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Article ; Online: Infection of the hip joint by

Pérusseau-Lambert, Aude / Gouda, Joe Jan / Fareed, Hilal

BMJ case reports

2021 Volume 14, Issue 3

Abstract: A 72-year-old male patient presented to the hospital because of sudden inability to bear weight and without a history of trauma. A fracture of the head of the femur was identified on CT scan of the pelvis. In his history, the patient had a hospital ... ...

Abstract	A 72-year-old male patient presented to the hospital because of sudden inability to bear weight and without a history of trauma. A fracture of the head of the femur was identified on CT scan of the pelvis. In his history, the patient had a hospital admission 3 months earlier, during which he had a urinary catheter, and a urine specimen was analysed. The same pathogen was found in the patient urine and in the head of the femur specimen. This is a report of blood-borne spread of
MeSH term(s)	Aged ; Femur Head ; Fractures, Bone ; Hip Joint ; Humans ; Male ; Serratia Infections/diagnosis ; Serratia marcescens
Language	English
Publishing date	2021-03-17
Publishing country	England
Document type	Case Reports ; Journal Article
ISSN	1757-790X
ISSN (online)	1757-790X
DOI	10.1136/bcr-2020-234607
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Article ; Online: Psoriasis risk after beta-blocker exposure: Description of a pharmacovigilance signal.

Azzouz, Brahim / De Guizelin, Apolline / Lambert, Aude / Fresse, Audrey / Morel, Aurore / Trenque, Thierry

British journal of clinical pharmacology

2022 Volume 88, Issue 8, Page(s) 3813–3818

Abstract: Aim: We aimed to investigate French pharmacovigilance data. The objective was to characterize psoriatic conditions that occurred after beta-blocker (BB) exposure and bring to light a possible pharmacovigilance signal.: Methods: Spontaneous reports of ...

Abstract	Aim: We aimed to investigate French pharmacovigilance data. The objective was to characterize psoriatic conditions that occurred after beta-blocker (BB) exposure and bring to light a possible pharmacovigilance signal. Methods: Spontaneous reports of psoriatic conditions recorded in the French National Pharmacovigilance Database (FPVD) between 1985 and 2019 were extracted. We performed a retrospective, descriptive analysis of reports linked to BB exposure. Association between psoriasis risk and BB exposure was assessed using a case/noncase study. Results: Two hundred and twenty-five reports of psoriatic conditions after BB exposure were recorded in the FPVD during the study period. Both cardioselective and noncardioselective, topical and systemic BBs are involved. Therapeutic indication of BB was mainly hypertension. Mean time to onset was 5 months and outcome was favourable in 68% after BB discontinuation. These features were concordant with those of literature reports. The reporting odds ratio (ROR) was 8.95 (95% confidence interval 7.75-10.33). Conclusion: We highlighted a statistically significant disproportionality which constitutes a pharmacovigilance signal. Psoriasis risk with BBs is a class effect. Increasing surveillance during the first year of BB exposure is needed.
MeSH term(s)	Adrenergic beta-Antagonists/adverse effects ; Adverse Drug Reaction Reporting Systems ; Databases, Factual ; Humans ; Pharmacovigilance ; Psoriasis/chemically induced ; Psoriasis/drug therapy ; Psoriasis/epidemiology ; Retrospective Studies
Chemical Substances	Adrenergic beta-Antagonists
Language	English
Publishing date	2022-04-06
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	188974-6
ISSN	1365-2125 ; 0306-5251 ; 0264-3774
ISSN (online)	1365-2125
ISSN	0306-5251 ; 0264-3774
DOI	10.1111/bcp.15330
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Zs.A 1118: Show issues

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Article ; Online: Targeted chemodenervation of the posterior belly of the digastric muscle for the management of jaw discomfort in facial synkinesis.

