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  1. Book: DeVita, Hellman, and Rosenberg's cancer

    DeVita, Vincent T. / Lawrence, Theodore S. / Rosenberg, Steven A.

    principles and practice of oncology

    2023  

    Title variant Cancer
    Author's details editors, Vincent T. DeVita Jr., Theodore S. Lawrence, Steven A. Rosenberg
    Keywords Neoplasms / genetics ; Neoplasms / physiopathology ; Molecular Biology / methods ; Oncology
    Subject code 616.994
    Language English
    Size xxx, 1880, I-48 Seiten, Illustrationen, Diagramme, 28 cm
    Edition 12 edition
    Publisher Wolters Kluwer
    Publishing place Philadelphia
    Publishing country United States
    Document type Book
    Accompanying material Zugang zu eBook über Code
    HBZ-ID HT021729117
    ISBN 978-1-9751-8474-2 ; 1-9751-8474-2
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2023 A 422 available for loan (reading room) Lesesaal EG
    Zugang zu zusätzlichem Internetmaterial über Code aus lizenzrechtlichen Gründen nicht verfügbar

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  2. Book ; Online ; E-Book: Devita, Hellman, and Rosenberg's cancer

    DeVita, Vincent T. / Lawrence, Theodore S. / Rosenberg, Steven A.

    principles & practice of oncology : primer of the molecular biology of cancer

    2021  

    Title variant Cancer ; Primer of the molecular biology of cancer
    Author's details Vincent T. DeVita, Jr., Theodore S. Lawrence, Steven A. Rosenberg editors
    Keywords Electronic books ; Neoplasms / etiology ; Neoplasms / genetics ; Neoplasms / physiopathology ; Molecular Biology / methods
    Language English
    Size 1 Online-Ressource (1011 Seiten), Illustrationen, Diagramme
    Edition Third edition
    Publisher Wolters Kluwer
    Publishing place Philadelphia
    Publishing country United States
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT020914691
    ISBN 978-1-975149-13-0 ; 9781975149116 ; 1-975149-13-0 ; 1975149114
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

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    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article ; Online: Revising a Research Paper.

    Lawrence, Theodore S

    International journal of radiation oncology, biology, physics

    2021  Volume 109, Issue 2, Page(s) 332–334

    MeSH term(s) Publications ; Research ; Writing
    Language English
    Publishing date 2021-01-09
    Publishing country United States
    Document type Editorial
    ZDB-ID 197614-x
    ISSN 1879-355X ; 0360-3016
    ISSN (online) 1879-355X
    ISSN 0360-3016
    DOI 10.1016/j.ijrobp.2020.09.035
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1218: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Writing a Research Paper.

    Lawrence, Theodore S

    International journal of radiation oncology, biology, physics

    2020  Volume 106, Issue 4, Page(s) 674–676

    MeSH term(s) Publications ; Research ; Writing
    Language English
    Publishing date 2020-02-21
    Publishing country United States
    Document type Editorial
    ZDB-ID 197614-x
    ISSN 1879-355X ; 0360-3016
    ISSN (online) 1879-355X
    ISSN 0360-3016
    DOI 10.1016/j.ijrobp.2019.12.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1218: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Book ; Conference proceedings: Emerging targeted therapies in combination with radiation

    Lawrence, Theodore S.

    [proceedings of a satellite symposium at the 43rd annual meeting of the American Society for Therapeutic Radiology and Oncology (ASTRO) held on November 6, 2001 in San Francisco, CA]

    (Seminars in radiation oncology ; 12,3, Suppl. 2)

    2002  

    Institution American Society for Therapeutic Radiology and Oncology
    Author's details Theodore S. Lawrence, guest ed
    Series title Seminars in radiation oncology ; 12,3, Suppl. 2
    Collection
    Keywords Strahlentherapie
    Subject Bestrahlung ; Radiotherapie ; Strahlenbehandlung ; Radioonkologie
    Language English
    Size 45 S. : graph. Darst.
    Publisher Saunders
    Publishing place Philadelphia, Pa
    Publishing country United States
    Document type Book ; Conference proceedings
    HBZ-ID HT013451652
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 3654 -12,Suppl.2- not available for loan Zeitschriften-Lesesaal

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  6. Book: Cancer

    DeVita, Vincent T. / Lawrence, Theodore S. / Rosenberg, Steven A.

