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  1. Article ; Online: Author's reply: To PMID 23148932.

    Lee, I S / Yook, J H

    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

    2013  Volume 39, Issue 7, Page(s) 805

    MeSH term(s) Female ; Gastrectomy ; Humans ; Lymph Node Excision ; Male ; Neoplasm Recurrence, Local/epidemiology ; Peritoneal Neoplasms/epidemiology ; Stomach Neoplasms/epidemiology ; Stomach Neoplasms/surgery
    Language English
    Publishing date 2013-07
    Publishing country England
    Document type Comment ; Letter
    ZDB-ID 632519-1
    ISSN 1532-2157 ; 0748-7983
    ISSN (online) 1532-2157
    ISSN 0748-7983
    DOI 10.1016/j.ejso.2013.03.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1149: Show issues Location:
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    Zs.MO 549: Show issues

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  2. Article: Effect of weight bearing exercise to improve bone mineral density in children with cerebral palsy: a meta-analysis.

    Kim, S J / Kim, S-N / Yang, Y-N / Lee, I-S / Koh, S-E

    Journal of musculoskeletal & neuronal interactions

    2017  Volume 17, Issue 4, Page(s) 334–340

    Abstract: Background: Despite widespread clinical use of weight bearing exercises to manage low bone mineral density (BMD) in children and adolescents with cerebral palsy (CP), previous studies have reported heterogeneous results on the effect of weight bearing ... ...

    Abstract Background: Despite widespread clinical use of weight bearing exercises to manage low bone mineral density (BMD) in children and adolescents with cerebral palsy (CP), previous studies have reported heterogeneous results on the effect of weight bearing exercise on BMD.
    Purpose: We performed the current meta-analysis to assess the effects of weight bearing exercise on increasing BMD in children who have CP with low BMD.
    Materials and methods: We searched PubMed, Cochrane, and Embase from inception through to October 2016 for studies that aims to investigate the effect of weight bearing exercise on BMD in children with CP. Following the searching result, the 118 relevant studies were reviewed and undergone selection process. Standardized mean difference (SMD), 95% confidence intervals (CIs) and p-values were calculated for analysis.
    Results: Three studies were ultimately included in the meta-analysis: one randomized-controlled study and two case-controlled studies. No significant difference was observed in the BMD of the lumbar spine between before treatment and after treatment (SMD,0.341; 95% CI,-0.647-1.330; p=0.449) but the BMD of the femur significantly improved after applying weight bearing exercise compared to pre-treatment values (SMD, 0.916; 95% CI, 0.382-1.114; p⟨0.001).
    Conclusions: Weight bearing exercise has a significant effect on improving BMD of the femur in children with CP.
    MeSH term(s) Adolescent ; Bone Density ; Cerebral Palsy/rehabilitation ; Child ; Female ; Humans ; Male ; Resistance Training/methods
    Language English
    Publishing date 2017-12-01
    Publishing country Greece
    Document type Journal Article ; Meta-Analysis
    ZDB-ID 2041366-X
    ISSN 1108-7161
    ISSN 1108-7161
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5401: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  3. Article ; Online: Functional neuroimaging studies in functional dyspepsia patients: a systematic review.

    Lee, I-S / Wang, H / Chae, Y / Preissl, H / Enck, P

    Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society

    2016  Volume 28, Issue 6, Page(s) 793–805

    Abstract: Background: There is increasing evidence in support of the presence of abnormal central changes (compared to healthy controls) in functional dyspepsia (FD) in addition to the peripheral changes in gastrointestinal tract.: Purpose: This systematic ... ...

