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Article ; Online: Correction to: "Dysphagia, dysphonia and olfactory disease: a map of Cochrane evidence relevant to rehabilitation for people with post-COVID-19 condition".

Cordani, Claudio / Battel, Irene / Del Furia, Matteo J / Lazzarini, Stefano G / Negrini, Stefano / Arienti, Chiara

European journal of physical and rehabilitation medicine

2024 Volume 60, Issue 1, Page(s) 164

Abstract: This article was published in volume 58, issue 6 of publishing year 2022, with a mistake in Table II. The correct Table II is the one included in this erratum. ...

Abstract	This article was published in volume 58, issue 6 of publishing year 2022, with a mistake in Table II. The correct Table II is the one included in this erratum.
Language	English
Publishing date	2024-02-27
Publishing country	Italy
Document type	Journal Article ; Published Erratum
ZDB-ID	2426908-6
ISSN	1973-9095 ; 1973-9087
ISSN (online)	1973-9095
ISSN	1973-9087
DOI	10.23736/S1973-9087.23.08368-5
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Article: The Efficacy of Electromagnetic Diathermy for the Treatment of Musculoskeletal Disorders: A Systematic Review with Meta-Analysis.

Pollet, Joel / Ranica, Giorgia / Pedersini, Paolo / Lazzarini, Stefano G / Pancera, Simone / Buraschi, Riccardo

Journal of clinical medicine

2023 Volume 12, Issue 12

Abstract: Objective: This study aims to establish the effect of electromagnetic diathermy therapies (e.g., shortwave, microwave, capacitive resistive electric transfer) on pain, function, and quality of life in treating musculoskeletal disorders.: Methods: We ... ...

Abstract	Objective: This study aims to establish the effect of electromagnetic diathermy therapies (e.g., shortwave, microwave, capacitive resistive electric transfer) on pain, function, and quality of life in treating musculoskeletal disorders. Methods: We conducted a systematic review according to the PRISMA statement and Cochrane Handbook 6.3. The protocol has been registered in PROSPERO: CRD42021239466. The search was conducted in PubMed, PEDro, CENTRAL, EMBASE, and CINAHL. Results: We retrieved 13,323 records; 68 studies were included. Many pathologies were treated with diathermy against placebo, as a standalone intervention or alongside other therapies. Most of the pooled studies did not show significant improvements in the primary outcomes. While the analysis of single studies shows several significant results in favour of diathermy, all comparisons considered had a GRADE quality of evidence between low and very low. Conclusions: The included studies show controversial results. Most of the pooled studies present very low quality of evidence and no significant results, while single studies have significant results with a slightly higher quality of evidence (low), highlighting a critical lack of evidence in the field. The results did not support the adoption of diathermy in a clinical context, preferring therapies supported by evidence.
Language	English
Publishing date	2023-06-09
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm12123956
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Rehabilitation and COVID-19: systematic review by Cochrane Rehabilitation.

Arienti, Chiara / Lazzarini, Stefano G / Andrenelli, Elisa / Cordani, Claudio / Negrini, Francesco / Pollini, Elisa / Ceravolo, Maria G

European journal of physical and rehabilitation medicine

2024 Volume 59, Issue 6, Page(s) 800–818

Abstract: Introduction: Until the last update in February 2022, the Cochrane Rehabilitation COVID-19 Evidence-based Response (REH-COVER) action identified an increasing volume of evidence for the rehabilitation management of COVID-19. Therefore, our aim was to ... ...

