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  1. Article ; Online: Detection of Influenza D Antibodies in Dogs, Apulia Region, Italy, 2016 and 2023.

    Trombetta, Claudia Maria / Marchi, Serena / Marotta, Maria Giovanna / Moreno, Ana / Chiapponi, Chiara / Montomoli, Emanuele / Lanave, Gianvito / Camero, Michele / Martella, Vito

    Emerging infectious diseases

    2024  Volume 30, Issue 5, Page(s) 1045–1047

    Abstract: Dogs are known to be susceptible to influenza A viruses, although information on influenza D virus (IDV) is limited. We investigated the seroprevalence of IDV in 426 dogs in the Apulia region of Italy during 2016 and 2023. A total of 14 samples were ... ...

    Abstract Dogs are known to be susceptible to influenza A viruses, although information on influenza D virus (IDV) is limited. We investigated the seroprevalence of IDV in 426 dogs in the Apulia region of Italy during 2016 and 2023. A total of 14 samples were positive for IDV antibodies, suggesting exposure to IDV in dogs.
    MeSH term(s) Dogs ; Animals ; Italy/epidemiology ; Orthomyxoviridae Infections/veterinary ; Orthomyxoviridae Infections/epidemiology ; Orthomyxoviridae Infections/virology ; Orthomyxoviridae Infections/immunology ; Dog Diseases/epidemiology ; Dog Diseases/virology ; Antibodies, Viral/blood ; Seroepidemiologic Studies ; Thogotovirus/immunology
    Chemical Substances Antibodies, Viral
    Language English
    Publishing date 2024-04-26
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1380686-5
    ISSN 1080-6059 ; 1080-6040
    ISSN (online) 1080-6059
    ISSN 1080-6040
    DOI 10.3201/eid3005.231401
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Detection of vesivirus in minks (Neovison vison), Italy 2021.

    Ripà, Paola / Perugini, Francesco / Decaro, Nicola / Curini, Valentina / Ruberto, Addolorato / Marcacci, Maurilia / Martella, Vito / Lorusso, Alessio / Lanave, Gianvito

    Veterinaria italiana

    2024  Volume 60, Issue 1

    Abstract: Vesiviruses are important animal pathogens with a broad host range, and they have also been involved in accidental contamination of cells used for the production of drugs for rare and life-threatening human diseases. A vesivirus (family Caliciviridae) ... ...

    Abstract Vesiviruses are important animal pathogens with a broad host range, and they have also been involved in accidental contamination of cells used for the production of drugs for rare and life-threatening human diseases. A vesivirus (family Caliciviridae) was detected in minks (Neovison vison) with respiratory and neurological signs, during syndromic surveillance for SARS-CoV-2 conducted in Italy. The complete genome (8,397 nucleotides in length) of the vesivirus strain ITA/2021/mink/TE (OR130287) was obtained by combining NGS approach with 5' and 3' RACE protocols. The virus was seemingly more related (95.9-97.2% nt identity in the partial RNA-dependent RNA polymerase) to American vesivirus isolates 9/1980/US, 12/1980/US, and 20/1980/US dating back to the early 1980s than to recent mink strains. These results highlight the importance of gathering information on the virome of animals.
    MeSH term(s) Animals ; Humans ; Mink ; Vesivirus/genetics ; Italy
    Language English
    Publishing date 2024-03-31
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2536397-9
    ISSN 1828-1427 ; 0505-401X
    ISSN (online) 1828-1427
    ISSN 0505-401X
    DOI 10.12834/VetIt.3472.23552.1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Mechanism of surfactant interactions with feline coronavirus: A physical chemistry perspective.

    Mateos, Helena / Mallardi, Antonia / Camero, Michele / Lanave, Gianvito / Catella, Cristiana / Buonavoglia, Alessio / De Giglio, Osvalda / Buonavoglia, Canio / Palazzo, Gerardo

    Journal of colloid and interface science

    2024  Volume 662, Page(s) 535–544

    Abstract: Hypothesis: Surfactants are inexpensive chemicals with promising applications in virus inactivation, particularly for enveloped viruses. Yet, the detailed mechanisms by which surfactants deactivate coronaviruses remain underexplored. This study delves ... ...

