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  1. Article: The Reflux and BariClip: Initial Results and Mechanism of Action.

    Noel, Patrick / Layani, Laurent / Manos, Thierry / Adala, Mourad / Carandina, Sergio / Nedelcu, Anamaria / Nedelcu, Marius

    Journal of clinical medicine

    2022  Volume 11, Issue 22

    Abstract: Introduction: Laparoscopic BariClip Gastroplasty (LBCG) represents a new bariatric procedure that mimics the principle of the Laparoscopic Sleeve Gastrectomy (LSG), but using a completely reversible mechanism, which is essential for gastroesophageal ... ...

    Abstract Introduction: Laparoscopic BariClip Gastroplasty (LBCG) represents a new bariatric procedure that mimics the principle of the Laparoscopic Sleeve Gastrectomy (LSG), but using a completely reversible mechanism, which is essential for gastroesophageal reflux disease (GERD). The purpose of our study was to evaluate the evolution of GERD following the initial experience with LBCG.
    Methods: The first 43 obese patients who underwent LBCG performed by the same surgeon in two different medical centers in May 2018-December 2019 were included in the current study. Twelve patients had issues of reflux, regularly receiving PPIs (proton pump inhibitors) treatment in eight cases, and occasionally in four cases. Thirty-two patients completed the follow-up at one year and the GERD was evaluated using the PPI medications and the GerdQ.
    Results: The median preoperative GerdQ score was (14.58 ± 1.9). Three patients out of the twelve who had complained about preoperative GERD did not consent to the one year follow-up form. For the rest of nine patients, the median post-operative GerdQ score was (10.11 ± 3.2). The PPIs were used at one year follow-up in six patients: four with occasional use, one patient with regular use showing no improvement, and one who experienced de novo GERD symptomatology (3.1%). No statistically significant difference between the groups was recorded in terms of GERD. We recorded no intraoperative complications. No case of erosion occurred in the post-operative period, but we encountered two cases of slippage. One additional BariClip was removed at 14 months.
    Conclusion: LBCG represents a new bariatric procedure that mimics the principle of the laparoscopic sleeve gastrectomy, but with a completely reversible mechanism. Even with limited cases, our experience reports several mechanisms of action that will be evaluated and discussed in further prospective clinical trials. After this preliminary clinical study, LBCG's effects on GERD and its safety are highly encouraging.
    Language English
    Publishing date 2022-11-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm11226698
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Technical Variations and Considerations around OAGB in IFSO-APC and IFSO-MENAC Chapters, an Expert Survey.

    Kermansaravi, Mohammad / Shahmiri, Shahab Shahabi / Kow, Lilian / Gawdat, Khaled / Abbas, Syed Imran / Aly, Ahmad / Bashir, Ahmad / Bhandari, Mohit / Haddad, Ashraf / ElFawal, Mohamad Hayssam / Inam, Atif / Kasama, Kazunori / Kim, Sang Hyun / Kular, Kuldeepak Singh / Lakdawala, Muffazal / Layani, Laurent Abram / Lee, Wei-Jei / Pazouki, Abdolreza / Prasad, Arun /
    Safadi, Bassem / Wang, Cunchuan / Yang, Wah / Adib, Reza / Jazi, Amir Hossein Davarpanah / Shabbir, Asim

    Obesity surgery

    2024  

    Abstract: Objective: This study aimed to evaluate the technical variations of one-anastomosis gastric bypass (OAGB) among IFSO-APC and MENAC experts.: Background: The multitude of technical variations and patient selection challenges among metabolic and ... ...