Pescarini, Elena / Butler, Daniel P / Perusseau-Lambert, Aude / Nduka, Charles / Kannan, Ruben Y

Journal of plastic, reconstructive & aesthetic surgery : JPRAS

2021 Volume 74, Issue 12, Page(s) 3437–3442

Abstract: Background: Botulinum toxin (BT-A) chemodenervation has been proved to significantly improve the physical and psychological well-being of patients suffering from facial synkinesis. Despite this, a cohort of patients has persistent tightness and ... ...

Abstract	Background: Botulinum toxin (BT-A) chemodenervation has been proved to significantly improve the physical and psychological well-being of patients suffering from facial synkinesis. Despite this, a cohort of patients has persistent tightness and discomfort around the angle of the jaw, which may be caused by synkinesis within the posterior belly of digastric (PBD) muscle. This study was designed to evaluate the benefits of ultrasound-guided BT-A injections into the PBD. Methods: Thirty-three patients with recalcitrant tightness and discomfort around the angle of the jaw, despite maximal facial therapy and platysmal chemodenervation were selected for inclusion. Patients underwent ultrasound-guided BT-A injection into the ipsilateral PBD muscle (skin puncture site 1 cm inferior and posterior to the angle of mandible). Outcomes consisted of the Facial Disability Index (FDI), Synkinesis Assessment Questionnaire (SAQ), and a visual analogue scale (VAS) designed to assess tightness and pain around the PBD when moving the jaw, swallowing, and masticating. Questionnaires were completed two weeks before and postinjection. Statistical analysis was performed using a paired t-test. Results: Nineteen patients completed the post-treatment outcome questionnaire. A statistically significant improvement was noted in the physical and social function aspects of the FDI and all aspects of the patient-reported VAS scores apart from tightness and pain on jaw retrusion and swallowing. There was no significant difference in the SAQ. Conclusion: This study has demonstrated the patient-perceived benefit of ultrasound-targeted BT-A chemodenervation of PBD. This represents a low-risk treatment option that can be easily added to the repertoire of treatments offered to patients with post paralysis facial synkinesis.
MeSH term(s)	Adult ; Aged ; Botulinum Toxins, Type A/therapeutic use ; Disability Evaluation ; Facial Muscles/drug effects ; Facial Muscles/innervation ; Female ; Humans ; Injections, Intramuscular ; Male ; Middle Aged ; Neuromuscular Agents/therapeutic use ; Pain Measurement ; Surveys and Questionnaires ; Synkinesis/drug therapy ; Ultrasonography, Interventional
Chemical Substances	Neuromuscular Agents ; Botulinum Toxins, Type A (EC 3.4.24.69)
Language	English
Publishing date	2021-06-09
Publishing country	Netherlands
Document type	Journal Article ; Video-Audio Media
ZDB-ID	2217750-4
ISSN	1878-0539 ; 1748-6815 ; 0007-1226
ISSN (online)	1878-0539
ISSN	1748-6815 ; 0007-1226
DOI	10.1016/j.bjps.2021.05.045
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Article ; Online: Adverse drug reactions in pregnant women: Do they differ from those in non-pregnant women of childbearing age?

Balon, Maylis / Tessier, Samuel / Damase-Michel, Christine / Cottin, Judith / Lambert, Aude / Thompson, Marie-Andrée / Benevent, Justine / Lacroix, Isabelle

Therapie

2022 Volume 78, Issue 2, Page(s) 165–173

Abstract: Pharmacoepidemiological research in pregnant women has focused on adverse drug reactions for the course of pregnancy or for the unborn child, but little is known on the risks for the mother. We reported the results of a study that compared adverse drug ... ...

