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  1. Book: Case based diagnosis and management of headache disorders

    Siva, Aksel / Lampl, Christian

    (Headache)

    2014  

    Title variant Case-based diagnosis and management of headache disorders
    Author's details Aksel Siva ; Christian Lampl ed
    Series title Headache
    Keywords Headache/Diagnosis ; Headache/Treatment
    Subject code 616.8491
    Language English
    Size XI, 281 S. : Ill., graph. Darst., 24 cm
    Publisher Springer
    Publishing place Cham u.a.
    Publishing country Switzerland
    Document type Book
    Note Includes bibliographical references
    HBZ-ID HT018412614
    ISBN 978-3-319-06885-5 ; 9783319068862 ; 3-319-06885-7 ; 3319068865
    Database Catalogue ZB MED Medicine, Health

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  2. Book: Moderne angewandte Migränetherapie

    Lampl, Christian

    (Uni-Med-Science)

    2007  

    Author's details [Christian Lampl (Hrsg.)]
    Series title Uni-Med-Science
    Keywords Migräne ; Pharmakotherapie
    Subject Arzneimitteltherapie ; Arzneitherapie ; Medikamentöse Therapie ; Hemikranie
    Language German
    Size 77 S. : Ill., graph. Darst.
    Edition 1. Aufl.
    Publisher Uni-Med-Verl
    Publishing place Bremen u.a.
    Publishing country Germany
    Document type Book
    HBZ-ID HT014982573
    ISBN 978-3-89599-920-8 ; 3-89599-920-2
    Database Catalogue ZB MED Medicine, Health

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  3. Article: EHF: "Es braucht internationale Zusammenarbeit", Präsident Christian Lampl im Interview

    Lampl, Christian

    Neurologisch

    2021  Volume -, Issue 4, Page(s) 13

    Language German
    Document type Article
    ZDB-ID 2475252-6
    ISSN 2223-0629
    Database Current Contents Medicine

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  4. Article ; Online: Narrative-based medicine in headache disorders.

    Lampl, Christian / Sacco, Simona / Martelletti, Paolo

    The journal of headache and pain

    2022  Volume 23, Issue 1, Page(s) 66

    Abstract: In this editorial we aim to provide an overview of Narrative-based Medicine (NBM) and highlight what it may offer to the care of individuals with headache disorders. ...

    Abstract In this editorial we aim to provide an overview of Narrative-based Medicine (NBM) and highlight what it may offer to the care of individuals with headache disorders.
    MeSH term(s) Headache Disorders/therapy ; Humans
    Language English
    Publishing date 2022-06-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 2036768-5
    ISSN 1129-2377 ; 1129-2369
    ISSN (online) 1129-2377
    ISSN 1129-2369
    DOI 10.1186/s10194-022-01437-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: New Migraine Drugs for Older Adults.

    Onan, Dilara / Wells-Gatnik, William David / Bentivegna, Enrico / Lampl, Christian / Martelletti, Paolo

    Drugs & aging

    2023  Volume 40, Issue 4, Page(s) 301–305

    Abstract: Migraine is one of the most widespread and burdensome diseases, affecting one in every seven individuals in the world, for an estimated global prevalence of 14%. Until recently, therapeutic choices for older migraineurs have been limited by safety ... ...

    Abstract Migraine is one of the most widespread and burdensome diseases, affecting one in every seven individuals in the world, for an estimated global prevalence of 14%. Until recently, therapeutic choices for older migraineurs have been limited by safety concerns and such patients have typically been excluded from clinical trials. However, randomized controlled trials (RCTs) of new migraine drugs have begun to include participants aged over 65 years, offering clinicians relevant safety and efficacy data to be able to treat older patients with the newest drug classes, including monoclonal antibodies for CGRP (r), CGRP antagonists, and drugs targeting the serotonin 5-HT
    MeSH term(s) Humans ; Aged ; Calcitonin Gene-Related Peptide/therapeutic use ; Migraine Disorders/drug therapy ; Antibodies, Monoclonal/therapeutic use
    Chemical Substances Calcitonin Gene-Related Peptide (JHB2QIZ69Z) ; Antibodies, Monoclonal
    Language English
    Publishing date 2023-02-24
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 1075770-3
    ISSN 1179-1969 ; 1170-229X
    ISSN (online) 1179-1969
    ISSN 1170-229X
    DOI 10.1007/s40266-023-01012-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Two early descriptions of restless legs syndrome by J. Astruc (1736) and M.A. Weikard (1796).

