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  1. Article ; Online: Experimental and numerical analysis of the influence of intramedullary nail position on the cut-out phenomenon.

    Arias-Blanco, A / Marco, M / Giner, E / Larraínzar-Garijo, R / Miguélez, M H

    Computer methods and programs in biomedicine

    2023  Volume 240, Page(s) 107734

    Abstract: Background and objective: Proximal femur fractures, colloquially known as hip fractures, are a common pathology with increasing incidence in the last years due to the enhanced ageing population. Regarding the extracapsular fracture, the treatment for ... ...

    Abstract Background and objective: Proximal femur fractures, colloquially known as hip fractures, are a common pathology with increasing incidence in the last years due to the enhanced ageing population. Regarding the extracapsular fracture, the treatment for this pathology consists of a fixation of the fragments using an osteosynthesis device, mainly the intramedullary nail. This repairing method implies several complications, which may include the failure of the fixation device, frequently occurring due to the "cut-out" mechanism. The present work focuses on the study of how the position of the cephalic screw, which should be fixed during surgery, affects the cut-out risk. Through experimental tests and numerical models some variables that can be critical for the cut-out phenomenon are analysed.
    Methods: This study has been carried out through a numerical model based on the finite element method and experimental tests. The digital image correlation technique has been used in experimental tests to measure displacements on the femoral surface with the objective of numerical model validation. Some basic daily activities with different intramedullary nail positions have been analysed through the numerical model, considering variables that can induce the cut-out complication.
    Results: The results show how the intramedullary nail position clearly influences the cut-out risk, showing that displacements in the upper, anterior and posterior direction increase the cut-out risk, while displacement in the lower direction endangers the intramedullary nail itself. Thus, the centred position is the one which reduces the cut-out risk.
    Conclusions: This work supposes an improvement in the knowledge of the cut-out phenomenon thanks to the combination of experimental testing and validated numerical models. The effects of different intramedullary nail positions in the femoral head are studied, including a novelty variable as torque, which is critical for the structural integrity of the fixation. The main conclusion of the work is the determination of the central intramedullary nail position as the most favourable one for decreasing the cut-out risk.
    MeSH term(s) Humans ; Bone Nails ; Fracture Fixation, Intramedullary/methods ; Fracture Fixation, Internal ; Bone Screws ; Hip Fractures/surgery
    Language English
    Publishing date 2023-07-28
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 632564-6
    ISSN 1872-7565 ; 0169-2607
    ISSN (online) 1872-7565
    ISSN 0169-2607
    DOI 10.1016/j.cmpb.2023.107734
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  2. Article ; Online: Past and projected temporal trends in arthroscopic hip surgery in Spain between 1998 and 2018.

    Novoa-Parra, C D / Marín-Peña, O / Tey-Pons, M / Mas-Martínez, J / Franco-Ferrando, N / Larraínzar-Garijo, R

    Revista espanola de cirugia ortopedica y traumatologia

    2022  

    Abstract: Objective: Describe the population incidence of hip arthroscopy from 1998 to 2018 and to project the trends for the year 2030, as well as to describe the variations in the population incidence between the autonomous communities.: Material and method: ...

