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  1. Article: A Simple Intraoperative Technique for Restoring Rotational and Length Alignment After Distal Femur Resection and Endoprosthesis Reconstruction: A Technical Note.

    Samargandi, Ramy / Le Nail, Louis-Romée

    Arthroplasty today

    2024  Volume 25, Page(s) 101284

    Abstract: Restoring femoral rotation alignment and limb length after distal femur resection and endoprosthetic reconstruction is crucial to avoid poor outcomes. This technical note presents a simple and reliable intraoperative technique for restoring femoral ... ...

    Abstract Restoring femoral rotation alignment and limb length after distal femur resection and endoprosthetic reconstruction is crucial to avoid poor outcomes. This technical note presents a simple and reliable intraoperative technique for restoring femoral rotation and length during distal femur resection and endoprosthetic reconstruction without the need for extensive preoperative planning or complex perioperative modalities. The method utilizes an external fixator frame as a guiding device to assess and restore the native alignment. This approach provides a practical alternative to relying solely on the position of the linea aspera, which has been shown to be an unreliable landmark for rotational alignment. Implementing this technique can contribute to improved functional outcomes in patients undergoing distal femur endoprosthetic reconstruction.
    Language English
    Publishing date 2024-01-11
    Publishing country United States
    Document type Journal Article
    ISSN 2352-3441
    ISSN 2352-3441
    DOI 10.1016/j.artd.2023.101284
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Cobalt-chromium toxicity following revision of total hip replacement.

    Samargandi, Ramy / Le Nail, Louis-Romée / Hetaimish, Bandar / Saad, Maxime

    Saudi medical journal

    2024  Volume 45, Issue 2, Page(s) 194–198

    Abstract: Systemic cobalt-chromium (Co-Cr) toxicity following a total hip replacement is a rare complication that may sometimes lead to fatal consequences. We report a case of a 64-year-old woman, who presented with Co-Cr toxicity after revision of fractured ... ...

    Abstract Systemic cobalt-chromium (Co-Cr) toxicity following a total hip replacement is a rare complication that may sometimes lead to fatal consequences. We report a case of a 64-year-old woman, who presented with Co-Cr toxicity after revision of fractured ceramic components with metal-on-polyethylene. Systemic toxicity occurred a year after surgery and was expressed brutally with mostly central neurological symptoms. Revision surgery allowed rapid regression of all symptoms. Prosthetic revision with a metal bearing surface after a history of fracture of the ceramic bearing component should be avoided. Orthopedic surgeons and the different medical actors should be aware of this rare but serious complication to allow earlier management. Above all, multidisciplinary management is primordial to allow correct diagnosis and appropriate treatment.
    MeSH term(s) Female ; Humans ; Middle Aged ; Arthroplasty, Replacement, Hip/adverse effects ; Chromium/toxicity ; Hip Prosthesis/adverse effects ; Cobalt/toxicity ; Prosthesis Failure ; Reoperation ; Fractures, Bone ; Prosthesis Design
    Chemical Substances Chromium (0R0008Q3JB) ; Cobalt (3G0H8C9362)
    Language English
    Publishing date 2024-02-02
    Publishing country Saudi Arabia
    Document type Case Reports ; Journal Article
    ZDB-ID 392302-2
    ISSN 1658-3175 ; 0379-5284
    ISSN (online) 1658-3175
    ISSN 0379-5284
    DOI 10.15537/smj.2024.45.2.20230334
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  3. Article: Teaching Potential of Multidisciplinary Tumor Board Meetings for Orthopedic Residents: Insights From a French Sarcoma Reference Center.

    Le Nail, Louis-Romée / Samargandi, Ramy

    Cureus

    2023  Volume 15, Issue 5, Page(s) e39783

    Abstract: Multidisciplinary tumor board meetings (MTBMs) have been established in oncology to improve patient care. While their benefits for patients have been well-documented, there are no previous studies on the teaching opportunities they provide for residents ... ...

