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  1. Article ; Online: Reproducibility of Oxford Scoring in IgA Nephropathy: Is the Noise Due to an Educational Gap?

    Herlitz, Leal C

    Kidney360

    2023  Volume 4, Issue 8, Page(s) 1017–1018

    MeSH term(s) Humans ; Glomerulonephritis, IGA/diagnosis ; Reproducibility of Results ; Educational Status
    Language English
    Publishing date 2023-08-29
    Publishing country United States
    Document type Editorial ; Comment
    ISSN 2641-7650
    ISSN (online) 2641-7650
    DOI 10.34067/KID.0000000000000234
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Wild and trapped: a history of Colombian zoos and its revelations of animal fortunes and State entanglements, 1930s-1990s.

    Leal, Claudia

    Historia, ciencias, saude--Manguinhos

    2022  Volume 28, Issue suppl 1, Page(s) 81–101

    Abstract: This article presents the first history of Colombian zoos and one of the few contributions to the history of these institutions in Latin America. It proposes that in this region's zoos native animals tended to predominate, signaling the increasing ... ...

    Abstract This article presents the first history of Colombian zoos and one of the few contributions to the history of these institutions in Latin America. It proposes that in this region's zoos native animals tended to predominate, signaling the increasing transformation of forests and other native ecosystems into croplands and pasturelands, as well as the growing distance between people and natural environments. Colombian zoos additionally underscore the limitations of the State in its period of most rapid expansion. They reveal how private interests overshadowed the State by providing public amenities, but also how they offered unconventional solutions to certain hurdles of State formation.
    MeSH term(s) Animals ; Animals, Zoo ; Colombia ; Ecosystem ; Forests ; Humans
    Language Portuguese
    Publishing date 2022-02-05
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 2053148-5
    ISSN 1678-4758 ; 0104-5970
    ISSN (online) 1678-4758
    ISSN 0104-5970
    DOI 10.1590/S0104-59702021000500008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Microfluidic synthesis of multilayered lipid-polymer hybrid nanoparticles for the formulation of low solubility drugs.

    Kambar, Nurila / Leal, Cecília

    Soft matter

    2023  Volume 19, Issue 8, Page(s) 1596–1605

    Abstract: Hybrid phospholipid/block copolymer membranes where polymers and lipids are molecularly mixed or phase-separated into polymer-rich and lipid-rich domains are promising drug delivery materials. Harnessing the chemical diversity of polymers and the ... ...

    Abstract Hybrid phospholipid/block copolymer membranes where polymers and lipids are molecularly mixed or phase-separated into polymer-rich and lipid-rich domains are promising drug delivery materials. Harnessing the chemical diversity of polymers and the biocompatability of lipids is a compelling approach to design the next generation of drug carriers. Here, we report on the development of a microfluidics-based strategy analogous to produce lipid nanoparticles (LNPs) for the nanomanufacturing of multilayered hybrid nanoparticles (HNPs). Using X-ray scattering, Cryo-electron, and polarized microscopy we show that phosphatidylcholine (PC) and PBD-
    MeSH term(s) Polymers/chemistry ; Solubility ; Microfluidics ; Nanoparticles/chemistry ; Liposomes ; Lipids/chemistry
    Chemical Substances Polymers ; Lipid Nanoparticles ; Liposomes ; Lipids
    Language English
    Publishing date 2023-02-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 2191476-X
    ISSN 1744-6848 ; 1744-683X
    ISSN (online) 1744-6848
    ISSN 1744-683X
    DOI 10.1039/d2sm01443b
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  4. Article ; Online: A different kind of polyp.

    Leal, C / Silva, M / Cotrim, I

    Revista de gastroenterologia de Mexico (English)

    2022  Volume 87, Issue 3, Page(s) 380–381

    MeSH term(s) Colonic Polyps/diagnostic imaging ; Colonic Polyps/surgery ; Humans
    Language English
    Publishing date 2022-06-28
    Publishing country Mexico
    Document type Case Reports
    ZDB-ID 2828765-4
    ISSN 2255-534X ; 2255-534X
    ISSN (online) 2255-534X
    ISSN 2255-534X
    DOI 10.1016/j.rgmxen.2022.06.002
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  5. Article: An elderly patient's pancreatobiliary puzzle: unraveling diagnosis and treatment challenges.

    Gonçalves, André / Leal, Carina / Cotrim, Isabel / Vasconcelos, Helena

    Revista espanola de enfermedades digestivas

    2024  

    Abstract: Pancreatobiliary fistulas associated withntraductal Papillary Mucinous Neoplasm (IPMN) are rare and present therapeutic challenges. The authors describe the clinical course of an 81-year-old woman presenting with acute cholangitis, ultimately diagnosed ... ...