Abstract	Pharmacoepidemiological research in pregnant women has focused on adverse drug reactions for the course of pregnancy or for the unborn child, but little is known on the risks for the mother. We reported the results of a study that compared adverse drug reactions in pregnant women with non-pregnant women of childbearing age, and investigated whether which types of adverse reactions were more often reported in pregnant women and which drugs were more often involved. This study was carried out in the French pharmacovigilance database (BNPV). We compared adverse drug reactions reported between 1 January 2010 and 31 December 2019 in pregnant women with those reported in of non-pregnant women of childbearing age. We cross-matched each pregnant woman with three non-pregnant women of childbearing age according to geographic area, age and year the adverse reaction was reported. Data analysis revealed that serious adverse reactions were more frequently reported in pregnant women, including anaphylactic reactions. Other adverse reactions including tachycardia, hypotension and hepatic injury were also more frequent in pregnant women than in non-pregnant women of the same age. This could be explained by physiological changes in pregnancy that lead to greater sensitivity to certain adverse reactions. Some drugs, such as phloroglucinol, metoclopramide, iron, atosiban and nifedipine, were more frequently involved in adverse reactions in pregnant women. These drugs are specifically used during pregnancy, which may explain why they are over-represented in adverse reactions. This is the first comparative descriptive study on drug adverse reactions in pregnant women. Specific epidemiological and pharmacokinetic studies are necessary to confirm these results and better understand the differences observed to improve the monitoring of pregnant women exposed to certain drugs.
MeSH term(s)	Pregnancy ; Humans ; Female ; Pregnant Women ; Drug-Related Side Effects and Adverse Reactions/epidemiology ; Pharmacovigilance
Language	English
Publishing date	2022-11-28
Publishing country	France
Document type	Journal Article
ZDB-ID	603474-3
ISSN	1958-5578 ; 0040-5957
ISSN (online)	1958-5578
ISSN	0040-5957
DOI	10.1016/j.therap.2022.11.005
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Article ; Online: Safety Signal Generation for Sudden Sensorineural Hearing Loss Following Messenger RNA COVID-19 Vaccination: Postmarketing Surveillance Using the French Pharmacovigilance Spontaneous Reporting Database.

Thai-Van, Hung / Valnet-Rabier, Marie-Blanche / Anciaux, Maëva / Lambert, Aude / Maurier, Anaïs / Cottin, Judith / Pietri, Tessa / Destère, Alexandre / Damin-Pernik, Marlène / Perrouin, Fanny / Bagheri, Haleh

JMIR public health and surveillance

2023 Volume 9, Page(s) e45263

Abstract: Background: The World Health Organization recently described sudden sensorineural hearing loss (SSNHL) as a possible adverse effect of COVID-19 vaccines. Recent discordant pharmacoepidemiologic studies invite robust clinical investigations of SSNHL ... ...

