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Article ; Online: Editorial: Addressing the sustainable development goals "leave no one behind" promise: migration and health.

Chen, Shanquan / Law, Chi Kin / Ming, Wai-Kit / Orlando, Stefano

2023 Volume 11, Page(s) 1192454

MeSH term(s)	Sustainable Development ; Employment ; Socioeconomic Factors
Language	English
Publishing date	2023-05-02
Publishing country	Switzerland
Document type	Editorial ; Research Support, Non-U.S. Gov't
ZDB-ID	2711781-9
ISSN	2296-2565 ; 2296-2565
ISSN (online)	2296-2565
ISSN	2296-2565
DOI	10.3389/fpubh.2023.1192454
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Article ; Online: How do cohabitation and marital status affect mortality risk? Results from a cohort study in Thailand.

Zhao, Jiaying / Law, Chi Kin / Kelly, Matthew / Yiengprugsawan, Vasoontara / Seubsman, Sam-Ang / Sleigh, Adrian

BMJ open

2022 Volume 12, Issue 9, Page(s) e062811

Abstract: Objective: To examine the relationship between baseline union status (ie, including marriage and cohabitation) and mortality, paying attention to gender differentials, through an 11-year follow-up of a large cohort in Thailand.: Design: Cohort data ... ...

Abstract	Objective: To examine the relationship between baseline union status (ie, including marriage and cohabitation) and mortality, paying attention to gender differentials, through an 11-year follow-up of a large cohort in Thailand. Design: Cohort data from Thai Cohort Study (TCS) were linked official death records over an 11-year follow-up period. Setting: Community-based adults in Thailand. Participants: 87 151 Thai adults participated in TCS cohort. Method: Cox regression models measured longitudinal associations between union status and 11-year mortality. Results: From 2005 (baseline) to 2016, persons who cohabited and lived with a partner, married persons but not living with a partner and separated/divorced/widowed people were more likely to die compared with those married and living together with a partner. Those who did not have good family support had a higher death risk than those having good family support.Single or cohabiting women had higher risks of mortality than women who were married and living together with a partner throughout follow-up, while separated/divorced/widowed men had higher risks of mortality than counterpart males. Conclusions: Our study reveals the protective effect of marriage and living together on mortality in Thailand, an understudied setting where institutionalisation of cohabitation is low leading to a limited mortality protection. Public policies for moderating mortality should thus be gender nuanced, culturally and institutionally specific. Also, we demonstrate that in settings such as Thailand, where marital status is not always defined in the same way as in western cultures, the need to measure cohabitation in locally relevant terms is important.
MeSH term(s)	Adult ; Cohort Studies ; Family Characteristics ; Female ; Humans ; Male ; Marital Status ; Marriage ; Thailand/epidemiology
Language	English
Publishing date	2022-09-19
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2599832-8
ISSN	2044-6055 ; 2044-6055
ISSN (online)	2044-6055
ISSN	2044-6055
DOI	10.1136/bmjopen-2022-062811
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Article ; Online: A Projection of Future Hospitalisation Needs in a Rapidly Ageing Society: A Hong Kong Experience.

Wu, Xueyuan / Law, Chi-Kin / Yip, Paul Siu Fai

International journal of environmental research and public health

2019 Volume 16, Issue 3

Abstract: To assess the impact of ageing on hospitalisation in a rapidly ageing society. A study using retrospective and prospective data was conducted using hospitalisation data with age-specific admission rates in the period from 2001⁻2010 and demographic data ... ...