    Abstract Hypothesis: Surfactants are inexpensive chemicals with promising applications in virus inactivation, particularly for enveloped viruses. Yet, the detailed mechanisms by which surfactants deactivate coronaviruses remain underexplored. This study delves into the virucidal mechanisms of various surfactants on Feline Coronavirus (FCoV) and their potential applications against more pathogenic coronaviruses.
    Experiments: By integrating virucidal activity assays with fluorescence spectroscopy, dynamic light scattering and laser Doppler electrophoresis, alongside liposome permeability experiments, we have analyzed the effects of non-ionic and ionic surfactants on viral activity.
    Findings: The non-ionic surfactant octaethylene glycol monodecyl ether (C
    MeSH term(s) Animals ; Cats ; Surface-Active Agents/pharmacology ; Surface-Active Agents/chemistry ; Coronavirus, Feline/physiology ; Sodium Dodecyl Sulfate ; Virus Inactivation
    Chemical Substances Surface-Active Agents ; Sodium Dodecyl Sulfate (368GB5141J)
    Language English
    Publishing date 2024-02-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 241597-5
    ISSN 1095-7103 ; 0021-9797
    ISSN (online) 1095-7103
    ISSN 0021-9797
    DOI 10.1016/j.jcis.2024.02.088
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Domestic Cat Hepadnavirus: Molecular Epidemiology and Phylogeny in Cats in Hong Kong.

    Capozza, Paolo / Carrai, Maura / Choi, Yan Ru / Tu, Thomas / Nekouei, Omid / Lanave, Gianvito / Martella, Vito / Beatty, Julia A / Barrs, Vanessa R

    Viruses

    2023  Volume 15, Issue 1

    Abstract: Domestic cat hepadnavirus (DCH) is an emerging virus related to the hepatitis B virus (HBV). The pathogenic potential of DCH in cats remains to be established. The molecular prevalence of DCH varies widely in the regions investigated so far. The aim of ... ...

    Abstract Domestic cat hepadnavirus (DCH) is an emerging virus related to the hepatitis B virus (HBV). The pathogenic potential of DCH in cats remains to be established. The molecular prevalence of DCH varies widely in the regions investigated so far. The aim of this study was to determine the prevalence, load, and risk factors for DCH detection among cats in Hong Kong, and to generate molecular and epidemiological data on the DCH strains circulating in cats in Hong Kong. DCH DNA was detected using DCH-specific qPCR in 57/513 (11.1%) residual diagnostic blood samples from owned cats. The median viral load was 8.85 × 10
    MeSH term(s) Cats ; Animals ; Humans ; Hong Kong/epidemiology ; Phylogeny ; Hepadnaviridae/genetics ; Molecular Epidemiology ; Risk Factors
    Language English
    Publishing date 2023-01-03
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v15010150
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Identification of

    Lanave, Gianvito / Pellegrini, Francesco / Palermo, Giuseppe / Zini, Eric / Mercuriali, Edy / Zagarella, Paolo / Bányai, Krisztián / Camero, Michele / Martella, Vito

    Veterinary sciences

    2023  Volume 10, Issue 12

    Abstract: Prototheca infections are rare in cats, and they are usually associated with cutaneous or subcutaneous infections ... ...

    Abstract Prototheca infections are rare in cats, and they are usually associated with cutaneous or subcutaneous infections by
    Language English
    Publishing date 2023-11-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2768971-2
    ISSN 2306-7381 ; 2306-7381
    ISSN (online) 2306-7381
    ISSN 2306-7381
    DOI 10.3390/vetsci10120681
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Feline Coronavirus and Alpha-Herpesvirus Infections: Innate Immune Response and Immune Escape Mechanisms

    Capozza, Paolo / Pratelli, Annamaria / Camero, Michele / Lanave, Gianvito / Greco, Grazia / Pellegrini, Francesco / Tempesta, Maria

    Animals. 2021 Dec. 14, v. 11, no. 12

    2021  

    Abstract: Over time, feline viruses have acquired elaborateopportunistic properties, making their infections particularly difficult to prevent and treat. Feline coronavirus (FCoV) and feline herpesvirus-1 (FeHV-1), due to the involvement of host genetic factors ... ...