Abstract	Background: The World Health Organization recently described sudden sensorineural hearing loss (SSNHL) as a possible adverse effect of COVID-19 vaccines. Recent discordant pharmacoepidemiologic studies invite robust clinical investigations of SSNHL after COVID-19 messenger RNA (mRNA) vaccines. This postmarketing surveillance study, overseen by French public health authorities, is the first to clinically document postvaccination SSNHL and examine the role of potential risk factors. Objective: This nationwide study aimed to assess the relationship between SSNHL and exposure to mRNA COVID-19 vaccines and estimate the reporting rate (Rr) of SSNHL after mRNA vaccination per 1 million doses (primary outcome). Methods: We performed a retrospective review of all suspected cases of SSNHL after mRNA COVID-19 vaccination spontaneously reported in France between January 2021 and February 2022 based on a comprehensive medical evaluation, including the evaluation of patient medical history, side and range of hearing loss, and hearing recovery outcomes after a minimum period of 3 months. The quantification of hearing loss and assessment of hearing recovery outcomes were performed according to a grading system modified from the Siegel criteria. A cutoff of 21 days was used for the delay onset of SSNHL. The primary outcome was estimated using the total number of doses of each vaccine administered during the study period in France as the denominator. Results: From 400 extracted cases for tozinameran and elasomeran, 345 (86.3%) spontaneous reports were selected. After reviewing complementary data, 49.6% (171/345) of documented cases of SSNHL were identified. Of these, 83% (142/171) of SSNHL cases occurred after tozinameran vaccination: Rr=1.45/1,000,000 injections; no difference for the rank of injections; complete recovery in 22.5% (32/142) of cases; median delay onset before day 21=4 days (median age 51, IQR 13-83 years); and no effects of sex. A total of 16.9% (29/171) of SSNHL cases occurred after elasomeran vaccination: Rr=1.67/1,000,000 injections; rank effect in favor of the first injection (P=.03); complete recovery in 24% (7/29) of cases; median delay onset before day 21=8 days (median age 47, IQR 33-81 years); and no effects of sex. Autoimmune, cardiovascular, or audiovestibular risk factors were present in approximately 29.8% (51/171) of the cases. SSNHL was more often unilateral than bilateral for both mRNA vaccines (P<.001 for tozinameran; P<.003 for elasomeran). There were 13.5% (23/142) of cases of profound hearing loss, among which 74% (17/23) did not recover a serviceable ear. A positive rechallenge was documented for 8 cases. Conclusions: SSNHL after COVID-19 mRNA vaccines are very rare adverse events that do not call into question the benefits of mRNA vaccines but deserve to be known given the potentially disabling impact of sudden deafness. Therefore, it is essential to properly characterize postinjection SSNHL, especially in the case of a positive rechallenge, to provide appropriate individualized recommendations.
MeSH term(s)	Humans ; Middle Aged ; 2019-nCoV Vaccine mRNA-1273 ; BNT162 Vaccine ; COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19/complications ; COVID-19 Vaccines/adverse effects ; Hearing Loss, Sensorineural/complications ; Hearing Loss, Sudden/etiology ; Pharmacovigilance ; Vaccination/adverse effects
Chemical Substances	2019-nCoV Vaccine mRNA-1273 (EPK39PL4R4) ; BNT162 Vaccine ; COVID-19 Vaccines
Language	English
Publishing date	2023-07-14
Publishing country	Canada
Document type	Journal Article
ISSN	2369-2960
ISSN (online)	2369-2960
DOI	10.2196/45263
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Article ; Online: Laboratory diagnosis of heparin-induced thrombocytopenia: A retrospective experience.

Herb, Agathe / Depierreux, Mathilde / Wimmer, Jordan / Rolland, Delphine / Tebacher, Martine / Lambert, Aude / Ladhari, Chayma / Cristinar, Mircea / Delabranche, Xavier / Krummel, Thierry / Paya, Dominique / Schenck, Maleka / Mauvieux, Laurent / Sattler, Laurent

Journal of clinical laboratory analysis

2023 Volume 37, Issue 7, Page(s) e24884

Abstract: Background: Heparin-induced thrombocytopenia (HIT) is a severe complication of heparin therapy associated with thrombosis that requires a quick diagnosis. Therefore, laboratory assays must provide an accurate and swift answer. This work aims to evaluate ...

