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  1. Book ; Online ; E-Book: Internal limiting membrane surgery

    Lee, Ji-Eun / Byon, Ik Soo / Park, Sung Who

    2021  

    Abstract: This book describes and illustrates the various operative techniques employed in internal limiting membrane (ILM) surgery in patients with different macular diseases. Clear guidance is first provided on terminology, bearing in mind that, in the past, ... ...

    Author's details Ji-Eun Lee, Ik Soo Byon, Sung Who Park
    Abstract This book describes and illustrates the various operative techniques employed in internal limiting membrane (ILM) surgery in patients with different macular diseases. Clear guidance is first provided on terminology, bearing in mind that, in the past, methods and results have often been misread or misunderstood owing to confusing terms. Instruction is then given on handling of the ILM and the use of vital dyes and vitreous substitute. ILM peeling, ILM insertion, and ILM flap techniques are explained, and detailed descriptions are provided of the ILM surgical procedures currently performed in conditions such as macular hole, epiretinal membrane, diabetic macular edema, myopic tractional maculopathy, retinal detachment, and optic pit maculopathy. In addition, a chapter is devoted to the postoperative anatomical and functional changes to the macula after ILM surgery in order to help readers both to understand the mechanism of metamorphopsia and to reduce this symptom. The book will be an excellent up-to-date guide for all vitreoretinal surgeons.
    Keywords Retina/Surgery ; Vitreous body/Surgery
    Subject code 617.735059
    Language English
    Size 1 online resource (XI, 105 p. 61 illus., 54 illus. in color.)
    Edition 1st ed. 2021.
    Publisher Springer
    Publishing place Singapore
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 981-15-9403-1 ; 981-15-9402-3 ; 978-981-15-9403-8 ; 978-981-15-9402-1
    DOI 10.1007/978-981-15-9403-8
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Kimchi attenuates endoplasmic reticulum stress-induced hepatic steatosis in HepG2 cells and C57BL/6N mice.

    Yun, Ye-Rang / Lee, Ji-Eun

    Nutrition research (New York, N.Y.)

    2024  Volume 124, Page(s) 43–54

    Abstract: Kimchi is a traditional fermented food that contains abundant nutrients and functional ingredients with various health benefits. We previously reported that kimchi active components suppress hepatic steatosis caused by endoplasmic reticulum (ER) stress ... ...

    Abstract Kimchi is a traditional fermented food that contains abundant nutrients and functional ingredients with various health benefits. We previously reported that kimchi active components suppress hepatic steatosis caused by endoplasmic reticulum (ER) stress in vitro and in vivo. Therefore, we assessed the effect of kimchi on the inhibition of hepatic steatosis caused by ER stress in HepG2 cells and C57BL/6N mice to verify the hypothesis that kimchi may potentially inhibit nonalcoholic fatty liver disease. We investigated the effect of kimchi on cell viability and triglyceride concentrations in cells and on lipid profile, lipid accumulation, and expression of related genes in cells and mice with hepatic steatosis. A mechanistic study was also performed using the liver X receptor α agonist T0901317 and the AMP-activated protein kinase agonist AICAR. Kimchi was noncytotoxic and effectively reduced triglyceride concentrations and suppressed hepatic steatosis-related gene expression in cells and mice. Additionally, kimchi recovered weight loss, lowered the serum and liver tissue lipid profiles, suppressed lipid accumulation, and reduced the effects of T0901317 and AICAR on lipogenic gene expression in tunicamycin-treated mice. Our results highlight that kimchi could prevent hepatic steatosis caused by ER stress in cells and mice.
    MeSH term(s) Animals ; Endoplasmic Reticulum Stress/drug effects ; Mice, Inbred C57BL ; Humans ; Hep G2 Cells ; Triglycerides/blood ; Triglycerides/metabolism ; Male ; Liver/metabolism ; Liver/drug effects ; Fermented Foods ; Mice ; Aminoimidazole Carboxamide/analogs & derivatives ; Aminoimidazole Carboxamide/pharmacology ; Non-alcoholic Fatty Liver Disease/drug therapy ; Non-alcoholic Fatty Liver Disease/prevention & control ; Non-alcoholic Fatty Liver Disease/etiology ; Sulfonamides/pharmacology ; Ribonucleotides/pharmacology ; AMP-Activated Protein Kinases/metabolism ; Lipid Metabolism/drug effects ; Cell Survival/drug effects ; Liver X Receptors/metabolism ; Tunicamycin/pharmacology ; Lipogenesis/drug effects ; Fatty Liver/drug therapy ; Fatty Liver/prevention & control ; Benzenesulfonamides ; Fluorocarbons
    Chemical Substances Triglycerides ; Aminoimidazole Carboxamide (360-97-4) ; T0901317 ; Sulfonamides ; Ribonucleotides ; AICA ribonucleotide (F0X88YW0YK) ; AMP-Activated Protein Kinases (EC 2.7.11.31) ; Liver X Receptors ; Tunicamycin (11089-65-9) ; Benzenesulfonamides ; Fluorocarbons
    Language English
    Publishing date 2024-01-30
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 582432-1
    ISSN 1879-0739 ; 0271-5317
    ISSN (online) 1879-0739
    ISSN 0271-5317
    DOI 10.1016/j.nutres.2024.01.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Comparative Evaluation of Visual Performance and Patient Satisfaction following Cataract Surgery: A Retrospective Analysis of an Extended Depth-of-Focus Intraocular Lens and a Diffractive Multifocal Lens with Extended Depth of Focus.