    Title translation Tendencias temporales pasadas y proyectadas en la cirugía artroscópica de cadera en España entre 1998 y 2018.
    Abstract Objective: Describe the population incidence of hip arthroscopy from 1998 to 2018 and to project the trends for the year 2030, as well as to describe the variations in the population incidence between the autonomous communities.
    Material and method: A retrospective review of the minimum basic data set from 1998 to 2018 was carried out. Temporal evolution was analyzed and the variables associated with the indication (age, sex, regions) were identified. For each region, the crude rate per 100,000 inhabitants was calculated. The 2019-2030 projection was made using linear regression.
    Results: In Spain between 1998 and 2018 a total of 10,663 arthroscopic hip surgeries were carried out. The population incidence in 1998 was 0.14 CAC per 100,000 inhabitants, while in 2018 it was 4.09. For the year 2030 an increase of 156.9% in the number of arthroscopic hip surgeries is expected (P<.001). On average, 57.7% of all procedures (95% CI 55.2-60.2) were done in men and the highest incidence was found in ages ≤44 years. The geographical variation was 81%, being up to 15.4 times the difference in incidence per 100,000 inhabitants between some regions.
    Conclusions: The number of hip arthroscopies in Spain has been increasing in the 1998-2018 period and this growing trend is expected to continue until 2030. In Spain, hip arthroscopic procedures are performed more frequently in male patients and in under 45 years old. The variability of the population incidence between the autonomous communities is high.
    Language Spanish
    Publishing date 2022-04-20
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 2417057-4
    ISSN 1988-8856 ; 1888-4415
    ISSN (online) 1988-8856
    ISSN 1888-4415
    DOI 10.1016/j.recot.2022.04.003
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  3. Article ; Online: [Translated article] Past and projected temporal trends in arthroscopic hip surgery in Spain between 1998 and 2018.

    Novoa-Parra, C D / Marín-Peña, O / Tey-Pons, M / Mas-Martínez, J / Franco-Ferrando, N / Larraínzar-Garijo, R

    Revista espanola de cirugia ortopedica y traumatologia

    2022  

    Abstract: Objective: Describe the population incidence of hip arthroscopy from 1998 to 2018 and to project the trends for the year 2030, as well as to describe the variations in the population incidence between the autonomous communities.: Material and method: ...

    Abstract Objective: Describe the population incidence of hip arthroscopy from 1998 to 2018 and to project the trends for the year 2030, as well as to describe the variations in the population incidence between the autonomous communities.
    Material and method: A retrospective review of the minimum basic data set from 1998 to 2018 was carried out. Temporal evolution was analysed and the variables associated with the indication (age, sex, regions) were identified. For each region, the crude rate per 100,000 inhabitants was calculated. The 2019-2030 projection was made using linear regression.
    Results: In Spain between 1998 and 2018 a total of 10,663 arthroscopic hip surgeries were carried out. The population incidence in 1998 was 0.14 CAC per 100,000 inhabitants, while in 2018 it was 4.09. For the year 2030 an increase of 156.9% in the number of arthroscopic hip surgeries is expected (p<.001). On average, 57.7% of all procedures (95% CI 55.2-60.2) were done in men and the highest incidence was found in ages≤44 years. The geographical variation was 81%, being up to 15.4 times the difference in incidence per 100,000 inhabitants between some regions.
    Conclusions: The number of hip arthroscopies in Spain has been increasing in the 1998-2018 period and this growing trend is expected to continue until 2030. In Spain, hip arthroscopic procedures are performed more frequently in male patients and in under 45 years old. The variability of the population incidence between the autonomous communities is high.
    Language Spanish
    Publishing date 2022-10-13
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 2417057-4
    ISSN 1988-8856 ; 1888-4415
    ISSN (online) 1988-8856
    ISSN 1888-4415
    DOI 10.1016/j.recot.2022.10.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Arthroscopic Volar Capsuloligamentous Reattachment and Reinforcement to Bone.

    Corella, Fernando / Ocampos, Montserrat / Laredo, Rafeal / Tabuenca, José / Larrainzar-Garijo, Ricardo

    Journal of wrist surgery

    2023  Volume 13, Issue 2, Page(s) 98–119

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2023-10-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2678060-4
    ISSN 2163-3924 ; 2163-3916
    ISSN (online) 2163-3924
    ISSN 2163-3916
    DOI 10.1055/s-0043-1775820
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Low-dose prophylaxis protocol for heterotopic ossification after hip preservation surgery in a sport participants cohort.

    Olivero, Matteo / Capurro, Bruno / Reis-Campos, Pedro / Aprato, Alessandro / Ayeni, Olufemi / Chawla, Anuj / Larrainzar Garijo, Ricardo / Marín-Peña, Oliver

    SICOT-J

    2023  Volume 9, Page(s) 27

    Abstract: Background: Heterotopic ossification (HO) is a well-known complication of arthroscopic and open surgical treatment of femoroacetabular impingement (FAI). Incidence of heterotopic ossification has been reported in the literature between 0% and 44% after ... ...

