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Article ; Online: Pain Fellows Survey: COVID-19 Impact on the Training and Job Market.

Lee, David W / Deer, Timothy

2021 Volume 22, Issue 12, Page(s) 3106–3109

MeSH term(s)	COVID-19 ; Humans ; Pain ; SARS-CoV-2
Language	English
Publishing date	2021-05-24
Publishing country	England
Document type	Journal Article
ZDB-ID	2015903-1
ISSN	1526-4637 ; 1526-2375
ISSN (online)	1526-4637
ISSN	1526-2375
DOI	10.1093/pm/pnab165
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Zs.A 6119: Show issues

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Article ; Online: Sheathless Radial Artery Access: Opening Doors for the "Unreasonable" Radial Operator.

Baker, Nevin C / Lee, David W

Cardiovascular revascularization medicine : including molecular interventions

2020 Volume 22, Page(s) 98–99

MeSH term(s)	Cardiac Catheterization ; Cardiac Catheters ; Humans ; Radial Artery/diagnostic imaging ; Radial Artery/surgery
Language	English
Publishing date	2020-11-20
Publishing country	United States
Document type	Editorial ; Comment
ZDB-ID	2212113-4
ISSN	1878-0938 ; 1553-8389
ISSN (online)	1878-0938
ISSN	1553-8389
DOI	10.1016/j.carrev.2020.10.008
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Zs.A 5562: Show issues

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Article ; Online: Periprocedural Myocardial Infarction in Contemporary Practice.

Lee, David W / Cavender, Matthew A

Interventional cardiology clinics

2019 Volume 8, Issue 2, Page(s) 209–223

Abstract: Periprocedural myocardial infarction (MI) occurs infrequently in the current era of percutaneous coronary interventions (PCI) and is associated with an increased risk of mortality and morbidity. Periprocedural MI can occur due to acute side branch ... ...

Abstract	"Periprocedural myocardial infarction (MI) occurs infrequently in the current era of percutaneous coronary interventions (PCI) and is associated with an increased risk of mortality and morbidity. Periprocedural MI can occur due to acute side branch occlusion, distal embolization, slow flow or no reflow phenomenon, abrupt vessel closure, and nonidentifiable mechanical processes. Therapeutic strategies to reduce the risk of periprocedural MI include dual antiplatelet therapy, intravenous cangrelor in the periprocedural setting, intravenous glycoprotein IIb/IIIa inhibitor in high-risk patients, anticoagulation with unfractionated heparin, low-molecular-weight heparin or bivalirudin, and embolic protection devices during saphenous vein graft interventions."
MeSH term(s)	Coronary Occlusion/complications ; Embolic Protection Devices ; Humans ; Myocardial Infarction/etiology ; Myocardial Infarction/therapy ; Percutaneous Coronary Intervention ; Platelet Aggregation Inhibitors/therapeutic use ; Preoperative Care/methods ; Treatment Outcome
Chemical Substances	Platelet Aggregation Inhibitors
Language	English
Publishing date	2019-01-28
Publishing country	Netherlands
Document type	Journal Article ; Review
ISSN	2211-7466
ISSN (online)	2211-7466
DOI	10.1016/j.iccl.2018.12.001
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Article: Review of Current Evidence for Minimally Invasive Posterior Sacroiliac Joint Fusion.

Lee, David W / Patterson, Denis G / Sayed, Dawood

International journal of spine surgery

2021 Volume 15, Issue 3, Page(s) 514–524

Abstract: The sacroiliac joint (SIJ) is a large, irregularly shaped, serpentine joint structure bordered anteriorly and posteriorly by the sacroiliac ligaments. With increased recognition of the SIJ as a pain source, treatments have been historically nonsurgical ... ...

