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  1. Article ; Online: Should liver metastases of pancreatic adenocarcinoma be resected?

    Muzzolini, Milena / Lupinacci, Renato / Bachet, Jean-Baptiste / Lassoued, Donia / Sauvanet, Alain / Gaujoux, Sébastien

    Journal of visceral surgery

    2024  Volume 161, Issue 2, Page(s) 129–140

    MeSH term(s) Humans ; Pancreatic Neoplasms/surgery ; Pancreatic Neoplasms/pathology ; Pancreatic Neoplasms/secondary ; Liver Neoplasms/secondary ; Liver Neoplasms/surgery ; Adenocarcinoma/surgery ; Adenocarcinoma/secondary ; Adenocarcinoma/pathology ; Hepatectomy/methods
    Language English
    Publishing date 2024-01-22
    Publishing country France
    Document type Editorial ; Journal Article
    ISSN 1878-7886
    ISSN (online) 1878-7886
    DOI 10.1016/j.jviscsurg.2023.12.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Bortezomib improved the joint manifestations of rheumatoid arthritis in three patients.

    Lassoued, Slim / Moyano, Chantal / Beldjerd, Mounir / Pauly, Pierre / Lassoued, Donia / Billey, Thierry

    Joint bone spine

    2019  Volume 86, Issue 3, Page(s) 381–382

    Abstract: The proteasome inhibitor bortezomib has been proven effective in the treatment of multiple myeloma. We report on 3 patients with rheumatoid arthritis and multiple myeloma in whom bortezomib therapy was associated with improvements in the joint ... ...

    Abstract The proteasome inhibitor bortezomib has been proven effective in the treatment of multiple myeloma. We report on 3 patients with rheumatoid arthritis and multiple myeloma in whom bortezomib therapy was associated with improvements in the joint manifestations. The contribution to this effect of the concomitant glucocorticoid therapy is discussed.
    MeSH term(s) Aged ; Arthritis, Rheumatoid/diagnosis ; Arthritis, Rheumatoid/drug therapy ; Arthritis, Rheumatoid/epidemiology ; Bortezomib/administration & dosage ; Comorbidity ; Dose-Response Relationship, Drug ; Drug Administration Schedule ; Female ; Humans ; Male ; Middle Aged ; Multiple Myeloma/diagnosis ; Multiple Myeloma/drug therapy ; Multiple Myeloma/epidemiology ; Pain Measurement ; Prognosis ; Proteasome Inhibitors/administration & dosage ; Range of Motion, Articular/drug effects ; Sampling Studies ; Treatment Outcome
    Chemical Substances Proteasome Inhibitors ; Bortezomib (69G8BD63PP)
    Language English
    Publishing date 2019-02-06
    Publishing country France
    Document type Journal Article
    ZDB-ID 2020487-5
    ISSN 1778-7254 ; 1297-319X
    ISSN (online) 1778-7254
    ISSN 1297-319X
    DOI 10.1016/j.jbspin.2019.01.019
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4590: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: FOLFIRI in advanced platinum-resistant/refractory small-cell lung cancer: a retrospective study.

    Roussel-Simonin, Cyril / Gougis, Paul / Lassoued, Donia / Vozy, Aurore / Veyri, Marianne / Morardet, Laetitia / Wassermann, Johanna / Foka Tichoue, Hervé / Jaffrelot, Loïc / Hassani, Lamia / Perrier, Alexandre / Bergeret, Sebastien / Taillade, Laurent / Spano, Jean-Philippe / Campedel, Luca / Abbar, Baptiste

    Acta oncologica (Stockholm, Sweden)

    2023  Volume 62, Issue 6, Page(s) 579–586

    Abstract: Background: Small-cell lung cancer (SCLC) accounts for approximately 15% of lung cancer and is associated with poor prognosis. In platinum-refractory or -resistant SCLC patients, few treatment options are available. Topotecan is one of the standards of ... ...

    Abstract Background: Small-cell lung cancer (SCLC) accounts for approximately 15% of lung cancer and is associated with poor prognosis. In platinum-refractory or -resistant SCLC patients, few treatment options are available. Topotecan is one of the standards of care for these patients, however, due to its high toxicity, several different approaches are employed. FOLFIRI (folinate, 5-fluorouracil and irinotecan) is a chemotherapy regimen used in digestive neuroendocrine carcinoma, which shares pathological similarities with SCLC. In this retrospective study, we evaluated the efficacy and safety of FOLFIRI in patients with platinum-resistant/refractory SCLC.
    Methods: Medical records from all consecutive SCLC patients treated with FOLFIRI in a French University Hospital from 2013 to 2021 were analyzed retrospectively. The primary endpoint was the objective response rate according to RECIST v1.1 or EORTC criteria (ORR); secondary endpoints included duration of response, disease control rate, progression-free survival (PFS), overall survival (OS) and safety profile.
    Results: Thirty-four patients with metastatic platinum-resistant (
    Conclusion: FOLFIRI showed some activity for platinum-resistant/refractory SCLC in terms of overall response and had an acceptable safety profile. However, caution is needed in interpreting this result. FOLFIRI could represent a potential new treatment for platinum-resistant/refractory SCLC patients. Further prospective studies are needed to assess the benefits of this chemotherapy regimen.HIGHLIGHTSFOLFIRI showed some activity for platinum-resistant/refractory SCLC in terms of overall response.FOLFIRI was well-tolerated in platinum resistant/refractory SLCL patients.FOLFIRI could represent a potential new treatment for SCLC, prospective studies are needed.
    MeSH term(s) Humans ; Retrospective Studies ; Platinum/therapeutic use ; Camptothecin/adverse effects ; Treatment Outcome ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Small Cell Lung Carcinoma/drug therapy ; Lung Neoplasms
    Chemical Substances Platinum (49DFR088MY) ; Camptothecin (XT3Z54Z28A)
    Language English
    Publishing date 2023-06-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 896449-x
    ISSN 1651-226X ; 0349-652X ; 0284-186X ; 1100-1704
    ISSN (online) 1651-226X
    ISSN 0349-652X ; 0284-186X ; 1100-1704
    DOI 10.1080/0284186X.2023.2216339
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6348: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Active Monitoring of a Humeral Osteoblastoma in a 52-Year-Old Male: A Case Report.