    Abstract Pancreatobiliary fistulas associated withntraductal Papillary Mucinous Neoplasm (IPMN) are rare and present therapeutic challenges. The authors describe the clinical course of an 81-year-old woman presenting with acute cholangitis, ultimately diagnosed with IPMN involving secondary ducts with focal high-grade dysplasia. Initial manifestations included elevated inflammatory markers, cholestasis, and imaging findings of a pancreatic lesion. Endoscopic retrograde cholangiopancreatography revealed dilation of both intrahepatic and extrahepatic bile ducts, along a cystic cluster originating from the pancreas, fistulizing into the common bile duct. Despite initial endoscopic interventions, recurrent cholestasis persisted. Subsequent multidisciplinary evaluation led to a cephalic duodenopancreatectomy. This case underscores the rarity of pancreatobiliary fistulas associated with IPMNs and the subsequent therapeutic challenges. The absence of standardized treatment algorithms for such intricate cases emphasizes the importance of individualized approaches. The fluoroscopy image displaying a cystic cluster originating from the pancreas and showing fistulization into the common bile duct is a rare image presented in our report, unique to this case.
    Language English
    Publishing date 2024-01-11
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 1070381-0
    ISSN 1130-0108 ; 0212-7512
    ISSN 1130-0108 ; 0212-7512
    DOI 10.17235/reed.2024.10125/2023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 199: Show issues Location:
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  6. Article: A Rare Case of Pulmonary Artery Sarcoma.

    Brazão Carvalho, Vera / Roque Almeida, João / Leal, Cecília

    Portuguese journal of cardiac thoracic and vascular surgery

    2024  Volume 30, Issue 4, Page(s) 71–73

    Abstract: Pulmonary artery sarcoma (PAS) is a rare and aggressive mesenchymal tumor with an overall poor prognosis1-5. Due to similar clinical and radiologic findings, PAS is often misdiagnosed as a pulmonary embolism (PE) frequently leading to prolonged ... ...

    Abstract Pulmonary artery sarcoma (PAS) is a rare and aggressive mesenchymal tumor with an overall poor prognosis1-5. Due to similar clinical and radiologic findings, PAS is often misdiagnosed as a pulmonary embolism (PE) frequently leading to prolonged anticoagulation therapy, which delays the correct diagnosis 1-3. By presenting this clinical case our objective is to emphasize characteristic CT findings that favour a neoplastic origin of a pulmonary intravascular filling defect. PET-CT and MRI have also an important potential role in its diagnosis and therapeutical management.
    MeSH term(s) Humans ; Pulmonary Artery/diagnostic imaging ; Positron Emission Tomography Computed Tomography ; Vascular Neoplasms/diagnosis ; Pulmonary Embolism/diagnosis ; Sarcoma/diagnosis ; Neoplasms, Vascular Tissue/pathology ; Lung Neoplasms/diagnosis
    Language English
    Publishing date 2024-02-09
    Publishing country Portugal
    Document type Case Reports ; Journal Article
    ISSN 2184-9927
    ISSN 2184-9927
    DOI 10.48729/pjctvs.369
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: PAM50 and Pathologic Tumor Size.

    Leal, Conceição

    Archives of pathology & laboratory medicine

    2018  Volume 142, Issue 12, Page(s) 1455

    MeSH term(s) Breast Neoplasms/classification ; Breast Neoplasms/diagnosis ; Breast Neoplasms/genetics ; Breast Neoplasms/pathology ; Female ; Humans ; Lymphatic Metastasis/pathology ; Neoplasm Recurrence, Local ; Practice Guidelines as Topic ; Prognosis ; RNA, Messenger/analysis ; Reagent Kits, Diagnostic
    Chemical Substances RNA, Messenger ; Reagent Kits, Diagnostic
    Language English
    Publishing date 2018-11-29
    Publishing country United States
    Document type Letter
    ZDB-ID 194119-7
    ISSN 1543-2165 ; 0363-0153 ; 0096-8528 ; 0003-9985
    ISSN (online) 1543-2165
    ISSN 0363-0153 ; 0096-8528 ; 0003-9985
    DOI 10.5858/arpa.2018-0300-LE
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ud II Zs.36: Show issues Location:
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  8. Article: Pemphigus vulgaris presenting as esophageal ulceration. Report of an underdiagnosed manifestation.