    Abstract Objective: This study aimed to evaluate the technical variations of one-anastomosis gastric bypass (OAGB) among IFSO-APC and MENAC experts.
    Background: The multitude of technical variations and patient selection challenges among metabolic and bariatric surgeons worldwide necessitates a heightened awareness of these issues. Understanding different perspectives and viewpoints can empower surgeons performing OAGB to adapt their techniques, leading to improved outcomes and reduced complications.
    Methods: The scientific team of IFSO-APC, consisting of skilled bariatric and metabolic surgeons specializing in OAGB, conducted a confidential online survey. The survey aimed to assess technical variations and considerations related to OAGB within the IFSO-APC and IFSO-MENAC chapters. A total of 85 OAGB experts participated in the survey, providing their responses through a 35-question online format. The survey took place from January 1, 2024, to February 15, 2024.
    Results: Most experts do not perform OAGB for children and adolescents younger than 18 years. Most experts create the gastric pouch over a 36-40-F bougie and prefer to create a gastrojejunostomy, at the posterior wall of the gastric pouch. An anti-reflux suture during OAGB is performed in all patients by 51.8% of experts. Most experts set a common limb length of > 4 m in revisional and conversional OAGBs to prevent nutritional complications.
    Conclusion: The ongoing debate among metabolic and bariatric surgeons regarding the technical variations and patient selection in OAGB remains a significant point of discussion. This survey demonstrated the variations in technical aspects and patient selection for OAGB among MBS surgeons in the IFSO-APC and IFSO-MENAC chapters. Standardizing the OAGB technique is crucial to ensure optimal safety and efficacy in this procedure.
    Language English
    Publishing date 2024-04-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1070827-3
    ISSN 1708-0428 ; 0960-8923
    ISSN (online) 1708-0428
    ISSN 0960-8923
    DOI 10.1007/s11695-024-07239-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Efficacy of bariatric surgery in improving metabolic outcomes in patients with diabetes. A 24-month follow-up study from a single center in the UAE.

    Alnageeb, Hanadi / Abdelgadir, Elamin / Khalifa, Azza / Suliman, Mohamed / Gautam, Subash Chander / Layani, Laurent / Subramaniam, Sriganesh / Bashier, Alaaeldin

    Diabetes, metabolic syndrome and obesity : targets and therapy

    2018  Volume 11, Page(s) 459–467

    Abstract: Background: Owing to its impact on weight loss, remission of diabetes mellitus and metabolic syndrome, bariatric surgery has offered hope for grossly obese individuals. In recent years, obesity has increased in the UAE and the use of bariatric surgery ... ...

    Abstract Background: Owing to its impact on weight loss, remission of diabetes mellitus and metabolic syndrome, bariatric surgery has offered hope for grossly obese individuals. In recent years, obesity has increased in the UAE and the use of bariatric surgery has increased in-line with this trend. However, data regarding bariatric surgery outcomes in diabetic Emirati people is scarce.
    Objective: To evaluate the effect of bariatric surgery in patients with diabetes mellitus.
    Methods: This is a retrospective analysis of diabetic patients treated with bariatric surgery with a minimal follow-up of 1 year and extended for some patients (21) to 2 years follow up. A total of 80 patients underwent bariatric surgery. Two surgical procedures were used; laparoscopic sleeve gastrectomy (n=53) or mini-gastric bypass between January 1, 2015, and July 20, 2017.
    Results: Mean baseline weight was 119.2±31.2 kg, this has significantly dropped to 100.1±23.1, 91.2±22.3, 82.3±17.5, and 81.3±15.3 kg at 3, 6, 12, and 24 months respectively, and this change was statistically significant
    Conclusions: Bariatric surgery was effective over a follow-up period of 2 years in achieving significant weight loss as well as resulting in improvements in glycemic control, blood pressure, and fatty liver.
    Language English
    Publishing date 2018-09-03
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2494854-8
    ISSN 1178-7007
    ISSN 1178-7007
    DOI 10.2147/DMSO.S176761
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Laparoscopic adjustable gastric banding in patients > or =60 years old: is it worthwhile?

    Taylor, Craig John / Layani, Laurent

    Obesity surgery

    2006  Volume 16, Issue 12, Page(s) 1579–1583

    Abstract: Background: Laparoscopic adjustable gastric banding (LAGB) is an effective treatment for morbid obesity in younger patients, leading to improvements in related co-morbidities and quality of life. Currently, little is known how these improvements apply ... ...