    Bouchet, Juliette / Lassoued, Donia / Boussier, Nathalie / Birebent, Jordan / Oustric, Stephane / Rouge-Bugat, Marie-Eve

    World journal of oncology

    2015  Volume 6, Issue 2, Page(s) 329–331

    Abstract: An osteoblastoma is an uncommon benign but painful tumor, typically found on the axial skeleton or on long bones in the case of young patients. Some cases of humeral osteoblastomas have been described in literature but not in men older than 30. We report ...

    Abstract An osteoblastoma is an uncommon benign but painful tumor, typically found on the axial skeleton or on long bones in the case of young patients. Some cases of humeral osteoblastomas have been described in literature but not in men older than 30. We report the case of a painless bone tumor on the humerus of a 52-year-old patient. The CT scan shows a 30 mm hypodense lacunar formation, surrounded by thickened cortical bone resembling an osteoid osteoma. The anatomopathological and immunohistological analyses support the thesis of an osteoblastoma. A course of radiological monitoring without surgical resection was adopted. This unusual case introduces the possibility of carrying out a differential diagnosis with an osteosarcoma and raises the question of the treatment that should be adopted.
    Language English
    Publishing date 2015-04-12
    Publishing country Canada
    Document type Case Reports
    ZDB-ID 2548989-6
    ISSN 1920-454X ; 1920-4531
    ISSN (online) 1920-454X
    ISSN 1920-4531
    DOI 10.14740/wjon871w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Guideline sheets on the side effects of anticancer drugs are useful for general practitioners.

    Rouge-Bugat, Marie-Eve / Lassoued, Donia / Bacrie, Joy / Boussier, Nathalie / Delord, Jean-Pierre / Oustric, Stéphane / Bauvin, Eric / Lapeyre-Mestre, Maryse / Bertucci, François / Grosclaude, Pascale

    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

    2015  Volume 23, Issue 12, Page(s) 3473–3480

    Abstract: Purpose: General practitioners (GPs) are more and more involved in the treatment of cancer patients but feel not informed enough about anticancer treatments and associated side effects. Better communication with treatment centers is needed. We ... ...

    Abstract Purpose: General practitioners (GPs) are more and more involved in the treatment of cancer patients but feel not informed enough about anticancer treatments and associated side effects. Better communication with treatment centers is needed. We hypothesized that information sheets could improve communication.
    Methods: This prospective, multicentric, and interventionist study aimed at implementing and assessing therapeutic sheets describing the side effects of anticancer drugs used for digestive and gynecological cancers and their recommended management. GPs' phone interviews were done through three successive phases and two independent cohorts. The first phase (T1; 242 GPs with one patient recently treated) listed their expectations, the second (T2; 158 GPs with one patient beginning treatment) assessed the GPs' opinion regarding the sheets, and the third (T3; responder GPs 4 months after the start of T2) assessed their usefulness in practice.
    Results: In T1, 94% of GPs declared their need of having information sheets, notably for the management of side effects. Thirty-one one-page sheets were created. In T2, 83.5% gave a favorable opinion about sheets and 80% envisaged their use in the case of side effect. In T3, 56% of GPs whose patient had experienced a side effect had used successfully the sheets for its management, and 21% of patients with side effect were hospitalized. A strong correlation existed between the use of the sheet by GPs and the hospitalization (OR 7.35 in the case of no use vs use).
    Conclusion: The guideline sheets represent a simple and low-cost solution to help GPs managing drugs' side effects and perhaps decrease the rate of unplanned hospitalizations.
    MeSH term(s) Adult ; Aged ; Antineoplastic Agents/adverse effects ; Antineoplastic Agents/therapeutic use ; Communication ; Female ; General Practitioners/organization & administration ; General Practitioners/statistics & numerical data ; Humans ; Male ; Middle Aged ; Neoplasms/drug therapy ; Neoplasms/epidemiology ; Physician-Patient Relations ; Pilot Projects ; Practice Guidelines as Topic ; Prospective Studies
    Chemical Substances Antineoplastic Agents
    Language English
    Publishing date 2015-12
    Publishing country Germany
    Document type Clinical Trial ; Journal Article ; Multicenter Study
    ZDB-ID 1134446-5
    ISSN 1433-7339 ; 0941-4355
    ISSN (online) 1433-7339
    ISSN 0941-4355
    DOI 10.1007/s00520-015-2705-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3697: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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