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  1. Article ; Online: Intravenous Thrombolysis for Stroke in a COVID-19 Positive Filipino Patient, a Case Report.

    Co, Christian Oliver C / Yu, Jeryl Ritzi T / Laxamana, Lina C / David-Ona, Deborah Ignacia A

    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

    2020  Volume 77, Page(s) 234–236

    Abstract: The 2019 Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) which was first reported in Wuhan, China last December 2019, has been declared an emergency by the World Health Organization but eventually progressed to become a Pandemic. To date, ... ...

    Abstract The 2019 Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) which was first reported in Wuhan, China last December 2019, has been declared an emergency by the World Health Organization but eventually progressed to become a Pandemic. To date, Coronavirus Disease 2019 (COVID-19) has affected at least 100,000 individuals worldwide, reaching thousands of mortalities (Zhou et al., 2020; World Health Organization, 2020). In the Philippines, the number of COVID-19 confirmed positive cases is over 636 and is expected to rise (Department of Health, 2020). Respiratory infections alongside their comorbidities can induce acute myocardial infarction and acute ischemic stroke (Warren-Gash et al., 2018) [3]. These may further bring challenges in the management and administration of Intravenous (IV) Alteplase in eligible patients. Currently, there are no case reports in the administration IV Altepase in ischemic stroke patients who are COVID-19 positive. We present a case of a 62-year old female who was admitted due to cough, colds and shortness of breath of 2 weeks duration and was tested to be COVD-19 positive. She suffered from an ischemic stroke while in the Medical Intensive Care Unit and was given Intravenous thrombolysis.
    MeSH term(s) Administration, Intravenous ; Betacoronavirus/pathogenicity ; COVID-19 ; Coronavirus Infections/complications ; Coronavirus Infections/drug therapy ; Coronavirus Infections/virology ; Female ; Humans ; Middle Aged ; Pandemics ; Philippines ; Pneumonia, Viral/complications ; Pneumonia, Viral/drug therapy ; Pneumonia, Viral/virology ; SARS-CoV-2 ; Stroke/drug therapy ; Stroke/etiology ; Stroke/virology ; Thrombolytic Therapy/methods ; Tissue Plasminogen Activator/administration & dosage ; Tissue Plasminogen Activator/therapeutic use
    Chemical Substances Tissue Plasminogen Activator (EC 3.4.21.68)
    Keywords covid19
    Language English
    Publishing date 2020-05-11
    Publishing country Scotland
    Document type Case Reports
    ZDB-ID 1193674-5
    ISSN 1532-2653 ; 0967-5868
    ISSN (online) 1532-2653
    ISSN 0967-5868
    DOI 10.1016/j.jocn.2020.05.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3999: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article: Intravenous Thrombolysis for Stroke in a COVID-19 Positive Filipino Patient, a Case Report

    Co, Christian Oliver C / Yu, Jeryl Ritzi T / Laxamana, Lina C / David-Ona, Deborah Ignacia A

    J Clin Neurosci

    Abstract: The 2019 Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) which was first reported in Wuhan, China last December 2019, has been declared an emergency by the World Health Organization but eventually progressed to become a Pandemic. To date, ... ...

    Abstract The 2019 Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) which was first reported in Wuhan, China last December 2019, has been declared an emergency by the World Health Organization but eventually progressed to become a Pandemic. To date, Coronavirus Disease 2019 (COVID-19) has affected at least 100,000 individuals worldwide, reaching thousands of mortalities (Zhou et al., 2020; World Health Organization, 2020). In the Philippines, the number of COVID-19 confirmed positive cases is over 636 and is expected to rise (Department of Health, 2020). Respiratory infections alongside their comorbidities can induce acute myocardial infarction and acute ischemic stroke (Warren-Gash et al., 2018) [3]. These may further bring challenges in the management and administration of Intravenous (IV) Alteplase in eligible patients. Currently, there are no case reports in the administration IV Altepase in ischemic stroke patients who are COVID-19 positive. We present a case of a 62-year old female who was admitted due to cough, colds and shortness of breath of 2 weeks duration and was tested to be COVD-19 positive. She suffered from an ischemic stroke while in the Medical Intensive Care Unit and was given Intravenous thrombolysis.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #32414622
    Database COVID19

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  3. Article ; Online: Intravenous Thrombolysis for Stroke in a COVID-19 Positive Filipino Patient, a Case Report

    Co, Christian Oliver C. / Yu, Jeryl Ritzi T. / Laxamana, Lina C. / David-Ona, Deborah Ignacia A.

    Journal of Clinical Neuroscience

    2020  Volume 77, Page(s) 234–236

    Keywords Physiology (medical) ; Neurology ; Clinical Neurology ; General Medicine ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 1193674-5
    ISSN 0967-5868
    ISSN 0967-5868
    DOI 10.1016/j.jocn.2020.05.006
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    Zs.A 3999: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Dabigatran Reversal With Idarucizumab Preceding Thrombolysis in an Octogenarian Patient with Chronic Kidney Disease and Acute Stroke: A Case Report.