Abstract	To assess the impact of ageing on hospitalisation in a rapidly ageing society. A study using retrospective and prospective data was conducted using hospitalisation data with age-specific admission rates in the period from 2001⁻2010 and demographic data from the period of 2001⁻2066 by the United Nations. The Hong Kong Special Administrative Region (SAR) with a 7 million population experiences extreme low fertility (1.1 children per woman) and long life expectancy (84 years old). Days of hospitalisation: For the period 2010⁻2066, the length of stay (LOS) in the age group 85+ is projected to increase by 555.3% while the LOS for the whole population is expected to increase by only 134.4% and by ageing only. In 2010, the proportion in the LOS contributed to by the oldest age group (85+) was 15%. In 2066, this proportion is projected to nearly triple (42%). Around 70% of the projected days of hospitalisation would be taken by people aged 75 years and above. It is projected that this phenomenon would be converted to a more balanced structure when the demographic transition changes into a more stable distribution. Apparently, the impact of ageing on the public hospital system has not been well understood and prepared. The determined result provides insight into monitoring the capacity of the hospital system to cope with a rapidly changing demographic society. It provides empirical evidence of the impact of ageing on the public hospitalisation system. It gives a long term projection up to the year 2066 while the situation would be different from the transient period of 2016⁻2030. The analysis adopts a fixed rate approach, which assumes the LOS to be only driven by demographic factors, while any improvements in health technologies and health awareness are not accounted for. Only inpatient data from the Hospital Authority were used, nonetheless, they are the best available for the study. Due to the limitation of data, proximity to death is not controlled in conducting this analysis.
MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; Aging ; Child ; Demography ; Female ; Forecasting ; Health Services for the Aged/statistics & numerical data ; Health Services for the Aged/trends ; Hong Kong/epidemiology ; Hospitalization/statistics & numerical data ; Hospitalization/trends ; Humans ; Life Expectancy/trends ; Male ; Middle Aged ; Population Dynamics/statistics & numerical data ; Population Dynamics/trends ; Prospective Studies ; Retrospective Studies
Language	English
Publishing date	2019-02-06
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1660-4601
ISSN (online)	1660-4601
DOI	10.3390/ijerph16030473
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Article: The Cost Consequences of the Gold Coast Integrated Care Programme.

Ward, Lauren / McMurray, Anne / Law, Chi Kin / Mihala, Gabor / Connor, Martin / Scuffham, Paul

International journal of integrated care

2021 Volume 21, Issue 3, Page(s) 9

Abstract: Introduction: The Australian Gold Coast Integrated Care programme trialled a model of care targeting those with chronic and complex conditions at highest risk of hospitalisation with the goal of producing the best patient outcomes at no additional cost ... ...

Abstract	Introduction: The Australian Gold Coast Integrated Care programme trialled a model of care targeting those with chronic and complex conditions at highest risk of hospitalisation with the goal of producing the best patient outcomes at no additional cost to the healthcare system. This paper reports the economic findings of the trial. Methods: A pragmatic non-randomised controlled study assessed differences between patients enrolled in the programme (intervention group) and patients who received usual care (control group), in health service utilisation, including Medicare Benefits Schedule and Pharmaceutical Benefits Scheme claims, patient-reported outcome measures, including health-related quality of life, mortality risk, and cost. Results: A total of 1,549 intervention participants were enrolled and matched on the basis of patient level data to 3,042 controls. We found no difference in quality of life between groups, but a greater decrease in capability, social support and satisfaction with care scores and higher hospital service use for the intervention group, leading to a greater cost to the healthcare system of AUD$6,400 per person per year. In addition, the per person per year cost of being in the GCIC programme was AUD$8,700 equating to total healthcare expenditures of AUD$15,100 more for the intervention group than the control group. Conclusion: The GCIC programme did not show value for money, incurring additional costs to the health system and demonstrating no significant improvements in health-related quality of life. Because patient recruitment was gradual throughout the trial, we had only one year of complete data for analysis which may be too short a period to determine the true cost-consequences of the program.
Language	English
Publishing date	2021-09-15
Publishing country	England
Document type	Journal Article
ZDB-ID	2119289-3
ISSN	1568-4156
ISSN	1568-4156
DOI	10.5334/ijic.5542
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Article ; Online: Revisiting knowledge, attitudes and practice (KAP) on human papillomavirus (HPV) vaccination among female university students in Hong Kong.

