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  1. Book ; Online: Principles of Decoration in the Roman World

    Haug, Annette / Taylor Lauritsen, M.

    2021  

    Keywords Classical Greek & Roman archaeology ; Decoration ; Roman art and architecture ; Pompeii
    Size 1 electronic resource (194 pages)
    Publisher De Gruyter
    Publishing place Berlin/Boston
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021050966
    ISBN 9783110732214 ; 3110732211
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online: Materiality in Roman Art and Architecture

    Haug, Annette / Hielscher, Adrian / Taylor Lauritsen, Michael

    2021  

    Keywords Classical history / classical civilisation ; Classical Greek & Roman archaeology ; Materiality ; Roman architecture ; decor and decoration ; object design
    Size 1 electronic resource (286 pages)
    Publisher De Gruyter
    Publishing place Berlin/Boston
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021289801
    ISBN 9783110764765 ; 3110764768
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article ; Online: The completeness of routine registration of the counterpart in deliberate interpersonal violence in an urban emergency department.

    Faergemann, Christian / Lauritsen, Jens Martin

    Journal of forensic and legal medicine

    2024  Volume 102, Page(s) 102640

    Abstract: Most studies of violence from the health care system lack reliable information about the counterpart, which is important for distinguishing between different types of violence. Since 2014, the emergency department at Odense University Hospital in Denmark ...

    Abstract Most studies of violence from the health care system lack reliable information about the counterpart, which is important for distinguishing between different types of violence. Since 2014, the emergency department at Odense University Hospital in Denmark has routinely registered information about the counterpart. The purpose of this study was to evaluate the completeness of registering information about the counterpart during routine registration of victims of interpersonal violence in the emergency department. We included 11,200 victims treated at the emergency department 2014-2021. Using the patient registration data, we estimated the proportion of missing information on the counterpart, stratified by age group and gender of the victim as well as type of incident and severity of injury. Information about the counterpart was registered in 91.5 % of all cases. In 43.1 % (CI: 42.2-44.0) of the cases, the counterpart was unknown to the victim, in 24.3 % (CI: 23.5-25.1) the counterpart was an acquaintance, in 10.5 % (CI: 10.0-11.1) the counterpart was a partner, and in 4.2 % (CI: 3.8-4.5) the counterpart was another family member. The proportion of cases with no information about the counterpart varied with gender, age group, time of violence, place of violence, weapon use, and severity of injury. Half of the victims injured with firearms (46.2 %, CI: 30.1-62.8) and one-fourth of the victims injured with knives (25.9 %, CI: 21.9-30.2) did not reveal information about the counterpart. The majority of the victims revealed information about the counterpart, making it possible to analyse different types of violence separately.
    MeSH term(s) Humans ; Violence ; Emergency Service, Hospital ; Firearms ; Weapons ; Wounds and Injuries/epidemiology
    Language English
    Publishing date 2024-01-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 2268721-X
    ISSN 1878-7487 ; 1752-928X
    ISSN (online) 1878-7487
    ISSN 1752-928X
    DOI 10.1016/j.jflm.2024.102640
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Stochastic cellular automaton model of culture formation.

    Klausen, Frederik Ravn / Lauritsen, Asbjørn Bækgaard

    Physical review. E

    2023  Volume 108, Issue 5-1, Page(s) 54307

    Abstract: We introduce a stochastic cellular automaton as a model for culture and border formation. The model can be conceptualized as a game where the expansion rate of cultures is quantified in terms of their area and perimeter in such a way that approximately ... ...

    Abstract We introduce a stochastic cellular automaton as a model for culture and border formation. The model can be conceptualized as a game where the expansion rate of cultures is quantified in terms of their area and perimeter in such a way that approximately geometrically round cultures get a competitive advantage. We first analyze the model with periodic boundary conditions, where we study how the model can end up in a fixed state, i.e., freezes. Then we implement the model on the European geography with mountains and rivers. We see how the model reproduces some qualitative features of European culture formation, namely, that rivers and mountains are more frequently borders between cultures, mountainous regions tend to have higher cultural diversity, and the central European plain has less clear cultural borders.
    Language English
    Publishing date 2023-12-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2844562-4
    ISSN 2470-0053 ; 2470-0045
    ISSN (online) 2470-0053
    ISSN 2470-0045
    DOI 10.1103/PhysRevE.108.054307
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The systemic immune response in Parkinson's disease: focus on the peripheral immune component.

    Lauritsen, Johanne / Romero-Ramos, Marina

    Trends in neurosciences

    2023  Volume 46, Issue 10, Page(s) 863–878

    Abstract: During Parkinson's disease (PD), both the central nervous system (CNS) and peripheral nervous system (PNS) are affected. In parallel, innate immune cells respond early to neuronal changes and alpha-synuclein (α-syn) pathology. Moreover, some of the ... ...

