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  1. Article: 3D-printed metals: Process parameters effects on mechanical properties of 17-4 P H stainless steel.

    Andreacola, Francesca Romana / Capasso, Ilaria / Langella, Antonio / Brando, Giuseppe

    Heliyon

    2023  Volume 9, Issue 7, Page(s) e17698

    Abstract: Additive Manufacturing (AM) has spread significantly in recent years, with relevant applications in many fields of research and engineering. Thanks to its distinctive production methods, AM enables the creation of parts with complex shapes that cannot be ...

    Abstract Additive Manufacturing (AM) has spread significantly in recent years, with relevant applications in many fields of research and engineering. Thanks to its distinctive production methods, AM enables the creation of parts with complex shapes that cannot be fabricated easily by employing traditional subtractive processes. 3D printing, which involves overlapping material layer by layer until the designed part is completed, shows several advantages in terms of limiting material waste, reducing production phases and postprocessing/heat treatments needs, leading to an additional benefit in terms of environmental sustainability. However, there are still limited available data on the influence of the 3D printing process on the mechanical properties of the materials that are commonly used and additional investigations are strongly demanded. So, the purpose of the present paper is to provide a useful contribution in the field of metal additive manufacturing, reporting the results of an experimental campaign carried out on 17-4 P H stainless steel, produced using selective laser melting technology. The effects of different printing orientations and scanning times on the tensile behaviour, impact strength and microhardness features of the 3D-printed products are investigated. Furthermore, the influence of an annealing heat treatment on the material mechanical performance is evaluated.
    Language English
    Publishing date 2023-07-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e17698
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Investigating strontium isotope linkage between biominerals (uroliths), drinking water and environmental matrices.

    Izzo, F / Di Renzo, V / Langella, A / D'Antonio, M / Tranfa, P / Widory, D / Salzano, L / Germinario, C / Grifa, C / Varricchio, E / Mercurio, M

    Environmental pollution (Barking, Essex : 1987)

    2024  Volume 344, Page(s) 123316

    Abstract: This study presents the mineralogy and strontium isotope ratio ( ...

    Abstract This study presents the mineralogy and strontium isotope ratio (
    MeSH term(s) Animals ; Humans ; Drinking Water ; Strontium Isotopes/analysis ; Isotopes ; Agriculture ; Urinary Calculi ; Strontium
    Chemical Substances Drinking Water ; Strontium Isotopes ; Isotopes ; Strontium (YZS2RPE8LE)
    Language English
    Publishing date 2024-01-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 280652-6
    ISSN 1873-6424 ; 0013-9327 ; 0269-7491
    ISSN (online) 1873-6424
    ISSN 0013-9327 ; 0269-7491
    DOI 10.1016/j.envpol.2024.123316
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: COVID: Using the DAN Model with Couples to Increase Family Resilience.

    Mariotti, Mauro / Muratori, Greco / Langella, Achille / Scaltriti, Nicoletta

    The Australian and New Zealand journal of family therapy

    2021  Volume 42, Issue 1, Page(s) 44–57

    Abstract: The COVID-19 pandemic has massively impacted our society, affecting both wider systems and smaller ones alike. Families across the world have had to adapt to a new style of living, dominated by uncertainty, which is testing their resilience. Within this ... ...

    Abstract The COVID-19 pandemic has massively impacted our society, affecting both wider systems and smaller ones alike. Families across the world have had to adapt to a new style of living, dominated by uncertainty, which is testing their resilience. Within this context, we have asked ourselves, as systemic therapists, what can be done to provide support and a sense of understanding to families. In this article, it is argued that therapeutic tools taken from a manualised intervention to promote resilience in couples can provide valuable help to families who are struggling in this difficult time. This intervention, developed at the Iscra Institute in Modena, Italy, is called Digital, Analogic, and Narrative (DAN). The tools used in the DAN model are described in this paper and their application in practice is illustrated through a case study.
    Language English
    Publishing date 2021-03-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2089783-2
    ISSN 1467-8438 ; 0814-723X ; 0156-8779
    ISSN (online) 1467-8438
    ISSN 0814-723X ; 0156-8779
    DOI 10.1002/anzf.1436
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  4. Article ; Online: Investigation on the Mechanical Recycling of Carbon Fiber-Reinforced Polymers by Peripheral Down-Milling.

    Durante, Massimo / Boccarusso, Luca / De Fazio, Dario / Formisano, Antonio / Langella, Antonio

    Polymers

    2023  Volume 15, Issue 4

    Abstract: Carbon fiber-reinforced plastics (CFRPs) are composite materials that play a significant role in the growth of many industrial fields where high performance and lightness of the structures are required. At the same time, the management at the end of ... ...

