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  1. Article ; Online: Reply to Drs Guimarães de Oliveira and de Andrade Chaves.

    Bravo, Daniela / Aliste, Julián / Layera, Sebastián / Tran, De Q

    Regional anesthesia and pain medicine

    2023  Volume 48, Issue 11, Page(s) 578–579

    Language English
    Publishing date 2023-03-28
    Publishing country England
    Document type Letter
    ZDB-ID 1425299-5
    ISSN 1532-8651 ; 1098-7339 ; 0146-521X
    ISSN (online) 1532-8651
    ISSN 1098-7339 ; 0146-521X
    DOI 10.1136/rapm-2023-104522
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Accurately determining accuracy.

    Aliste, Julián / Bravo, Daniela / Layera, Sebastián

    Minerva anestesiologica

    2019  Volume 86, Issue 1, Page(s) 96–97

    MeSH term(s) Central Nervous System ; Epidural Space ; Female ; Humans ; Labor, Obstetric ; Pregnancy
    Language English
    Publishing date 2019-06-20
    Publishing country Italy
    Document type Letter ; Comment
    ZDB-ID 123584-9
    ISSN 1827-1596 ; 0026-4717 ; 0375-9393
    ISSN (online) 1827-1596
    ISSN 0026-4717 ; 0375-9393
    DOI 10.23736/S0375-9393.19.13836-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Motor-Sparing Peripheral Nerve Blocks for Shoulder, Knee, and Hip Surgery.

    Layera, Sebastián / Saadawi, Mohammed / Tran, De Q / Salinas, Francis V

    Advances in anesthesia

    2020  Volume 38, Page(s) 189–207

    MeSH term(s) Hip Joint/surgery ; Humans ; Knee Joint/surgery ; Nerve Block/methods ; Shoulder Joint/surgery
    Language English
    Publishing date 2020-10-01
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 632613-4
    ISSN 1878-0415 ; 0737-6146
    ISSN (online) 1878-0415
    ISSN 0737-6146
    DOI 10.1016/j.aan.2020.08.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Existing evidence and logical lapsus.

    Aliste, Julián / Layera, Sebastián / Bravo, Daniela / Akarapatima, Raviwan / Tran, De Q

    Regional anesthesia and pain medicine

    2021  Volume 46, Issue 5, Page(s) 464–465

    Language English
    Publishing date 2021-02-08
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 1425299-5
    ISSN 1532-8651 ; 1098-7339 ; 0146-521X
    ISSN (online) 1532-8651
    ISSN 1098-7339 ; 0146-521X
    DOI 10.1136/rapm-2021-102464
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Randomized comparison between perineural dexamethasone and combined perineural dexamethasone-dexmedetomidine for ultrasound-guided infraclavicular block.

    Aliste, Julián / Layera, Sebastián / Bravo, Daniela / Aguilera, Germán / Erpel, Hans / García, Armando / Lizama, Marcelo / Finlayson, Roderick J / Tran, D

    Regional anesthesia and pain medicine

    2022  

    Abstract: Background: This randomized trial compared perineural dexamethasone with combined perineural dexamethasone-dexmedetomidine for ultrasound-guided infraclavicular block. We hypothesized that the combination of perineural adjuvants would result in a longer ...