Abstract	Background: Heparin-induced thrombocytopenia (HIT) is a severe complication of heparin therapy associated with thrombosis that requires a quick diagnosis. Therefore, laboratory assays must provide an accurate and swift answer. This work aims to evaluate the performances of an ELISA assay, especially when combined with 4T risk score, and a functional assay. Methods: Data were collected for 894 patients treated by heparin who underwent anticoagulant switch because of HIT suspicion and were examined by a multidisciplinary expert team who confirmed or ruled out HIT diagnosis. All patients were tested for anti-PF4 IgG with Asserachrom HPIA IgG (ELISA), and 307 were tested with a platelet aggregation test done on platelet-rich plasma (PRP-PAT). The 4T risk score was available for 607 of them. Results: HIT was diagnosed in 232 patients. 4T risk score had a 94.2% negative predictive value (NPV) for risk scores ≤3 and 77.3% for risk scores ≤5. The sensitivity of ELISA was 90.9%, its specificity 79.0%, and its NPV 96.1%. When combined with 4T risk score, its NPV reached 100% and 97% for risk scores ≤3 and ≤5, respectively. PRP-PAT sensitivity was 70.4%, and its specificity was 92.3%. Combination of ELISA and PRP-PAT had a 0.7% false-negative rate. Conclusion: This study shows that ELISA can rule out HIT with an excellent NPV, especially when combined with the 4T risk score. Nonetheless, it has low specificity; hence, it needs to be associated with a functional assay.
MeSH term(s)	Humans ; Retrospective Studies ; Platelet Factor 4/adverse effects ; Thrombocytopenia/chemically induced ; Thrombocytopenia/diagnosis ; Heparin/adverse effects ; Anticoagulants/adverse effects ; Enzyme-Linked Immunosorbent Assay ; Platelet Function Tests ; Immunoglobulin G
Chemical Substances	Platelet Factor 4 (37270-94-3) ; Heparin (9005-49-6) ; Anticoagulants ; Immunoglobulin G
Language	English
Publishing date	2023-04-23
Publishing country	United States
Document type	Journal Article
ZDB-ID	645095-7
ISSN	1098-2825 ; 0887-8013
ISSN (online)	1098-2825
ISSN	0887-8013
DOI	10.1002/jcla.24884
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Article ; Online: N-Acetyl Cysteine Restores Limb Function, Improves Mitochondrial Respiration, and Reduces Oxidative Stress in a Murine Model of Critical Limb Ischaemia.

Lejay, Anne / Paradis, Stéphanie / Lambert, Aude / Charles, Anne-Laure / Talha, Samy / Enache, Irina / Thaveau, Fabien / Chakfe, Nabil / Geny, Bernard

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery

2018 Volume 56, Issue 5, Page(s) 730–738

Abstract: Objective/background: The aim of this study was to investigate whether antioxidant therapy might decrease oxidative stress related deleterious effects in the setting of critical limb ischaemia (CLI).: Methods: Twenty Swiss mice were submitted to ... ...

Abstract	Objective/background: The aim of this study was to investigate whether antioxidant therapy might decrease oxidative stress related deleterious effects in the setting of critical limb ischaemia (CLI). Methods: Twenty Swiss mice were submitted to sequential right femoral and iliac ligatures; the left limb served as control. The mice were assigned to two groups: in the first group (no-treatment group, n = 10) no treatment was administered; in the second group (N-acetyl cysteine [NAC] group, n = 10) NAC was administered by dissolution in drinking water for 4 weeks, starting on day 7, when CLI was effective. Clinical and functional scores were assessed by two blinded investigators. Mice were killed on day 40 and mitochondrial respiratory chain complex activities, calcium retention capacity, oxidative stress, and histological analysis were analysed. Results: Ischaemic muscles in the no-treatment group showed significantly impaired mitochondrial respiration and calcium retention capacity, with increased production of reactive oxygen species; but no statistical difference was noticed when comparing ischaemic muscles in the NAC group (n = 10) to contralateral muscles (n = 10) and to control muscles in the no-treatment group (n = 10). Ischaemic muscles in the no-treatment group exhibited myopathic features such as wider range in fibre size, rounded shape, centrally located nuclei, and smaller cross sectional areas, but none of these features were observed in contralateral muscles or in NAC-group muscles (ischaemic or controls). Conclusion: Targeting inhibition of oxidative stress may be a potential therapeutic strategy for muscle protection in CLI and might be considered as potential adjunctive therapy to revascularisation procedures.
MeSH term(s)	Acetylcysteine/therapeutic use ; Animals ; Calcium/metabolism ; Ischemia/drug therapy ; Ischemia/metabolism ; Male ; Mice ; Mitochondria/drug effects ; Muscle, Skeletal/blood supply ; Oxidative Stress/drug effects ; Reactive Oxygen Species/metabolism
Chemical Substances	Reactive Oxygen Species ; Calcium (SY7Q814VUP) ; Acetylcysteine (WYQ7N0BPYC)
Language	English
Publishing date	2018-08-29
Publishing country	England
Document type	Journal Article
ZDB-ID	1225869-6
ISSN	1532-2165 ; 1078-5884
ISSN (online)	1532-2165
ISSN	1078-5884
DOI	10.1016/j.ejvs.2018.07.025
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Zs.A 2283: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Immediate-Type Hypersensitivity Cross-Reactions to Proton Pump Inhibitors: A Descriptive Study of Data from the French National Pharmacovigilance Database.