    Langebner, Thomas / Lampl, Christian

    Neurology

    2018  Volume 91, Issue 17, Page(s) 786–789

    Abstract: Objective: To find and analyze early descriptions of restless legs syndrome (RLS).: Methods: Databases and textbooks were searched to document the current knowledge on the history of RLS and to identify additional early descriptions of RLS.: ... ...

    Abstract Objective: To find and analyze early descriptions of restless legs syndrome (RLS).
    Methods: Databases and textbooks were searched to document the current knowledge on the history of RLS and to identify additional early descriptions of RLS.
    Results: Two recently discovered early descriptions of RLS are presented together with a review of the current knowledge on the history of RLS.
    Conclusions: The French physician Jean Astruc described an RLS-like condition in 1736. In his
    MeSH term(s) Databases, Factual/statistics & numerical data ; History, 17th Century ; History, 18th Century ; Humans ; Physicians/history ; Restless Legs Syndrome/diagnosis ; Restless Legs Syndrome/history
    Language English
    Publishing date 2018-10-23
    Publishing country United States
    Document type Historical Article ; Journal Article
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0000000000006393
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book: Case-based diagnosis and management of headache disorders

    Siva, Aksel / Lampl, Christian

    (Headache)

    2015  

    Author's details Aksel Siva, Christian Lampl, editors
    Series title Headache
    MeSH term(s) Headache Disorders/diagnosis ; Headache Disorders/therapy ; Migraine Disorders/diagnosis ; Migraine Disorders/therapy ; Diagnosis, Differential
    Language English
    Size xi, 281 pages :, illustrations (partly color) ;, 25 cm.
    Document type Book
    ISBN 9783319068855 ; 3319068857 ; 9783319068862 ; 3319068865
    Database Catalogue of the US National Library of Medicine (NLM)

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  8. Article: Migräne - Klinik, Diagnostik, Therapie und Prophylaxe.

    Lampl, Christian

    Therapeutische Umschau. Revue therapeutique

    2011  Volume 68, Issue 9, Page(s) 501–505

    Abstract: Migraine is a chronic. disabling, biologically determined, inherited brain disorder rendering life much less tolerable. The International Headache Society (IHS) offers guidelines for the classification and diagnosis of migraine headaches, in a document ... ...

    Title translation Migraine - diagnostic features, acute therapy and prophylactics.
    Abstract Migraine is a chronic. disabling, biologically determined, inherited brain disorder rendering life much less tolerable. The International Headache Society (IHS) offers guidelines for the classification and diagnosis of migraine headaches, in a document called 'The International Classification of Headache Disorders, 2nd edition' (ICHD-2). Migraine affects 10-16% of the population world-wide. For the 20-30% of migraine sufferers who experience migraine with aura, this aura comprises focal neurological phenomena that precede or accompany the attack. There are three main aspects of treatment: trigger avoidance, acute symptomatic control, and pharmacological prevention. Acute medications are more effective if used earlier in an attack. The goals of preventive therapy are to reduce the frequency, painfulness, and/or duration of migraines, and to increase quality of life.
    MeSH term(s) Analgesics/adverse effects ; Analgesics/therapeutic use ; Anti-Inflammatory Agents, Non-Steroidal/adverse effects ; Anti-Inflammatory Agents, Non-Steroidal/therapeutic use ; Antiemetics/adverse effects ; Antiemetics/therapeutic use ; Cross-Sectional Studies ; Dose-Response Relationship, Drug ; Drug Administration Schedule ; Ergot Alkaloids/adverse effects ; Ergot Alkaloids/therapeutic use ; Humans ; Migraine Disorders/diagnosis ; Migraine Disorders/drug therapy ; Migraine Disorders/epidemiology ; Migraine Disorders/etiology ; Migraine with Aura/diagnosis ; Migraine with Aura/epidemiology ; Migraine with Aura/etiology ; Migraine with Aura/therapy ; Risk Factors ; Secondary Prevention ; Tryptamines/adverse effects ; Tryptamines/therapeutic use
    Chemical Substances Analgesics ; Anti-Inflammatory Agents, Non-Steroidal ; Antiemetics ; Ergot Alkaloids ; Tryptamines
    Language German
    Publishing date 2011-09
    Publishing country Switzerland
    Document type English Abstract ; Journal Article ; Review
    ZDB-ID 82044-1
    ISSN 1664-2864 ; 0040-5930
    ISSN (online) 1664-2864
    ISSN 0040-5930
    DOI 10.1024/0040-5930/a000202
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: The increasing role of electronic media in headache.