    Abstract Carbon fiber-reinforced plastics (CFRPs) are composite materials that play a significant role in the growth of many industrial fields where high performance and lightness of the structures are required. At the same time, the management at the end of their life has required the development of more and more sustainable and efficient recycling solutions. Considering this, the present research work aims to investigate a mechanical recycling method and the cutting strategies able to machine CFRP components in their entirety, using a common milling machine in a job shop scheme, making a shorter supply chain, and leading to economic and environmental benefits. In detail, laminates obtained by unidirectional carbon fiber prepregs were worked through the peripheral down-milling process, by varying the spindle speed and the feed rate. The recording of the cutting forces enabled the evaluation of features such as the cutting power and the specific cutting energy. Moreover, the chips from the milling process were classified as a function of their dimensions. Finally, specimens made of chips and epoxy resin were characterized under bending conditions, to evaluate the effectiveness of using the chips from CFRP peripheral milling as the polymer's reinforcement and, in addition, to appreciate the goodness of this recycling strategy.
    Language English
    Publishing date 2023-02-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym15040854
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: First-principles design of nanostructured electrode materials for Na-ion batteries: challenges and perspectives.

    Massaro, Arianna / Fasulo, Francesca / Pecoraro, Adriana / Langella, Aniello / Muñoz-García, Ana B / Pavone, Michele

    Physical chemistry chemical physics : PCCP

    2023  Volume 25, Issue 28, Page(s) 18623–18641

    Abstract: Post-lithium batteries are emerging as viable solutions for sustainable energy transition. Effective deployment in the market calls for great research efforts in the identification of novel component materials and the assessment of related working ... ...

    Abstract Post-lithium batteries are emerging as viable solutions for sustainable energy transition. Effective deployment in the market calls for great research efforts in the identification of novel component materials and the assessment of related working principles. Computational modelling can be a key player in boosting innovation and development by enabling rational strategies for the design of appropriately tuned materials with optimized activity towards battery operating processes. By gaining access to the structural and electronic features of functional electrodes, state-of-the-art DFT methods can unveil the subtle structure-property relationship that affects the uptake, transport, and storage efficiency. Hereby, we aim at reviewing the research status of theoretical advances in the field of Na-ion batteries (NIBs) and illustrating to what extent atomistic insights into sodiation/desodiation mechanisms of nanostructured materials can assist the development of effective anodes and cathodes for stable and highly performing devices. Thanks to increasing computer power and fruitful cooperation between theory and experiments, the route for effective design methodologies is being paved and will feed the upcoming developments in NIB technology.
    Language English
    Publishing date 2023-07-19
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1476244-4
    ISSN 1463-9084 ; 1463-9076
    ISSN (online) 1463-9084
    ISSN 1463-9076
    DOI 10.1039/d3cp01201h
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Microtubular Assessment of C6 Rat Glioma Cell Spheroids Developed in Transparent Liquid Marbles or Hanging Drops.

    Langella, Arianna / Gadau, Sergio Domenico / Serra, Elisa / Bebbere, Daniela / Ledda, Sergio

    Biology

    2022  Volume 11, Issue 4

    Abstract: Glioblastoma is a brain tumour frequently used as an experimental model to exploit innovative therapeutic approaches due to its high lethality and refractoriness to therapies. Part of these innovative anticancer therapies address cytoskeletal ... ...

    Abstract Glioblastoma is a brain tumour frequently used as an experimental model to exploit innovative therapeutic approaches due to its high lethality and refractoriness to therapies. Part of these innovative anticancer therapies address cytoskeletal microtubules (MTs) since specific tubulin post-translational modifications (PTMs) are considered markers of tumour plasticity. In vitro studies, which traditionally employ two-dimensional (2D) culture systems, are now being replaced by three-dimensional (3D) systems that more closely mimic in vivo physiological conditions and allow a better understanding of the signalling between cells. In this work, we compared 2 liquid base 3D methods for the generation of spheroids from C6 rat glioma cells (RGCs) using 30 µL of liquid marble (LM) or the hanging drops (HDs), which contained 2 different cell numbers (5000 or 15,000). After 24 or 48 h of in vitro culture (IVC), the morphology of the spheroids was observed and the behaviour of the two main tubulin PTMs, tyrosinated α-tubulin (Tyr-T) and acetylated α-tubulin (Ac-T), was evaluated by fluorescence and Western blot (WB). RGCs spontaneously formed spherical agglomerates more rapidly in the LM than in the HD system. Cell density influenced the size of the spheroids, which reached a larger size (> of 300 µm Ø), with 15,000 cells compared to 5000 cells (150 µm Ø). Moreover, an increase in Tyr-T and Ac-T was observed in both the HD and LM system from 24 to 48 h, with the highest values shown in the 48 h/LM spheroids of 5000 cells (p < 0.05). In conclusion, by comparing the morphology and microtubular architecture of spheroids from C6 rat glioma cells developed by LM or HD methodology, our findings demonstrate that the use of a fumed silica microbioreactor boosts the induction and maintenance of a high plasticity state in glioma cells. RGCs cultured in LM express levels of tubulin PTMs that can be used to evaluate the efficacy of new anticancer therapies.
    Language English
    Publishing date 2022-03-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2661517-4
    ISSN 2079-7737
    ISSN 2079-7737
    DOI 10.3390/biology11040492
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  7. Article: Use of Zeolites in the Capture and Storage of Thermal Energy by Water Desorption-Adsorption Cycles.

