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  1. Article ; Online: Prospective evaluation of bowel function and quality of life after colon cancer surgery - is it time for routine screening for late sequelae?

    Bräuner, Annette Boesen / Avellaneda, Nicolas / Christensen, Peter / Drewes, Asbjørn Mohr / Emmertsen, Katrine Jøssing / Krogh, Klaus / Laurberg, Søren / Lauritzen, Michael Bødker / Løve, Uffe Schou / Thorlacius-Ussing, Ole / Juul, Therese

    Acta oncologica (Stockholm, Sweden)

    2023  Volume 62, Issue 9, Page(s) 1132–1142

    Abstract: Aim: Bowel dysfunction after colon cancer (CC) surgery is widely neglected in current follow up programmes. This study explored changes in bowel function and quality of life (QoL) from three (3 m) to twelve months (12 m) after surgery in CC patients ... ...

    Abstract Aim: Bowel dysfunction after colon cancer (CC) surgery is widely neglected in current follow up programmes. This study explored changes in bowel function and quality of life (QoL) from three (3 m) to twelve months (12 m) after surgery in CC patients undergoing right- or left-sided colon resection (RightSCR/LeftSCR) and investigated differences between the two groups 12 m after surgery.
    Method: CC patients undergoing surgical resection in 2018-2020 at five surgical departments were included in this population-based prospective cohort study. Included patients completed electronic surveys consisting of a collection of validated scores 3 m and 12 m after surgery.
    Results: A total of 708 CC patients (423 RightSCR, 285 LeftSCR) were included. In RightSCR, no improvement was observed from 3 m to 12 m in most scores/items, on the contrary, symptom
    Conclusion: From 3 m to 12 m no significant change was observed in the majority of bowel function and QoL scores/items, however, some symptoms
    MeSH term(s) Humans ; Defecation ; Fecal Incontinence/etiology ; Quality of Life ; Prospective Studies ; Flatulence ; Early Detection of Cancer ; Gastrointestinal Diseases ; Colonic Neoplasms/surgery ; Surveys and Questionnaires
    Language English
    Publishing date 2023-08-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 896449-x
    ISSN 1651-226X ; 0349-652X ; 0284-186X ; 1100-1704
    ISSN (online) 1651-226X
    ISSN 0349-652X ; 0284-186X ; 1100-1704
    DOI 10.1080/0284186X.2023.2246102
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6348: Show issues Location:
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  2. Article ; Online: Diet and bowel symptoms among colon cancer survivors.

    Borre, Mette / Fassov, Janne / Juul, Therese / Laurberg, Søren / Christensen, Peter / Bräuner, Annette Boesen / Thorlacius Ussing, Ole / Lauritzen, Michael Bødker / Drewes, Asbjørn Mohr / Faaborg, Pia Møller / Krogh, Klaus

    Acta oncologica (Stockholm, Sweden)

    2022  Volume 61, Issue 10, Page(s) 1192–1199

    Abstract: Background: Survival from colon cancer (CC) has improved considerably over the last decades, yet many survivors suffer from late sequelae from treatment. Typical symptoms of bowel dysfunction after treatment of CC are diarrhea, urge for defecation, ... ...

    Abstract Background: Survival from colon cancer (CC) has improved considerably over the last decades, yet many survivors suffer from late sequelae from treatment. Typical symptoms of bowel dysfunction after treatment of CC are diarrhea, urge for defecation, fecal incontinence, bloating and constipation. Most CC survivors make dietary changes to alleviate bowel symptoms. We aimed to describe the self-perceived effects of diet on bowel function among CC survivors and the level of dietary information given.
    Materials and methods: In this cross-sectional study, CC patients from four surgical departments in Denmark completed surveys regarding the effects of diet on their bowel function and whether they had previously received dietary advice. Data concerning sociodemographic characteristics and the surgical procedure (right-sided or left-sided hemicolectomy) were collected from the Danish Colorectal Cancer Group database. Forty-four healthcare professionals specialized in CC completed a questionnaire on how they advise CC. Descriptive statistics were applied.
    Results: Among 1544 patients invited, 1239 (80.4%) responded, and 844 met the inclusion criteria (53% males, median age 72.6 years, median time since surgery 742 days). Among these, 267 (32%) reported that food affected bowel function. Fat was perceived to have a negative effect in 193 (25%), spices in 149 (19%), sweets in 101 (13%) and meat in 99 (13%). There was no association between tumor site and food categories affecting bowel function (
    Conclusion: One-third of CC survivors perceive that food items, especially fat and spices have a negative impact on their bowel function. We found a major discrepancy between healthcare professionals reporting that they provide advice and the proportion of patients remembering this. There is an unmet need for further recognition of the role of diet in CC rehabilitation and for intervention studies of treatment principles.
    MeSH term(s) Male ; Humans ; Aged ; Female ; Cancer Survivors ; Cross-Sectional Studies ; Colonic Neoplasms ; Diet/adverse effects ; Survivors
    Language English
    Publishing date 2022-07-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 896449-x
    ISSN 1651-226X ; 0349-652X ; 0284-186X ; 1100-1704
    ISSN (online) 1651-226X
    ISSN 0349-652X ; 0284-186X ; 1100-1704
    DOI 10.1080/0284186X.2022.2101901
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Småcellet karcinom i analkanalen.