    Do, Thien Phu / Andreou, Anna P / de Oliveira, Arao Belitardo / Shapiro, Robert E / Lampl, Christian / Amin, Faisal Mohammad

    BMC neurology

    2023  Volume 23, Issue 1, Page(s) 194

    Abstract: Most individuals with access to the internet use social media platforms. These platforms represent an excellent opportunity to disseminate knowledge about management and treatment to the benefit of patients. The International Headache Society, The ... ...

    Abstract Most individuals with access to the internet use social media platforms. These platforms represent an excellent opportunity to disseminate knowledge about management and treatment to the benefit of patients. The International Headache Society, The European Headache Federation, and The American Headache Society have electronic media committees to promote and highlight the organizations' expertise and disseminate research findings. A growing mistrust in science has made dealing with infodemics (i.e., sudden access to excessive unvetted information) an increasing part of clinical management. An increasing role of these committees will be to address this challenge. As an example, recent studies have demonstrated that the most popular online content on migraine management is not evidence-based and is disseminated by for-profit organizations. As healthcare professionals and members of professional headache organizations, we are obliged to prioritize knowledge dissemination. A progressive social media strategy is associated not only with increased online visibility and outreach, but also with a higher scientific interest. To identify gaps and barriers, future research should assess the range of available information on headache disorders in electronic media, characterize direct and indirect consequences on clinical management, and recognize best practice and strategies to improve our communication on internet-based communication platforms. In turn, these efforts will reduce the burden of headache disorders by facilitating improved education of both patients and providers.
    MeSH term(s) Humans ; United States ; Headache Disorders ; Social Media ; Migraine Disorders ; Health Personnel ; Headache/therapy
    Language English
    Publishing date 2023-05-17
    Publishing country England
    Document type Letter
    ZDB-ID 2041347-6
    ISSN 1471-2377 ; 1471-2377
    ISSN (online) 1471-2377
    ISSN 1471-2377
    DOI 10.1186/s12883-023-03196-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Revisiting dose-finding of monoclonal antibodies in migraine.

    Al-Hassany, Linda / Karsan, Nazia / Lampl, Christian / Goadsby, Peter J / MaassenVanDenBrink, Antoinette

    The journal of headache and pain

    2023  Volume 24, Issue 1, Page(s) 69

    Abstract: Migraine is a debilitating disorder, and while the introduction of monoclonal antibodies (mAbs) has led to efficacious and tolerable responses, a substantial number of patients are so-called "non-responders". We introduce reasons for this insufficient ... ...

    Abstract Migraine is a debilitating disorder, and while the introduction of monoclonal antibodies (mAbs) has led to efficacious and tolerable responses, a substantial number of patients are so-called "non-responders". We introduce reasons for this insufficient response, including insufficient blockade of Calcitonin Gene-Related Peptide (CGRP) or its receptor. We present a clinical case, i.e. a female migraine patient who mistakenly administered supratherapeutic (three-fold higher) doses of erenumab leading to more efficacious clinical responses without any side-effects. This example illustrates that the initial dosages might have been too low, resulting in a remaining undesired increased effect of CGRP. While a capsaicin forearm model has repeatedly been used to evaluate the pharmacokinetic-pharmacodynamic relationship of mAbs, we provide directions to revisit or reconsider dose-finding and dose-ranging of these drugs. These directions include (i) refinement and application of a capsaicin forehead model (instead of a forearm model) to study trigeminovascular activity and improve dosing, and (ii) reconsideration of trial populations. Indeed, the dose-finding studies were mainly performed in relatively young and normal-weight males, while most phase III/IV trials are marked by a high female-to-male ratio, mainly consisting of overweight to obese females. Considering these aspects in future trials could optimize healthcare for a larger proportion of migraine patients.
    MeSH term(s) Humans ; Male ; Female ; Antibodies, Monoclonal/therapeutic use ; Calcitonin Gene-Related Peptide/therapeutic use ; Capsaicin ; Receptors, Calcitonin Gene-Related Peptide ; Migraine Disorders/drug therapy
    Chemical Substances Antibodies, Monoclonal ; Calcitonin Gene-Related Peptide (JHB2QIZ69Z) ; Capsaicin (S07O44R1ZM) ; Receptors, Calcitonin Gene-Related Peptide
    Language English
    Publishing date 2023-06-09
    Publishing country England
    Document type Letter
    ZDB-ID 2036768-5
    ISSN 1129-2377 ; 1129-2369
    ISSN (online) 1129-2377
    ISSN 1129-2369
    DOI 10.1186/s10194-023-01602-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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