    Abstract Background: There is increasing evidence in support of the presence of abnormal central changes (compared to healthy controls) in functional dyspepsia (FD) in addition to the peripheral changes in gastrointestinal tract.
    Purpose: This systematic review aims to provide an integrative understanding of the abnormal functional brain activity, visceral sensation, dyspeptic symptoms, and psychological changes of FD. Electronic and hand searches were conducted to identify functional neuroimaging studies involving FD patients. Sixteen studies were selected and divided into three categories: 10 resting state studies, three visceral distention studies, and three acupuncture studies. Changes were reported in several brain areas in FD patients including the frontal cortex, somatosensory cortex, insula, anterior cingulate cortex, thalamus, hippocampus, and amygdala. These brain activity changes were associated with visceral hypersensitivity, dyspeptic symptoms, poorer quality of life, anxiety, and depression. The results show that FD is associated with functional abnormalities in sensory and pain modulation, emotion, saliency, and homeostatic processing regions. The diversity of conditions, heterogeneous results, poorly standardized diagnoses of FD, and various comorbidities may be responsible for the variability in the results.
    Language English
    Publishing date 2016-06
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1186328-6
    ISSN 1365-2982 ; 1350-1925
    ISSN (online) 1365-2982
    ISSN 1350-1925
    DOI 10.1111/nmo.12793
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2979: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article: New constructive heuristics for the total weighted tardiness problem

    Yoon, S. H / Lee, I. S

    Journal of the Operational Research Society : OR Vol. 62, No. 1 , p. 232-237

    2011  Volume 62, Issue 1, Page(s) 232–237

    Author's details S. H. Yoon and I. S. Lee
    Language English
    Publisher Palgrave
    Publishing place Basingstoke, Hampshire
    Document type Article
    ZDB-ID 716033-1 ; 2069025-3
    ISSN 0030-3623 ; 1473-2858 ; 1473-284X
    ISSN 0030-3623 ; 1473-2858 ; 1473-284X
    Database ECONomics Information System

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  5. Article: Network Approaches to the genetic dissection of phenotypes in animals and humans

    Lee, I.S., Yonsei University, Seoul, Republic of korea

    Animal Cells and Systems

    (Apr 2013)  Volume v. 17, Issue (2), Page(s) p. 75–79

    Abstract: various genome-wide approaches to identifying the genetic components that underlie phenotypes in animals and humans have been developed during the last several decades. The relationship between gene and phenotype, however, cannot be represented by a ... ...

    Abstract various genome-wide approaches to identifying the genetic components that underlie phenotypes in animals and humans have been developed during the last several decades. The relationship between gene and phenotype, however, cannot be represented by a simple one-to-one correspondence. Rather, many genes are typically related to a single phenotype and many phenotypes can be associated with a single gene, a major theme not only identify the genetic components involved but also the relationships between genes.
    Keywords COMPLEXACION ; COMPLEXATION ; COMPLEXING
    Language English
    Document type Article
    ISSN 1976-8354
    Database AGRIS - International Information System for the Agricultural Sciences and Technology

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  6. Article ; Online: Comparative outcomes of robot-assisted minimally invasive versus open esophagectomy in patients with esophageal squamous cell carcinoma: a propensity score-weighted analysis.

    Yun, J K / Chong, B K / Kim, H J / Lee, I-S / Gong, C-S / Kim, B S / Lee, G D / Choi, S / Kim, H R / Kim, D K / Park, S-I / Kim, Y-H

    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    2019  Volume 33, Issue 5

    Abstract: Robots are increasingly used in minimally invasive surgery. We evaluated the clinical benefits of robot-assisted minimally invasive esophagectomy (RAMIE) in comparison with the conventional open esophageal surgery. From 2012 to 2016, 371 patients with ... ...