    Abstract Background: This randomized trial compared perineural dexamethasone with combined perineural dexamethasone-dexmedetomidine for ultrasound-guided infraclavicular block. We hypothesized that the combination of perineural adjuvants would result in a longer motor block.
    Methods: Fifty patients undergoing upper limb surgery with ultrasound-guided infraclavicular block (using 35 mL of lidocaine 1%-bupivacaine 0.25% with epinephrine 5 µg/mL) were randomly allocated to receive perineural dexamethasone (2 mg) or combined perineural dexamethasone (2 mg)-dexmedetomidine (50 µg). After the performance of the block, a blinded observer assessed the success rate (defined as a minimal sensorimotor composite score of 14 out of 16 points at 30 min), the onset time (defined as the time required to reach a minimal composite score of 14 points) as well as the incidence of surgical anesthesia (defined as the ability to complete surgery without local infiltration, supplemental blocks, intravenous opioids or general anesthesia).Postoperatively, the blinded observer contacted patients with successful blocks to inquire about the duration of motor block, sensory block and postoperative analgesia.
    Results: No intergroup differences were observed in terms of success rate, onset time and surgical anesthesia. Compared with dexamethasone alone, combined dexamethasone-dexmedetomidine provided longer durations of motor block (21.5 (2.7) vs 17.0 (3.9) hours; p<0.001; 95% CI 2.6 to 6.4), sensory block (21.6 (3.6) vs 17.2 (3.6) hours; p<0.001; 95% CI 2.2 to 6.5), and postoperative analgesia (25.5 (9.4) vs 23.5 (5.6) hours; p=0.038; 95% CI 1.0 to 7.7).
    Conclusion: Compared with perineural dexamethasone (2 mg) alone, combined perineural dexamethasone (2 mg)-dexmedetomidine (50 µg) results in longer durations of sensorimotor block and analgesia. Further studies are required to determine the optimal dosing combination for dexamethasone-dexmedetomidine.
    Trial registration number: ClinicalTrials.gov identifier: NCT04875039.
    Language English
    Publishing date 2022-06-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 1425299-5
    ISSN 1532-8651 ; 1098-7339 ; 0146-521X
    ISSN (online) 1532-8651
    ISSN 1098-7339 ; 0146-521X
    DOI 10.1136/rapm-2022-103760
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Retroclavicular approach to infraclavicular brachial plexus block: a logical conundrum.

    Leurcharusmee, Prangmalee / Layera, Sebastián / Finlayson, Roderick J / Tran, De Q

    Regional anesthesia and pain medicine

    2019  

    Language English
    Publishing date 2019-01-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 1425299-5
    ISSN 1532-8651 ; 1098-7339 ; 0146-521X
    ISSN (online) 1532-8651
    ISSN 1098-7339 ; 0146-521X
    DOI 10.1136/rapm-2018-100133
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Slam dunk or air ball?

    Tran, De Q / Layera, Sebastián / Bravo, Daniela / Cristi-Sánchez, Iver / Bermúdez, Loreley / Aliste, Julián

    Regional anesthesia and pain medicine

    2020  Volume 46, Issue 3, Page(s) 288–289

    MeSH term(s) Brachial Plexus ; Brachial Plexus Block ; Humans
    Language English
    Publishing date 2020-05-30
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 1425299-5
    ISSN 1532-8651 ; 1098-7339 ; 0146-521X
    ISSN (online) 1532-8651
    ISSN 1098-7339 ; 0146-521X
    DOI 10.1136/rapm-2020-101650
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  8. Article ; Online: Diaphragm-sparing nerve blocks should spare the diaphragm.

    Tran, De Q / Layera, Sebastián / Bravo, Daniela / Cristi-Sánchez, Iver / Bermúdez, Loreley / Aliste, Julián

    Regional anesthesia and pain medicine

    2020  

    Language English
    Publishing date 2020-01-21
    Publishing country England
    Document type Letter
    ZDB-ID 1425299-5
    ISSN 1532-8651 ; 1098-7339 ; 0146-521X
    ISSN (online) 1532-8651
    ISSN 1098-7339 ; 0146-521X
    DOI 10.1136/rapm-2019-101259
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Erector spinae plane block: A narrative review with systematic analysis of the evidence pertaining to clinical indications and alternative truncal blocks.

    Saadawi, Mohammed / Layera, Sebastián / Aliste, Julián / Bravo, Daniela / Leurcharusmee, Prangmalee / Tran, De Q

    Journal of clinical anesthesia

    2020  Volume 68, Page(s) 110063

    Abstract: Study objective: This narrative review discusses the anatomy, mechanism of action, techniques, pharmacology, indications, complications and substitutes for erector spinae plane (ESP) blocks.: Interventions: The Medline, Embase and Google Scholar ... ...