Abstract	The sacroiliac joint (SIJ) is a large, irregularly shaped, serpentine joint structure bordered anteriorly and posteriorly by the sacroiliac ligaments. With increased recognition of the SIJ as a pain source, treatments have been historically nonsurgical in nature. Common treatments include bracing, medications, activity modification, manual therapy, chiropractic manipulation, physical therapy, and intra-articular SIJ injections. Surgical stabilization and/or fusion of the SIJ may be considered when a patient has persistent moderate to severe pain, functional impairment, and failed conservative management. Surgical stabilization and fusion has traditionally been by way of the transiliac approach. More recent SIJ fusion systems have proposed not only a posterior approach but one that stabilizes the joint space by placing an allograft within the SIJ. Anatomically, a posterior approach is able to avoid neurovascular structures that otherwise are encountered with the transiliac approach and may be performed percutaneously. Preliminary evidence reports consistent pain reduction with minimal complications. This paper is purposed to detail the present evidence of minimally invasive posterior SIJ fusion, as well as highlight the need for further research moving forward.
Language	English
Publishing date	2021-05-07
Publishing country	Netherlands
Document type	Journal Article
ISSN	2211-4599
ISSN	2211-4599
DOI	10.14444/8073
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Article ; Online: Guidelines for Peripheral Vascular Disease: Where Is the Evidence?

Lee, David W / Cavender, Matthew A

Circulation. Cardiovascular interventions

2019 Volume 12, Issue 1, Page(s) e007561

MeSH term(s)	American Heart Association ; Cardiology ; Humans ; Peripheral Vascular Diseases ; Platelet Aggregation Inhibitors ; United States
Chemical Substances	Platelet Aggregation Inhibitors
Language	English
Publishing date	2019-01-14
Publishing country	United States
Document type	Editorial ; Comment
ZDB-ID	2450797-0
ISSN	1941-7632 ; 1941-7640
ISSN (online)	1941-7632
ISSN	1941-7640
DOI	10.1161/CIRCINTERVENTIONS.118.007561
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Zs.A 6746: Show issues

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Article ; Online: Review of Interventional Treatments for Cluneal Neuropathy.

Gill, Benjamin / Cheng, David S / Buchanan, Patrick / Lee, David W

Pain physician

2022 Volume 25, Issue 5, Page(s) 355–363

Abstract: Background: The most common presentation of cluneal neuropathy is ipsilateral low back and gluteal pain. Cluneal neuralgia has been described historically in surgical contexts, with much of the description and treatment related to entrapment and ... ...

Abstract	Background: The most common presentation of cluneal neuropathy is ipsilateral low back and gluteal pain. Cluneal neuralgia has been described historically in surgical contexts, with much of the description and treatment related to entrapment and decompression, respectively. Treatment options for addressing axial low back pain have evolved with advancements in the field of interventional pain medicine, though clinical results remain inconsistent. Recent attention has turned toward peripheral nerve stimulation. Nonsurgical interventions targeting the superior and medial cluneal nerve branches have been performed in cases of low back and buttock pain, but there is no known review of the resulting evidence to support these practices. Objectives: In this manuscript we provide a robust exploration and analysis of the available literature regarding treatment options for cluneal neuropathy. We provide clinical manifestations and recommendations for future study direction. Study design: Narrative review. Methods: This was a systematic, evidence-based narrative, performed after extensive review of the literature to identify all manuscripts associated with interventional treatment of the superior and medial cluneal nerves. Results: Eleven manuscripts fulfilled inclusion criteria. Interventional treatment of the superior and middle cluneal nerves includes blockade with corticosteroid, alcohol neurolysis, peripheral nerve stimulation, radiofrequency neurotomy, and surgical decompression. Limitations: The supportive evidence for interventions in cluneal neuropathy is largely lacking due to small, uncontrolled, observational studies with multiple confounding factors. There is no standardized definition of cluneal neuropathy. Conclusion: Limited studies promote beneficial effects from interventions intended to target cluneal neuropathy. Despite increased emphasis and treatment options for this condition, there is little consensus on the diagnostic criteria, endpoints, and measures of therapeutics, or procedural techniques for blocks, radiofrequency, and neuromodulation. It is imperative to delineate pathology associated with the cluneal nerves and perform rigorous analysis of associated treatment options.
MeSH term(s)	Buttocks/innervation ; Buttocks/surgery ; Decompression, Surgical ; Humans ; Low Back Pain/surgery ; Neuralgia/surgery ; Peripheral Nerves/surgery
Language	English
Publishing date	2022-07-28
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2146393-1
ISSN	2150-1149 ; 1533-3159
ISSN (online)	2150-1149
ISSN	1533-3159
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Zs.A 5930: Show issues

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Article ; Online: Fluoroscopically-Guided Cervical Zygapophyseal Therapeutic Joint Injections May Reduce the Need for Radiofrequency.