    Abstract Background: Heterotopic ossification (HO) is a well-known complication of arthroscopic and open surgical treatment of femoroacetabular impingement (FAI). Incidence of heterotopic ossification has been reported in the literature between 0% and 44% after hip arthroscopy and between 18.2% and 25% after anterior mini-open surgery. Currently, pharmacological prophylaxis with NSAIDs and selective COX-2 inhibitors are commonly used and their effectiveness is well documented in literature.
    Hypothesis: We hypothesized that the low-dose prophylaxis protocol with selective cox-2 inhibitors decreases the risk of heterotopic ossification in open or arthroscopic hip preservation surgery in athletes.
    Methods: This study is an analysis of prospectively gathered data on 98 sport participant patients who underwent arthroscopic or anterior mini-open treatment for FAI between April 2008 and April 2018. All the patients received postoperative oral prophylaxis with 60 mg etoricoxib once daily for two weeks. Post-operative X-rays were performed at 1, 3, and 12 months after surgery and reviewed by two orthopedic surgeons blinded to the type and side of surgery. HO were graded according to the Brooker classification. Descriptive statistics was used to analyze demographic data. Bivariate analysis was performed to analyze the association of HO with each of the following variables: type of surgery, physical activity, time of evolution of symptoms, age at surgery, and sex. Finally, a regression model analysis was performed to determine the presence of confounding effects between variables.
    Results: The study cohort was composed of 54 patients in the arthroscopic treatment group and 44 patients in the anterior mini-open group. HO was identified in 6 (13.6%) patients in the mini-open group. No HO was identified in the arthroscopic group. In the bivariate analysis, "type of surgery" was the only variable that showed a statistically significant association with HO (p = 0.007).
    Conclusion: Results of this study suggest that anterior mini-open treatment was characterized by a higher risk of HO development compared to hip arthroscopy for femoroacetabular impingement treatment regardless of pharmacological prophylaxis. The treatment regimen of 60 mg etoricoxib daily for two weeks was an effective prophylaxis for HO formation in sport participant patients compared with data available in the literature.
    Language English
    Publishing date 2023-09-05
    Publishing country France
    Document type Journal Article
    ZDB-ID 2832091-8
    ISSN 2426-8887
    ISSN 2426-8887
    DOI 10.1051/sicotj/2023024
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  6. Article ; Online: Complications of computer-assisted navigation in total knee replacement: retrospective cohort of eight hundred and seventy eight consecutive knees.

    Novoa-Parra, Carlos Daniel / Sanjuan-Cerveró, R / Franco-Ferrando, N / Larrainzar-Garijo, R / Egea-Castro, G / Lizaur-Utrilla, A

    International orthopaedics

    2020  Volume 44, Issue 12, Page(s) 2621–2626

    Abstract: Purpose: The main objective was to analyze the computer-assisted navigation (CAN)-specific complications that forced to switch to conventional procedure in primary total knee replacement (TKR). The secondary objective was to determine the influence of ... ...

    Abstract Purpose: The main objective was to analyze the computer-assisted navigation (CAN)-specific complications that forced to switch to conventional procedure in primary total knee replacement (TKR). The secondary objective was to determine the influence of those complications on TKR short-term survival.
    Methods: Retrospective study of 878 primary TKR in 753 patients. Two consecutive versions of the OrthoPilot navigation system (Braun Aesculap, Germany) were used during the study time. Specific complications of CAN were defined as those due to the instrumentation (hardware or software failures), which were classified in one of two categories according to whether they occurred during the registration or tracking process.
    Results: There were 20 (2.3%) complications related to the navigation system use that forced to switch to conventional surgery: in 11 (1.2%) knees due to loosening of the tracking pins, and in the other nine (1.0%) there were information system failures. There was a trend for a higher conversion rate to conventional surgery with the use of the first version of the software. There were no fractures, infections, or nerve injuries at the pin site. We found no differences in the distribution of baseline variables among those with or without conversion to conventional surgery. There was no significant difference (p = 0.488) in the two year survival between patients with or without conversion.
    Conclusion: CAN for primary TKR is a safe method with few specific complications that forced to switch from the navigated to the conventional procedure. Conversion to conventional surgery did not affect the short-term survival of TKR.
    MeSH term(s) Arthroplasty, Replacement, Knee/adverse effects ; Bone Nails ; Germany ; Humans ; Retrospective Studies ; Surgery, Computer-Assisted
    Language English
    Publishing date 2020-06-25
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 80384-4
    ISSN 1432-5195 ; 0341-2695
    ISSN (online) 1432-5195
    ISSN 0341-2695
    DOI 10.1007/s00264-020-04675-x
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  7. Article: Importance of the gender and preoperative knee sagittal alignment to avoid unnecessary tibial resection in TKR.