    Abstract Robots are increasingly used in minimally invasive surgery. We evaluated the clinical benefits of robot-assisted minimally invasive esophagectomy (RAMIE) in comparison with the conventional open esophageal surgery. From 2012 to 2016, 371 patients with esophageal squamous cell carcinoma underwent an Ivor Lewis or McKeown procedure at our institution. Of these, 130 patients underwent laparoscopic gastric conduit formation followed by RAMIE, whereas 241 patients underwent conventional esophageal surgery, including laparotomy and open esophagectomy (OE). We compared the short- and long-term clinical outcomes of these patients using the propensity score-based inverse probability of treatment weighting technique (IPTW). Among the early outcomes, the OE group showed a higher incidence of pneumonia (P = 0.035) and a higher requirement for vasopressors (P = 0.001). Regarding the long-term outcomes, all-cause mortality was significantly higher (P = 0.001) and disease-free survival was lower (P = 0.006) in the OE group. Wound-related problems also occurred more frequently in the OE group (P = 0.020) during the long-term follow-up. There was no statistical intergroup difference in the recurrence rates (P = 0.191). The Cox proportional-hazard analysis demonstrated that wound problems (HR 0.16, 95% CI 0.02-0.57; P = 0.017), pneumonia (HR 0.23, 95% CI 0.06-0.68; P = 0.019), and use of vasopressors (HR 0.14, 95% CI 0.08-0.25; P = 0.001) were independent predictors of mortality. RAMIE could be a better surgical option for selected patients with esophageal squamous cell carcinoma.
    MeSH term(s) Esophageal Neoplasms/surgery ; Esophageal Squamous Cell Carcinoma/surgery ; Esophagectomy/adverse effects ; Head and Neck Neoplasms ; Humans ; Minimally Invasive Surgical Procedures ; Neoplasm Recurrence, Local ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Propensity Score ; Robotic Surgical Procedures ; Robotics ; Treatment Outcome
    Language English
    Publishing date 2019-11-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639470-x
    ISSN 1442-2050 ; 1120-8694
    ISSN (online) 1442-2050
    ISSN 1120-8694
    DOI 10.1093/dote/doz071
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2378: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Biomimetic fibronectin/mineral and osteogenic growth peptide/mineral composites synthesized on calcium phosphate thin films.

    Chen, C / Qiu, Z Y / Zhang, S M / Lee, I-S

    Chemical communications (Cambridge, England)

    2011  Volume 47, Issue 39, Page(s) 11056–11058

    Abstract: Composites of fibronectin/mineral and osteogenic growth peptide/mineral were synthesized on calcium phosphate coated substrates immersed in Dulbecco's phosphate-buffered saline solution containing biomolecules. The kinetics of coprecipitation for two ... ...

    Abstract Composites of fibronectin/mineral and osteogenic growth peptide/mineral were synthesized on calcium phosphate coated substrates immersed in Dulbecco's phosphate-buffered saline solution containing biomolecules. The kinetics of coprecipitation for two biomolecules was similar, and the biomolecules participated in the formation of the crystal latticework and influenced the mineral structure and composition.
    MeSH term(s) Biomimetic Materials/chemical synthesis ; Biomimetic Materials/metabolism ; Calcium Phosphates/chemistry ; Calcium Phosphates/metabolism ; Chemical Precipitation ; Fibronectins/chemistry ; Fibronectins/metabolism ; Histones/chemistry ; Histones/metabolism ; Intercellular Signaling Peptides and Proteins/chemistry ; Intercellular Signaling Peptides and Proteins/metabolism ; Minerals/chemistry ; Minerals/metabolism
    Chemical Substances Calcium Phosphates ; Fibronectins ; Histones ; Intercellular Signaling Peptides and Proteins ; Minerals ; osteogenic growth peptide (132996-61-3) ; calcium phosphate (97Z1WI3NDX)
    Language English
    Publishing date 2011-10-21
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1472881-3
    ISSN 1364-548X ; 1359-7345 ; 0009-241X
    ISSN (online) 1364-548X
    ISSN 1359-7345 ; 0009-241X
    DOI 10.1039/c1cc13480a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Extraction and on-line concentration of flavonoids in Brassica oleracea by capillary electrophoresis using large volume sample stacking

    Lee, I. S. L. / Boyce, M. C. / Breadmore, M. C.

    Food chemistry

    2012  Volume 133, Issue 1, Page(s) 205

    Language English
    Document type Article
    ZDB-ID 243123-3
    ISSN 0308-8146
    Database Current Contents Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Z 3634: Show issues

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  9. Article ; Online: Polynucleotide phosphorylase (PNPase) is required for Salmonella enterica serovar Typhimurium colonization in swine.