    principles & practice of oncology ; primer of the molecular biology of cancer

    (Oncology)

    2015  

    Author's details editors Vincent T. DeVita, Jr., MD, Amy & Joseph Perella Professor of Medicine, Yale Comprehensive Cancer Center and Smilow Cancer Hospital at Yale-New Haven, Professor of Epidemiology and Public Health, Yale University School of Public Health, New Haven, Connecticut, Theodore S. Lawrence, MD, PhD, Isadore Lampe Professor and Chair, Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan, Steven A. Rosenberg, MD, PhD, Chief, Surgery Branch, National Cancer Institute, National Institutes of Health, Professor of Surgery, Uniformed Services University of the Health Sciences, School of Medicine, Bethesda, Maryland, Professor of Surgery, George Washington University School of Medicine, Washington, District of Columbia; with 82 contributin authors
    Series title Oncology
    Keywords Molecular Biology / methods ; Neoplasms / physiopathology ; Neoplasms / genetics ; Neoplasms / etiology
    Language English
    Size xiv, 519 Seiten, Illustrationen, Diagramme, 26 cm
    Edition Second edition
    Publisher Wolters Kluwer
    Publishing place Philadelphia
    Publishing country United States
    Document type Book
    Accompanying material Zugang zu Online-Ausgabe über Code
    HBZ-ID HT019137075
    ISBN 978-1-4963-1063-7 ; 1-4963-1063-2
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2016 A 2580 available for loan (reading room) Lesesaal EG

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  7. Article ; Online: Evolution of Response-Based Radiotherapy for Hepatocellular Cancer.

    Elaimy, Ameer L / Cao, Yue / Lawrence, Theodore S

    Cancer journal (Sudbury, Mass.)

    2023  Volume 29, Issue 5, Page(s) 266–271

    Abstract: Abstract: Stereotactic body radiation therapy has emerged as a safe and effective treatment modality for properly selected hepatocellular cancer (HCC) patients with normal liver function. However, many HCC patients have reduced baseline liver function ... ...

    Abstract Abstract: Stereotactic body radiation therapy has emerged as a safe and effective treatment modality for properly selected hepatocellular cancer (HCC) patients with normal liver function. However, many HCC patients have reduced baseline liver function due to underlying cirrhosis or prior liver-directed therapies. Therefore, because of the increased risk of hepatotoxicity, the use of stereotactic body radiation therapy for patients with reduced liver function has been approached with caution. Individualized, response-based radiotherapy incorporates models, imaging tools, and biomarkers that determine the dose-response relationship of the liver before, during, and after treatment and has been useful in reducing the likelihood of liver damage without sacrificing tumor control. This review discusses the evolution of response-based radiotherapy for HCC and highlights areas for further investigation.
    MeSH term(s) Humans ; Liver Neoplasms/pathology ; Carcinoma, Hepatocellular/radiotherapy ; Treatment Outcome ; Radiotherapy Dosage ; Radiosurgery/adverse effects ; Radiosurgery/methods
    Language English
    Publishing date 2023-10-05
    Publishing country United States
    Document type Review ; Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2018400-1
    ISSN 1540-336X ; 1528-9117 ; 1081-4442
    ISSN (online) 1540-336X
    ISSN 1528-9117 ; 1081-4442
    DOI 10.1097/PPO.0000000000000679
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4470: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 163: Show issues

    Order via subito

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  8. Book ; Online: Devita, Hellman & Rosenberg's Cancer

    DeVita, Vincent T. / Lawrence, Theodore S. / Rosenberg, Steven A.

    principles & practice of oncology

    2011  

    Title variant Cancer
    Author's details [edited by] Vincent T. DeVita Jr., Theodore S. Lawrence, Steven A. Rosenberg
    Keywords Neoplasms
    Language English
    Size 1 Online-Ressource (3456 Seiten)
    Edition 9th ed.
    Publisher Wolters Kluwer Health/Lippincott Williams & Wilkins
    Publishing place Philadelphia
    Document type Book ; Online
    Note Includes bibliographical references and index
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 978-1-451-10545-2 ; 978-1-608-31625-0 ; 1-608-31625-4 ; 1-451-10545-2
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

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    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  9. Article ; Online: Is Apparent Diffusion Coefficient Established as an Imaging Biomarker for Stereotactic Body Radiation Therapy Assessment in Hepatocellular Carcinoma?