    Abstract Over time, feline viruses have acquired elaborateopportunistic properties, making their infections particularly difficult to prevent and treat. Feline coronavirus (FCoV) and feline herpesvirus-1 (FeHV-1), due to the involvement of host genetic factors and immune mechanisms in the development of the disease and more severe forms, are important examples of immune evasion of the host’s innate immune response by feline viruses.It is widely accepted that the innate immune system, which providesan initial universal form of the mammalian host protection from infectious diseases without pre-exposure, plays an essential role in determining the outcome of viral infection.The main components of this immune systembranchare represented by the internal sensors of the host cells that are able to perceive the presence of viral component, including nucleic acids, to start and trigger the production of first type interferon and to activate the cytotoxicity by Natural Killercells, often exploited by viruses for immune evasion.In this brief review, we providea general overview of the principal tools of innate immunity, focusing on the immunologic escape implemented byFCoVand FeHV-1 duringinfection.
    Keywords Felid alphaherpesvirus 1 ; Feline coronavirus ; cats ; cytotoxicity ; immune evasion ; innate immunity ; interferons
    Language English
    Dates of publication 2021-1214
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani11123548
    Database NAL-Catalogue (AGRICOLA)

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  7. Article ; Online: First serological evidence of Crimean–Congo haemorrhagic fever virus in transhumant bovines in Italy

    Fanelli, Angela / Buonavoglia, Domenico / Lanave, Gianvito / Monaco, Federica / Quaranta, Vincenzo / Catanzariti, Roberta / Ruiz‐Fons, Francisco / Buonavoglia, Canio

    Transboundary and Emerging Diseases. 2022 Nov., v. 69, no. 6 p.4022-4027

    2022  

    Abstract: Crimean–Congo haemorrhagic fever (CCHF) is an emerging tick‐borne disease caused by the arbovirus Crimean–Congo haemorrhagic fever virus (CCHFV; family Nairoviridae). Given the public health impact, CCHF is considered a priority disease for the European ... ...

    Abstract Crimean–Congo haemorrhagic fever (CCHF) is an emerging tick‐borne disease caused by the arbovirus Crimean–Congo haemorrhagic fever virus (CCHFV; family Nairoviridae). Given the public health impact, CCHF is considered a priority disease for the European Union. This study describes the first detection of anti‐CCHFV antibodies in transhumant bovines in Italy. Sera from 794 cattle collected across Basilicata region (Southern Italy) were screened using a commercial ELISA kit. The animal‐level and herd‐level seroprevalences detected were 1.89% [95%CI: 1.12–3.1] and 29.63% [95%CI: 15.68–48.65], respectively. Results of the χ² test for trend show that the exposure to CCHFV was significantly associated with increasing age, with the odds 5 times higher in 11–22‐year old cattle than 1–4‐year old cattle. The detection of antibodies against CCHFV in indigenous cattle indicates that the infection occurred in the study area and may warrant further consideration. Additionally, no significant spatial clustering of CCHF infection was detected, supporting the hypothesis that the disease is widespread in the region. Further studies at larger scale are needed to identify the areas at higher risk of zoonotic infection. A One Health approach should be implemented to better understand the disease risk and dynamics in the country, which effectively address the related public health threat.
    Keywords Crimean-Congo hemorrhagic fever ; Crimean-Congo hemorrhagic fever orthonairovirus ; European Union ; One Health initiative ; arboviruses ; cattle ; enzyme-linked immunosorbent assay ; public health ; risk ; tick-borne diseases ; zoonoses ; Italy
    Language English
    Dates of publication 2022-11
    Size p. 4022-4027.
    Publishing place John Wiley & Sons, Ltd
    Document type Article ; Online
    Note JOURNAL ARTICLE
    ZDB-ID 2414822-2
    ISSN 1865-1682 ; 1865-1674
    ISSN (online) 1865-1682
    ISSN 1865-1674
    DOI 10.1111/tbed.14710
    Database NAL-Catalogue (AGRICOLA)

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  8. Article ; Online: In Vitro Activity of Ozone/Oxygen Gaseous Mixture against a Caprine Herpesvirus Type 1 Strain Isolated from a Goat with Vaginitis

    Lillo, Edoardo / Pellegrini, Francesco / Rizzo, Annalisa / Lanave, Gianvito / Zizzadoro, Claudia / Cicirelli, Vincenzo / Catella, Cristiana / Losurdo, Michele / Martella, Vito / Tempesta, Maria / Camero, Michele

    Animals. 2023 June 08, v. 13, no. 12

    2023  

    Abstract: Alphaherpesviruses cause genital lesions and reproductive failure in both humans and animals. Their control is mainly based on prevention using hygienic prophylactic measures due to the absence of vaccines and limitations of antiviral drug therapy. Ozone ...