    Abstract Background: Laparoscopic adjustable gastric banding (LAGB) is an effective treatment for morbid obesity in younger patients, leading to improvements in related co-morbidities and quality of life. Currently, little is known how these improvements apply to older patients.
    Methods: A prospective review was conducted of patients > or =60 years old undergoing LAGB. Weight loss, complications, changes in Short Form-36 (SF-36) scores, and a comprehensive post-operative co-morbidity, medication and quality of life questionnaire were used to assess performance.
    Results: 40 patients with mean age 65.8 years (range 60-72) and preoperative mean BMI of 42.2 kg/m(2) (range 33-54) underwent LAGB from February 2000 to September 2005. Mean excess weight lost at 2 years was 54%. 3 complications (7.5%) occurred (1 slippage and 2 access-port infections). There were no perforations, erosions or deaths. After a mean postoperative interval of 27 months, SF-36 scores improved significantly in 4 of 8 components and exceeded age-matched population controls in 3 components. Co-morbidity improvement was reported in 80% of patients with diabetes, 79% with dyslipidemia, 75% with obstructive sleep apnea, 72% with heartburn, 69% with hypertension, 60% with musculoskeletal pain, and 56% with anxiety/depression. Medication requirements reduced or ceased in 66% who required musculoskeletal analgesics, 43% of diabetics, 33% using bronchodilators, and 29% with hypertension. Sleep improved in 48%, self-esteem increased in 70%, and 72% had a better outlook on life. 82% were happy that they had undergone LAGB, and 91% would recommend LAGB to other older people.
    Conclusion: LAGB offers safe and effective weight loss, and improvement in co-morbidities and in quality of life in morbidly obese patients aged > or =60 years.
    MeSH term(s) Age Factors ; Aged ; Cohort Studies ; Comorbidity ; Female ; Gastroplasty/adverse effects ; Gastroplasty/methods ; Humans ; Male ; Middle Aged ; Obesity, Morbid/complications ; Obesity, Morbid/psychology ; Obesity, Morbid/surgery ; Postoperative Complications/epidemiology ; Quality of Life ; Risk Factors ; Safety ; Time Factors ; Treatment Outcome ; Weight Loss
    Language English
    Publishing date 2006-12
    Publishing country United States
    Document type Journal Article ; Meta-Analysis
    ZDB-ID 1070827-3
    ISSN 1708-0428 ; 0960-8923
    ISSN (online) 1708-0428
    ISSN 0960-8923
    DOI 10.1381/096089206779319310
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Laparoscopic gastric banding in over 60s.

    Clough, Anthony / Layani, Laurent / Shah, Abha / Wheatley, Lucas / Taylor, Craig

    Obesity surgery

    2010  Volume 21, Issue 1, Page(s) 10–17

    Abstract: Background: The aggressive pursuit of weight loss in the elderly remains a controversial objective. In this series of 113 patients over 60 years of age who underwent laparoscopic gastric banding surgery, we report on complications, co-morbidity change, ... ...

    Abstract Background: The aggressive pursuit of weight loss in the elderly remains a controversial objective. In this series of 113 patients over 60 years of age who underwent laparoscopic gastric banding surgery, we report on complications, co-morbidity change, quality-of-life improvement and changes in medication use over a median follow-up period of 25.5 months.
    Methods: A prospectively kept database was reviewed from January 1999 to September 2008 identifying patients over 60 who underwent gastric banding surgery. Baseline and follow-up SF-36® survey scores were compared longitudinally. Co-morbidity change and medication use were assessed by questionnaire and electronic record review.
    Results: Major complications were experienced by 7.1% over the follow-up period with a re-operation rate of 15.0%. Excess BMI loss was 44.1% after 5 years and combined mean SF-36® quality-of-life scores (out of 100) improved 22.1 points, achieving parity with age-matched norms for the general population. Diabetes improved in 74.2% with hypertension, hyperlipidaemia and depression improving in 57.1, 51.1 and 35.9% of cases. A significant drop in medication use was not seen, and cancer was responsible for three deaths over the follow-up period. No surgical mortality was incurred.
    Conclusion: Laparoscopic gastric banding can markedly improve quality of life for morbidly obese over 60s. Health gains are significant, but medication use is not substantially altered. Gastric banding is an ideal weight loss operation for this age group due to its safety and efficacy, and the primary goal should be quality-of-life improvement.
    MeSH term(s) Age Factors ; Aged ; Female ; Gastroplasty ; Humans ; Laparoscopy ; Male ; Middle Aged ; Obesity, Morbid/surgery ; Quality of Life ; Weight Loss
    Language English
    Publishing date 2010-05-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1070827-3
    ISSN 1708-0428 ; 0960-8923
    ISSN (online) 1708-0428
    ISSN 0960-8923
    DOI 10.1007/s11695-010-0158-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Subfascial port placement in gastric banding surgery.