    de Gennaro, Bruno / Cappi, Angelo / de Gennaro, Maurizio / Bianco, Nicola / Langella, Alessio / Cappelletti, Piergiulio / Marocco, Antonello / Aprea, Paolo / Pansini, Michele

    Materials (Basel, Switzerland)

    2022  Volume 15, Issue 16

    Abstract: In this work, four zeolite-bearing materials (three naturally occurring and one of synthetic origin) were considered for thermal energy capture and storage. Such materials can store thermal energy as heat of desorption of the water present therein, heat ... ...

    Abstract In this work, four zeolite-bearing materials (three naturally occurring and one of synthetic origin) were considered for thermal energy capture and storage. Such materials can store thermal energy as heat of desorption of the water present therein, heat that is given back when water vapor is allowed to be re-adsorbed by zeolites. This study was carried out by determining the loss of water after different activation thermal treatments, the water adsorption kinetics and isotherm after an activation step of the zeolites, the intergranular and intragranular porosity, and the thermal conductivity of the zeolite-bearing materials. Moreover, the thermal stability of the framework of the zeolites of the four materials tested was investigated over a large number of thermal cycles. The results indicate that zeolite 13X was the most suitable material for thermal energy storage and suggest its use in the capture and storage of thermal energy that derives from thermal energy waste.
    Language English
    Publishing date 2022-08-13
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma15165574
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  8. Article ; Online: May a comprehensive mineralogical study of a jackstone calculus and some other human bladder stones unveil health and environmental implications?

    Mercurio, M / Izzo, F / Gatta, Giacomo Diego / Salzano, L / Lotrecchiano, G / Saldutto, P / Germinario, C / Grifa, C / Varricchio, E / Carafa, A / Di Meo, Maria Chiara / Langella, A

    Environmental geochemistry and health

    2021  Volume 44, Issue 10, Page(s) 3297–3320

    Abstract: This paper represents the first result of an active collaboration between the University of Sannio and the San Pio Hospital (Benevento, Italy), started in the 2018, that aims to a detailed mineralogical investigation of urinary stones of patients from ... ...

    Abstract This paper represents the first result of an active collaboration between the University of Sannio and the San Pio Hospital (Benevento, Italy), started in the 2018, that aims to a detailed mineralogical investigation of urinary stones of patients from Campania region. Herein, selected human bladder stones have been deeply characterized for clinical purposes and environmental biomonitoring, focusing on the importance to evaluate the concentration and distribution of undesired trace elements by means of microscopic techniques in the place of conventional wet chemical analyses. A rare bladder stone with a sea-urchin appearance, known as jackstone calculus, were also investigated (along with bladder stones made of uric acid and brushite) by means a comprehensive analytical approach, including Synchrotron X-ray Diffraction and Simultaneous Thermal Analyses. Main clinical assumptions were inferred according to the morpho-constitutional classification of bladder stones and information about patient's medical history and lifestyle. In most of the analyzed uroliths, undesired trace elements such as copper, cadmium, lead, chromium, mercury and arsenic have been detected and generally attributable to environmental pollution or contaminated food. Simultaneous occurrence of selenium and mercury should denote a methylmercury detoxification process, probably leading to the formation of a very rare HgSe compound known as tiemannite.
    MeSH term(s) Arsenic ; Cadmium ; Chromium ; Copper ; Humans ; Mercury ; Methylmercury Compounds ; Selenium ; Trace Elements ; Uric Acid/analysis ; Urinary Bladder Calculi ; Urinary Calculi/chemistry ; Urinary Calculi/epidemiology
    Chemical Substances Methylmercury Compounds ; Trace Elements ; Cadmium (00BH33GNGH) ; Chromium (0R0008Q3JB) ; Uric Acid (268B43MJ25) ; Copper (789U1901C5) ; Mercury (FXS1BY2PGL) ; Selenium (H6241UJ22B) ; Arsenic (N712M78A8G)
    Language English
    Publishing date 2021-09-16
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 52039-1
    ISSN 1573-2983 ; 0142-7245 ; 0269-4042
    ISSN (online) 1573-2983
    ISSN 0142-7245 ; 0269-4042
    DOI 10.1007/s10653-021-01083-x
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  9. Article ; Online: Removal of non-steroidal anti-inflammatory drugs from water by zeolite-rich composites: The interference of inorganic anions on the ibuprofen and naproxen adsorption.