    Abstract During Parkinson's disease (PD), both the central nervous system (CNS) and peripheral nervous system (PNS) are affected. In parallel, innate immune cells respond early to neuronal changes and alpha-synuclein (α-syn) pathology. Moreover, some of the affected neuronal groups innervate organs with a relevant role in immunity. Consequently, not only microglia, but also peripheral immune cells are altered, resulting in a systemic immune response. Innate and adaptive immune cells may participate in the neurodegenerative process by acting peripherally, infiltrating the brain, or releasing mediators that can protect or harm neurons. However, the sequence of the changes and the significance of each immune compartment in the disease remain to be clarified. In this review, we describe current understanding of the peripheral immune response in PD and discuss the road ahead.
    MeSH term(s) Humans ; Parkinson Disease ; Central Nervous System ; Neurons ; Brain ; Immunity
    Language English
    Publishing date 2023-08-17
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 282488-7
    ISSN 1878-108X ; 0378-5912 ; 0166-2236
    ISSN (online) 1878-108X
    ISSN 0378-5912 ; 0166-2236
    DOI 10.1016/j.tins.2023.07.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Change in injury pattern with mandatory, referred access compared to open access in an emergency department.

    Melchiorsen, Emma / Rck, Niels Dieter / Lauritsen, Jens

    Danish medical journal

    2024  Volume 71, Issue 3

    Abstract: Introduction: This retrospective cohort study aimed to examine whether implementing mandatory referral changed the composition of patients visiting the Accident and Emergency (A and E) Department in relation to severity, demographics and activity at ... ...

    Abstract Introduction: This retrospective cohort study aimed to examine whether implementing mandatory referral changed the composition of patients visiting the Accident and Emergency (A and E) Department in relation to severity, demographics and activity at injury.
    Methods: Patients visiting the A and E Department at Odense University Hospital, Denmark, in 2008-2019, were divided into three time periods: before (four years before any changes in the operation of the A and E), transition period (the four years during which mandatory referral and the centralised emergency medical service were implemented) and after (the four years after these changes had been implemented). The incidence rate ratios and odds were calculated.
    Results: The absolute number of severe injuries declined, but to a lesser extent than the number of minor injuries. The incidence rate ratios throughout all subcategories, including severity, fracture, sex, age and activity at injury, indicate a smaller risk of visiting the A and E Department in the after period than in the before period, with a total lower (0.82 times; 95% confidence interval: 0.82-0.83 times) risk of visiting the A and E Department in the after period than in the before period.
    Conclusions: Changing from open to referred access altered the composition of injuries for patients seen in the A and E Department, indicating a smaller risk of a visit with referred access than with open access. The odds of a visit being due to a major injury increased after implementing referred access, and the number of visits decreased.
    Funding: The Nordentoft Fund TRIAL REGISTRATION. Not relevant.
    MeSH term(s) Humans ; Access to Information ; Emergency Medical Services ; Emergency Service, Hospital ; Fractures, Bone ; Retrospective Studies ; Male ; Female
    Language English
    Publishing date 2024-02-15
    Publishing country Denmark
    Document type Journal Article
    ZDB-ID 2648771-8
    ISSN 2245-1919 ; 2245-1919
    ISSN (online) 2245-1919
    ISSN 2245-1919
    DOI 10.61409/A10220636
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Dynamic Mode Decomposition of Multiphoton and Stimulated Emission Depletion Microscopy Data for Analysis of Fluorescent Probes in Cellular Membranes.

    Wüstner, Daniel / Egebjerg, Jacob Marcus / Lauritsen, Line

    Sensors (Basel, Switzerland)

    2024  Volume 24, Issue 7

    Abstract: An analysis of the membrane organization and intracellular trafficking of lipids often relies on multiphoton (MP) and super-resolution microscopy of fluorescent lipid probes. A disadvantage of particularly intrinsically fluorescent lipid probes, such as ... ...