    Novoa-Parra, Carlos Daniel / Sanjuan-Cerveró, R / de la Iglesia, N H / Franco-Ferrando, N / Larrainzar-Garijo, R / Lizaur-Utrilla, A

    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie

    2020  Volume 31, Issue 2, Page(s) 333–340

    Abstract: Background: Standard resections according to the TKR manufacturers can lead to unnecessary bone resections in some patients. The objective of this study was to determine in which patients is recommended to perform a minimal tibial resection (MTR) that ... ...

    Abstract Background: Standard resections according to the TKR manufacturers can lead to unnecessary bone resections in some patients. The objective of this study was to determine in which patients is recommended to perform a minimal tibial resection (MTR) that could restore the joint line height (JLH).
    Methods: Navigation records of 108 consecutive posterior cruciate-substituting TKR performed by one surgeon were analyzed. Optimal tibial resection depth to restore the JLH (0 mm) was calculated by an algorithm. Postoperatively, the knees were distributed in two groups: those in which a MTR (depth ≤ 8 mm) would have been enough to restore the JLH and those in which a standard resection depth would have been necessary. ROC curves and Youden index were used to determine the cutoff point of the coronal and sagittal mechanical axis that predicted a MTR restoring the JLH. Multivariate analysis was used to identify independent factors associated with requiring an MTR.
    Results: A MTR could be required in 20 (18.5%) knees. In the ROC curve analyses, the cutoff points that best discriminated between minimal and standard tibial resection was  ≤ 3° of varus and  < 2° of flexion preoperative deformity. Multivariate analysis showed that female gender and preoperative flexion < 2° were significant predictors of requiring a MTR to restore JLH.
    Conclusion: A MTR with the JLH restoration could be possible in female patients with a preoperative sagittal deformity less than 2° of flexion. Preoperative coronal alignment had no influence to discriminate when a MTR is required.
    MeSH term(s) Arthroplasty, Replacement, Knee ; Female ; Humans ; Knee/surgery ; Knee Joint/surgery ; Knee Prosthesis ; Osteoarthritis, Knee/surgery ; Tibia/surgery
    Language English
    Publishing date 2020-09-04
    Publishing country France
    Document type Journal Article
    ZDB-ID 1231084-0
    ISSN 1432-1068 ; 1633-8065 ; 0948-4817 ; 0940-3264
    ISSN (online) 1432-1068
    ISSN 1633-8065 ; 0948-4817 ; 0940-3264
    DOI 10.1007/s00590-020-02773-5
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  8. Article: Arthroscopic Volar Capsuloligamentous Reattachment and Reinforcement to Bone

    Corella, Fernando / Ocampos, Montserrat / Laredo, Rafeal / Tabuenca, José / Larrainzar-Garijo, Ricardo

    Journal of Wrist Surgery

    2023  Volume 13, Issue 02, Page(s) 98–119

    Abstract: Background: Injuries of the volar ligaments of the wrist are not uncommon, but their arthroscopic treatment presents a significant challenge. The objective of this paper is to introduce a technique for reattaching (in acute injuries) or reinforcing (in ... ...