    Cao, Yue / Cuneo, Kyle C / Evans, Joseph / Ten Haken, Randall K / Chang, Daniel T / Lawrence, Theodore S

    Cancer journal (Sudbury, Mass.)

    2024  Volume 29, Issue 4, Page(s) 238–242

    Abstract: Abstract: In this article, as part of this special issue on biomarkers of early response, we review currently available reports regarding magnetic resonance imaging apparent diffusion coefficient (ADC) changes in hepatocellular carcinoma (HCC) in ... ...

    Abstract Abstract: In this article, as part of this special issue on biomarkers of early response, we review currently available reports regarding magnetic resonance imaging apparent diffusion coefficient (ADC) changes in hepatocellular carcinoma (HCC) in response to stereotactic body radiation therapy. We compare diffusion image acquisition, ADC analysis, methods for HCC response assessment, and statistical methods for prediction of local tumor progression by ADC metrics. We discuss the pros and cons of these studies. Following detailed analyses of existing investigations, we cannot conclude that ADC is established as an imaging biomarker for stereotactic body radiation therapy assessment in HCC.
    MeSH term(s) Humans ; Carcinoma, Hepatocellular/diagnostic imaging ; Carcinoma, Hepatocellular/radiotherapy ; Liver Neoplasms/diagnostic imaging ; Liver Neoplasms/radiotherapy ; Diffusion Magnetic Resonance Imaging/methods ; Magnetic Resonance Imaging ; Biomarkers ; Retrospective Studies
    Chemical Substances Biomarkers
    Language English
    Publishing date 2024-01-01
    Publishing country United States
    Document type Review ; Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2018400-1
    ISSN 1540-336X ; 1528-9117 ; 1081-4442
    ISSN (online) 1540-336X
    ISSN 1528-9117 ; 1081-4442
    DOI 10.1097/PPO.0000000000000668
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 4470: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 163: Show issues

    Order via subito

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  10. Article ; Online: Isoform alterations in the ubiquitination machinery impacting gastrointestinal malignancies.

    Kasturirangan, Srimathi / Nancarrow, Derek J / Shah, Ayush / Lagisetty, Kiran H / Lawrence, Theodore S / Beer, David G / Ray, Dipankar

    Cell death & disease

    2024  Volume 15, Issue 3, Page(s) 194

    Abstract: The advancement of RNAseq and isoform-specific expression platforms has led to the understanding that isoform changes can alter molecular signaling to promote tumorigenesis. An active area in cancer research is uncovering the roles of ubiquitination on ... ...

    Abstract The advancement of RNAseq and isoform-specific expression platforms has led to the understanding that isoform changes can alter molecular signaling to promote tumorigenesis. An active area in cancer research is uncovering the roles of ubiquitination on spliceosome assembly contributing to transcript diversity and expression of alternative isoforms. However, the effects of isoform changes on functionality of ubiquitination machineries (E1, E2, E3, E4, and deubiquitinating (DUB) enzymes) influencing onco- and tumor suppressor protein stabilities is currently understudied. Characterizing these changes could be instrumental in improving cancer outcomes via the identification of novel biomarkers and targetable signaling pathways. In this review, we focus on highlighting reported examples of direct, protein-coded isoform variation of ubiquitination enzymes influencing cancer development and progression in gastrointestinal (GI) malignancies. We have used a semi-automated system for identifying relevant literature and applied established systems for isoform categorization and functional classification to help structure literature findings. The results are a comprehensive snapshot of known isoform changes that are significant to GI cancers, and a framework for readers to use to address isoform variation in their own research. One of the key findings is the potential influence that isoforms of the ubiquitination machinery have on oncoprotein stability.
    MeSH term(s) Humans ; Ubiquitination ; Protein Isoforms/genetics ; Protein Isoforms/metabolism ; Gastrointestinal Neoplasms/genetics ; Carcinogenesis ; Tumor Suppressor Proteins/metabolism ; Ubiquitin-Protein Ligases/metabolism
    Chemical Substances Protein Isoforms ; Tumor Suppressor Proteins ; Ubiquitin-Protein Ligases (EC 2.3.2.27)
    Language English
    Publishing date 2024-03-08
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2541626-1
    ISSN 2041-4889 ; 2041-4889
    ISSN (online) 2041-4889
    ISSN 2041-4889
    DOI 10.1038/s41419-024-06575-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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