    Han, Kwang Eon / Lee, Ji Eun

    Journal of clinical medicine

    2023  Volume 12, Issue 23

    Abstract: 1) Background: Cataract surgery has evolved significantly with the development of multifocal and extended depth-of-focus intraocular lenses (IOLs), driven by increasing patient desire for spectacle independence. (2) Methods: This retrospective, single- ... ...

    Abstract (1) Background: Cataract surgery has evolved significantly with the development of multifocal and extended depth-of-focus intraocular lenses (IOLs), driven by increasing patient desire for spectacle independence. (2) Methods: This retrospective, single-center study conducted on 86 eyes from 59 patients aged 40-80 years compared the performance and patient satisfaction of Symfony
    Language English
    Publishing date 2023-11-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12237368
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Diversity and community structure of ectomycorrhizal mycorrhizal fungi in roots and rhizosphere soil of

    Lee, Ji-Eun / Eom, Ahn-Heum

    Mycobiology

    2023  Volume 50, Issue 6, Page(s) 448–456

    Abstract: In this study, the roots and rhizosphere soil ... ...

    Abstract In this study, the roots and rhizosphere soil of
    Language English
    Publishing date 2023-01-04
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2631580-4
    ISSN 2092-9323 ; 1229-8093
    ISSN (online) 2092-9323
    ISSN 1229-8093
    DOI 10.1080/12298093.2022.2161974
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Effect of Silica in the Manufacture of Autologous Serum Eye Drops on Corneal Stromal Cells.

    Kim, Sangyoon / Lee, Ji Eun

    Cornea

    2023  Volume 43, Issue 3, Page(s) 372–377

    Abstract: Purpose: The aim of this study was to evaluate the effect of serum clot activator, silica (SiO 2 ), which may be used for making autologous serum eye drops, on human corneal fibroblasts.: Methods: Cultured human corneal fibroblasts were exposed to 10% ...

    Abstract Purpose: The aim of this study was to evaluate the effect of serum clot activator, silica (SiO 2 ), which may be used for making autologous serum eye drops, on human corneal fibroblasts.
    Methods: Cultured human corneal fibroblasts were exposed to 10%, 20%, and 30% silica for 1, 6, and 24 hours; methyl thiazolyl tetrazolium-based colorimetric assay was performed to determine the survival rate of fibroblasts and lactate dehydrogenase leakage assay to assess the cytotoxicity. The apoptotic response was evaluated by flow cytometric analysis and fluorescence staining with Annexin V and propidium iodide. Cellular morphology was evaluated by inverted phase-contrast light microscopy and electron microscopy.
    Results: The survival rate of human corneal fibroblasts and cytotoxicity showed both dose-dependent and time-dependent responses. The fluorescent micrograph and flow cytometry showed that as the exposure time increased, more cells underwent apoptosis or necrosis after treatment with 30% silica. When observed with light and electron microscopy, the number of corneal fibroblasts decreased and they were more detached from the dish. In addition, damaged corneal fibroblasts showed degenerative changes after exposure to 30% silica.
    Conclusions: Silica showed dose-dependent and time-dependent toxicity in human corneal fibroblasts. It is safer to keep the blood in tubes without a clot activator when manufacturing autologous serum eye drops to prevent possible corneal cytotoxicity.
    MeSH term(s) Humans ; Ophthalmic Solutions/pharmacology ; Cells, Cultured ; Cornea ; Apoptosis ; Fibroblasts ; Cell Survival
    Chemical Substances Ophthalmic Solutions
    Language English
    Publishing date 2023-11-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604826-2
    ISSN 1536-4798 ; 0277-3740
    ISSN (online) 1536-4798
    ISSN 0277-3740
    DOI 10.1097/ICO.0000000000003412
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1790: Show issues Location:
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  6. Article ; Online: Gut microbiome diversity and function during hibernation and spring emergence in an aquatic frog.