    Abstract Study objective: This narrative review discusses the anatomy, mechanism of action, techniques, pharmacology, indications, complications and substitutes for erector spinae plane (ESP) blocks.
    Interventions: The Medline, Embase and Google Scholar databases (inception-last week of April 2020) were searched. For indications and alternative blocks, a systematic analysis of the available evidence was carried out. In order to highlight the best evidence available, only randomized trials with prospective registration, blinded assessment and sample size justification were retained for analysis.
    Main results: The collective body of anatomical studies suggests that ESP block may work through a combination of different mechanisms (e.g., local anesthetic spread to the thoracic paravertebral space, epidural space, and dorsal ramus). Compared to control, the available evidence suggests that ESP block results in decreased postoperative pain and opioid requirement for a wide array of thoracic and abdominal surgical interventions. Erector spinae plane blocks and thoracic paravertebral blocks seem to provide comparable benefits for thoracoscopic and breast cancer surgery when performed with a similar number of injections. Currently, ESP blocks should be favored over intercostal blocks since, at best, the latter provide similar analgesia to ESP blocks despite requiring multiple-level injections.
    Conclusions: In recent years, ESP blocks have become the topic of considerable clinical interest. Future trials are required to investigate their optimal technique, dose of local anesthetic and perineural adjuvants. Moreover, additional investigation should compare ESP blocks with robust multimodal analgesic regimens as well as truncal blocks such as thoracic epidural block, midpoint transverse process to pleura block, PECS block, quadratus lumborum block, and transversus abdominis plane block.
    MeSH term(s) Anesthetics, Local ; Humans ; Nerve Block ; Pain, Postoperative/etiology ; Pain, Postoperative/prevention & control ; Paraspinal Muscles/diagnostic imaging ; Prospective Studies
    Chemical Substances Anesthetics, Local
    Language English
    Publishing date 2020-10-05
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1011618-7
    ISSN 1873-4529 ; 0952-8180
    ISSN (online) 1873-4529
    ISSN 0952-8180
    DOI 10.1016/j.jclinane.2020.110063
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  10. Article ; Online: Motor-sparing nerve blocks for total knee replacement: A scoping review.

    Layera, Sebastián / Aliste, Julián / Bravo, Daniela / Saadawi, Mohammed / Salinas, Francis V / Tran, De Q

    Journal of clinical anesthesia

    2020  Volume 68, Page(s) 110076

    Abstract: Study objective: This scoping review investigates the optimal combination of motor-sparing analgesic interventions for patients undergoing total knee replacement (TKR).: Design: Scoping review.: Intervention: MEDLINE, EMBASE and CINAHL databases ... ...

    Abstract Study objective: This scoping review investigates the optimal combination of motor-sparing analgesic interventions for patients undergoing total knee replacement (TKR).
    Design: Scoping review.
    Intervention: MEDLINE, EMBASE and CINAHL databases were searched (inception-last week of May 2020). Only trials including motor-sparing interventions were included. Randomized controlled trials lacking prospective registration and blinded assessment were excluded.
    Main results: The cumulative evidence suggests that femoral triangle blocks outperform placebo and periarticular infiltration. When combined with the latter, femoral triangle blocks are associated with improved pain control, higher patient satisfaction and decreased opioid consumption. Continuous femoral triangle blocks provide superior postoperative analgesia compared with their single-injection counterparts. However, these benefits seem less pronounced when perineural adjuvants are used. Combined femoral triangle-obturator blocks result in improved analgesia and swifter discharge compared with femoral triangle blocks alone.
    Conclusions: The optimal analgesic strategy for TKR may include a combination of different analgesic modalities (periarticular infiltration, femoral triangle blocks, obturator nerve block). Future trials are required to investigate the incremental benefits provided by local anesthetic infiltration between the popliteal artery and the capsule of the knee (IPACK), popliteal plexus block and genicular nerve block.
    MeSH term(s) Analgesia ; Anesthetics, Local ; Arthroplasty, Replacement, Knee/adverse effects ; Femoral Nerve ; Humans ; Nerve Block ; Pain, Postoperative/etiology ; Pain, Postoperative/prevention & control ; Prospective Studies
    Chemical Substances Anesthetics, Local
    Language English
    Publishing date 2020-10-06
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1011618-7
    ISSN 1873-4529 ; 0952-8180
    ISSN (online) 1873-4529
    ISSN 0952-8180
    DOI 10.1016/j.jclinane.2020.110076
    Database MEDical Literature Analysis and Retrieval System OnLINE

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