  Volume 77, Issue 10, Page(s) 1178

    MeSH term(s) Blood Glucose ; Comorbidity ; Diabetes Mellitus, Type 2/complications ; Glycated Hemoglobin A/analysis ; Hematologic Tests ; Humans
    Chemical Substances Blood Glucose ; Glycated Hemoglobin A
    Language English
    Publishing date 2022-06-23
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 80033-8
    ISSN 1365-2044 ; 0003-2409
    ISSN (online) 1365-2044
    ISSN 0003-2409
    DOI 10.1111/anae.15791
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 388: Show issues Location:
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  2. Article: American Diabetes Association - 77th Scientific Sessions (June 9-13, 2017 - San Diego, California, USA).

    Lam, S

    Drugs of today (Barcelona, Spain : 1998)

    2017  Volume 53, Issue 7, Page(s) 405–413

    Abstract: The 77th American Diabetes Association (ADA) Sci-entific Sessions took place in San Diego, California. The meeting brought together scientists and professionals from a wide range of disciplines in the field of diabetes and provided a platform for ... ...

    Abstract The 77th American Diabetes Association (ADA) Sci-entific Sessions took place in San Diego, California. The meeting brought together scientists and professionals from a wide range of disciplines in the field of diabetes and provided a platform for networking, allowing experts and researchers to share ideas and learn about the significant advances in diabetes research, treatment and care. Over the course of the 5 days, participants received exclusive access to more than 2,500 original research presentations.
    MeSH term(s) California ; Diabetes Mellitus/drug therapy ; Humans ; United States
    Language English
    Publishing date 2017-07
    Publishing country Spain
    Document type Journal Article ; Review
    ISSN 1699-3993
    ISSN 1699-3993
    DOI 10.1358/dot.2017.53.7.2669148
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: American Diabetes Association - 76th Scientific Sessions (June 10-14, 2016 - New Orleans, Louisiana, USA).

    Lam, S

    Drugs of today (Barcelona, Spain : 1998)

    2016  Volume 52, Issue 6, Page(s) 361–366

    Abstract: The 76th American Diabetes Association (ADA) Scientific Sessions took place in New Orleans, Louisiana, USA. The meeting brought together scientists and professionals from a wide range of disciplines in the field of diabetes and provided a platform for ... ...

    Abstract The 76th American Diabetes Association (ADA) Scientific Sessions took place in New Orleans, Louisiana, USA. The meeting brought together scientists and professionals from a wide range of disciplines in the field of diabetes and provided a platform for networking, allowing experts and researchers to share ideas and learn about the significant advances in diabetes research, treatment and care. Over the course of the 5 days, participants received exclusive access to more than 2,500 original research presentations.
    MeSH term(s) Benzhydryl Compounds/therapeutic use ; Diabetes Mellitus, Type 2/drug therapy ; Glucosides/therapeutic use ; Humans ; Hypoglycemic Agents/therapeutic use ; Phenylpropionates/therapeutic use ; Pyrroles/therapeutic use
    Chemical Substances Benzhydryl Compounds ; Glucosides ; Hypoglycemic Agents ; Phenylpropionates ; Pyrroles ; dapagliflozin (1ULL0QJ8UC) ; saroglitazar (E0YMX3S4JD) ; empagliflozin (HDC1R2M35U)
    Language English
    Publishing date 2016-09-22
    Publishing country Spain
    Document type Congress
    ISSN 1699-3993
    ISSN 1699-3993
    DOI 10.1358/dot.2016.52.6.2516437
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: JAK inhibitors: A broadening approach in rheumatoid arthritis.

    Lam, S

    Drugs of today (Barcelona, Spain : 1998)

    2016  Volume 52, Issue 8, Page(s) 467–469

    Abstract: Pfizer's Xeljanz (tofacitinib citrate) was the first Janus kinase (JAK) inhibitor to reach the market for rheumatoid arthritis (RA) following its U.S. approval in November 2012, and it has since gained approval in more than 45 countries as a second-line ... ...