    Smiljanić, Danijela / de Gennaro, Bruno / Daković, Aleksandra / Galzerano, Barbara / Germinario, Chiara / Izzo, Francesco / Rottinghaus, George E / Langella, Alessio

    Journal of environmental management

    2021  Volume 286, Page(s) 112168

    Abstract: Composites of two natural zeolites - clinoptilolite and phillipsite, and cationic surfactants (cetylpyridinium chloride and Arquad® 2HT-75) were tested for the removal of two emerging contaminants - ibuprofen and naproxen. For each zeolite-rich rock, two ...

    Abstract Composites of two natural zeolites - clinoptilolite and phillipsite, and cationic surfactants (cetylpyridinium chloride and Arquad® 2HT-75) were tested for the removal of two emerging contaminants - ibuprofen and naproxen. For each zeolite-rich rock, two different modifications of the zeolitic surfaces were prepared (monolayer and bilayer surfactant coverage). The influence of the initial drug concentrations and contact time on adsorption of these drugs was followed in buffer solution. The Langmuir model showed the highest adsorption capacity for the composite characterized by a bilayered surfactant at the clinoptilolite surface: 19.7 mg/g and 16.1 mg/g for ibuprofen and naproxen, respectively. Also, to simulate real systems, drug adsorption isotherms were conducted in natural water (Grindstone creek water - Columbia, Missouri, USA) by using the best performing adsorbent; in this case, a slight decrease of drug adsorption was recorded. Kinetic runs were performed in distilled water as well as in the presence of ions such as sulfates and bicarbonates; also, in this case, the interfering agents defined an adsorption decrease for bilayer composites.
    MeSH term(s) Adsorption ; Hydrogen-Ion Concentration ; Ibuprofen ; Kinetics ; Missouri ; Naproxen ; Pharmaceutical Preparations ; Water ; Water Pollutants, Chemical ; Zeolites
    Chemical Substances Pharmaceutical Preparations ; Water Pollutants, Chemical ; Water (059QF0KO0R) ; Zeolites (1318-02-1) ; Naproxen (57Y76R9ATQ) ; Ibuprofen (WK2XYI10QM)
    Language English
    Publishing date 2021-02-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 184882-3
    ISSN 1095-8630 ; 0301-4797
    ISSN (online) 1095-8630
    ISSN 0301-4797
    DOI 10.1016/j.jenvman.2021.112168
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  10. Article ; Online: Exercise Intolerance and Oxygen Desaturation in Patients with Parkinson's Disease: Triggers for Respiratory Rehabilitation?

    Vitacca, Michele / Olivares, Adriana / Comini, Laura / Vezzadini, Giuliana / Langella, Annamaria / Luisa, Alberto / Petrolati, Anna / Frigo, Gianluigi / Paneroni, Mara

    International journal of environmental research and public health

    2021  Volume 18, Issue 23

    Abstract: The role that oxygen desaturation plays in exercise tolerance and its rehabilitative implications in patients with Parkinson's disease (PD) are unclear. We aimed to test exercise tolerance and oxygen saturation levels both during exercise and at night in ...

    Abstract The role that oxygen desaturation plays in exercise tolerance and its rehabilitative implications in patients with Parkinson's disease (PD) are unclear. We aimed to test exercise tolerance and oxygen saturation levels both during exercise and at night in PD patients to better define their rehabilitative needs. In clinically stable PD patients, undergoing inpatient rehabilitation, and in "ON" phase, we prospectively assessed clinical data, sleepiness, comorbidities, PD severity (Hoehn&Yahr, HY), motor function (ADLs, UPDRSII and UPDRSIII, Barthel Index, Functional Independence Measure), balance, spirometry, respiratory muscles (MIP/MEP), peak cough expiratory flow (PCEF), continuous night oxygen monitoring, and meters at 6MWT. Of 55 patients analyzed (28 with moderate-severe PD, HY ≥ 2.5), 37% and 23% showed moderate-severe impairment on UPDRSII and UPDRSIII, respectively; 96% had reduced exercise tolerance and severe respiratory muscles impairment (MIP/MEP < 45% pred.); 21.8% showed desaturations during exercise; and 12.7% showed nocturnal desaturations. At multiple regression, low exercise tolerance and low mean nocturnal and exercise-induced saturation correlated with several respiratory and motor function and disability indices (all
    MeSH term(s) Exercise Tolerance ; Humans ; Oxygen ; Oxygen Saturation ; Parkinson Disease ; Respiratory Muscles
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2021-11-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph182312298
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