Abstract	Introduction: Until the last update in February 2022, the Cochrane Rehabilitation COVID-19 Evidence-based Response (REH-COVER) action identified an increasing volume of evidence for the rehabilitation management of COVID-19. Therefore, our aim was to identify the best available evidence on the effectiveness of interventions for rehabilitation for COVID-19-related limitations of functioning of rehabilitation interest in adults with COVID-19 or post COVID-19 condition (PCC). Evidence acquisition: We ran the searches on February 17 Evidence synthesis: After duplicate removal, we identified 18,950 individual records and 53 RCTs met the inclusion criteria. Our findings suggest that the effect of breathing and strengthening exercise programs on dyspnea and physical exercise capacity compared to no treatment in non-severe COVID-19 patients is uncertain. Multicomponent telerehabilitation may slightly increase physical exercise capacity compared to educational intervention in adults with PCC. There is, however, uncertainty about its effect on lung function and physical exercise capacity when compared to no treatment. Finally, the effect of inspiratory muscle training on maximal inspiratory pressure compared to no treatment in adults with PCC is uncertain. Conclusions: Interventions that are part of comprehensive pulmonary rehabilitation approaches may benefit dyspnea and exercise tolerance in adults with COVID-19 and PCC. The available evidence has several methodological limitations that limit the certainty of evidence and the clinical relevance of findings. Therefore, we cannot provide robust suggestions for practice. While high-quality RCTs are being conducted, clinicians should consider using high-quality evidence from other pulmonary conditions to rehabilitate patients with COVID-19 or PCC using context-specific interventions.
MeSH term(s)	Humans ; Chronic Disease ; COVID-19/epidemiology ; COVID-19/rehabilitation ; Dyspnea ; Exercise ; Physical Therapy Modalities
Language	English
Publishing date	2024-01-11
Publishing country	Italy
Document type	Systematic Review ; Journal Article
ZDB-ID	2426908-6
ISSN	1973-9095 ; 1973-9087
ISSN (online)	1973-9095
ISSN	1973-9087
DOI	10.23736/S1973-9087.23.08331-4
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Article ; Online: Dysphagia, dysphonia and olfactory disease: a map of Cochrane evidence relevant to rehabilitation for people with post COVID-19 condition.

Cordani, Claudio / Battel, Irene / Del Furia, Matteo J / Lazzarini, Stefano G / Negrini, Stefano / Arienti, Chiara

European journal of physical and rehabilitation medicine

2022 Volume 58, Issue 6, Page(s) 875–879

Abstract: Introduction: Currently, no evidence exists on specific treatments for post COVID-19 condition (PCC). However, rehabilitation interventions that proved effective for similar symptoms in other health conditions could be applied to people with PCC. With ... ...

Abstract	Introduction: Currently, no evidence exists on specific treatments for post COVID-19 condition (PCC). However, rehabilitation interventions that proved effective for similar symptoms in other health conditions could be applied to people with PCC. With this overview of systematic reviews with mapping, we aimed to describe the Cochrane evidence on rehabilitation interventions proposed for dysphagia, dysphonia and olfactory dysfunction in different health conditions that can be relevant for PCC. Evidence acquisition: We searched the last five years' Cochrane Systematic Review (CSRs) using the terms "dysphagia," "swallowing disorder," "dysphonia," "voice disorder," "olfactory dysfunction," "smell changes" and "rehabilitation" in the Cochrane Library. We extracted and summarized the available evidence using a map. We grouped the included CSRs for health conditions and interventions, indicating the effect and the quality of evidence. Evidence synthesis: We found 170 CSRs published between 2016 and 2021 and 1 was included. It provided data on dysphagia in acute and subacute stroke. Interventions included were acupuncture, neuromuscular electrical stimulation, transcranial magnetic stimulation and behavioral interventions, and swallowing therapy, with very low- to moderate-quality evidence. We did not find any CSR on dysphonia and olfactory disease. Conclusions: These results are the first step of indirect evidence able to generate helpful hypotheses for clinical practice and future research. They served as the basis for the three recommendations on treatments for these PCC symptoms published in the current WHO Guidelines for clinical practice.
MeSH term(s)	Humans ; COVID-19 ; Deglutition Disorders/etiology ; Deglutition Disorders/rehabilitation ; Dysphonia/etiology ; Olfaction Disorders/etiology ; Systematic Reviews as Topic
Language	English
Publishing date	2022-12-19
Publishing country	Italy
Document type	Journal Article ; Review
ZDB-ID	2426908-6
ISSN	1973-9095 ; 1973-9087
ISSN (online)	1973-9095
ISSN	1973-9087
DOI	10.23736/S1973-9087.22.07811-X
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Article ; Online: Rehabilitation and COVID-19: update of the rapid living systematic review by Cochrane Rehabilitation Field as of October 31st, 2021.

Andrenelli, Elisa / Negrini, Francesco / de Sire, Alessandro / Lazzarini, Stefano G / Patrini, Michele / Ceravolo, Maria G

European journal of physical and rehabilitation medicine

2022 Volume 58, Issue 1, Page(s) 153–156

MeSH term(s)	COVID-19/epidemiology ; Humans ; SARS-CoV-2 ; Systematic Reviews as Topic
Language	English
Publishing date	2022-03-01
Publishing country	Italy
Document type	Journal Article
ZDB-ID	2426908-6
ISSN	1973-9095 ; 1973-9087
ISSN (online)	1973-9095
ISSN	1973-9087
DOI	10.23736/S1973-9087.22.07434-2
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Article ; Online: Arthralgia: a map of Cochrane evidence relevant to rehabilitation for people with post COVID-19 condition.