    Abstract Multidisciplinary tumor board meetings (MTBMs) have been established in oncology to improve patient care. While their benefits for patients have been well-documented, there are no previous studies on the teaching opportunities they provide for residents and medical students. This study aimed to examine the teaching provided to residents during MTBM and identify areas for improvement. The study hypothesized that although the primary objective of MTBM is not teaching, they could still contribute to residents' learning. The study focused on the tumors board meeting for bone metastasis and musculoskeletal tumors/sarcoma in a French reference center for musculoskeletal oncology. The composition of the MTBM included specialists from various disciplines, and it convened on a weekly basis to discuss cases. The orthopedic oncology residents (OORs) actively participated in the MTBM as part of their training. A questionnaire was distributed to OORs who had served between 2014 and 2021, and their responses were analyzed. The results showed that the OOR perceived MTBM as interesting, beneficial for their training, and challenging. While opinions were divided on whether MTBM was a suitable place for education, the majority believed it improved their knowledge of different specialties and provided valuable elements applicable to daily practice. They also felt it facilitated future access to MTBs if needed. OORs recommended the rotation as an orthopedic oncology resident to younger residents. Recommendations for improvement included incorporating more dedicated teaching time, active involvement of residents in the learning process, availability of learning materials, and post-MTBM debriefing sessions. The study highlighted the importance of case presentations, public speaking skills, interdisciplinary collaboration, and clinical reasoning observed during MTBM. In conclusion, while not primarily designed for teaching, MTBM offers valuable learning opportunities for residents. Enhancing the teaching experience through dedicated debriefing sessions, resident involvement, and improved support can further optimize their educational impact. Future evaluations are needed to assess the effectiveness of these improvements. This study provides insights into the teaching potential within MTBM and can guide educational initiatives in the field of oncology.
    Language English
    Publishing date 2023-05-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.39783
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: A Simple Technique to Prevent Screw Stripping During Hardware Removal Using Bone Wax.

    Samargandi, Ramy / Le Nail, Louis-Romée

    Cureus

    2023  Volume 15, Issue 5, Page(s) e39683

    Abstract: Hardware removal is a common procedure in orthopedics, but it can be challenging and time-consuming. Difficulties in screw removal may arise due to bone growth or cement covering the screw heads, leading to screw damage, and increased surgical time. In ... ...

    Abstract Hardware removal is a common procedure in orthopedics, but it can be challenging and time-consuming. Difficulties in screw removal may arise due to bone growth or cement covering the screw heads, leading to screw damage, and increased surgical time. In this article, we describe a simple and inexpensive technique utilizing bone wax to protect screw heads from bone growth or cement, facilitating future implant removal. The application of bone wax over screw heads acts as a barrier, preventing bone growth or cement from engaging with the screw heads.
    Language English
    Publishing date 2023-05-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.39683
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Angioleiomyoma: An Update with a 142-Case Series.

    Bernard, Mathilde / Le Nail, Louis-Romée / de Pinieux, Gonzague / Samargandi, Ramy

    Life (Basel, Switzerland)

    2024  Volume 14, Issue 3

    Abstract: Angioleiomyomas are uncommon, noncancerous, smooth muscle tumors that primarily arise from blood vessels. Previous studies have yielded limited data due to the lack of interdisciplinary approaches or restricted patient pools. This study aims to provide a ...

    Abstract Angioleiomyomas are uncommon, noncancerous, smooth muscle tumors that primarily arise from blood vessels. Previous studies have yielded limited data due to the lack of interdisciplinary approaches or restricted patient pools. This study aims to provide a comprehensive analysis of angioleiomyomas, including the demographic, clinical, radiological, and histopathological features, with a large number of patients. Conducted as a retrospective investigation at a single center from January 2005 to June 2023, this study involved 142 patients. Relevant information was extracted from electronic medical records, covering clinical, radiological, histological, and demographic details. Angioleiomyomas mostly occurred at age 59 (1-87), predominately affect females (53%) and commonly arise in subcutaneous tissue (85%) and the lower limbs (76%). MRI findings revealed characteristic signals, with a high prevalence of the solid histologic type (65%), often displaying a reticular sign. Smooth muscle Actin was universally present (n = 95/95), while Desmin and Caldesmon showed positive expression in 83% (n = 71/85) and 98% (n = 92/94) of cases, respectively. This study presents an updated and comprehensive analysis of angioleiomyomas. Typically appearing as well-defined nodules in the extremities, these tumors can be effectively diagnosed using MRI, though histopathological analysis is generally essential for confirmation. Treatment primarily involves straightforward excision, with notable low complication and recurrence rates.
    Language English
    Publishing date 2024-03-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662250-6
    ISSN 2075-1729
    ISSN 2075-1729
    DOI 10.3390/life14030338
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Cauda Equina Syndrome Secondary to Incidental Hemorrhagic Ependymoma Following Spinal Anesthesia: A Case Report and Comprehensive Review.