    Lee, Ji-Eun / Park, Jun-Kyu / Do, Yuno

    PloS one

    2024  Volume 19, Issue 2, Page(s) e0298245

    Abstract: The gut microbiota maintains a deeply symbiotic relationship with host physiology, intricately engaging with both internal (endogenous) and external (exogenous) factors. Anurans, especially those in temperate regions, face the dual challenges of ... ...

    Abstract The gut microbiota maintains a deeply symbiotic relationship with host physiology, intricately engaging with both internal (endogenous) and external (exogenous) factors. Anurans, especially those in temperate regions, face the dual challenges of significant external influences like hibernation and complex internal variances tied to different life histories. In our research, we sought to determine whether different life stages (juvenile versus adult) of the Japanese wrinkled frog (Glandirana rugosa) lead to distinct shifts in gut bacterial communities during winter (hibernation) and its subsequent transition to spring. As hypothesized, we observed a more pronounced variability in the gut bacterial diversity and abundance in juvenile frogs compared to their adult counterparts. This suggests that the gut environment may be more resilient or stable in adult frogs during their hibernation period. However, this pronounced difference was confined to the winter season; by spring, the diversity and abundance of gut bacteria in both juvenile and adult frogs aligned closely. Specifically, the variance in gut bacterial diversity and composition between winter and spring appears to mirror the frogs' ecological adaptations. During the hibernation period, a dominance of Proteobacteria suggests an emphasis on supporting intracellular transport and maintaining homeostasis, as opposed to active metabolism in the frogs. Conversely, come spring, an uptick in bacterial diversity coupled with a dominance of Firmicutes and Bacteroidetes points to an upsurge in metabolic activity post-hibernation, favoring enhanced nutrient assimilation and energy metabolism. Our findings highlight that the relationship between the gut microbiome and its host is dynamic and bidirectional. However, the extent to which changes in gut bacterial diversity and composition contribute to enhancing hibernation physiology in frogs remains an open question, warranting further investigation.
    MeSH term(s) Animals ; Gastrointestinal Microbiome/physiology ; Hibernation/physiology ; Seasons ; Anura ; Bacteria/genetics ; Ranidae/microbiology
    Language English
    Publishing date 2024-02-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0298245
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Strategies to deal with genetic analyzer-specific DNA methylation measurements.

    So, Moon Hyun / Lee, Ji Eun / Lee, Hwan Young

    Electrophoresis

    2024  

    Abstract: Targeted bisulfite sequencing using single-base extension (SBE) can be used to measure DNA methylation via capillary electrophoresis on genetic analyzers in forensic labs. Several accurate age prediction models have been reported using this method. ... ...

    Abstract Targeted bisulfite sequencing using single-base extension (SBE) can be used to measure DNA methylation via capillary electrophoresis on genetic analyzers in forensic labs. Several accurate age prediction models have been reported using this method. However, using different genetic analyzers with different software settings can generate different methylation values, leading to significant errors in age prediction. To address this issue, the study proposes and compares four methods as follows: (1) adjusting methylation values using numerous actual body fluid DNA samples, (2) adjusting methylation values using control DNAs with varying methylation ratios, (3) constructing new age prediction models for each genetic analyzer type, and (4) constructing new age prediction models that could be applied to all types of genetic analyzers. To test the methods for adjusting values using actual body fluid DNA samples, previously reported adjusting equations were used for blood/saliva DNA age prediction markers (ELOVL2, FHL2, KLF14, MIR29B2CHG/C1orf132, and TRIM59). New equations were generated for semen DNA age prediction markers (TTC7B, LOC401324/cg12837463, and LOC729960/NOX4) by drawing polynomial regression lines between the results of the three types of genetic analyzers (3130, 3500, and SeqStudio). The same method was applied to obtain adjustment equations using 11 control DNA samples. To develop new age prediction models for each genetic analyzer type, linear regression analysis was conducted using DNA methylation data from 150 blood, 150 saliva, and 62 semen samples. For the genetic analyzer-independent models, control DNAs were used to formulate equations for calibrating the bias of the data from each genetic analyzer, and linear regression analysis was performed using calibrated body fluid DNA data. In the comparison results, the genetic analyzer-specific models showed the highest accuracy. However, genetic analyzer-independent models through bias adjustment also provided accurate age prediction results, suggesting its use as an alternative in situations with multiple constraints.
    Language English
    Publishing date 2024-03-15
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 619001-7
    ISSN 1522-2683 ; 0173-0835
    ISSN (online) 1522-2683
    ISSN 0173-0835
    DOI 10.1002/elps.202300185
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1868: Show issues Location:
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  8. Article: Combination of Glycinamide and Ascorbic Acid Synergistically Promotes Collagen Production and Wound Healing in Human Dermal Fibroblasts.