Cordani, Claudio / Lazzarini, Stefano G / Del Furia, Matteo J / Kiekens, Carlotte / Arienti, Chiara / Negrini, Stefano

European journal of physical and rehabilitation medicine

2022 Volume 58, Issue 6, Page(s) 870–874

Abstract: Introduction: Rehabilitation focuses on impairments, activity limitations and participation restrictions being informed by the underlying health condition. In the current absence of direct "evidence on" rehabilitation interventions for people with post ... ...

Abstract	Introduction: Rehabilitation focuses on impairments, activity limitations and participation restrictions being informed by the underlying health condition. In the current absence of direct "evidence on" rehabilitation interventions for people with post COVID-19 condition (PCC), we can search and synthesize the indirect "evidence relevant to" coming from interventions effective on the symptoms of PCC in other health conditions. The World Health Organization (WHO) required this information to inform expert teams and provide specific recommendations in its Guidelines. With this overview of reviews with mapping we aimed to synthesize the Cochrane evidence relevant to rehabilitation for arthralgia due to PCC in a map. Evidence acquisition: We searched the last five years' Cochrane Systematic Review (CSRs) using the terms "arthralgia," "joint pain," and "rehabilitation" and their synonyms in the Cochrane Library. We extracted and summarized all the available evidence using a map. We grouped the included CSRs for health conditions and interventions, indicating the effect and the quality of evidence. Evidence synthesis: We found 200 CSRs published between 2016 and 2021, and included 11 in this overview. They provided data from 7 health conditions, with osteoarthritis (5 studies) being the most studied. Effective rehabilitation interventions included exercise training, transcranial magnetic stimulation, different types of electrical stimulation and Tai chi. The overall quality of evidence was mainly low to very low, and moderate in a few cases. Conclusions: These results provided the requested information to the WHO and served as the basis for one recommendation on treatments for arthralgia due to PCC in the current Guidelines for clinical practice. These results should be interpreted as a first step of indirect evidence able to generate helpful hypotheses for future research.
MeSH term(s)	Humans ; Arthralgia ; COVID-19 ; Systematic Reviews as Topic
Language	English
Publishing date	2022-12-06
Publishing country	Italy
Document type	Journal Article ; Review
ZDB-ID	2426908-6
ISSN	1973-9095 ; 1973-9087
ISSN (online)	1973-9095
ISSN	1973-9087
DOI	10.23736/S1973-9087.22.07803-0
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Article ; Online: Fatigue, post-exertional malaise and orthostatic intolerance: a map of Cochrane evidence relevant to rehabilitation for people with post COVID-19 condition.

Arienti, Chiara / Cordani, Claudio / Lazzarini, Stefano G / Del Furia, Matteo J / Negrini, Stefano / Kiekens, Carlotte

European journal of physical and rehabilitation medicine

2022 Volume 58, Issue 6, Page(s) 857–863

Abstract	Introduction: Rehabilitation focuses on impairments, activity limitations and participation restrictions being informed by the underlying health condition. In the current absence of direct "evidence on" rehabilitation interventions for people with post-COVID-19 condition (PCC), we can search and synthesize the indirect "evidence relevant to" coming from interventions effective for the symptoms of PCC in other health conditions. The World Health Organization (WHO) required this information to inform expert teams and provide specific recommendations in their Guidelines. With this overview of reviews with mapping, we aimed to synthesize in a map the Cochrane evidence relevant to rehabilitation for fatigue, post-exertional malaise and orthostatic intolerance due to PCC. Evidence acquisition: We searched the last five years' Cochrane Systematic Review (CSRs) using the terms "fatigue," "orthostatic intolerance," "rehabilitation" and their synonyms in the Cochrane Library. We extracted and summarized the available evidence using a map. We grouped the included CSRs for health conditions and interventions, indicating the effect and the quality of evidence. Evidence synthesis: Out of 1397 CSRs published between 2016 and 2021, we included 32 for fatigue and 4 for exercise intolerance. They provided data from 13 health conditions, with cancer (11 studies), chronic obstructive pulmonary disease (7 studies), fibromyalgia (4 studies), and cystic fibrosis (3 studies) being the most studied. Effective interventions for fatigue included exercise training and physical activities, telerehabilitation and multicomponent and educational interventions. Effective interventions for exercise intolerance included combined aerobic/anaerobic training and integrated disease rehabilitation management. The overall quality of evidence was low to very low and moderate in very few cases. We did not identify CSRs that specifically addressed post-exertional malaise or orthostatic intolerance. Conclusions: These results are the first step of indirect evidence able to generate helpful hypotheses for clinical practice and future research. They served as the basis for the three recommendations on treatments for these PCC symptoms published in the current WHO Guidelines for clinical practice.
MeSH term(s)	Humans ; COVID-19 ; Exercise ; Fatigue ; Fibromyalgia/therapy ; Orthostatic Intolerance ; Quality of Life ; Systematic Reviews as Topic
Language	English
Publishing date	2022-12-06
Publishing country	Italy
Document type	Journal Article ; Review
ZDB-ID	2426908-6
ISSN	1973-9095 ; 1973-9087
ISSN (online)	1973-9095
ISSN	1973-9087
DOI	10.23736/S1973-9087.22.07802-9
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Rehabilitation and COVID-19: update of the rapid living systematic review by Cochrane Rehabilitation Field as of February 28th, 2022.