Leung, Jonathan Tin Chi / Law, Chi-Kin

Human vaccines & immunotherapeutics

2018 Volume 14, Issue 4, Page(s) 924–930

Abstract: Despite cervical cancer can be preventable by HPV vaccination, little is known on its associated factors among young females in Hong Kong. This study aimed to investigate the present situation regarding the self-reported knowledge, attitudes and practice ...

Abstract	Despite cervical cancer can be preventable by HPV vaccination, little is known on its associated factors among young females in Hong Kong. This study aimed to investigate the present situation regarding the self-reported knowledge, attitudes and practice (KAP) of Human Papillomavirus (HPV) vaccination and to examine their associated factors among female university students in Hong Kong. 195 respondents were recruited to complete a self-administered questionnaire from two local universities through convenience sampling. 8.2% respondents indicated that family doctors as sources of knowledge of HPV and HPV vaccination. 59.0% of the sample identified more than four knowledge items, 82.6% thought that HPV vaccines can effectively prevent cervical cancer and 47.2% received HPV vaccination. Regression analyses found those at older age, thought that they might be infected by HPV and received HPV would have a higher level of knowledge. Those who knew HPV is sexually transmitted, thought may be infected by HPV and received HPV vaccination would have positive attitude on HPV vaccination. Those at older ages, knew their university provided discounted vaccination for female students, and were not afraid of the side effects were associated with HPV vaccination. Family doctors should take a more prominent role in disseminating accurate and precise information. Advocacies should be emphasised on the risk of HPV as a sexually transmitted disease and the availability of discounted and safe HPV vaccines in tertiary educational institutions to increase the uptake rate of HPV vaccines for first-year and non-health major university students.
MeSH term(s)	Female ; Health Knowledge, Attitudes, Practice ; Hong Kong ; Humans ; Papillomaviridae/immunology ; Papillomavirus Infections/immunology ; Papillomavirus Infections/prevention & control ; Papillomavirus Infections/psychology ; Papillomavirus Vaccines/immunology ; Patient Acceptance of Health Care ; Schools ; Sexual Behavior/psychology ; Students/psychology ; Universities ; Uterine Cervical Neoplasms/immunology ; Uterine Cervical Neoplasms/prevention & control ; Uterine Cervical Neoplasms/psychology ; Uterine Cervical Neoplasms/virology ; Vaccination/psychology
Chemical Substances	Papillomavirus Vaccines
Language	English
Publishing date	2018-01-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	2664176-8
ISSN	2164-554X ; 2164-5515
ISSN (online)	2164-554X
ISSN	2164-5515
DOI	10.1080/21645515.2017.1415685
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Article ; Online: ASO Author Reflections: Is laparoscopic-Assisted Surgery More Costly than Traditional Open Resection for Rectal Cancer Treatment?

Law, Chi Kin / Stevenson, Andrew R L / Solomon, Michael / Hague, Wendy / Wilson, Kate / Simes, John R / Morton, Rachael L

Annals of surgical oncology

2022 Volume 29, Issue 3, Page(s) 1935–1936

Language	English
Publishing date	2022-01-13
Publishing country	United States
Document type	Journal Article
ZDB-ID	1200469-8
ISSN	1534-4681 ; 1068-9265
ISSN (online)	1534-4681
ISSN	1068-9265
DOI	10.1245/s10434-021-11056-0
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Article ; Online: Association of dietary risks, behavioural and lifestyle factors, and the magnitude of disability burden among Australian cancer patients: An observational epidemiology study.

Mahumud, Rashidul Alam / Sultana, Marufa / Gow, Jeff / Rahman, Md Ashfikur / Uddin, Khandakar Farid / Kamal, Mostafa / Alam, Khorshed / Dawson, Angela / Law, Chi Kin

Cancer epidemiology

2022 Volume 78, Page(s) 102161

Abstract: Background: Cancer patients are confronted with a variety of other health-related issues, including physical disability, poor quality of life, and psychological challenges. This study aims to quantify the association of dietary, behavioural and ... ...