Tourillon, Caroline / Mahe, Julien / Baron, Aurélie / Lambert, Aude / Yélehé-Okouma, Mélissa / Veyrac, Gwenaelle / Jolliet, Pascale

International archives of allergy and immunology

2018 Volume 178, Issue 2, Page(s) 159–166

Abstract: Background: Proton pump inhibitors (PPIs) can trigger immediate-type hypersensitivity reactions (HSRs). Three main patterns of cross-reactivity have been identified: reactions to a single PPI, selective cross-reactions, and cross-reactions with all PPIs. ...

Abstract	Background: Proton pump inhibitors (PPIs) can trigger immediate-type hypersensitivity reactions (HSRs). Three main patterns of cross-reactivity have been identified: reactions to a single PPI, selective cross-reactions, and cross-reactions with all PPIs. Several hypotheses have been advanced, but no consensus has been reached. Objective: We sought to identify immediate-type hypersensitivity cross-reactions to PPIs using real-world data about hypersensitivity testing from French pharmacovigilance cases. Methods: Potentially relevant immediate-type HSRs reported from January 1985 to February 2015 were extracted from the French pharmacovigilance database using a standardized MedDRA query (SMQ). Cases describing skin tests or oral provocation tests (OPTs) performed with several PPIs that yielded at least one positive result were included. Results: The SMQ extracted 2,119 cases, 38 of which were included in our study. Data collected from skin tests and OPTs indicated cross-reactions with all PPIs (n = 1), reactions to a single PPI (n = 14), or selective cross-reactions (n = 23). Esomeprazole, omeprazole, and pantoprazole concerned 78% of all selective cross-reactions. In more than half of the cases (55.3%), only 2 PPIs were tested. Conclusion: To the best of our knowledge, this PPI cross-reactivity study is the largest to date in terms of population size, describing 38 immediate-type HSRs to PPIs explored by skin tests or OPTs. This paucity of data belies the lack of standardized procedures for PPI hypersensitivity testing. It is likely that PPI HSR workups in everyday clinical practice are often incomplete. Further research to gain insight into selective cross-reactions between PPIs is needed. In the meantime, thorough workups should be completed when a PPI is suspected to have triggered an HSR, instead of routine contraindication to all PPIs.
MeSH term(s)	Adult ; Aged ; Cross Reactions/immunology ; Drug Hypersensitivity/epidemiology ; Drug Hypersensitivity/immunology ; Female ; France/epidemiology ; Humans ; Hypersensitivity, Immediate/epidemiology ; Hypersensitivity, Immediate/immunology ; Male ; Middle Aged ; Pharmacovigilance ; Proton Pump Inhibitors/adverse effects ; Retrospective Studies
Chemical Substances	Proton Pump Inhibitors
Language	English
Publishing date	2018-11-28
Publishing country	Switzerland
Document type	Systematic Review
ZDB-ID	1108932-5
ISSN	1423-0097 ; 1018-2438
ISSN (online)	1423-0097
ISSN	1018-2438
DOI	10.1159/000493581
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Article ; Online: Treatment with flow diverter stent during pregnancy.