    Laxamana, Lina C / Co, Christian Oliver C / Yu, Jeryl Ritzi T / Mojica, Christianne V / Iboleon-Dy, Maria Adelaida M / Domingo, Alyssa Mae C / Ilano, Karen Czarina S / Macrohon-Valdez, Ma Cristina Z

    Clinical therapeutics

    2020  Volume 42, Issue 9, Page(s) 1840–1845

    Abstract: Background and purpose: Reversing the effect of dabigatran among patients with atrial fibrillation is important to normalize coagulation profile among patients who develop serious hemorrhage from any source. However, such intervention always has the ... ...

    Abstract Background and purpose: Reversing the effect of dabigatran among patients with atrial fibrillation is important to normalize coagulation profile among patients who develop serious hemorrhage from any source. However, such intervention always has the potential to cause a prothrombotic state. Among patients suspected of ischemic stroke, Idarucizumab, may be administered preceding thrombolysis. This is a considerable option when given during the critical phase of revascularization.
    Methods: We report the case of an 84-year old, male, banker, known hypertensive with chronic renal disease. He has non valvular atrial fibrillation receiving Dabigatran at 75 mg twice daily and presented with symptoms of right-sided weakness, right hemisensory loss, facial asymmetry, and slurring of speech equating to National Institute of Health Stroke Scale (NIHSS) of 5. After coming into the hospital for a suspected stroke, 3 hours and 25 minutes after symptoms, complete reversal of Dabigatran with Idarucizumab was administered and intravenous thrombolysis was initiated 271 minutes post ictus. There was immediate improvement of the right upper extremity weakness and dysarthria 30 minutes post infusion. At 13 days post ictus, the patient was discharged with minimal right central facial palsy and right arm drift (NIHSS 2). Brain CT scan post revascularization did not reveal any hemorrhage and anticoagulant Apixaban 2.5 mg twice daily was started and maintained thereafter. Brain Magnetic Resonance Angiogram (MRA) showed complete recanalization of the left proximal MCA after 52 days.
    Conclusion: Our case showed the effectiveness and safety of giving Idarucizumab followed by thrombolysis in Dabigatran-treated atrial fibrillation with ischemic stroke. Based on this case, the procedure can be performed in an elderly population with chronic kidney disease when administered close to the limit of threshold for thrombolysis.
    MeSH term(s) Administration, Intravenous ; Aged, 80 and over ; Antibodies, Monoclonal, Humanized/administration & dosage ; Antithrombins/administration & dosage ; Antithrombins/adverse effects ; Atrial Fibrillation/drug therapy ; Dabigatran/adverse effects ; Dabigatran/therapeutic use ; Humans ; Hypertension/drug therapy ; Male ; Renal Insufficiency, Chronic/drug therapy ; Stroke/drug therapy ; Thrombolytic Therapy/adverse effects ; Thrombolytic Therapy/methods
    Chemical Substances Antibodies, Monoclonal, Humanized ; Antithrombins ; idarucizumab (97RWB5S1U6) ; Dabigatran (I0VM4M70GC)
    Language English
    Publishing date 2020-08-07
    Publishing country United States
    Document type Case Reports
    ZDB-ID 603113-4
    ISSN 1879-114X ; 0149-2918
    ISSN (online) 1879-114X
    ISSN 0149-2918
    DOI 10.1016/j.clinthera.2020.07.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1435: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 404: Show issues

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  5. Article ; Online: Acute stroke care algorithm in a private tertiary hospital in the Philippines during the COVID-19 pandemic: A third world country experience.

    Co, Christian Oliver C / Yu, Jeryl Ritzi T / Macrohon-Valdez, Ma Cristina / Laxamana, Lina C / De Guzman, Vincent Paul E / Berroya-Moreno, Remy Margarette M / Mariano, Manuel M / Rivera, Peter Paul Dela Paz / Racpan-Cauntay, Joana Lyn M / Ilano, Karen Czarina S / Trias, Evita C / Domingo, Alyssa Mae C / Marcelo, Alvin Valeriano De Borja / Pineda-Franks, Maria Carissa C

    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association

    2020  Volume 29, Issue 9, Page(s) 105059

    Abstract: Background and purpose: Since the declaration of the Novel Coronavirus Disease (COVID-19) pandemic, ensuring the safety of our medical team while delivering timely management has been a challenge. Acute stroke patients continue to present to the ... ...