Abstract	Background: Cancer patients are confronted with a variety of other health-related issues, including physical disability, poor quality of life, and psychological challenges. This study aims to quantify the association of dietary, behavioural and lifestyle risk factors and comorbidities on the magnitude and distribution of disability burden among cancer patients in Australia. Methods: This study comprised a sample of 2283 cancer patients drawn from the latest nationwide Australian National Health Survey conducted in 2017-18. Negative binomial regression models were used to estimate the incidence rate ratio (IRR) of the number of disabilities and its associations. Results: Forty-five percent of cancer patients experienced at least one disability. The magnitude of disability was significantly associated with sugar-sweetened drink consumption ≥ 3 days per week (IRR= 1.12, 95% CI: 1.02-1.26), a lack of physical activity (IRR = 1.69, 1.38-2.07), frequent or regular alcohol consumption (IRR = 1.95, 1.84-2.08), poor health status (IRR = 1.99, 1.78-2.24) and the presence of five or more chronic comorbid conditions (IRR = 3.59, 2.90-4.46). Cancer patients who consumed vegetables at least two or more times per day had a 10% lower risk of disability burden (IRR = 0.90, 0.82-0.99). Conclusions: This study shows the association of diet, behavioural, and lifestyle risk factors on the degree of disability burden among cancer patients, highlighting the need for bold and effective policies. The findings will inform the implementation of evidence-based lifestyle interventions and offer a foundation for evaluating their influence on cancer survivors' health.
MeSH term(s)	Australia/epidemiology ; Diet/adverse effects ; Disabled Persons ; Humans ; Life Style ; Neoplasms/epidemiology ; Quality of Life
Language	English
Publishing date	2022-04-18
Publishing country	Netherlands
Document type	Journal Article ; Observational Study
ZDB-ID	2508729-0
ISSN	1877-783X ; 1877-7821
ISSN (online)	1877-783X
ISSN	1877-7821
DOI	10.1016/j.canep.2022.102161
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Article ; Online: The incomparability of cause of death statistics under "one country, two systems": Shanghai versus Hong Kong.

Zhao, Jiaying / Tu, Edward Jow-Ching / Law, Chi-Kin

Population health metrics

2017 Volume 15, Issue 1, Page(s) 37

Abstract: Background: Valid and comparable cause of death (COD) statistics are crucial for health policy analyses. Variations in COD assignment across geographical areas are well-documented while socio-institutional factors may affect the process of COD and ... ...

Abstract	Background: Valid and comparable cause of death (COD) statistics are crucial for health policy analyses. Variations in COD assignment across geographical areas are well-documented while socio-institutional factors may affect the process of COD and underlying cause of death (UCD) determination. This study examines the comparability of UCD statistics in Hong Kong and Shanghai, having two political systems within one country, and assesses how socio-institutional factors influence UCD comparability. Methods: A mixed method was used. Quantitative analyses involved anonymized official mortality records. Mortality rates were analyzed by location of death. To analyze the odds ratio of being assigned to a particular UCD, logistic regressions were performed. Qualitative analyses involved literature reviews and semi-structural interviews with key stakeholders in death registration practices. Thematic analysis was used. Results: Age-standardized death rates from certain immediate conditions (e.g., septicemia, pneumonia, and renal failure) were higher in Hong Kong. Variations in UCD determination may be attributed to preference of location of death, procedures of registering deaths outside hospital, perceptions on the causal chain of COD, implications of the selected UCD for doctors' professional performance, and governance and processes of data quality review. Conclusions: Variations in socio-institutional factors were related to the process of certifying and registering COD in Hong Kong and Shanghai. To improve regional data comparability, health authorities should develop standard procedures for registering deaths outside hospital, provide guidelines and regular training for doctors, develop a unified automated coding system, consolidate a standard procedure for data review and validity checks, and disseminate information concerning both UCD and multiple causes of death.
MeSH term(s)	Cause of Death ; China ; Death ; Female ; Government ; Hong Kong ; Humans ; Logistic Models ; Male ; Odds Ratio ; Physicians ; Politics ; Professional Competence ; Quality Control ; Registries/standards
Language	English
Publishing date	2017-09-29
Publishing country	England
Document type	Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2127230-X
ISSN	1478-7954 ; 1478-7954
ISSN (online)	1478-7954
ISSN	1478-7954
DOI	10.1186/s12963-017-0155-z
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Article ; Online: Long-term cost-effectiveness of a melanoma prevention program using genomic risk information compared with standard prevention advice in Australia.