    Abstract Alphaherpesviruses cause genital lesions and reproductive failure in both humans and animals. Their control is mainly based on prevention using hygienic prophylactic measures due to the absence of vaccines and limitations of antiviral drug therapy. Ozone is an oxidating gas showing a strong microbicidal activity on bacteria, fungi, viruses, and protozoa. The present study assessed the in vitro virucidal and antiviral activity of ozone against caprine herpesvirus type 1 (CpHV-1). The virucidal activity of a gaseous mixture containing O₃ at 20 and 50 μg/mL was assessed against the virus at different contact times (30 s, 60 s, 90 s, 120 s, 180 s, and 300 s). Antiviral activity of a gaseous mixture containing O₃ at 20 and 50 μg/mL was evaluated against the virus after 30 s and 60 s. Ozone displayed significant virucidal activity when used at all the tested concentrations whilst significant antiviral activity was observed using ozone at 50 μg/mL. The gaseous mixture, tested in the present study, showed virucidal and antiviral activity against CpHV-1 in a dose- and time contact-dependent fashion. Ozone therapy could be evaluated in vivo for the treatment of CpHV-1-induced genital lesions in goats using topical applications.
    Keywords Caprine alphaherpesvirus 1 ; Protozoa ; antiviral agents ; antiviral properties ; drug therapy ; hygiene ; oxygen ; ozone ; vaginitis ; viruses
    Language English
    Dates of publication 2023-0608
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article ; Online
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani13121920
    Database NAL-Catalogue (AGRICOLA)

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  9. Article: In Vitro Antiviral and Virucidal Activity of Ozone against Feline Calicivirus.

    Catella, Cristiana / Pellegrini, Francesco / Carbonari, Alice / Burgio, Matteo / Patruno, Giovanni / Rizzo, Annalisa / Trombetta, Claudia Maria / Palmisani, Jolanda / Martella, Vito / Camero, Michele / Lanave, Gianvito

    Animals : an open access journal from MDPI

    2024  Volume 14, Issue 5

    Abstract: ... ...

    Abstract The
    Language English
    Publishing date 2024-02-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani14050682
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Serological Evidence for Circulation of Influenza D Virus in the Ovine Population in Italy.

    Lanave, Gianvito / Camero, Michele / Coppola, Chiara / Marchi, Serena / Cascone, Giuseppe / Salina, Felice / Coltraro, Miriana / Odigie, Amienwanlen E / Montomoli, Emanuele / Chiapponi, Chiara / Cicirelli, Vincenzo / Martella, Vito / Trombetta, Claudia M

    Pathogens (Basel, Switzerland)

    2024  Volume 13, Issue 2

    Abstract: Influenza D virus (IDV) is a novel orthomyxovirus initially isolated from pigs exhibiting influenza-like disease in the USA. Since then, IDV has been detected worldwide in several host species, including livestock animals, whilst specific antibodies have ...

    Abstract Influenza D virus (IDV) is a novel orthomyxovirus initially isolated from pigs exhibiting influenza-like disease in the USA. Since then, IDV has been detected worldwide in several host species, including livestock animals, whilst specific antibodies have been identified in humans, raising concerns about interspecies transmission and zoonotic risks. Few data regarding the seroprevalence of IDV in small ruminants have been available to date. In this study, we assessed the prevalence of antibodies against IDV in ovine serum samples in Sicily, Southern Italy. Six hundred serum samples, collected from dairy sheep herds located in Sicily in 2022, were tested by haemagglutination inhibition (HI) and virus neutralization (VN) assays using reference strains, D/660 and D/OK, representative of two distinct IDV lineages circulating in Italy. Out of 600 tested samples, 168 (28.0%) tested positive to either IDV strain D/660 or D/OK or to both by HI whilst 378 (63.0%) tested positive to either IDV strain D/660 or D/OK or to both by VN. Overall, our findings demonstrate that IDV circulates in ovine dairy herds in Sicily. Since IDV seems to have a broad host range and it has zoonotic potential, it is important to collect epidemiological information on susceptible species.
    Language English
    Publishing date 2024-02-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens13020162
    Database MEDical Literature Analysis and Retrieval System OnLINE

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