Article: Chronic cough associated with COPD exacerbation, pneumonia and death in the general population.
2024 Volume 10, Issue 1
Abstract: Background: Chronic cough affects up to 10% of the general population and was previously perceived as a comorbidity of underlying conditions, but is nowadays classified as a disease in its own entity that could confer increased risk of morbidity and ... ...
| Abstract | Background: Chronic cough affects up to 10% of the general population and was previously perceived as a comorbidity of underlying conditions, but is nowadays classified as a disease in its own entity that could confer increased risk of morbidity and mortality. We tested the hypothesis that chronic cough is associated with increased risk of COPD exacerbation, pneumonia and all-cause mortality in the general population. Methods: We identified 2801 individuals with chronic cough, defined as cough lasting >8 weeks, among 44 756 randomly selected individuals from the Copenhagen General Population Study, and recorded COPD exacerbations, pneumonia and all-cause mortality during follow-up. Results: During up to 5.9 years of follow-up (median 3.4 years), 173 individuals experienced COPD exacerbation, 767 experienced pneumonia and 894 individuals died. Individuals with chronic cough Conclusion: Chronic cough is associated with higher risks of COPD exacerbation, pneumonia and death, independent of airflow limitation and smoking. |
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| Language | English |
| Publishing date | 2024-02-05 |
| Publishing country | England |
| Document type | Journal Article |
| ZDB-ID | 2827830-6 |
| ISSN | 2312-0541 |
| ISSN | 2312-0541 |
| DOI | 10.1183/23120541.00697-2023 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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