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  1. Article: Surgery in Mercy Hospital.

    Larkin, J J

    The Chicago medical journal and examiner

    2023  Volume 42, Issue 1, Page(s) 52–54

    Language English
    Publishing date 2023-08-24
    Publishing country United States
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Laser treatment for glaucoma.

    Larkin, John

    Lancet (London, England)

    2020  Volume 396, Issue 10253, Page(s) 754

    MeSH term(s) Glaucoma ; Humans ; Laser Therapy ; Ocular Hypertension ; Ophthalmic Solutions ; Trabeculectomy
    Chemical Substances Ophthalmic Solutions
    Language English
    Publishing date 2020-09-12
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(20)31059-X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: To Browse, Click "Search".

    Larkin, John

    Scottish medical journal

    2019  Volume 64, Issue 2, Page(s) 41

    MeSH term(s) Biomedical Research ; Humans ; Online Systems ; Periodicals as Topic ; Publishing
    Language English
    Publishing date 2019-05-01
    Publishing country Scotland
    Document type Journal Article
    ZDB-ID 414085-0
    ISSN 2045-6441 ; 0036-9330
    ISSN (online) 2045-6441
    ISSN 0036-9330
    DOI 10.1177/0036933019848950
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Editorial.

    Larkin, John

    Scottish medical journal

    2019  Volume 64, Issue 1, Page(s) 1

    MeSH term(s) Humans ; Medicine ; Radiology ; Scotland
    Language English
    Publishing date 2019-02-19
    Publishing country Scotland
    Document type Editorial ; Introductory Journal Article
    ZDB-ID 414085-0
    ISSN 2045-6441 ; 0036-9330
    ISSN (online) 2045-6441
    ISSN 0036-9330
    DOI 10.1177/0036933019830890
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book ; Online: Systems Biology Approaches to Understanding the Cause and Treatment of Heart, Lung, Blood, and Sleep Disorders

    Larkin, Jennie / Winslow, Raimond L / Qasba, Pankaj

    2014  

    Abstract: Development of powerful new high- throughput technologies for probing the transcriptome, proteome and metabolome is driving the rapid acquisition of information on the function of molecular systems. The importance of these achievements cannot be ... ...

    Abstract Development of powerful new high- throughput technologies for probing the transcriptome, proteome and metabolome is driving the rapid acquisition of information on the function of molecular systems. The importance of these achievements cannot be understated - they have transformed the nature of both biology and medicine. Despite this dramatic progress, one of the greatest challenges that continues to confront modern biology is to understand how behavior at the level of genome, proteome and metabolome determines physiological function at the level of cell, tissue and organ in both health and disease. Because of the inherent complexity of biological systems, the development, analysis, and validation of integrative computational models based directly on experimental data is necessary to achieve this understanding.-

    This approach, known as systems biology, integrates computational and experimental approaches through iterative development of mathematical models and experimental validation and testing. The combination of these approaches allows for a mechanistic understanding of the function of complex biological systems in health and their dysfunction in disease. The National Heart, Lung, and Blood Institute (NHLBI) has recognized the importance of the systems biology approach for understanding normal physiology and perturbations associated with heart, lung, blood, and sleep diseases and disorders. In 2006, NHLBI announced the Exploratory Program in Systems Biology, followed in 2010 by the NHLBI Systems Biology Collaborations.-

    The goal of these programs is to support collaborative teams of investigators in using experimental and computational strategies to integrate the component parts of biological networks and pathways into computational models that are based firmly on and validated using experimental data. These validated models are then applied to gain insights into the mechanisms of altered system function in disease, to generate novel hypotheses regarding these mechanisms that can be tested experimentally, and to then use the results of experiments to refine the models. The purpose of this Research Topic is to present the range of innovative, new approaches being developed by investigators working in areas of systems biology that couple experimental and modeling studies to understand the cause and possible treatment of heart, lung, blood and sleep diseases and disorders.-
    Keywords Biotechnology ; Engineering (General). Civil engineering (General) ; Physiology ; Science (General)
    Size 1 electronic resource (180 p.)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT020090033
    ISBN 9782889192496 ; 2889192490
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  6. Article: A pyrrhic valedictory?

    Larkin, John

    Scottish medical journal

    2018  Volume 63, Issue 4, Page(s) 103

    Language English
    Publishing date 2018-11-01
    Publishing country Scotland
    Document type Editorial
    ZDB-ID 414085-0
    ISSN 2045-6441 ; 0036-9330
    ISSN (online) 2045-6441
    ISSN 0036-9330
    DOI 10.1177/0036933018811242
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Symptomatic melanoma CNS metastases in the TRICOTEL study.

    Schmitt, Andreas M / Larkin, James

    The Lancet. Oncology

    2022  Volume 23, Issue 11, Page(s) e481

    MeSH term(s) Humans ; Melanoma/pathology ; Central Nervous System Neoplasms/therapy ; Brain Neoplasms/therapy ; Brain Neoplasms/secondary ; Skin Neoplasms/pathology
    Language English
    Publishing date 2022-10-31
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2049730-1
    ISSN 1474-5488 ; 1470-2045
    ISSN (online) 1474-5488
    ISSN 1470-2045
    DOI 10.1016/S1470-2045(22)00566-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book ; Online: Coronavirus and Museum Resilience

    Larkin, Jamie

    Art Faculty Articles and Research

    Some Preliminary Observations

    2020  

    Abstract: The rapid spread of COVID-19 has led to virtually all UK museums being closed. The issue at hand is whether these temporary closures may become permanent, and which museums are likely to be the most resilient, both in the short and long term. These ... ...

    Abstract "The rapid spread of COVID-19 has led to virtually all UK museums being closed. The issue at hand is whether these temporary closures may become permanent, and which museums are likely to be the most resilient, both in the short and long term. These closures took place under very different circumstances to those we face today. Never before has the entire UK museum sector shutdown in this way, challenging the basic operating model of attracting visitors to physical sites. Here we consider what light our data might shed on the current situation."
    Keywords Museum Studies ; covid19
    Publishing date 2020-03-25T07:00:00Z
    Publisher Chapman University Digital Commons
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Personalized cancer care can't rely on molecular testing alone.

    Larkin, James / Beland, Chloe / Ramalingam, Sivatharshini / Lyon, Alexander R

    Nature

    2024  Volume 627, Issue 8002, Page(s) 38

    MeSH term(s) Humans ; Dissent and Disputes ; Molecular Diagnostic Techniques ; Neoplasms/classification ; Neoplasms/diagnosis ; Neoplasms/genetics ; Neoplasms/therapy ; Precision Medicine/methods ; Organ Specificity
    Language English
    Publishing date 2024-03-05
    Publishing country England
    Document type Letter
    ZDB-ID 120714-3
    ISSN 1476-4687 ; 0028-0836
    ISSN (online) 1476-4687
    ISSN 0028-0836
    DOI 10.1038/d41586-024-00631-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Editorial: Peritoneal dialysis: Recent advances and state of the art.

    Larkin, John / Barretti, Pasqual / de Moraes, Thyago Proença

    Frontiers in physiology

    2023  Volume 14, Page(s) 1185810

    Language English
    Publishing date 2023-04-12
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2564217-0
    ISSN 1664-042X
    ISSN 1664-042X
    DOI 10.3389/fphys.2023.1185810
    Database MEDical Literature Analysis and Retrieval System OnLINE

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