    Leal, C / Silva, M / Barbeiro, S / Vasconcelos, H

    Acta gastro-enterologica Belgica

    2021  Volume 84, Issue 2, Page(s) 365–366

    Abstract: Pemphigus vulgaris (PV) is a rare autoimmune blistering disorder of the skin and mucous membranes. The true prevalence of esophageal involvement is unknown; esophageal symptoms almost always occur in the context of oral mucosa involvement. We report the ... ...

    Abstract Pemphigus vulgaris (PV) is a rare autoimmune blistering disorder of the skin and mucous membranes. The true prevalence of esophageal involvement is unknown; esophageal symptoms almost always occur in the context of oral mucosa involvement. We report the case of a 66-year-old man with cutaneous blisters and esophageal symptoms that did not respond to acid suppression therapy. Esophagogastroduodenoscopy showed esophageal ulcers and mucosal desquamation. Biopsies were consistent with the diagnosis of PV. The patient was started on immunosuppressive therapy, achieving remission. This represents a rare case of esophageal involvement of PV without mucosal involvement and draws attention to a rare cause of dysphagia, which can be fatal if left untreated.
    MeSH term(s) Aged ; Deglutition Disorders ; Esophageal Diseases ; Humans ; Male ; Pemphigus ; Skin
    Language English
    Publishing date 2021-07-03
    Publishing country Belgium
    Document type Case Reports
    ZDB-ID 127060-6
    ISSN 1784-3227 ; 0001-5644
    ISSN 1784-3227 ; 0001-5644
    DOI 10.51821/84.2.365
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  9. Article: Musculoskeletal Injury in Australian Professional Musical Theatre Shows: A 5-Year Retrospective Observation Study of 2,249 Medical Attention Injuries.

    Ganderton, Charlotte / Strauch, Annie / Etty-Leal, Catherine / Pranata, Adrian

    Medical problems of performing artists

    2024  Volume 39, Issue 1, Page(s) 1–7

    Abstract: Objective: To investigate the frequency and trends of musculoskeletal medical attention injuries occurring in Australian professional musical theatre performers over two consecutive Australian city tours.: Methods: Medical attention performance- ... ...

    Abstract Objective: To investigate the frequency and trends of musculoskeletal medical attention injuries occurring in Australian professional musical theatre performers over two consecutive Australian city tours.
    Methods: Medical attention performance-related injuries were prospectively reported from 269 professional Australian music theatre performers across nine professional music theatre productions from 2015 to 2020. Medical attention injuries were defined as a presentation to physiotherapy for assessment or treatment of a body region that may or may not have resulted in time lost on stage.
    Results: 844 injuries were reported in City 1 and 776 injuries were reported in the City 2. The proportion of performers reporting injuries in City 1 ranged from 39.5% to 96.4% and in City 2, from 15.4% to 92.9%. Cervical spine injuries (ncity1 = 194, ncity2 = 187) were the most prevalent musculoskeletal presentation to physiotherapy followed by lumbar spine (ncity1 = 124, ncity2 = 117) and thoracic spine (ncity1 = 124, ncity2 = 90). There were more acute injuries reported in City 1 than City 2 (adj residuals = -4.09, p < 0.001) and more persistent injuries in City 2 (adj residuals = 4.09, p < 0.001).
    Conclusion: Almost half of all injuries requiring medical attention in Australian professional music theatre performers were related to the cervical, thoracic and lumbar spine, with an increasing trend of cervical spine injury frequency across show durations. The study suggests a need for targeted injury prevention strategies in this population.
    MeSH term(s) Humans ; Australia/epidemiology ; Lumbar Vertebrae ; Musculoskeletal Diseases/epidemiology ; Music ; Retrospective Studies ; Spinal Injuries
    Language English
    Publishing date 2024-02-28
    Publishing country United States
    Document type Observational Study ; Journal Article
    ZDB-ID 639194-1
    ISSN 0885-1158
    ISSN 0885-1158
    DOI 10.21091/mppa.2024.1001
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  10. Article ; Conference proceedings: Secondary Prophylaxis in Variceal Hemorrhage: In Search of the Ideal Endoscopic Timing

    Gonçalves, A. / Simas, D. / Gomes, P. / Barbeiro, S. / Leal, C. / Martins, C. / Vasconcelos, H.

    Endoscopy

    2024  Volume 56, Issue S 02

    Event/congress ESGE Days 2024, Berlin, Germany, 2024-04-25
    Language English
    Publishing date 2024-04-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/s-0044-1783248
    Database Thieme publisher's database

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