    Abstract Pfizer's Xeljanz (tofacitinib citrate) was the first Janus kinase (JAK) inhibitor to reach the market for rheumatoid arthritis (RA) following its U.S. approval in November 2012, and it has since gained approval in more than 45 countries as a second-line therapy for RA after failure of disease-modifying antirheumatic drugs (DMARDs). This emerging category has heralded an attractive new class of oral treatment options in RA, with a notable opportunity in patients who stop responding to DMARDs, but they are facing a challenging market. Despite RA affecting approximately 23.7 million people worldwide, Xeljanz faces a market dominated by the anti-tumor necrosis factor (anti-TNF) biologicals, which have robust long-term safety and efficacy. The availability of biosimilars of these market leaders is also intensifying competition, and a high price and uncertainty over long-term safety is currently tempering the market for the JAK inhibitors.
    MeSH term(s) Arthritis, Rheumatoid/drug therapy ; Biosimilar Pharmaceuticals/therapeutic use ; Humans ; Janus Kinase 3/antagonists & inhibitors ; Piperidines/therapeutic use ; Protein Kinase Inhibitors/therapeutic use ; Pyrimidines/therapeutic use ; Pyrroles/therapeutic use
    Chemical Substances Biosimilar Pharmaceuticals ; Piperidines ; Protein Kinase Inhibitors ; Pyrimidines ; Pyrroles ; tofacitinib (87LA6FU830) ; Janus Kinase 3 (EC 2.7.10.2)
    Language English
    Publishing date 2016-08
    Publishing country Spain
    Document type Journal Article
    ISSN 1699-3993
    ISSN 1699-3993
    DOI 10.1358/dot.2016.52.8.2543995
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Audio / Video ; Online: Decades of emerging infectious disease, food safety, and antimicrobial resistance response in Vietnam

    Lam, S. / Hung Nguyen-Viet

    The role of One Health

    2022  

    Keywords emerging diseases ; food safety ; antimicrobial resistance ; one health approach
    Language English
    Publishing date 2022-05-13T12:32:26Z
    Publishing country fr
    Document type Audio / Video ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: How should we secure the cystic duct during laparoscopic cholecystectomy? A UK-wide survey of clinical practice and systematic review of the literature with meta-analysis.

    Arkle, T / Lam, S / Toogood, G / Kumar, B

    Annals of the Royal College of Surgeons of England

    2022  Volume 104, Issue 9, Page(s) 650–654

    Abstract: Introduction: It is currently unknown which method of cystic duct closure is most effective at reducing the risk of bile leak after laparoscopic cholecystectomy. The aims of this work were to determine the most common closure methods used in the UK and ... ...

    Abstract Introduction: It is currently unknown which method of cystic duct closure is most effective at reducing the risk of bile leak after laparoscopic cholecystectomy. The aims of this work were to determine the most common closure methods used in the UK and review available evidence on which method has the lowest risk of bile leak.
    Methods: We conducted an online survey through the Association of Upper Gastrointestinal Surgeons (AUGIS). We also undertook a systematic review using PubMed, EMBASE, MEDLINE and the Cochrane Library for studies that compared different methods for cystic duct occlusion and reported postoperative bile leak.
    Findings: There was significant variation in practice between consultant surgeons. For routine laparoscopic cholecystectomy metal clips were used most (64%) followed by locking polymer clips (33%) and suture ties (3%). In cases of a dilated cystic duct, preferences were locking polymer clips (60%), suture ties (30%) and metal clips (5%). We included six studies in our review with a total of 8,011 patients. Metal clips were associated with an increased odds of bile leak compared with locking polymer clips (OR 5.66, 95% CI 1.13-28.41,
    Conclusions: Limited available evidence suggests that metal clips have the highest risk of bile leak, but results are not strong enough to recommend a change in current clinical practice. A trial is now required to determine the best method of cystic duct closure.
    MeSH term(s) Humans ; Cystic Duct/surgery ; Cholecystectomy, Laparoscopic/adverse effects ; Cholecystectomy, Laparoscopic/methods ; Retrospective Studies ; Polymers ; United Kingdom/epidemiology
    Chemical Substances Polymers
    Language English
    Publishing date 2022-02-23
    Publishing country England
    Document type Systematic Review ; Meta-Analysis ; Journal Article
    ZDB-ID 80044-2
    ISSN 1478-7083 ; 0035-8843
    ISSN (online) 1478-7083
    ISSN 0035-8843
    DOI 10.1308/rcsann.2021.0264
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Uk I Zs.234: Show issues Location:
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  7. Article ; Online: 'Clinical frailty is a risk factor of adverse outcomes in patients with esophageal cancer undergoing esophagectomy: analysis of 2011-2017 US hospitals'.