Pop, Raoul / Cebula, Helene / Lambert, Aude / Mihoc, Dan / Manisor, Monica / Cindea, Cosmin / Hasiu, Anca / Deruelle, Philippe / Chibbaro, Salvatore / Mertz, Luc / Proust, Francois / Beaujeux, Remy

Neuroradiology

2020 Volume 62, Issue 11, Page(s) 1507–1510

Abstract: Intracranial aneurysms are rarely diagnosed during pregnancy. If treatment is necessary, surgery was traditionally preferred over embolization in case of ongoing pregnancy, due to concerns regarding foetal radiation exposure. We present a case of 21 mm ... ...

Abstract	Intracranial aneurysms are rarely diagnosed during pregnancy. If treatment is necessary, surgery was traditionally preferred over embolization in case of ongoing pregnancy, due to concerns regarding foetal radiation exposure. We present a case of 21 mm unruptured carotid-ophthalmic aneurysm diagnosed during pregnancy and treated with flow diversion. Foetal radiation dose was estimated between 1 and 5 mGy, well below recommended limits. Double antiplatelet therapy with prasugrel and aspirin was administered between week 17 and week 37, followed by uneventful vaginal delivery at 39 weeks. The new-born infant did not present any clinical abnormalities. Post-natal angiography showed complete aneurysm occlusion. To our knowledge, this is the first report of flow diverter stent placement during ongoing pregnancy. Although a good outcome was observed in this case, this result should be interpreted with caution. Further studies are needed in order to better define the safety profiles of intracranial stents and double antiplatelet therapies during pregnancy.
MeSH term(s)	Adult ; Angiography, Digital Subtraction ; Cerebral Angiography ; Embolization, Therapeutic/methods ; Female ; Humans ; Intracranial Aneurysm/diagnostic imaging ; Intracranial Aneurysm/therapy ; Magnetic Resonance Angiography ; Platelet Aggregation Inhibitors/therapeutic use ; Pregnancy ; Pregnancy Complications, Cardiovascular/diagnostic imaging ; Pregnancy Complications, Cardiovascular/therapy ; Pregnancy Outcome ; Stents
Chemical Substances	Platelet Aggregation Inhibitors
Language	English
Publishing date	2020-06-22
Publishing country	Germany
Document type	Case Reports ; Journal Article
ZDB-ID	123305-1
ISSN	1432-1920 ; 0028-3940
ISSN (online)	1432-1920
ISSN	0028-3940
DOI	10.1007/s00234-020-02474-0
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Article ; Online: Rivaroxaban-induced liver injury: Results from a venous thromboembolism registry.

Lambert, Aude / Cordeanu, Mihaela / Gaertner, Sébastien / Nouri, Salah / Alt, Martine / Stephan, Dominique

International journal of cardiology

2015 Volume 191, Page(s) 265–266

MeSH term(s)	Adult ; Aged ; Chemical and Drug Induced Liver Injury/diagnosis ; Chemical and Drug Induced Liver Injury/epidemiology ; Factor Xa Inhibitors/adverse effects ; Female ; Humans ; Male ; Middle Aged ; Prospective Studies ; Registries ; Rivaroxaban/adverse effects ; Venous Thromboembolism/diagnosis ; Venous Thromboembolism/drug therapy ; Venous Thromboembolism/epidemiology
Chemical Substances	Factor Xa Inhibitors ; Rivaroxaban (9NDF7JZ4M3)
Language	English
Publishing date	2015-07-15
Publishing country	Netherlands
Document type	Letter ; Observational Study
ZDB-ID	779519-1
ISSN	1874-1754 ; 0167-5273
ISSN (online)	1874-1754
ISSN	0167-5273
DOI	10.1016/j.ijcard.2015.04.248
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In stock of ZB MED Cologne/Königswinter

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In stock of ZB MED Cologne/Königswinter

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In stock of ZB MED Cologne/Königswinter

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In stock of ZB MED Cologne/Königswinter

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