    Abstract An analysis of the membrane organization and intracellular trafficking of lipids often relies on multiphoton (MP) and super-resolution microscopy of fluorescent lipid probes. A disadvantage of particularly intrinsically fluorescent lipid probes, such as the cholesterol and ergosterol analogue, dehydroergosterol (DHE), is their low MP absorption cross-section, resulting in a low signal-to-noise ratio (SNR) in live-cell imaging. Stimulated emission depletion (STED) microscopy of membrane probes like Nile Red enables one to resolve membrane features beyond the diffraction limit but exposes the sample to a lot of excitation light and suffers from a low SNR and photobleaching. Here, dynamic mode decomposition (DMD) and its variant, higher-order DMD (HoDMD), are applied to efficiently reconstruct and denoise the MP and STED microscopy data of lipid probes, allowing for an improved visualization of the membranes in cells. HoDMD also allows us to decompose and reconstruct two-photon polarimetry images of TopFluor-cholesterol in model and cellular membranes. Finally, DMD is shown to not only reconstruct and denoise 3D-STED image stacks of Nile Red-labeled cells but also to predict unseen image frames, thereby allowing for interpolation images along the optical axis. This important feature of DMD can be used to reduce the number of image acquisitions, thereby minimizing the light exposure of biological samples without compromising image quality. Thus, DMD as a computational tool enables gentler live-cell imaging of fluorescent probes in cellular membranes by MP and STED microscopy.
    MeSH term(s) Fluorescent Dyes ; Microscopy ; Cell Membrane ; Cholesterol ; Lipids
    Chemical Substances Fluorescent Dyes ; Cholesterol (97C5T2UQ7J) ; Lipids
    Language English
    Publishing date 2024-03-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s24072096
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Age-related trends in unintentional injuries among children and adolescents in an urban Danish population 1980-2021. A cohort study of 292,737 children and adolescents.

    Haller, Frederik / Lauritsen, Jens Martin / Faergemann, Christian

    Injury

    2024  Volume 55, Issue 3, Page(s) 111400

    Abstract: Objective: This study describes the age-related trends in unintentional injuries in children and adolescents in an urban population 1980-2021. A retrospective study of all children and adolescents aged 0-17 years treated for unintentional injuries at ... ...

    Abstract Objective: This study describes the age-related trends in unintentional injuries in children and adolescents in an urban population 1980-2021. A retrospective study of all children and adolescents aged 0-17 years treated for unintentional injuries at Odense University Hospital, Denmark 1980-2021.
    Methods: Information about age, gender, place of injury, and diagnoses from the emergency department register. We estimated gender specific annual incidence rates (IRs) in different age groups (0-4, 5-9, 10-14, and 15-17 years) per 1000 population/years. The severity was classified by mild or severe injuries.
    Results: Overall, 292,737 unintentionally injured children and adolescents were included. The median age was 10 years and 57.4 % were boys. The overall IR was 241 (CI: 240-242) for boys and 188 (CI: 187-188) for girls per 1000 population/years. In the study period, the overall incidence decreased by 44 % in boys and by 38 % in girls. The overall IR for severe injuries did not change in the study period, whereas the IR of mild injuries decreased significantly in all age groups in both gender. The upper limbs were the most frequently injured in all age groups for both gender, except for children aged 0-4 years, where lesions mostly occurred in the head or neck. In the youngest age groups 0-4 years and 5-9 years wounds were the most common type of lesion, while bruises were the most common type of lesion in the oldest age groups. Fractures accounted for 14.5 % of the lesions with the highest proportions in the 5-9 years and 10-14 years age group.
    Conclusion: The study provides information, which is useful when coordinating the resources at emergency departments and for planning preventive campaigns targeting different age groups.
    MeSH term(s) Child ; Male ; Female ; Humans ; Adolescent ; Urban Population ; Cohort Studies ; Retrospective Studies ; Incidence ; Denmark/epidemiology ; Wounds and Injuries/epidemiology
    Language English
    Publishing date 2024-02-01
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 218778-4
    ISSN 1879-0267 ; 0020-1383
    ISSN (online) 1879-0267
    ISSN 0020-1383
    DOI 10.1016/j.injury.2024.111400
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: The BCS Energy Gap at High Density.

    Henheik, Joscha / Lauritsen, Asbjørn Bækgaard

    Journal of statistical physics

    2022  Volume 189, Issue 1, Page(s) 5

    Abstract: We study the BCS energy ... ...

    Abstract We study the BCS energy gap
    Language English
    Publishing date 2022-07-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2017302-7
    ISSN 1572-9613 ; 0022-4715
    ISSN (online) 1572-9613
    ISSN 0022-4715
    DOI 10.1007/s10955-022-02965-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Premenstrual dysphoric disorder: A controversial new diagnosis.

    Schroll, Jeppe Bennekou / Lauritsen, Mette Petri

    Acta obstetricia et gynecologica Scandinavica

    2022  Volume 101, Issue 5, Page(s) 482–483

    MeSH term(s) Female ; Humans ; Premenstrual Dysphoric Disorder/diagnosis ; Premenstrual Syndrome/diagnosis
    Language English
    Publishing date 2022-04-20
    Publishing country United States
    Document type Editorial
    ZDB-ID 80019-3
    ISSN 1600-0412 ; 0001-6349
    ISSN (online) 1600-0412
    ISSN 0001-6349
    DOI 10.1111/aogs.14360
    Database MEDical Literature Analysis and Retrieval System OnLINE

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