de Sire, Alessandro / Andrenelli, Elisa / Negrini, Francesco / Lazzarini, Stefano G / Cordani, Claudio / Ceravolo, Maria G

European journal of physical and rehabilitation medicine

2022 Volume 58, Issue 3, Page(s) 498–501

MeSH term(s)	COVID-19/epidemiology ; COVID-19/rehabilitation ; Humans ; Systematic Reviews as Topic
Language	English
Publishing date	2022-05-25
Publishing country	Italy
Document type	Journal Article
ZDB-ID	2426908-6
ISSN	1973-9095 ; 1973-9087
ISSN (online)	1973-9095
ISSN	1973-9087
DOI	10.23736/S1973-9087.22.07593-1
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Article ; Online: Rehabilitation and COVID-19: update of the rapid living systematic review by Cochrane Rehabilitation Field as of December 31st, 2021.

Negrini, Francesco / de Sire, Alessandro / Andrenelli, Elisa / Lazzarini, Stefano G / Patrini, Michele / Ceravolo, Maria G

European journal of physical and rehabilitation medicine

2022 Volume 58, Issue 2, Page(s) 328–331

MeSH term(s)	COVID-19/epidemiology ; Humans ; SARS-CoV-2
Language	English
Publishing date	2022-03-04
Publishing country	Italy
Document type	Journal Article ; Systematic Review
ZDB-ID	2426908-6
ISSN	1973-9095 ; 1973-9087
ISSN (online)	1973-9095
ISSN	1973-9087
DOI	10.23736/S1973-9087.22.07497-4
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Article ; Online: Introduction to target trial emulation in rehabilitation: a systematic approach to emulate a randomized controlled trial using observational data.

Côté, Pierre / Negrini, Stefano / Donzelli, Sabrina / Kiekens, Carlotte / Arienti, Chiara / Ceravolo, Maria G / Gross, Douglas P / Battel, Irene / Ferriero, Giorgio / Lazzarini, Stefano G / Dan, Bernard / Shearer, Heather M / Wong, Jessica J

European journal of physical and rehabilitation medicine

2024 Volume 60, Issue 1, Page(s) 145–153

Abstract: Rehabilitation providers and policymakers need valid evidence to make informed decisions about the healthcare needs of the population. Whenever possible, these decisions should be informed by randomized controlled trials (RCTs). However, there are ... ...

Abstract	Rehabilitation providers and policymakers need valid evidence to make informed decisions about the healthcare needs of the population. Whenever possible, these decisions should be informed by randomized controlled trials (RCTs). However, there are circumstances when evidence needs to be generated rapidly, or when RCTs are not ethical or feasible. These situations apply to studying the effects of complex interventions, including rehabilitation as defined by Cochrane Rehabilitation. Therefore, we explore using the target trial emulation framework by Hernán and colleagues to obtain valid estimates of the causal effects of rehabilitation when RCTs cannot be conducted. Target trial emulation is a framework guiding the design and analysis of non-randomized comparative effectiveness studies using observational data, by emulating a hypothetical RCT. In the context of rehabilitation, we outline steps for applying the target trial emulation framework using real world data, highlighting methodological considerations, limitations, potential mitigating strategies, and causal inference and counterfactual theory as foundational principles to estimating causal effects. Overall, we aim to strengthen methodological approaches used to estimate causal effects of rehabilitation when RCTs cannot be conducted.
MeSH term(s)	Humans ; Randomized Controlled Trials as Topic ; Rehabilitation ; Comparative Effectiveness Research
Language	English
Publishing date	2024-02-27
Publishing country	Italy
Document type	Journal Article
ZDB-ID	2426908-6
ISSN	1973-9095 ; 1973-9087
ISSN (online)	1973-9095
ISSN	1973-9087
DOI	10.23736/S1973-9087.24.08435-1
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