    Lee, Ji Eun / Boo, Yong Chool

    Biomedicines

    2022  Volume 10, Issue 5

    Abstract: The purpose of this study is to present a novel strategy to enhance collagen production in cells. To identify amino acid analogs with excellent collagen production-enhancing effects, human dermal fibroblasts (HDFs) were treated with 20 kinds of amidated ... ...

    Abstract The purpose of this study is to present a novel strategy to enhance collagen production in cells. To identify amino acid analogs with excellent collagen production-enhancing effects, human dermal fibroblasts (HDFs) were treated with 20 kinds of amidated amino acids and 20 kinds of free amino acids, individually at 1 mM. The results showed that glycinamide enhanced collagen production (secreted collagen level) most effectively. Glycine also enhanced collagen production to a lesser degree. However, other glycine derivatives, such as N-acetyl glycine, N-acetyl glycinamide, glycine methyl ester, glycine ethyl ester, and glycyl glycine, did not show such effects. Glycinamide increased type I and III collagen protein levels without affecting
    Language English
    Publishing date 2022-04-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines10051029
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  9. Article ; Online: Resolvin D1 Inhibits Corneal Inflammation in

    Kim, Sang Yoon / Lee, Ji Eun

    Ocular immunology and inflammation

    2022  Volume 31, Issue 5, Page(s) 927–934

    Abstract: Purpose: To investigate the role of lipid mediator, resolvin D1 (RvD1), in corneal inflammation.: Methods: The anti-inflammatory effect of RvD1 on stimulated human corneal epithelial cells (HCECs) was assessed. C57BL/6 mice corneas were abraded and ... ...

    Abstract Purpose: To investigate the role of lipid mediator, resolvin D1 (RvD1), in corneal inflammation.
    Methods: The anti-inflammatory effect of RvD1 on stimulated human corneal epithelial cells (HCECs) was assessed. C57BL/6 mice corneas were abraded and treated with RvD1 after stimulation with
    Results: RvD1 significantly inhibited cytokine production in HCECs and mouse corneas, cervical DLNs, and spleens while stimulating interleukin-10 (IL-10) production. Corneal opacity development, thickening, and neutrophil infiltration significantly reduced in response to RvD1 stimulation in the
    Conclusion: RvD1 inhibited
    MeSH term(s) Animals ; Mice ; Humans ; Staphylococcus aureus ; Mice, Inbred C57BL ; Keratitis/drug therapy ; Keratitis/pathology ; Anti-Inflammatory Agents ; Cytokines ; Inflammation/drug therapy
    Chemical Substances resolvin D1 ; Anti-Inflammatory Agents ; Cytokines
    Language English
    Publishing date 2022-05-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 1193873-0
    ISSN 1744-5078 ; 0927-3948
    ISSN (online) 1744-5078
    ISSN 0927-3948
    DOI 10.1080/09273948.2022.2070504
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4004: Show issues Location:
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  10. Article: Annals of Pediatric Endocrinology & Metabolism is now indexed in the Emerging Sources Citation Index.

    Lee, Ji-Eun

    Annals of pediatric endocrinology & metabolism

    2019  Volume 24, Issue 1, Page(s) 1

    Language English
    Publishing date 2019-03-31
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2800460-7
    ISSN 2287-1292 ; 2287-1012
    ISSN (online) 2287-1292
    ISSN 2287-1012
    DOI 10.6065/apem.2019.24.1.1
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