    Clough, Anthony / Layani, Laurent / Sidhu, Mayenaaz / Wheatley, Lucas / Shah, Abha

    Obesity surgery

    2009  Volume 21, Issue 5, Page(s) 604–608

    Abstract: Background: In some bariatric patients with predominantly intra-abdominal fat a shallow fat layer separates the gastric band access port from the skin. We hypothesise that subfascial port placement in these patients reduces skin erosions and port ... ...

    Abstract Background: In some bariatric patients with predominantly intra-abdominal fat a shallow fat layer separates the gastric band access port from the skin. We hypothesise that subfascial port placement in these patients reduces skin erosions and port infections and improves cosmesis as weight loss occurs.
    Aim: This study aims to compare port complications, cosmetic outcome and ease of band adjustment with access ports in front of or behind the rectus muscle.
    Method: We retrospectively compared complications and cosmetic outcomes of patients with subfascial ports to a control group matched for gender, BMI and age. Each subject completed a questionnaire utilising a 1 to 10 scale for nine parameters related to comfort and cosmesis and two parameters related to discomfort during adjustments.
    Results: Sixty-eight patients with subfascial ports were identified and the overall response rate was 84%. The groups were well matched for gender (m:f ratio 1.8:1 vs. 1.7:1, p = 1.000), age (51.0 vs. 49.6 years, p = 0.528) and BMI (39.8 vs. 40.3 kg/m², p = 0.585). There was no difference in port infection rates (0/68 vs. 1/68, p = 1.000) but the subfascial group had more hernias (3/68 vs. 0/68, p = 0.244). Subfascial patients experienced more pain during adjustments (score 4.3 vs. 2.6, p = 0.047) but a combined analysis of cosmesis showed a slight positive trend (1.58 vs. 1.76, p = 0.379).
    Conclusion: Both port locations are well tolerated. Subfascial placement is associated with more pain during adjustments but there is no difference in port infection or skin erosion rates.
    MeSH term(s) Female ; Gastroplasty/adverse effects ; Gastroplasty/methods ; Humans ; Male ; Middle Aged ; Postoperative Complications/epidemiology ; Retrospective Studies
    Language English
    Publishing date 2009-08-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1070827-3
    ISSN 1708-0428 ; 0960-8923
    ISSN (online) 1708-0428
    ISSN 0960-8923
    DOI 10.1007/s11695-009-9931-6
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  7. Article: Laparoscopic gastric resection for benign and malignant conditions: lessons learned from 35 consecutive cases.

    Liew, Victor / Taylor, Craig / Ghusn, Michael / Jamnagerwalla, Murtaza / Layani, Laurent

    ANZ journal of surgery

    2007  Volume 77, Issue 9, Page(s) 787–791

    Abstract: Introduction: Despite significant advances in laparoscopy, gastric surgery is still generally carried out by conventional open techniques. The aim of the study was to report the short- and medium-term outcomes of gastric surgery when carried out ... ...

    Abstract Introduction: Despite significant advances in laparoscopy, gastric surgery is still generally carried out by conventional open techniques. The aim of the study was to report the short- and medium-term outcomes of gastric surgery when carried out laparoscopically for a variety of benign and malignant conditions.
    Methods: A retrospective review was carried out for all patients who underwent a laparoscopic gastric resection between January 2000 and September 2006. Follow up was carried out at the private consulting rooms and by telephone interview.
    Results: Thirty-five consecutive laparoscopic gastric resection were carried out in 31 patients for a variety of benign lesions, six early gastric cancer and 13 adenocarcinomas. The totally intracorporeal laparoscopic procedures included four total, eight distal and 21 partial gastrectomies. There were two open conversions (6%). There was one in-hospital mortality (3%) and one non-fatal anastomotic leak. Median operative duration and length of stay were 75, 205 and 252 min and 5, 6.5 and 8 days for laparoscopic partial, distal and total gastrectomy, respectively. After malignant resections, there were six recurrences; however, 15 patients remained disease-free at up to 60 months follow up.
    Conclusion: Laparoscopic gastric resection is feasible with good short- and medium-term results and may be an appropriate treatment option in selected cases.
    MeSH term(s) Adenocarcinoma/surgery ; Aged ; Aged, 80 and over ; Feasibility Studies ; Female ; Gastrectomy ; Humans ; Laparoscopy ; Male ; Middle Aged ; Retrospective Studies ; Stomach Diseases/surgery ; Stomach Neoplasms/surgery ; Treatment Outcome
    Language English
    Publishing date 2007-09
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2050749-5
    ISSN 1445-2197 ; 1445-1433 ; 0004-8682
    ISSN (online) 1445-2197
    ISSN 1445-1433 ; 0004-8682
    DOI 10.1111/j.1445-2197.2007.04224.x
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  8. Article: Perforated diverticulitis managed by laparoscopic lavage.