    Abstract Background: Injuries of the volar ligaments of the wrist are not uncommon, but their arthroscopic treatment presents a significant challenge. The objective of this paper is to introduce a technique for reattaching (in acute injuries) or reinforcing (in chronic injuries) various volar wrist ligaments to the bone, using standard wrist arthroscopic dorsal and volar portals.
    Methods: There are three common steps for all the arthroscopic volar capsuloligamentous reattachments or reinforcements Step 1 – Volar Portal Establishment: volar radial, volar ulnar and volar central portals are used depending on which structure needs to be reattached or reinforced. Step 2 – Anchor Placement: the anchor is positioned at the site where the ligament has been detached. Step 3 – Capsuloligamentous Suture and Knotting: a knot pusher is introduced inside the joint from the dorsal portal and advanced inside the volar portal where the threads of the anchor are located. The knot pusher is loaded with the threads and retrieved to the dorsal portal. A 16G Abbocath, loaded with a loop is used to pierce the volar ligaments. The loop of the Abbocath is captured from the dorsal portal and loaded with the threads. Both threads are taken to the volar portal and knotted after releasing the traction. This way the knot is placed out of the wrist and the ligaments are reattached or reinforced to the bone.
    Result: This technique has been used to reinforce and reattach the scapholunate and lunotriquetral ligaments and to reattach the radiocarpal ligaments and the Poirier space. Since this procedure has been performed in various conditions and in conjunction with other ligament treatments (such as perilunate injuries, carpal bone fractures, distal radius fractures, and reinforcement or reattachment of the dorsal portions of intrinsic ligaments), specific results are not presented.
    Conclusions: The described technique enables the reattachment and reinforcement of most volar ligaments to the bone using standard wrist arthroscopic portals. It can be performed in conjunction with the treatment of the dorsal portion of intrinsic ligaments or other wrist injuries.
    Keywords volar capsuloligamentous suture ; wrist arthroscopy ; perilunate injuries ; scapholunate injury ; lunotriquetral injury
    Language English
    Publishing date 2023-10-13
    Publisher Thieme Medical Publishers, Inc.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2678060-4
    ISSN 2163-3924 ; 2163-3916 ; 2163-3924
    ISSN (online) 2163-3924
    ISSN 2163-3916 ; 2163-3924
    DOI 10.1055/s-0043-1775820
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  9. Article ; Online: Experimental validation of finite elements model in hip fracture and its clinical applicability.

    Larrainzar-Garijo, R / Caeiro, J R / Marco, M / Giner, E / Miguélez, M H

    Revista espanola de cirugia ortopedica y traumatologia

    2018  Volume 63, Issue 2, Page(s) 146–154

    Abstract: Fracture of the proximal extremity of the femur is the subject of research interest. The complexity of the bone framework and the structural inefficiency associated with ageing leave many variables yet to be understood from an experimental perspective. ... ...

    Title translation Validación experimental de un modelo de análisis de elementos finitos en fractura de cadera y su aplicabilidad clínica.
    Abstract Fracture of the proximal extremity of the femur is the subject of research interest. The complexity of the bone framework and the structural inefficiency associated with ageing leave many variables yet to be understood from an experimental perspective. However, there is no clearly defined structural and biomechanical research model for hip fracture. The hypothesis of this paper is that it is possible to create a computational experimentation model that characterises the bone of the proximal extremity of the femur as a heterogeneous material from directly translating the mechanical parameters obtained from anatomical experimentation specimens.
    Material and method: An experimental paper comparing real experimentation on cadavers and a numerical model based on finite element analysis (FEA). The variables uses were: the start point of the fracture, propagation of the fracture, progressive load and maximum load until fracture. The real mechanical parameters obtained from the anatomical specimens were translated to the computational model based on the relationship between the Hounsfield units of the high resolution CAT scan and the bone mineral density of each virtual element, whereas the propagation of the fracture was modelled by the research team's own computational design, reducing the mechanical properties of the damaged elements as the fracture line advanced.
    Results: The computational model was able to determine the start point of the fracture, with a slight tendency towards anatomical medialisation of this point compared to what happened experimentally. The degree of correlation was very high on comparing the real value of progressive deformation of the samples compared to that obtained by the computational model. Over 32 points analysed, a slope of 1.03 in lineal regression was obtained, with a relative error between the deformations of 16% and a Pearson's coefficient of R
    Conclusion: The FEA computational model developed by this multi-disciplinary research team could be considered, as a whole, a complete FEA model of the proximal extremity of the femur with future clinical applicability since it was able to simulate and imitate the biomechanical behaviour of human femurs contrasted with a traditional experimental model made from anatomical specimens. On this basis, qualitative and quantitative interactions can be assessed which consolidate it as a powerful computational experimentation test bench for the human proximal femur.
    MeSH term(s) Aged ; Cadaver ; Female ; Finite Element Analysis ; Hip Fractures/pathology ; Humans ; Male ; Models, Theoretical
    Language Spanish
    Publishing date 2018-10-22
    Document type Comparative Study ; Journal Article ; Validation Study
    ISSN 2173-576X
    ISSN (online) 2173-576X
    DOI 10.1016/j.recot.2018.05.006
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  10. Article ; Online: Survival analysis and influence of the surgical aggression of a cohort of orthopedic and trauma patients in a non-controlled spread COVID-19 scenario.