    Bearson, S M D / Bearson, B L / Lee, I S / Kich, J D

    Microbial pathogenesis

    2013  Volume 65, Page(s) 63–66

    Abstract: The pnp gene encodes polynucleotide phosphorylase, an exoribonuclease involved in RNA processing and degradation. A mutation in the pnp gene was previously identified by our group in a signature-tagged mutagenesis screen designed to search for Salmonella ...

    Abstract The pnp gene encodes polynucleotide phosphorylase, an exoribonuclease involved in RNA processing and degradation. A mutation in the pnp gene was previously identified by our group in a signature-tagged mutagenesis screen designed to search for Salmonella enterica serovar Typhimurium genes required for survival in an ex vivo swine stomach content assay. In the current study, attenuation and colonization potential of a S. Typhimurium pnp mutant in the porcine host was evaluated. Following intranasal inoculation with 10(9) cfu of either the wild-type S. Typhimurium χ4232 strain or an isogenic derivative lacking the pnp gene (n = 5/group), a significant increase (p < 0.05) in rectal temperature (fever) was observed in the pigs inoculated with wild-type S. Typhimurium compared to the pigs inoculated with the pnp mutant. Fecal shedding of the pnp mutant was significantly reduced during the 7-day study compared to the wild-type strain (p < 0.001). Tissue colonization was also significantly reduced in the pigs inoculated with the pnp mutant compared to the parental strain, including the tonsils, ileocecal lymph nodes, Peyer's Patch region of the ileum, cecum and contents of the cecum (p < 0.05). The data indicate that the pnp gene is required for S. Typhimurium virulence and gastrointestinal colonization of the natural swine host.
    MeSH term(s) Animals ; Feces/microbiology ; Gastrointestinal Tract/microbiology ; Mutation ; Polyribonucleotide Nucleotidyltransferase/genetics ; Polyribonucleotide Nucleotidyltransferase/metabolism ; Salmonella Infections, Animal/enzymology ; Salmonella Infections, Animal/genetics ; Salmonella Infections, Animal/microbiology ; Salmonella typhimurium/enzymology ; Salmonella typhimurium/genetics ; Swine/microbiology ; Swine Diseases/enzymology ; Swine Diseases/genetics ; Swine Diseases/microbiology
    Chemical Substances Polyribonucleotide Nucleotidyltransferase (EC 2.7.7.8)
    Language English
    Publishing date 2013-12
    Publishing country England
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 632772-2
    ISSN 1096-1208 ; 0882-4010
    ISSN (online) 1096-1208
    ISSN 0882-4010
    DOI 10.1016/j.micpath.2013.10.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2136: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
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  10. Article: Biomimetic fibronectin/mineral and osteogenic growth peptide/mineral composites synthesized on calcium phosphate thin films

    Chen, C / Qiu, Z. Y / Zhang, S. M / Lee, I.-S

    Chemical communications. 2011 Sept. 27, v. 47, no. 39

    2011  

    Abstract: Composites of fibronectin/mineral and osteogenic growth peptide/mineral were synthesized on calcium phosphate coated substrates immersed in Dulbecco's phosphate-buffered saline solution containing biomolecules. The kinetics of coprecipitation for two ... ...

    Abstract Composites of fibronectin/mineral and osteogenic growth peptide/mineral were synthesized on calcium phosphate coated substrates immersed in Dulbecco's phosphate-buffered saline solution containing biomolecules. The kinetics of coprecipitation for two biomolecules was similar, and the biomolecules participated in the formation of the crystal latticework and influenced the mineral structure and composition.
    Keywords biomimetics ; bone formation ; calcium phosphates ; chemical communication ; chemical reactions ; coprecipitation ; fibronectins ; films (materials) ; peptides ; sodium chloride
    Language English
    Dates of publication 2011-0927
    Size p. 11056-11058.
    Publishing place The Royal Society of Chemistry
    Document type Article
    ZDB-ID 1472881-3
    ISSN 1364-548X ; 1359-7345 ; 0009-241X
    ISSN (online) 1364-548X
    ISSN 1359-7345 ; 0009-241X
    DOI 10.1039/c1cc13480a
    Database NAL-Catalogue (AGRICOLA)

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