Article ; Online: A Role for SMARCB1 in Synovial Sarcomagenesis Reveals That SS18-SSX Induces Canonical BAF Destruction.
2021 Volume 11, Issue 10, Page(s) 2620–2637
Abstract: Reduced protein levels of SMARCB1 (also known as BAF47, INI1, SNF5) have long been observed in synovial sarcoma. Here, we show that ... ...
| Abstract | Reduced protein levels of SMARCB1 (also known as BAF47, INI1, SNF5) have long been observed in synovial sarcoma. Here, we show that combined |
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| MeSH term(s) | Animals ; Cell Line, Tumor ; Cell Transformation, Neoplastic ; Disease Models, Animal ; Female ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Oncogene Proteins, Fusion/genetics ; SMARCB1 Protein/genetics ; Sarcoma, Synovial/genetics ; Sarcoma, Synovial/pathology | |||||
| Chemical Substances | Oncogene Proteins, Fusion ; SMARCB1 Protein ; SMARCB1 protein, human ; SS18-SSX1 fusion protein | |||||
| Language | English | |||||
| Publishing date | 2021-06-02 | |||||
| Publishing country | United States | |||||
| Document type | Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't | |||||
| ZDB-ID | 2625242-9 | |||||
| ISSN | 2159-8290 ; 2159-8274 | |||||
| ISSN (online) | 2159-8290 | |||||
| ISSN | 2159-8274 | |||||
| DOI | 10.1158/2159-8290.CD-20-1219 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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