    Corella, Fernando / Rosales, Roberto S / Guzman Domenech, David / Cañones Martín, Miguel / Larrainzar-Garijo, Ricardo

    BMC musculoskeletal disorders

    2021  Volume 22, Issue 1, Page(s) 594

    Abstract: Background: Determining the infection rate and mortality probability in healthy patients who have undergone orthopedic and trauma surgeries (OTS) during a period of uncontrolled COVID-19 transmission may help to inform preparations for future waves. ... ...

    Abstract Background: Determining the infection rate and mortality probability in healthy patients who have undergone orthopedic and trauma surgeries (OTS) during a period of uncontrolled COVID-19 transmission may help to inform preparations for future waves. This study performed a survival analysis in a cohort of non-infected OTS patients and determined the effect of COVID-19 on mortality.
    Methods: This observational study included 184 patients who underwent OTS in the month before surgical activities ceased and before the implementation of special measures. Four groups of surgery (GS) were established based on the location of the surgery and the grade of inflammation produced. Crude risk of infection and infection rates were assessed. Survival and failure functions by GS were analyzed. Comparison of the Kaplan-Meier survival curves by GS was assessed. Cox regression and Fine-Gray models were used to determine the effect of different confounders on mortality.
    Results: The crude risk of COVID-19 diagnosis was 14.13% (95% CI: 9.83-19.90%). The total incidence rate was 2.67 (1000 person-days, 95% CI: 1.74-3.91). At the end of follow-up, there was a 94.42% chance of surviving 76 days or more after OTS. The differences in K-M survivor curves by GS indicated that GS 4 presented a lower survival function (Mantel-Cox test, p = 0.024; Wilcoxon-Breslow test, p = 0.044; Tarone-Ware test, p = 0.032). One of the best models to determine the association with mortality was the age-adjusted model for GS, high blood pressure, and respiratory history, with a hazard ratio of 1.112 in Cox regression analysis (95% CI: 1.005-1.230) and a sub hazard ratio of 1.111 (95% CI: 1.046-1.177) in Fine-Gray regression analysis for competitive risk.
    Conclusions: The infection risk after OTS was similar to that of the general population in a community transmission area; the grade of surgical aggression did not influence this rate. The survival probability was extremely high if patients had not previously been infected. With higher grades of surgical aggression, the risk of mortality was higher in OTS patients. Adjusting for age and other confounders (e.g., GS, high blood pressure and respiratory history) was associated with higher mortality rates.
    MeSH term(s) Aggression ; COVID-19 ; COVID-19 Testing ; Humans ; SARS-CoV-2 ; Survival Analysis
    Language English
    Publishing date 2021-06-28
    Publishing country England
    Document type Journal Article ; Observational Study
    ISSN 1471-2474
    ISSN (online) 1471-2474
    DOI 10.1186/s12891-021-04303-8
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