Lee, David W / Huston, Christopher

Pain physician

2018 Volume 21, Issue 6, Page(s) E661–E665

Abstract: Background: There is a paucity of literature studying therapeutic intraarticular zygapophyseal (commonly referred to as facet) joint injections in the atraumatic patient population. As a result of this, intraarticular injections have been dismissed as a ...

Abstract	Background: There is a paucity of literature studying therapeutic intraarticular zygapophyseal (commonly referred to as facet) joint injections in the atraumatic patient population. As a result of this, intraarticular injections have been dismissed as a possible treatment for cervical zygapophyseal joint-mediated pain. Radiofrequency neurotomy (RFN) is currently the accepted treatment for facet joint neck pain. Objective: This prospective observational study investigated injection response in an atraumatic population to determine treatment viability and whether injections reduce the need for RFN in neck pain patients. Study design: Observational case series study. Setting: This study took place in the outpatient clinic of a private practice. Methods: The double-block paradigm (DBP) was used to determine if symptoms were zygapophyseal joint-mediated. Lidocaine and bupivacaine diagnostic injections were used. Participants passing the DBP underwent fluoroscopically-guided cervical zygapophyseal joint injections (betamethasone and 1% lidocaine) and 1 year of follow-up. Outcomes were a Verbal Numeric Scale score (VNS) > 2, 50% decrease in VNS, patient-reported improvement, and opioid use at the 1-year follow-up. Results: One hundred and eighteen patients were enrolled; 51 passed the DBP. These 51 patients underwent injections. Forty-four patients (59 joints) were surveyed 1 year later with 7 follow-up losses. Thirty-four of 59 joints showed ≥2-point VNS reductions or ≥ 50% overall symptomatic improvement after 1 year. Twenty-four of 44 ceased narcotics use. Limitations: The limitations of this research included the lack of randomization and blinding, smaller sample size, and reliance on subjective reporting from the participants both immediately after the procedures and at follow-up. As this was a prospective observational study, there is the possibility of unintended bias by both patients as well as the authors. Conclusion: Cervical zygapophyseal joint injections may reduce the need for RFN; additional studies are required. Key words: Neck pain, facet joint, cervical zygapophyseal joint injections, radiofrequency neurotomy.
MeSH term(s)	Adult ; Anti-Inflammatory Agents/administration & dosage ; Arthralgia/drug therapy ; Betamethasone/administration & dosage ; Bupivacaine/administration & dosage ; Female ; Humans ; Injections, Intra-Articular/methods ; Lidocaine/administration & dosage ; Male ; Middle Aged ; Neck Pain/drug therapy ; Pain Management/methods ; Prospective Studies ; Zygapophyseal Joint
Chemical Substances	Anti-Inflammatory Agents ; Betamethasone (9842X06Q6M) ; Lidocaine (98PI200987) ; Bupivacaine (Y8335394RO)
Language	English
Publishing date	2018-11-22
Publishing country	United States
Document type	Journal Article ; Observational Study
ZDB-ID	2146393-1
ISSN	2150-1149 ; 1533-3159
ISSN (online)	2150-1149
ISSN	1533-3159
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Zs.A 5930: Show issues

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Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

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Article ; Online: Sacral Burst Neuromodulation via Caudal Approach as a Treatment for Chronic Coccydynia.

Lee, David W / Lai, Albert

Neuromodulation : journal of the International Neuromodulation Society

2018 Volume 22, Issue 8, Page(s) 992–994

MeSH term(s)	Aged ; Back Pain/diagnostic imaging ; Back Pain/therapy ; Chronic Disease ; Coccyx/diagnostic imaging ; Coccyx/physiology ; Humans ; Implantable Neurostimulators ; Male ; Sacrum/diagnostic imaging ; Sacrum/physiology ; Spinal Cord Stimulation/instrumentation ; Spinal Cord Stimulation/methods ; Transcutaneous Electric Nerve Stimulation/instrumentation ; Transcutaneous Electric Nerve Stimulation/methods ; Treatment Outcome
Language	English
Publishing date	2018-08-17
Publishing country	United States
Document type	Case Reports ; Letter
ZDB-ID	1500372-3
ISSN	1525-1403 ; 1094-7159
ISSN (online)	1525-1403
ISSN	1094-7159
DOI	10.1111/ner.12808
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Zs.A 5912: Show issues

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Article ; Online: Far-Contralateral Oblique (FCO) Sacroiliac Joint Injection: Description of a Novel Technique.