    Samargandi, Ramy / Alesawi, Abdulrahman / Le Nail, Louis-Romée / Abualross, Osamah

    Cureus

    2023  Volume 15, Issue 6, Page(s) e40490

    Abstract: Spinal ependymomas are rare primary central nervous system tumors that often exhibit vague symptoms before being identified. In extremely rare situations, it can be identified after a neurological decline following a history of spinal anesthesia, ... ...

    Abstract Spinal ependymomas are rare primary central nervous system tumors that often exhibit vague symptoms before being identified. In extremely rare situations, it can be identified after a neurological decline following a history of spinal anesthesia, indicating intraspinal hemorrhages from an incidental lumbar ependymoma that was not previously diagnosed. Spinal anesthesia is widely utilized in numerous orthopedic surgical procedures, as it is a well-tolerated invasive procedure with a low risk of complications. The patient in this case study underwent elective orthopedic surgery under general anesthesia following two unsuccessful trials with spinal anesthesia. Subsequently, the patient developed paraplegia as a result of an incidental hemorrhagic spinal ependymoma. The patient had an L3 laminectomy for decompression of the dural sheath, and an ependymoma was confirmed based on the histopathological assessment. This case report aims to raise awareness regarding the potential complication of spinal anesthesia arising from incidental tumors of the spinal cord, thereby emphasizing the imperative of early recognition and management in order to mitigate adverse outcomes.
    Language English
    Publishing date 2023-06-15
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.40490
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  7. Article ; Online: Impact of preoperative varus on ankle replacement survival.

    Boble, Maxime / Le Nail, Louis-Romée / Brilhault, Jean

    Orthopaedics & traumatology, surgery & research : OTSR

    2022  Volume 108, Issue 7, Page(s) 103390

    Abstract: Introduction: The severity of a foot or ankle deformity is a major prognostic factor for the success of ankle replacement. Varus deformity is at once the most arthrogenic and the most frequent.: Hypothesis: The severity of preoperative varus is a ... ...

    Abstract Introduction: The severity of a foot or ankle deformity is a major prognostic factor for the success of ankle replacement. Varus deformity is at once the most arthrogenic and the most frequent.
    Hypothesis: The severity of preoperative varus is a negative factor for ankle replacement survival.
    Material and method: A retrospective study compared results in a continuous series of 57 Salto-Talaris® ankle replacements according to preoperative varus: 31 moderate (5-15̊) and 26 severe (> 15̊). Radiological and clinical assessment at a minimum 1 year focused on complications, revision and implant exchange and on AOFAS score, range of motion and tibiotalar angle at last follow-up.
    Results: At a mean 2.4 years' follow-up, implant survival in the moderate and severe varus groups was respectively 83% and 92%. Postoperative AOFA score and range of motion improved significantly in both groups, without significant difference. Analysis of cumulative survival showed no significant intergroup difference.
    Discussion: Severity of preoperative varus did not impact implant survival. Only postoperative alignment and stability emerged as survival factors. These results were related to the quality of associated procedures aiming to reduce deformity and to achieve ligament balance.
    Level of evidence: IV, retrospective comparative study.
    MeSH term(s) Humans ; Retrospective Studies ; Ankle ; Treatment Outcome ; Arthroplasty, Replacement, Ankle ; Ankle Joint/diagnostic imaging ; Ankle Joint/surgery
    Language English
    Publishing date 2022-08-06
    Publishing country France
    Document type Journal Article
    ISSN 1877-0568
    ISSN (online) 1877-0568
    DOI 10.1016/j.otsr.2022.103390
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  8. Article ; Online: Recent progress in orthopedic oncology and locomotor system tumor surgery.

    Crenn, Vincent / Le Nail, Louis-Romée / Bonnevialle, Paul

    Orthopaedics & traumatology, surgery & research : OTSR

    2022  Volume 108, Issue 4, Page(s) 103310

    MeSH term(s) Humans ; Musculoskeletal System ; Neoplasms ; Orthopedic Procedures ; Orthopedics
    Language English
    Publishing date 2022-05-01
    Publishing country France
    Document type Editorial
    ISSN 1877-0568
    ISSN (online) 1877-0568
    DOI 10.1016/j.otsr.2022.103310
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  9. Article ; Online: Fully hydroxyapatite-coated distal locking cementless femoral modular implant for revision total hip arthroplasty: A retrospective study of 94 Renaissance™ stems at a minimum 10 years' follow-up.