    Taylor, Craig J / Layani, Laurent / Ghusn, Michael A / White, Stephen I

    ANZ journal of surgery

    2006  Volume 76, Issue 11, Page(s) 962–965

    Abstract: Background: Traditionally the management of acute diverticulitis complicated by perforation has been the Hartmann's procedure, which may be associated with significant morbidity and mortality and the unpleasantness of a colostomy. We present our early ... ...

    Abstract Background: Traditionally the management of acute diverticulitis complicated by perforation has been the Hartmann's procedure, which may be associated with significant morbidity and mortality and the unpleasantness of a colostomy. We present our early experience in managing perforated diverticulitis acutely by laparoscopic lavage and drainage.
    Methods: A retrospective review was conducted of all patients with surgically confirmed perforated diverticulitis. Details concerning the nature of presentation, operative findings, postoperative course and medium-term progress were investigated.
    Results: Fourteen patients with a mean age of 57.2 years were identified over a 3-year period. All patients presented with peritonitis and systemic sepsis. Ten patients had extraluminal gas on preoperative imaging. Laparoscopic lavage and drainage, without resection or stoma, was the initial management in all cases. Sigmoid diverticulitis was confirmed in all cases, complicated by Hinchey grade 3 purulent peritonitis in 10 patients, grade 2 contamination in 2 patients and grade 4 faeculent peritonitis in 2 patients. Eleven patients (79%) improved and were discharged following a median of 6.5 days (range, 5-32 days). Three patients did not improve and underwent acute resection. Eight patients have subsequently undergone elective resection without a stoma at a mean interval of 6 weeks, which was carried out laparoscopically in all but one case.
    Conclusion: Laparoscopic lavage and drainage in the acute management of perforated acute diverticulitis may be a promising alternative to more radical procedures, including the Hartmann's procedure. Acute resection should still be carried out in patients found to have faecal peritonitis or who fail to improve following lavage.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Diverticulitis, Colonic/therapy ; Female ; Follow-Up Studies ; Humans ; Laparoscopy ; Male ; Middle Aged ; Peritoneal Lavage/methods ; Retrospective Studies ; Rupture, Spontaneous ; Sigmoid Diseases/therapy ; Treatment Outcome
    Language English
    Publishing date 2006-11
    Publishing country Australia
    Document type Journal Article ; Multicenter Study
    ZDB-ID 2050749-5
    ISSN 1445-2197 ; 1445-1433 ; 0004-8682
    ISSN (online) 1445-2197
    ISSN 1445-1433 ; 0004-8682
    DOI 10.1111/j.1445-2197.2006.03908.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Laparoscopic inguinal hernia repair without mesh fixation, early results of a large randomised clinical trial.

    Taylor, Craig / Layani, Laurent / Liew, Victor / Ghusn, Michael / Crampton, Nic / White, Stephen

    Surgical endoscopy

    2008  Volume 22, Issue 3, Page(s) 757–762

    Abstract: Background: A new persistent groin pain is reported by a significant number of patients following laparoscopic totally extraperitoneal hernia repair (TEP). Mesh fixation has been implicated as a possible cause, but is widely considered essential for ... ...