    Abstract Background and purpose: Since the declaration of the Novel Coronavirus Disease (COVID-19) pandemic, ensuring the safety of our medical team while delivering timely management has been a challenge. Acute stroke patients continue to present to the emergency department and they may not have the usual symptoms of COVID-19 infection. Stroke team response and management must be done within the shortest possible time to minimize worsening of the functional outcome without compromising safety of the medical team.
    Methods: Infection control recommendations, emergency department protocols and stroke response pathways utilized prior to the COVID 19 pandemic within our institution were evaluated by our stroke team in collaboration with the multidisciplinary healthcare services. Challenges during the COVID-19 scenario were identified, from which a revised acute stroke care algorithm was formulated to adapt to this pandemic.
    Results: We formulated an algorithm that incorporates practices from internationally devised protocols while tailoring certain aspects to suit the available resources in our system locally. We highlighted the significance of the following: team role designation, coordination among different subspecialties and departments, proper use of personal protective equipment and resources, and telemedicine use during this pandemic.
    Conclusions: This pandemic has shaped the stroke team's approach in the management of acute stroke patients. Our algorithm ensures proper resource management while optimizing acute stroke care during the COVID-19 pandemic in our local setting. This algorithm may be utilized and adapted for local practice and other third world countries who face similar constraints.
    MeSH term(s) Algorithms ; COVID-19 ; Cooperative Behavior ; Coronavirus Infections/diagnosis ; Coronavirus Infections/epidemiology ; Coronavirus Infections/therapy ; Coronavirus Infections/transmission ; Critical Pathways/organization & administration ; Delivery of Health Care, Integrated/organization & administration ; Developing Countries ; Hospitals, Private/organization & administration ; Humans ; Infection Control/organization & administration ; Interdisciplinary Communication ; Occupational Health ; Pandemics ; Patient Care Team/organization & administration ; Patient Safety ; Philippines/epidemiology ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/therapy ; Pneumonia, Viral/transmission ; Risk Factors ; Stroke/diagnosis ; Stroke/epidemiology ; Stroke/therapy ; Tertiary Care Centers/organization & administration ; Treatment Outcome ; Workflow
    Keywords covid19
    Language English
    Publishing date 2020-06-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1131675-5
    ISSN 1532-8511 ; 1052-3057
    ISSN (online) 1532-8511
    ISSN 1052-3057
    DOI 10.1016/j.jstrokecerebrovasdis.2020.105059
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3519: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

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  6. Article: Acute stroke care algorithm in a private tertiary hospital in the Philippines during the COVID-19 pandemic: A third world country experience

    Co, Christian Oliver C / Yu, Jeryl Ritzi T / Macrohon-Valdez, Ma Cristina / Laxamana, Lina C / De Guzman, Vincent Paul E / Berroya-Moreno, Remy Margarette M / Mariano, Manuel M / Rivera, Peter Paul Dela Paz / Racpan-Cauntay, Joana Lyn M / Ilano, Karen Czarina S / Trias, Evita C / Domingo, Alyssa Mae C / Marcelo, Alvin Valeriano De Borja / Pineda-Franks, Maria Carissa C

    J Stroke Cerebrovasc Dis

    Abstract: BACKGROUND AND PURPOSE: Since the declaration of the Novel Coronavirus Disease (COVID-19) pandemic, ensuring the safety of our medical team while delivering timely management has been a challenge. Acute stroke patients continue to present to the ... ...

    Abstract BACKGROUND AND PURPOSE: Since the declaration of the Novel Coronavirus Disease (COVID-19) pandemic, ensuring the safety of our medical team while delivering timely management has been a challenge. Acute stroke patients continue to present to the emergency department and they may not have the usual symptoms of COVID-19 infection. Stroke team response and management must be done within the shortest possible time to minimize worsening of the functional outcome without compromising safety of the medical team. METHODS: Infection control recommendations, emergency department protocols and stroke response pathways utilized prior to the COVID 19 pandemic within our institution were evaluated by our stroke team in collaboration with the multidisciplinary healthcare services. Challenges during the COVID-19 scenario were identified, from which a revised acute stroke care algorithm was formulated to adapt to this pandemic. RESULTS: We formulated an algorithm that incorporates practices from internationally devised protocols while tailoring certain aspects to suit the available resources in our system locally. We highlighted the significance of the following: team role designation, coordination among different subspecialties and departments, proper use of personal protective equipment and resources, and telemedicine use during this pandemic. CONCLUSIONS: This pandemic has shaped the stroke team's approach in the management of acute stroke patients. Our algorithm ensures proper resource management while optimizing acute stroke care during the COVID-19 pandemic in our local setting. This algorithm may be utilized and adapted for local practice and other third world countries who face similar constraints.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #609437
    Database COVID19

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    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  7. Article ; Online: Acute stroke care algorithm in a private tertiary hospital in the Philippines during the COVID-19 pandemic

    Co, Christian Oliver C. / Yu, Jeryl Ritzi T. / Macrohon-Valdez, Ma. Cristina / Laxamana, Lina C. / De Guzman, Vincent Paul E. / Berroya-Moreno, Remy Margarette M. / Mariano, Manuel M. / Rivera, Peter Paul Dela Paz / Racpan-Cauntay, Joana Lyn M. / Ilano, Karen Czarina S. / Trias, Evita C. / Domingo, Alyssa Mae C. / Marcelo, Alvin Valeriano De Borja / Pineda-Franks, Maria Carissa C.

    Journal of Stroke and Cerebrovascular Diseases

    A third world country experience

    2020  Volume 29, Issue 9, Page(s) 105059

    Keywords Surgery ; Rehabilitation ; Clinical Neurology ; Cardiology and Cardiovascular Medicine ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 1131675-5
    ISSN 1052-3057
    ISSN 1052-3057
    DOI 10.1016/j.jstrokecerebrovasdis.2020.105059
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3519: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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