    Slomka, Fabien / Druon, Jérôme / Rosset, Philippe / Le Nail, Louis-Romée

    Orthopaedics & traumatology, surgery & research : OTSR

    2022  Volume 108, Issue 6, Page(s) 103233

    Abstract: Introduction: Modular locking revision total hip arthroplasty femoral implants have been little assessed over the long term. We therefore conducted a retrospective assessment of the Renaissance™ fully hydroxyapatite-coated distal locking cementless ... ...

    Abstract Introduction: Modular locking revision total hip arthroplasty femoral implants have been little assessed over the long term. We therefore conducted a retrospective assessment of the Renaissance™ fully hydroxyapatite-coated distal locking cementless femoral modular revision implant at a minimum 10 years' follow-up, analyzing: 1) survivorship, 2) complications, 3) radiologic and functional results, and 4) prevalence of thigh pain.
    Hypothesis: This implant shows more than 90% 10-year survival.
    Material and method: Between December 2002 and December 2008, 213 implant exchanges were performed in 206 patients, including 97 Renaissance™ stems in 93 patients. Three patients were excluded for missing data. Survival was analyzed for 94 stems in 90 patients at a mean 11.2±3 years' follow-up; radiographic and clinical assessment was performed for 48 stems in 45 patients. The survival criterion was implant fracture and/or femoral stem removal.
    Results: Survival was 93.5% at 10 years (95% CI: 86-97) and 91.3% at 15 years (95% CI: 82.9-96). Eight stems (8.5%) were exchanged or removed by last follow-up: 5 for infection (5.3%) and 3 for implant breakage (3.2%). The complications rate was 18.1% (N=17, including the 8 stem revisions): 3 stem exchanges for breakage (3.2%), 9 stem infections (9.6%), 3 dislocations (3.2%), and 2 traumatic greater trochanter fractures (2.1%). For the 45 patients with long-term clinical assessment, the mean Postel Merle d'Aubigné and Harris Hip scores were respectively 15±3 and 80 ±19 at last follow-up. Metaphysis reconstruction was satisfactory in 36/48 cases (75.0%). Seven of the 48 stems (14.6%) assessed at longest follow-up, in 45 patients, were causing thigh pain, unrelated to stress-shielding, distal locking screws or metaphyseal filling index.
    Discussion: The Renaissance™ fully hydroxyapatite-coated modular locking stem with curved nail showed 90% 10-year survival, with satisfactory functional results and little thigh pain.
    Level of evidence: IV; case study without control group.
    MeSH term(s) Arthroplasty, Replacement, Hip/methods ; Durapatite ; Femur/surgery ; Follow-Up Studies ; Hip Prosthesis ; Humans ; Pain/surgery ; Prosthesis Design ; Prosthesis Failure ; Reoperation ; Retrospective Studies ; Treatment Outcome
    Chemical Substances Durapatite (91D9GV0Z28)
    Language English
    Publishing date 2022-02-03
    Publishing country France
    Document type Journal Article
    ISSN 1877-0568
    ISSN (online) 1877-0568
    DOI 10.1016/j.otsr.2022.103233
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  10. Article: Intraosseous Hibernoma: A Rare Entity in Orthopedics With Peculiar Radiological Features.

    Samargandi, Ramy / Le Nail, Louis-Romée / de Pinieux, Gonzague / Tallegas, Matthias / Miquelestorena-Standley, Elodie

    Cureus

    2023  Volume 15, Issue 6, Page(s) e39883

    Abstract: Intraosseous hibernoma is a rare benign bone tumor derived from brown fat. It is typically found in the axial skeleton and is more commonly observed in women. It can manifest as a painful lesion or may be incidentally discovered. Intraosseous hibernoma ... ...

    Abstract Intraosseous hibernoma is a rare benign bone tumor derived from brown fat. It is typically found in the axial skeleton and is more commonly observed in women. It can manifest as a painful lesion or may be incidentally discovered. Intraosseous hibernoma often presents as a sclerotic lesion, although it can also manifest as a lytic lesion. Due to its varied radiographic appearance, it should be considered in the differential diagnosis of bone lesions as it can mimic metastatic lesions as well as other sclerotic and lytic bone lesions. Therefore, obtaining a biopsy of the lesion is crucial for an accurate diagnosis. In this report, we present the clinical, radiological, and histopathological findings of two cases of intraosseous hibernoma and provide a concise overview based on a review of the literature.
    Language English
    Publishing date 2023-06-02
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.39883
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