LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 2 of total 2

Search options

  1. Article ; Online: Monkeypox and ocular implications in humans.

    Ci Ng, Faye Yu / Yeh, Steven / Smit, Derrick / Ng, Oon Tek / Vasoo, Shawn / Land Curi, Andre Luiz / Agrawal, Rupesh

    The ocular surface

    2022  Volume 27, Page(s) 13–15

    MeSH term(s) Humans ; Mpox (monkeypox) ; Eye
    Language English
    Publishing date 2022-11-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2208578-6
    ISSN 1937-5913 ; 1542-0124
    ISSN (online) 1937-5913
    ISSN 1542-0124
    DOI 10.1016/j.jtos.2022.10.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 6458: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Toxoplasmic retinochoroiditis: The influence of age, number of retinochoroidal lesions and genetic polymorphism for IFN-γ +874 T/A as risk factors for recurrence in a survival analysis.

    Aleixo, Ana Luisa Quintella do Couto / Vasconcelos C de Oliveira, Raquel / Cavalcanti Albuquerque, Maíra / Biancardi, Ana Luiza / Land Curi, André Luiz / Israel Benchimol, Eliezer / Reis Amendoeira, Maria Regina

    PloS one

    2019  Volume 14, Issue 2, Page(s) e0211627

    Abstract: Purpose: To analyze risk factors for recurrent toxoplasmic retinochoroiditis.: Design: Single center prospective case series.: Population and methods: A total of 230 patients with toxoplasmic retinochoroiditis were prospectively followed to assess ...

    Abstract Purpose: To analyze risk factors for recurrent toxoplasmic retinochoroiditis.
    Design: Single center prospective case series.
    Population and methods: A total of 230 patients with toxoplasmic retinochoroiditis were prospectively followed to assess recurrences. All patients were treated with a specific drug regime for toxoplasmosis in each episode of active retinochoroiditis. Individuals with chronic diseases and pregnant women were excluded. Survival analysis by extended Cox regression model (Prentice-Williams-Peterson counting process model) was performed to evaluate the time between recurrences according to some potential risk factors: age, number of retinochoroidal lesions at initial evaluation, sex and interferon gamma +874 T/A gene polymorphism. Hazard Ratios (HR) and 95% confidence intervals (CI) were provided to interpret the risk effects.
    Results: One hundred sixty-two recurrence episodes were observed in 104 (45.2%) patients during follow-up that lasted from 269 to 1976 days. Mean age at presentation was 32.8 years (Standard deviation = 11.38). The risk of recurrence during follow up was influenced by age (HR = 1.02, 95% CI = 1.01-1.04) and number of retinochoroidal lesions at the beginning of the study (HR = 1.60, 95% CI = 1.07-2.40). Heterozygosis for IFN-γ gene polymorphism at position +874 T/A was also associated with recurrence (HR = 1.49, 95% CI = 1.04-2.14).
    Conclusion: The risk of ocular toxoplasmosis recurrence after an active episode increased with age and was significantly higher in individuals with primary lesions, which suggests that individuals with this characteristic and the elderly could benefit from recurrence prophylactic strategies with antimicrobials. Results suggest an association between IFN-γ gene polymorphism at position +874T/A and recurrence.
    MeSH term(s) Adolescent ; Anti-Infective Agents/therapeutic use ; Chorioretinitis/drug therapy ; Chorioretinitis/genetics ; Female ; Humans ; Interferon-gamma/genetics ; Male ; Polymorphism, Genetic/genetics ; Prospective Studies ; Recurrence ; Risk Factors ; Survival Analysis ; Toxoplasmosis, Ocular/drug therapy ; Toxoplasmosis, Ocular/genetics ; Visual Acuity/genetics
    Chemical Substances Anti-Infective Agents ; Interferon-gamma (82115-62-6)
    Language English
    Publishing date 2019-02-12
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0211627
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top