Lee, David W / Buchanan, Patrick / Vodapally, Shashank / James, Christopher / Diep, Jack

Pain research & management

2022 Volume 2022, Page(s) 3312589

Abstract: Sacroiliac (SI) joint arthropathy is the primary pain generator in approximately 15-25% of patients with axial low back pain and traditionally diagnosed with >50% pain reduction following an intra-articular injection localized to the inferior 1/3 of the ... ...

Abstract	Sacroiliac (SI) joint arthropathy is the primary pain generator in approximately 15-25% of patients with axial low back pain and traditionally diagnosed with >50% pain reduction following an intra-articular injection localized to the inferior 1/3 of the SI joint. The conventional technique for accessing the SI joint encompasses a posterior approach with fluoroscopic guidance at 10-20⁰ contralateral oblique angulation, and minor adjustments to this approach have been implemented with varying degrees of success. The authors present a novel technique for SI joint injection, infiltrating the middle third of the joint through an alternative far-contralateral oblique (FCO) approach, angulation between 20-40⁰. This approach theoretically endows easier access to the SI joint and at the very least provides another option for interventionalists in the diagnosis and treatment of sacroiliac joint pain. It can also be utilized to determine if a patient is a candidate for posterior percutaneous SI joint fusion. The authors sought to document this approach to ensure that it was both reproducible and safe, while recognizing the need for future studies.
MeSH term(s)	Arthralgia ; Fluoroscopy ; Humans ; Injections, Intra-Articular/methods ; Low Back Pain/diagnostic imaging ; Low Back Pain/drug therapy ; Sacroiliac Joint/diagnostic imaging
Language	English
Publishing date	2022-08-22
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2041085-2
ISSN	1918-1523 ; 1203-6765
ISSN (online)	1918-1523
ISSN	1203-6765
DOI	10.1155/2022/3312589
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Zs.A 5498: Show issues

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Article ; Online: Safety and Efficacy of Intravenous ExoFlo in the Treatment of Complex Regional Pain Syndrome.

Paicius, Rick / White, Zeyn S / Smith, Cassandra / Lightner, Amy L / Ransom, John T / Lee, David W / Speare, Sasha

Pain physician

2023 Volume 26, Issue 7, Page(s) E851–E857

Abstract: Background: Complex regional pain syndrome (CRPS) is an extremely painful disorder driven primarily by inflammation.: Objectives: We hypothesized that the immunomodulatory biologic, ExoFloTM, composed of bone marrow mesenchymal stem cell-derived ... ...

Abstract	Background: Complex regional pain syndrome (CRPS) is an extremely painful disorder driven primarily by inflammation. Objectives: We hypothesized that the immunomodulatory biologic, ExoFloTM, composed of bone marrow mesenchymal stem cell-derived extracellular vesicles, could be safely administered to CRPS patients and alleviate symptoms. Study design: Ten patients received 2 intravenous (IV) infusions, each containing 15 mL ExoFlo, on day one and day 4. A series of tests were performed at baseline (day 0, prior to infusion), week one, and months one, 3, and 6 after the second infusion. Setting: All patients were treated in one of 2 outpatient pain management clinics in Orange County, CA. Methods: Testing for clinical improvement included: visual analog scale of pain, brief pain inventory, 36-item short-form questionnaire, range of motion analysis, and jamar dynamometer testing. Results: No serious adverse events related to ExoFlo treatment occurred. Statistically significant improvements in pain and motion assessments occurred across the patient pool. Limitations: This study was limited by its patient number enrolled (10), it lacked a control arm, and one patient who dropped out of the study. Conclusions: IV delivery of ExoFlo appears safe in patients with CRPS. In addition, ExoFlo exhibited efficacy in addressing CRPS symptoms. Given the lack of effective and safe treatments available to CRPS patients, these results suggest that further studies are warranted to explore and validate this potential treatment for CRPS.
MeSH term(s)	Humans ; Treatment Outcome ; Complex Regional Pain Syndromes/therapy ; Pain ; Pain Management/methods ; Pain Measurement/methods
Language	English
Publishing date	2023-11-17
Publishing country	United States
Document type	Journal Article
ZDB-ID	2146393-1
ISSN	2150-1149 ; 1533-3159
ISSN (online)	2150-1149
ISSN	1533-3159
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