Law, Chi Kin / Cust, Anne E / Smit, Amelia K / Trevena, Lyndal / Fernandez-Penas, Pablo / Nieweg, Omgo E / Menzies, Alexander M / Wordsworth, Sarah / Morton, Rachael L

Genetics in medicine : official journal of the American College of Medical Genetics

2023 Volume 25, Issue 12, Page(s) 100970

Abstract: Purpose: Evidence indicates that a melanoma prevention program using personalized genomic risk provision and genetic counseling can affect prevention behaviors, including reducing sunburns in adults with no melanoma history. This analysis evaluated its ... ...

Abstract	Purpose: Evidence indicates that a melanoma prevention program using personalized genomic risk provision and genetic counseling can affect prevention behaviors, including reducing sunburns in adults with no melanoma history. This analysis evaluated its longer-term cost-effectiveness from an Australian health system perspective. Methods: The primary outcome was incremental cost effectiveness ratio (ICER) of genomic risk provision (intervention) compared with standard prevention advice. A decision-analytic Markov model was developed using randomized trial data to simulate lifetime cost-effectiveness. All costs were presented in 2018/19 Australian dollars (AUD). The intervention effect on reduced sunburns was stratified by sex and traditional risk, which was calculated through a validated prediction model. Deterministic and probabilistic sensitivity analyses were undertaken for robustness checks. Results: The per participant cost of intervention was AUD$189. Genomic risk provision targeting high-traditional risk individuals produced an ICER of AUD$35,254 (per quality-adjusted life year gained); sensitivity analyses indicated the intervention would be cost-effective in more than 50% of scenarios. When the intervention was extended to low-traditional risk groups, the ICER was AUD$43,746 with a 45% probability of being cost-effective. Conclusion: Genomic risk provision targeted to high-traditional melanoma risk individuals is likely a cost-effective strategy for reducing sunburns and will likely prevent future melanomas and keratinocyte carcinomas.
MeSH term(s)	Adult ; Humans ; Melanoma/genetics ; Melanoma/prevention & control ; Australia ; Cost-Benefit Analysis ; Cost-Effectiveness Analysis ; Sunburn ; Genomics ; Risk Factors ; Quality-Adjusted Life Years
Language	English
Publishing date	2023-08-30
Publishing country	United States
Document type	Journal Article
ZDB-ID	1455352-1
ISSN	1530-0366 ; 1098-3600
ISSN (online)	1530-0366
ISSN	1098-3600
DOI	10.1016/j.gim.2023.100970
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Article ; Online: Coordinated Management of COVID-19 Response: Lessons From Whole-of-Society and Whole-of-Health Strategies in Wuhan, China.

Chen, Shanquan / Zhang, Pan / Zhang, Yun / Fung, Hong / Han, Yong / Law, Chi Kin / Li, Zhiqiang

Frontiers in public health

2021 Volume 9, Page(s) 664214

Abstract: Background: ...

Abstract	Background:
MeSH term(s)	COVID-19 ; China/epidemiology ; Humans ; Pandemics ; Retrospective Studies ; SARS-CoV-2
Language	English
Publishing date	2021-08-03
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2711781-9
ISSN	2296-2565 ; 2296-2565
ISSN (online)	2296-2565
ISSN	2296-2565
DOI	10.3389/fpubh.2021.664214
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