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  1. Article: Use of Botulinum Toxin A to Manage Hamstring-Induced Flexion Contracture Following Total Knee Arthroplasty: A Case Series.

    Cheesman, Quincy T / Ponzio, Danielle Y / Thalody, Hope E / Lau, Vincent W / Post, Zachary D / Ong, Alvin

    Cureus

    2024  Volume 16, Issue 1, Page(s) e53113

    Abstract: Introduction Flexion contractures following total knee arthroplasty (TKA) greatly affect patient function and satisfaction. Botulinum toxin A (BTX) has been described in the literature as a means of addressing post-operative flexion contractures due to ... ...

    Abstract Introduction Flexion contractures following total knee arthroplasty (TKA) greatly affect patient function and satisfaction. Botulinum toxin A (BTX) has been described in the literature as a means of addressing post-operative flexion contractures due to hamstring muscle rigidity. Methods We retrospectively report a case series of eight patients with range of motion (ROM) who developed a flexion contracture status post-TKA and were managed with the use of physical therapy, diagnostic hamstring lidocaine injections, and therapeutic hamstring BTX injections. Results All patients had an improvement in extension ROM following diagnostic lidocaine hamstring injections and were therefore considered candidates for therapeutic hamstring BTX injections. Prior to therapeutic hamstring BTX injections, patients had an average flexion contracture of 19° (range: 15°-22°). All patients had an improvement in extension ROM two to four weeks following the therapeutic hamstring BTX injection, with an average improvement in ROM of 7° (range: 2°-19°). At the final follow-up, all patients continued to sustain an improvement in extension ROM with an average deficit of 9° (range: 0°-17°). Conclusion Our case series highlights the use of diagnostic hamstring lidocaine injections to confirm hamstring rigidity as an etiology for flexion contracture following TKA. In addition, we showed a persistent improvement in flexion contracture for all patients after hamstring BTX injections. Therefore, when the appropriate patient is selected, BTX may provide an additional treatment option for a flexion contracture following TKA.
    Language English
    Publishing date 2024-01-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.53113
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Homonuclear Mixed-Valent Cobalt Imidazolate Framework for Oxygen-Evolution Electrocatalysis.

    Flügel, Erik A / Lau, Vincent W-H / Schlomberg, Hendrik / Glaum, Robert / Lotsch, Bettina V

    Chemistry (Weinheim an der Bergstrasse, Germany)

    2016  Volume 22, Issue 11, Page(s) 3676–3680

    Abstract: Herein, the synthesis and characterization of the first mixed-valent, purely cobalt-based zeolitic imidazolate framework, Co(II)3Co(III)2(C3H3N2)12 is presented. The material adopts the cubic garnet-type structure and combines high thermal stability of ... ...

    Abstract Herein, the synthesis and characterization of the first mixed-valent, purely cobalt-based zeolitic imidazolate framework, Co(II)3Co(III)2(C3H3N2)12 is presented. The material adopts the cubic garnet-type structure and combines high thermal stability of up to 350 °C with excellent chemical stability. Electrochemical characterization showed that the cobalt centres are redox active and efficiently support oxygen evolution, thus rendering this framework a potential candidate for single-site heterogeneous catalysis based on earth-abundant elements.
    Language English
    Publishing date 2016-03-07
    Publishing country Germany
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1478547-x
    ISSN 1521-3765 ; 0947-6539
    ISSN (online) 1521-3765
    ISSN 0947-6539
    DOI 10.1002/chem.201504151
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Photocatalytic hydrogen production using polymeric carbon nitride with a hydrogenase and a bioinspired synthetic Ni catalyst.

    Caputo, Christine A / Gross, Manuela A / Lau, Vincent W / Cavazza, Christine / Lotsch, Bettina V / Reisner, Erwin

    Angewandte Chemie (International ed. in English)

    2014  Volume 53, Issue 43, Page(s) 11538–11542

    Abstract: Solar-light-driven H2 production in water with a [NiFeSe]-hydrogenase (H2ase) and a bioinspired synthetic nickel catalyst (NiP) in combination with a heptazine carbon nitride polymer, melon (CN(x)), is reported. The semibiological and purely synthetic ... ...

    Abstract Solar-light-driven H2 production in water with a [NiFeSe]-hydrogenase (H2ase) and a bioinspired synthetic nickel catalyst (NiP) in combination with a heptazine carbon nitride polymer, melon (CN(x)), is reported. The semibiological and purely synthetic systems show catalytic activity during solar light irradiation with turnover numbers (TONs) of more than 50,000 mol H2(mol H2ase)(-1) and approximately 155 mol H2 (mol NiP)(-1) in redox-mediator-free aqueous solution at pH 6 and 4.5, respectively. Both systems maintained a reduced photoactivity under UV-free solar light irradiation (λ>420 nm).
    MeSH term(s) Catalysis ; Hydrogen/chemistry ; Nickel/chemistry ; Nitriles/chemistry ; Photochemistry
    Chemical Substances Nitriles ; cyanogen (534Q0F66RK) ; Nickel (7OV03QG267) ; Hydrogen (7YNJ3PO35Z)
    Language English
    Publishing date 2014-09-09
    Publishing country Germany
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2011836-3
    ISSN 1521-3773 ; 1433-7851
    ISSN (online) 1521-3773
    ISSN 1433-7851
    DOI 10.1002/anie.201406811
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Photocatalytic Hydrogen Production using Polymeric Carbon Nitride with a Hydrogenase and a Bioinspired Synthetic Ni Catalyst.

    Caputo, Christine A / Gross, Manuela A / Lau, Vincent W / Cavazza, Christine / Lotsch, Bettina V / Reisner, Erwin

    Angewandte Chemie (Weinheim an der Bergstrasse, Germany)

    2014  Volume 126, Issue 43, Page(s) 11722–11726

    Abstract: Solar-light-driven ... ...

    Abstract Solar-light-driven H
    Language English
    Publishing date 2014-09-09
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 506609-8
    ISSN 1521-3757 ; 0044-8249 ; 0932-2140
    ISSN (online) 1521-3757
    ISSN 0044-8249 ; 0932-2140
    DOI 10.1002/ange.201406811
    Database MEDical Literature Analysis and Retrieval System OnLINE

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