    Abstract Background: A new persistent groin pain is reported by a significant number of patients following laparoscopic totally extraperitoneal hernia repair (TEP). Mesh fixation has been implicated as a possible cause, but is widely considered essential for mesh stabilization and early recurrence prevention. This study investigates whether any association exists between mesh fixation by metal tacks and the incidence of new groin pain or early hernia recurrence.
    Methods: A prospective multicenter double-blinded randomised trial was conducted between December 2004 and January 2006. Standardized TEP repair was performed with a rectangular 10 x 15cm polypropylene mesh. Hernia were randomized to either mesh fixation by metal tacks or left entirely unfixated. Clinical review by physical examination was performed by a separate blinded surgeon after a minimum of six months, with another review planned after two years. The incidence of new groin pain and recurrence were compared.
    Results: Five hundred herniae in 360 patients were entered into the study. At the first wave of clinical follow-up (median eight, range 6-13 postoperative months) a new pain was reported by 38 versus 23% (p = 0.003), occurring at least once a week in 22 versus 15% (p = 0.049), or several times per week in 16 versus 8% (p = 0.009) for fixated versus unfixated repairs, respectively. Patients with bilateral repairs were five times more likely to report the unfixated side being more comfortable (p = 0.006). There was one recurrence in the fixated group (1/247) whilst none have yet occurred in the unfixated group. Fixation increased operative costs by approximately 375 AUD.
    Conclusion: Mesh fixation in TEP is associated with increased operative cost and chronic pain but no difference in the risk of hernia recurrence at six months was observed.
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Double-Blind Method ; Female ; Follow-Up Studies ; Hernia, Inguinal/diagnosis ; Hernia, Inguinal/surgery ; Humans ; Laparoscopy/adverse effects ; Laparoscopy/methods ; Male ; Middle Aged ; Pain Measurement ; Pain, Postoperative/physiopathology ; Postoperative Complications/physiopathology ; Probability ; Prospective Studies ; Risk Assessment ; Secondary Prevention ; Sensitivity and Specificity ; Severity of Illness Index ; Surgical Mesh ; Wound Healing/physiology
    Language English
    Publishing date 2008-03
    Publishing country Germany
    Document type Journal Article ; Multicenter Study ; Randomized Controlled Trial
    ZDB-ID 639039-0
    ISSN 1432-2218 ; 0930-2794
    ISSN (online) 1432-2218
    ISSN 0930-2794
    DOI 10.1007/s00464-007-9510-7
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  10. Article: Laparoscopic bile duct exploration: results of 160 consecutive cases with 2-year follow up.

    Taylor, Craig J / Kong, Justin / Ghusn, Michael / White, Stephen / Crampton, Nick / Layani, Laurent

    ANZ journal of surgery

    2007  Volume 77, Issue 6, Page(s) 440–445

    Abstract: Background: Despite numerous reports showing the advantages of laparoscopic common bile duct exploration (LCBDE), many general surgeons, particularly those working outside of nonspecialist units, continue to rely heavily on endoscopic retrograde ... ...

    Abstract Background: Despite numerous reports showing the advantages of laparoscopic common bile duct exploration (LCBDE), many general surgeons, particularly those working outside of nonspecialist units, continue to rely heavily on endoscopic retrograde cholangiography with sphincterotomy (ERCP) to manage bile duct stones (BDS). This article investigates the performance of LCBDE when adopted as the preferred first-line management of both suspected and incidental BDS by general surgeons in a regional setting.
    Methods: A retrospective review was conducted of all patients in whom LCBDE was attempted by a regional general surgical unit. The unit policy was to preferentially treat all incidental and suspected BDS (except in ascending cholangitis or severe pancreatitis) by LCBDE, with ERCP used only if unsuccessful. In addition to chart review, formal prospective follow up by telephone interview was carried out.
    Results: A total of 160 consecutive patients with BDS (mean age 66.9 years, 65% suspected and 35% incidental) underwent attempted LCBDE between January 2000 and July 2005. Successful clearance was achieved in 84.3% according to chart review. However, four additional cases of retained choledocholithiasis shown by late telephone interview (median interval 2.5 years) yielded a more accurate clearance rate of 81.8%. Major morbidity occurred in 13.8%, including biliary leak in 7.5% and one late biliary stricture (0.6%). Median length of hospital stay was 4.8 days. In-hospital mortality was 0.6%.
    Conclusion: Laparoscopic common bile duct exploration remains an effective, efficient and safe first-line treatment of BDS even when carried out in regional nonspecialist units. In spite of the wide availability of ERCP, general surgeons should be encouraged to continue performing LCBDE in order to optimise patient care and maintain important surgical skills.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Common Bile Duct/surgery ; Female ; Follow-Up Studies ; Gallstones/mortality ; Gallstones/surgery ; Humans ; Laparoscopy ; Length of Stay ; Male ; Middle Aged ; Postoperative Complications ; Retrospective Studies ; Treatment Outcome
    Language English
    Publishing date 2007-06
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2050749-5
    ISSN 1445-2197 ; 1445-1433 ; 0004-8682
    ISSN (online) 1445-2197
    ISSN 1445-1433 ; 0004-8682
    DOI 10.1111/j.1445-2197.2007.04091.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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