    Chou, W / Lam, S / Kumar, B

    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    2022  Volume 35, Issue 6

    MeSH term(s) Esophageal Neoplasms/etiology ; Esophageal Neoplasms/surgery ; Esophagectomy/adverse effects ; Frailty/epidemiology ; Frailty/etiology ; Hospitals ; Humans ; Retrospective Studies ; Risk Factors
    Language English
    Publishing date 2022-03-10
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 639470-x
    ISSN 1442-2050 ; 1120-8694
    ISSN (online) 1442-2050
    ISSN 1120-8694
    DOI 10.1093/dote/doac013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2378: Show issues Location:
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  8. Article ; Conference proceedings: Pharmacovigilance Discussion Forum--The European Generic Medicines Association's 8th Annual Meeting (January 21, 2015--London, UK).

    Lam, S

    Drugs of today (Barcelona, Spain : 1998)

    2015  Volume 51, Issue 1, Page(s) 89–92

    Abstract: The practice and science of pharmacovigilance first emerged following the disaster caused by thalidomide in 1961, which led to the initiation of systemic international efforts to address drug safety issues spearheaded by the WHO. Systems were developed ... ...

    Abstract The practice and science of pharmacovigilance first emerged following the disaster caused by thalidomide in 1961, which led to the initiation of systemic international efforts to address drug safety issues spearheaded by the WHO. Systems were developed in member states of the WHO to analyze cases of adverse drug reactions (ADRs) and collate these data into a central database to aid national drug regulatory authorities in improving safety profiles of medicines. Pharmacovigilance is a key public health function for monitoring all medicinal products to assess their quality, efficacy and safety before and following authorization. These medicines are continually assessed to detect any aspect that could compromise their safety, and ensure that the necessary measures are taken. In July 2012, new legislation for pharmacovigilance in the E.U. came into effect as a result of the changes set out in the Directive 2010/84/EU and the European Commission (EC) implementing Regulation (EU) No 520/2012 to reduce the increasing number of ADRs. The latest developments in pharmacovigilance in Europe, including news on E.U. pharmacovigilance legislation, were discussed at the 8th European Generic Medicines Association (EGA) Pharmacovigilance Discussion Forum. The meeting facilitated constructive dialogue between regulators and industry on a range of topics including how to simplify pharmacovigilance activities and improve the processes of risk management plans, periodic safety update reports, signal detection, joint studies and inspections.
    MeSH term(s) Adverse Drug Reaction Reporting Systems ; Cooperative Behavior ; Drug-Related Side Effects and Adverse Reactions/etiology ; Drugs, Generic/adverse effects ; Humans ; International Cooperation ; Pharmacovigilance ; Social Media
    Chemical Substances Drugs, Generic
    Language English
    Publishing date 2015-01
    Publishing country Spain
    Document type Congresses
    ISSN 1699-3993
    ISSN 1699-3993
    DOI 10.1358/dot.2015.51.1.2285587
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Screening for diabetes peri-operatively: a reply.

    Lam, S / Kumar, B / Dhatariya, K

    Anaesthesia

    2022  Volume 77, Issue 10, Page(s) 1180

    Language English
    Publishing date 2022-07-21
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 80033-8
    ISSN 1365-2044 ; 0003-2409
    ISSN (online) 1365-2044
    ISSN 0003-2409
    DOI 10.1111/anae.15805
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Lung Cancer Screening in Never-Smokers.

    Lam, Stephen

    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

    2019  Volume 14, Issue 3, Page(s) 336–337

    MeSH term(s) Early Detection of Cancer ; Humans ; Lung Neoplasms ; Smokers ; Smoking ; Tomography, X-Ray Computed
    Language English
    Publishing date 2019-02-19
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2432037-7
    ISSN 1556-1380 ; 1556-0864
    ISSN (online) 1556-1380
    ISSN 1556-0864
    DOI 10.1016/j.jtho.2018.12.019
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