    Lauritzen, Michael Bødker / Lindebjerg, Jan

    Ugeskrift for laeger

    2011  Volume 173, Issue 38, Page(s) 2347–2348

    Abstract: A 77 year-old male presented a locally advanced small cell anal cancer and simultaneous hepatic and glandular deposits. Due to metastatic disease, chemotherapy with carboplatin and etoposide was the primary choice of treatment. Small cell cancer of the ... ...

    Title translation Small cell carcinoma of the anal canal.
    Abstract A 77 year-old male presented a locally advanced small cell anal cancer and simultaneous hepatic and glandular deposits. Due to metastatic disease, chemotherapy with carboplatin and etoposide was the primary choice of treatment. Small cell cancer of the gastrointestinal tract exerts an aggressive clinical course with early metastases and a very poor prognosis. The diagnosis is based on careful histopathological examination and immunohistochemistry. Due to the aggressiveness of this tumor it is of great importance that the pathologist, the oncologist, and the surgeons are aware of this rare type of cancer.
    MeSH term(s) Aged ; Anus Neoplasms/pathology ; Anus Neoplasms/secondary ; Anus Neoplasms/therapy ; Carcinoma, Small Cell/pathology ; Carcinoma, Small Cell/secondary ; Carcinoma, Small Cell/therapy ; Combined Modality Therapy ; Humans ; Male ; Prognosis
    Language Danish
    Publishing date 2011-09-19
    Publishing country Denmark
    Document type Case Reports ; English Abstract ; Journal Article
    ZDB-ID 124102-3
    ISSN 1603-6824 ; 0041-5782
    ISSN (online) 1603-6824
    ISSN 0041-5782
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Systematic screening for late sequelae after colorectal cancer-a feasibility study.

    Juul, Therese / Bräuner, Annette Boesen / Drewes, Asbjørn Mohr / Emmertsen, Katrine Jøssing / Krogh, Klaus / Laurberg, Søren / Lauritzen, Michael Bødker / Thorlacius-Ussing, Ole / Christensen, Peter

    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

    2021  Volume 23, Issue 2, Page(s) 345–355

    Abstract: Aim: The aim of this study was to test the feasibility of a new method for systematic screening for late sequelae (LS) following colorectal cancer treatment.: Method: Patients with colorectal cancer from five Danish hospitals were invited to complete ...

    Abstract Aim: The aim of this study was to test the feasibility of a new method for systematic screening for late sequelae (LS) following colorectal cancer treatment.
    Method: Patients with colorectal cancer from five Danish hospitals were invited to complete a survey about LS at 3, 12, 24 and 36 months after surgery as part of their follow-up. The survey consisted primarily of validated tools, supplemented by a few ad hoc items, measuring bowel, urinary and sexual dysfunction, pain and quality of life and an additional question regarding request for contact. Patients completed surveys electronically or on paper.
    Results: Of the 1721 invited patients, 1386 (80.5%) were included (1085 with colon cancer and 301 with rectal cancer) of whom 72.5% responded electronically. Patients responding electronically were 7.6 years younger than those responding on paper (P < 0.001). Since some patients answered more than once, the dataset consisted of 2361 surveys. Patients with colon cancer requested phone contact in 19.0% of the surveys, and 8.4% were referred to treatment for LS, primarily bowel dysfunction. Among patients with rectal cancer, 30.8% requested phone contact and 16.2% were referred for treatment of LS, mainly due to bowel and sexual dysfunction.
    Conclusion: This is the first paper investigating a new method of systematic screening for LS following colorectal cancer using electronic patient-reported outcome measures. The study shows that in the Danish population a high response rate can be obtained with this method and that close to three-quarters of patients respond electronically. Patients with rectal cancer had a higher need for phone contact and treatment of LS than patients with colon cancer.
    MeSH term(s) Early Detection of Cancer ; Feasibility Studies ; Humans ; Quality of Life ; Rectal Neoplasms ; Surveys and Questionnaires
    Language English
    Publishing date 2021-02-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 1440017-0
    ISSN 1463-1318 ; 1462-8910
    ISSN (online) 1463-1318
    ISSN 1462-8910
    DOI 10.1111/codi.15519
    Database MEDical Literature Analysis and Retrieval System OnLINE

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